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Deep Brain Stimulation to Reward Circuitry Alleviates Anhedonia in Refractory Major Depression
Open accessAbstract
Deep brain stimulation (DBS) to different sites allows interfering with dysfunctional network function implicated in major depression. Because a prominent clinical feature of depression is anhedonia--the inability to experience pleasure from previously pleasurable activities--and because there is clear evidence of dysfunctions of the reward system in depression, DBS to the nucleus accumbens might offer a new possibility to target depressive symptomatology in otherwise treatment-resistant depression. Three patients suffering from extremely resistant forms of depression, who did not respond to pharmacotherapy, psychotherapy, and electroconvulsive therapy, were implanted with bilateral DBS electrodes in the nucleus accumbens. Stimulation parameters were modified in a double-blind manner, and clinical ratings were assessed at each modification. Additionally, brain metabolism was assessed 1 week before and 1 week after stimulation onset. Clinical ratings improved in all three patients when the stimulator was on, and worsened in all three patients when the stimulator was turned off. Effects were observable immediately, and no side effects occurred in any of the patients. Using FDG-PET, significant changes in brain metabolism as a function of the stimulation in fronto-striatal networks were observed. No unwanted effects of DBS other than those directly related to the surgical procedure (eg pain at sites of implantation) were observed. Dysfunctions of the reward system--in which the nucleus accumbens is a key structure--are implicated in the neurobiology of major depression and might be responsible for impaired reward processing, as evidenced by the symptom of anhedonia. These preliminary findings suggest that DBS to the nucleus accumbens might be a hypothesis-guided approach for refractory major depression.
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“DBS targeting the NAc was shown to exert antidepressant, anxiolytic, and hedonic effects, notably in treatment-resistant depression (Bewernick et al. 2010; Giacobbe et al. 2009; Schlaepfer et al. 2008).”
From Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression (2018) · cites this paper as Schlaepfer et al. 2008
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In the citing paper
“deep brain stimulation applied via electrodes situated in the accumbens area/ventral internal capsule improves depressive symptoms in treatmentrefractory depression (Malone et al, 2009;Schlaepfer et al, 2008).”
From Neurocircuitry of Mood Disorders (2010) · cites this paper as Schlaepfer et al, 2008
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“and that deep brain stimulation applied via electrodes situated in the accumbens area/ventral internal capsule reportedly improves depressive symptoms in treatment-refractory depression (Schlaepfer et al. 2008).”
From Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression (2008) · cites this paper as Schlaepfer et al. 2008
In the citing paper
“Treatments with enhanced spatial specificity such as deep brain stimulation (DBS) or transcranial magnetic stimulation (TMS), aimed to restore region-specific hypoactivity, show great promise in alleviating treatment-resistant depression in even the most severe cases (2–10).”
From Emerging Role for Nucleus Accumbens Medium Spiny Neuron Subtypes in Depression (2017) · cites this paper as [8]
In the citing paper
“High frequency DBS of the NAc, among other regions, shows great promise in alleviating treatment-resistant depression, though its mechanism is still unclear (5, 8, 10).”
From Emerging Role for Nucleus Accumbens Medium Spiny Neuron Subtypes in Depression (2017) · cites this paper as [8]
In the citing paper
“patients responding to DBS of the NAc, a region more associated with reward and positive affect, report acutely improved motivation for pleasurable activities [99].”
From Deep brain stimulation for depression. (2022) · cites this paper as [99]
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“interaction with world targets can also be seen in people who suddenly have their mesolimbic dopamine systems artificially activated for the first time, such as by a newly-implanted brain stimulation electrode.”
