Activation and regulation of ATM kinase activity in response to DNA double-strand breaks

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Bakkenist, C. J., & Kastan, M. B. (2003) · Nature · doi:10.1038/nature01368 · Cited by 3,466

A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

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ATM Activation by DNA Double-Strand Breaks Through the Mre11-Rad50-Nbs1 Complex

Lee, J.-H., & Paull, T. T. (2005) · Science · doi:10.1126/science.1108297 · Cited by 1,424

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

Falck, J., Coates, J., & Jackson, S. P. (2005) · Nature · doi:10.1038/nature03442 · Cited by 1,304

The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response

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Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome

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Requirement of the MRN complex for ATM activation by DNA damage

Uziel, T., Lerenthal, Y., Moyal, L., Andegeko, Y., Mittelman, L., & Shiloh, Y. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg541 · Cited by 1,075

The DNA Double-Strand Break Repair Gene hMRE11 Is Mutated in Individuals with an Ataxia-Telangiectasia-like Disorder

Stewart, G. S., Maser, R. S., Stankovic, T., Bressan, D. A., Kaplan, M. I., Jaspers, N. G. J., Raams, A., Byrd, P. J., Petrini, J. H. J., & Taylor, A. M. R. (1999) · Cell · doi:10.1016/s0092-8674(00)81547-0 · Cited by 1,060

Requirement of ATM-Dependent Phosphorylation of Brca1 in the DNA Damage Response to Double-Strand Breaks

Cortez, D., Wang, Y., Qin, J., & Elledge, S. J. (1999) · Science · doi:10.1126/science.286.5442.1162 · Cited by 1,020

Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair

Botuyan, M. V., Lee, J., Ward, I. M., Kim, J., Thompson, J. R., Chen, J., & Mer, G. (2006) · Cell · doi:10.1016/j.cell.2006.10.043 · Cited by 1,011

A new Aven-ue to DNA-damage checkpoints

Gross, A. (2008) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2008.08.005 · Cited by 6

Retrospective screening of microarray data to identify candidate IFN-inducible genes in a HTLV-1 transformed model

Refaat, A., Owis, M. I., Abdelhamed, S., Saiki, I., & Sakurai, H. (2018) · Oncology Letters · doi:10.3892/ol.2018.8014 · Cited by 6

Synergic radiosensitization of sinomenine hydrochloride and radioiodine on human papillary thyroid carcinoma cells

Zhao, A., Zhang, J., Liu, Y., Jia, X., Lu, X., Wang, Q., Ji, T., Yang, L., Xue, J., Gao, R., et al. (2021) · Translational Oncology · doi:10.1016/j.tranon.2021.101172 · Cited by 6

Differential Activation of Cellular DNA Damage Responses by Replication-Defective and Replication-Competent Adenovirus Mutants

Prakash, A., Jayaram, S., & Bridge, E. (2012) · Journal of Virology · doi:10.1128/jvi.01757-12 · Cited by 6

DNA repair after DNA fragmentation in mouse small intestinal epithelial cells

Ogata, M., Oomori, T., Soga, H., Ota, Y., Itoh, A., Matsutani, T., Nanno, M., Suzuki, R., & Itoh, T. (2008) · Cell and Tissue Research · doi:10.1007/s00441-008-0727-0 · Cited by 6

TP53 and ATM mRNA expression in skin and skeletal muscle after low-level laser exposure

de Almeida, L. G., Sergio, L. P. D. S., de Paoli, F., Mencalha, A. L., & da Fonseca, A. D. S. (2017) · Journal of Cosmetic and Laser Therapy · doi:10.1080/14764172.2017.1293829 · Cited by 5

Ataxia telangiectasia mutated: The potential negative regulator in platelet-derived growth factor-BB promoted proliferation of pulmonary arterial smooth muscle cells

Qin, C., Zan, Y., Xie, L., & Liu, H. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.942251 · Cited by 5

Deep generative models in the quest for anticancer drugs: ways forward

Romanelli, V., Cerchia, C., & Lavecchia, A. (2024) · Frontiers in Drug Discovery · doi:10.3389/fddsv.2024.1362956 · Cited by 5

Post-Radiation Changes in The Number of Phosphorylated H2ax and Atm Protein Foci in Low Dose X-Ray Irradiated Human Mesenchymal Stem Cells

Chigasova, A. K., Pustovalova, M. V., Osipov, A. A., Korneva, S. A., Eremin, P. S., Yashkina, E. I., Ignatov, M. A., Fedotov, Y. А., Vorobyeva, N. Y., & Osipov, A. N. (2024) · Medical Radiology and radiation safety · doi:10.33266/1024-6177-2024-69-1-15-19 · Cited by 5

ATM/ATR‐Mediated DNA Damage Response Facilitates SARS‐CoV‐2 Spike Protein‐Induced Syncytium Formation

Zhao, X., Wei, T., Hou, Y., Wu, Y., Zhou, H., Meng, J., Wang, Q., & Liu, Y. (2024) · Journal of Medical Virology · doi:10.1002/jmv.70137 · Cited by 5

Next-generation Sequencing of an Ovarian Spindle Cell Tumor Identified an Ovarian Low-grade Endometrial Stromal Sarcoma: A Rare Entity

Choi, Y. J., Ho, J., Yoo, J. G., Liu, J., Lee, A., Park, J. S., & Hur, S. Y. (2018) · International Journal of Gynecological Pathology · doi:10.1097/pgp.0000000000000540 · Cited by 5

Crystal structure of the nuclease and capping domain of SbcD from Staphylococcus aureus

Lee, J., Jo, I., Ahn, J., Hong, S., Jeong, S., Kwon, A., & Ha, N. (2021) · The Journal of Microbiology · doi:10.1007/s12275-021-1012-0 · Cited by 5

Recent advancement of analytical approaches for assessing Ataxia telangiectasia mutated kinase inhibitors in Ataxia telangiectasia: An overview

Rameshkumar, A., Arunprasanna, V., Mahalakshmi, V. J., Raja, M. R., & Gopinath, K. (2024) · Process Biochemistry · doi:10.1016/j.procbio.2024.05.024 · Cited by 5

Clinical and genetic spectrum of Ataxia Telangiectasia Tunisian patients: Bioinformatic analysis unveil mechanisms of ATM variants pathogenicity

Jenni, R., Klaa, H., Khamessi, O., Chikhaoui, A., Najjar, D., Ghedira, K., Kraoua, I., Turki, I., & Yacoub‐Youssef, H. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134444 · Cited by 5

Hypoxia and the DNA Damage Response

Olcina, M. M., & Hammond, E. M. (2013) · Cancer drug discovery and develogment/Cancer drug discovery and development · doi:10.1007/978-1-4614-9167-5_2 · Cited by 5

19-(Benzyloxy)-19-oxojolkinolide B (19-BJB), an ent-abietane diterpene diepoxide, inhibits the growth of bladder cancer T24 cells through DNA damage

Wang, K., Yang, J., Jang, Y., Chen, G., Zhang, Y., Dai, Y.-H., Zhang, D., & Wu, Y. (2021) · PLoS ONE · doi:10.1371/journal.pone.0248468 · Cited by 6

The crosstalk between DNA damage response components and DNA-sensing innate immune signaling pathways

Lin, F., Tang, Y., & Zheng, C. (2021) · International Reviews of Immunology · doi:10.1080/08830185.2021.1898605 · Cited by 5

Limited Repair of Critical DNA Damage in Cells Exposed to Low Dose Radiation

Gaziev, A. I., & Shaikhaev, G. (2012) · InTech eBooks · doi:10.5772/33611 · Cited by 5

A novel bisindole-PBD conjugate causes DNA damage induced apoptosis via inhibition of DNA repair pathway

Sarma, P. N., Ramaiah, M. J., Kamal, Ä., Bhadra, U., & Bhadra, M. P. (2014) · Cancer Biology & Therapy · doi:10.4161/cbt.29705 · Cited by 5