From Evolving Concepts of Emotion and Motivation (2018) · cites this paper as Schlaepfer et al., 2008
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Citations
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
A new depression scale designed to be sensitive to change
Montgomery, S. A., & Åsberg, M. (1979) · British Journal of Psychiatry · doi:10.1192/bjp.134.4.382 · Cited by 13,962
Deep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059
A Randomized Trial of Deep-Brain Stimulation for Parkinson's Disease
Deuschl, G., Schade‐Brittinger, C., Krack, P., Volkmann, J., Schäfer, H., Bötzel, K., Daniels, C., Deutschlander, A. B., Dillmann, U., Eisner, W. E., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa060281 · Cited by 3,018
Self-citationBlood, A. J., & Zatorre, R. J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.191355898 · Cited by 2,814
Mayberg, H. S., Liotti, M., Brannan, S. K., McGinnis, S., Mahurin, R. K., Jerabek, P. A., Silva, J. A., Tekell, J. L., Martin, C. C., Lancaster, J. L., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.5.675 · Cited by 2,416
Anticipation of Increasing Monetary Reward Selectively Recruits Nucleus Accumbens
Knutson, B., Adams, C. M., Fong, G. W., & Hommer, D. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-16-j0002.2001 · Cited by 2,244
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
Berton, O., McClung, C. A., DiLeone, R. J., Krishnan, V., Renthal, W., Russo, S. J., Graham, D., Tsankova, N. M., Bolanos, C. A., Rios, M., et al. (2006) · Science · doi:10.1126/science.1120972 · Cited by 2,129
Abstract reward and punishment representations in the human orbitofrontal cortex
O'Doherty, J., Kringelbach, M. L., Rolls, E. T., Hornak, J., & Andrews, C. (2001) · Nature Neuroscience · doi:10.1038/82959 · Cited by 2,003
Limbic-cortical dysregulation: a proposed model of depression
(1997) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.9.3.471 · Cited by 1,585
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Mavridis, I. N., Boviatsis, E. I., & Anagnostopoulou, S. (2010) · Stereotactic and Functional Neurosurgery · doi:10.1159/000315465 · Cited by 1
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Halgren, A. S., Siegel, Z., Golden, R., & Bazhenov, M. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.28.402289 · Cited by 1
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Sturm, V. (2009) · Springer eBooks · doi:10.1007/978-3-211-84820-3_90
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Doma, A. (2014) · Springer eBooks · doi:10.1007/978-3-642-40384-2_35
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Justo, L. P., & Calil, H. M. (2015) · Springer eBooks · doi:10.1007/978-3-319-17795-3_11
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Grinde, B. (2012) · SpringerBriefs in well-being and quality of life research · doi:10.1007/978-94-007-4393-9_3
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Gelabert‐González, M., Relova, J. L., & Castro-García, A. (2013) · Medicina Clínica · doi:10.1016/j.medcli.2013.01.038
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Gersner, R., Rosenberg, O., & Dannon, P. N. (2012) · Clinical Practice · doi:10.2217/cpr.12.23
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Lévêque, M. (2013) · Springer eBooks · doi:10.1007/978-2-8178-0454-5_4
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Redden, W. M., & Manepalli, J. N. (2015) · Current Geriatrics Reports · doi:10.1007/s13670-015-0151-8
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Hägele, C. (2016) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-10061
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Carpenter, L. L., Philip, N. S., & O’Reardon, J. P. (2009) · Medical psychiatry · doi:10.3109/9781420084887.009
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Mavridis, I. N. (2016) · Operative Neurosurgery · doi:10.1227/neu.0000000000001423
Cordeiro, R. C. (2014) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
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Metadata
- Authors
- Schlaepfer, T. E., Cohen, M. X., Frick, C., Kosel, M., Brodesser, D., Axmacher, N., Joe, A. Y., Kreft, M., Lenartz, D., & Sturm, V.
- Affiliations
- Johns Hopkins University (US)
- University Hospital Bonn (DE)
- University Hospital Cologne (DE)
- Corresponding author
- Schlaepfer, Thomas E
- Venue
- Neuropsychopharmacology
- Published
- 2007-04-11
- Volume
- 33
- Issue
- 2
- Pages
- 368-377
- ISSN
- 0893-133X (ISSN-L)
- 1740-634X
- OpenAlex
- W2141467587
- Cited by
- 1,027
- References
- 61
- Citations by year
- 2026: 18 · 2025: 19 · 2024: 36 · 2023: 42 · 2022: 36 · 2021: 54 · 2020: 81 · 2019: 52 · 2018: 54 · 2017: 45 · 2016: 51 · 2015: 73 · 2014: 75 · 2013: 66 · 2012: 78
- FWCI
- 41.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Neuropsychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (acceptedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Keywords
- deep brain stimulation, nucleus accumbens, anhedonia, reward system dysfunction, brain metabolism, FDG-PET, fronto-striatal network, treatment-resistant depression
- MeSH terms
- Depressive Disorder, Double-Blind Method, Humans, Philosophy, Reward, Time Factors, Deep Brain Stimulation, Positron-Emission Tomography
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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