Tobacco smoking, NBS1 polymorphisms, and survival in lung and upper aerodigestive tract cancers with semi-Bayes adjustment for hazard ratio variation

Yang, T., Chang, P.-Y., Park, S. L., Bastani, D., Chang, S., Morgenstern, H., Tashkin, D. P., Mao, J. T., Papp, J. C., Rao, J.-Y., et al. (2013) · Cancer Causes & Control · doi:10.1007/s10552-013-0303-0 · Cited by 5

A Hypomorphic Mutation Reveals a Stringent Requirement for the ATM Checkpoint Protein in Telomere Protection During Early Cell Division in Drosophila

Morciano, P., Zhang, Y., Cenci, G., & Rong, Y. S. (2013) · G3 Genes Genomes Genetics · doi:10.1534/g3.113.006312 · Cited by 5

A differential autophagy dependent response to DNA-double strand brakes in bone marrow mesenchymal stem cells from sporadic ALS patients

Wald-Altman, S., Pichinuk, E., Kakhlon, O., & Weil, M. (2017) · Disease Models & Mechanisms · doi:10.1242/dmm.027938 · Cited by 5

The Role of MRE11 in the IL-6/STAT3 Pathway of Lung Cancer Cells

Wu, C., Shu, L., Liu, H.-T., Cheng, Y., Wu, Y.-H., & Wu, Y.-H. (2022) · Current Issues in Molecular Biology · doi:10.3390/cimb44120418 · Cited by 4

Phased chromosome-level genome provides insights into the molecular adaptation for migratory lifestyle and population diversity for Pacific saury, Cololabis saira

Liu, Y., Luo, Y., Wang, P., Li, W., Tian, H., Cao, C., Ye, Z., Long, H., Lin, T., Wang, S., et al. (2024) · Communications Biology · doi:10.1038/s42003-024-07126-0 · Cited by 4

Genetically modified helminths as pharmaceutical biofactories

Walther, D., Smout, M. J., Giacomin, P., Brindley, P. J., Mitreva, M., Moyle, M., & Loukas, A. C. (2025) · Advances in Parasitology/Advances in parasitology · doi:10.1016/bs.apar.2025.08.001 · Cited by 4

Gal‐1 promotes lung cancer cell survival by enhancing PARP1 / H1 .2 interaction to promote DNA repair upon DNA damage response

Chen, Y., Liu, X., Li, B., Xie, X., Jin, X., & Sun, H. Z. (2025) · FEBS Journal · doi:10.1111/febs.70134 · Cited by 4

rs2735383, located at a microRNA binding site in the 3’UTR of NBS1, is not associated with breast cancer risk

Liu, J., Lončar, I., Collée, J. M., Bolla, M. K., Dennis, J., Michailidou, K., Wang, Q., Andrulis, I. L., Barile, M., Beckmann, M. W., et al. (2016) · Scientific Reports · doi:10.1038/srep36874 · Cited by 4

In vitro dexamethasone treatment does not induce alternative ATM transcripts in cells from Ataxia–Telangiectasia patients

Pozzi, E., Giorgio, E., Mancini, C., Buono, N. L., Augeri, S., Ferrero, M., Gregorio, E. D., Riberi, E., Vinciguerra, M., Nanetti, L., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-77352-z · Cited by 4

Immunohistochemical Expressions of AKT , ATM and Cyclin E in Oral Squamous Cell Carcinom

Khalil, A. A., & Sarkis, S. A. (2016) · Journal of Baghdad College of Dentistry · doi:10.12816/0031107 · Cited by 4

Human Mutations Affecting Reprogramming into Induced Pluripotent Stem Cells

Hayashi, Y. (2017) · AIMS Cell and Tissue Engineering · doi:10.3934/celltissue.2017.1.31 · Cited by 4

The chromosomal challenge of human embryos: Mechanisms and fundamentals

Ivanova, A. D., Korchivaia, E., Semenova, М. L., Лебедев, И. Н., Mazunin, I., & Volodyaev, I. (2025) · Human Genetics and Genomics Advances · doi:10.1016/j.xhgg.2025.100437 · Cited by 3

Bioinformatic and genomic analysis identifies C allele of APOE rs7412 as the most prominent variant limiting extreme human longevity

Satria, R. D., Sukorini, U., Lesmana, M. H. S., Irham, L. M., Adikusuma, W., Rahmawati, H., Harahap, N. I. F., Rinastiti, P., Wardhana, D. A., Sianipar, O., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-02848-5 · Cited by 5

DOSE-RATE EFFECT OF RADIATION ON RAT MAMMARY CARCINOGENESIS AND AN EMERGING ROLE FOR STEM CELL BIOLOGY

Imaoka, T., Nishimura, M., Daino, K., Hosoki, A., Kudo, K., Iizuka, D., Nagata, K., Takabatake, M., Nishimura, Y., Kokubo, T., et al. (2022) · Radiation Protection Dosimetry · doi:10.1093/rpd/ncac050 · Cited by 3

The Arp2/3 inhibitory protein Arpin inhibits homology‐directed DNA repair

Simanov, G., Rocques, N., Romero, S., de Koning, L., Vacher, S., Dubois, T., Bièche, I., & Gautreau, A. M. (2024) · Biology of the Cell · doi:10.1111/boc.202400073 · Cited by 3

Proteomic assessment of SKBR3/HER2+ breast cancer cellular response to Lapatinib and investigational Ipatasertib kinase inhibitors

Karcini, A., Mercier, N. R., & Lazar, I. M. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1413818 · Cited by 4

Genomic signature for oligometastatic disease in non-small cell lung cancer patients with brain metastases

Choi, A. R., D’Agostino, R. B., Farris, M. K., Abdulhaleem, M. N., Hunting, J. C., Wang, Y., Smith-Oliver, M. R., Ruiz, J., Lycan, T. W., Petty, W. J., et al. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1364021 · Cited by 3

ATM Expression and Activation in Ataxia Telangiectasia Patients with and without Class Switch Recombination Defects

Salami, F., Shad, T. M., Fathi, N., Mojtahedi, H., Esmaeili, M., Shahkarami, S., Afrakoti, L. G. M. P., Amirifar, P., Delavari, S., Nosrati, H., et al. (2025) · Journal of Clinical Immunology · doi:10.1007/s10875-025-01857-3 · Cited by 3

DNA Repair and Telomeres — An Intriguing Relationship

Boutou, E., Vlachodimitropoulos, D., Pappa, V., Stürzbecher, H.-W., & Constantinos, E. (2013) · InTech eBooks · doi:10.5772/56115 · Cited by 3

Association of Nijmegen Breakage Syndrome 1 Genotypes With Bladder Cancer Risk

CHEN, M., CHANG, W.-S., Shen, T., Gong, C., Lin, M., Wang, Z.-H., WANG, Y.-C., Chen, C., Wu, H., Bau, D., et al. (2020) · Anticancer Research · doi:10.21873/anticanres.14157 · Cited by 3

Laser microirradiation as a versatile system for probing protein recruitment and protein–protein interactions at DNA lesions in plants

Dadejová, M. N., Franek, M., & Dvořáčková, M. (2022) · New Phytologist · doi:10.1111/nph.18086 · Cited by 3

Differential Expression of Small Heat Shock Protein 27 (Hsp27) in Ataxia telangiectasia Brains

Chen, W., Kuizon, S., Chiou, B. L., Bolton, D. C., Pullarkat, R. K., & Junaid, M. A. (2009) · Neurochemical Research · doi:10.1007/s11064-009-9959-y · Cited by 3

Rad17, the clamp loader that loads more than clamps

Paull, T. T., & Lee, J. (2014) · The EMBO Journal · doi:10.1002/embj.201488223 · Cited by 5

Glioblastoma Stem Cells: New Insights In Therapeutic Strategies

Goffart, N., Dedobbeleer, M., & Rogister, B. (2014) · Future Neurology · doi:10.2217/fnl.14.56 · Cited by 3

3EZ, 20Ac-ingenol induces cell-specific apoptosis in cyclin D1 over-expression through the activation of ATR and downregulation of p-Akt

Miyata, S., Wang, L., & Kitanaka, S. (2017) · Leukemia Research · doi:10.1016/j.leukres.2017.08.007 · Cited by 3

Ethnic Features of Genetic Susceptibility to Breast Cancer

Bermisheva, M., Bogdanova, N. V., Gilyazova, I. R., Zinnatullina, G., Бисултанова, З. И., & Хуснутдинова, Э. К. (2018) · Russian Journal of Genetics · doi:10.1134/s1022795418020047 · Cited by 4

Mechanisms of genome instability in Hutchinson-Gilford progeria

Zhang, H., & Cao, K. (2016) · Frontiers in Biology · doi:10.1007/s11515-016-1435-x · Cited by 2

DDX11 interacts with PARP1 to facilitate PARylation, thereby promoting gallbladder cancer progression and conferring gemcitabine resistance

Gao, Y., Liu, J., Yao, X. Y., Gong, L., Luo, S., Zhao, C., Pu, S., & Gao, G. (2025) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2025155 · Cited by 2

Targeting of the cellular ATM rather than ATR kinase exhibits therapeutic potential during the lumpy skin disease virus infection in vivo and in vitro

Ren, S., Chen, H.-T., Wang, S., Rehman, Z. U., Gao, X., Yang, X. Y., Wang, X., Yin, X., Han, J., & Sun, Y. (2025) · Antiviral Research · doi:10.1016/j.antiviral.2025.106280 · Cited by 2

GSK3B directs DNA repair choice and determines tumor response to PARP1 inhibition independent of BRCA1

Allam, H., Acklin, S., Sadhukhan, R., Patra, M., & Xia, F. (2025) · Journal of Clinical Investigation · doi:10.1172/jci189956 · Cited by 3

The effect of mesenchymal stem cells administration on DNA repair gene expressions in critically ill COVID-19 patients: prospective controlled study

Işıksaçan, N., Adaş, G., Kasapoğlu, P., Çukurova, Z., Yılmaz, R., Yaşar, K. K., Irmak, D. K., Tunçel, F. C., Erdal, G. Ş., Gedikbaşı, A., et al. (2024) · Nucleosides Nucleotides & Nucleic Acids · doi:10.1080/15257770.2024.2327478 · Cited by 2

Plasma Proteomics of Type 2 Diabetes, Hypertension, and Co-Existing Diabetes/Hypertension in Thai Adults

Fakfum, P., Chuljerm, H., Parklak, W., Roytrakul, S., Phaonakrop, N., Lerttrakarnnon, P., & Kulprachakarn, K. (2024) · Life · doi:10.3390/life14101269 · Cited by 2

Tyrosyl-DNA-Phosphodiesterase

Dexheimer, T. S., Huang, S.-Y. N., Das, B. B., & Pommier, Y. G. (2011) · Cancer drug discovery and develogment/Cancer drug discovery and development · doi:10.1007/978-1-4614-0323-4_16 · Cited by 2

Radiation Therapy Towards Laser-Driven Particle Beams: An “OMICS” Approach in Radiobiology

Minafra, L., Bravatà, V., Cammarata, F. P., & Forte, G. I. (2016) · Biological and medical physics, biomedical engineering · doi:10.1007/978-3-319-31563-8_4 · Cited by 2

DNA Double Strand Break Repair: Mechanisms and Therapeutic Potential

Williamson, L. M., Williamson, C. T., & Lees‐Miller, S. P. (2009) · Springer eBooks · doi:10.1007/978-90-481-2561-6_8 · Cited by 2

Anti-silencing factor 1A is associated with genome stability maintenance of mouse preimplantation embryos†

Deng, K., Feng, W., Liu, X., Su, X., Zuo, E., Du, S., Huang, Y., Shi, D., & Lu, F. (2020) · Biology of Reproduction · doi:10.1093/biolre/ioaa001 · Cited by 2

DCLK1 and DNA Damage Response

Panneerselvam, J., Qu, D., Houchen, C. W., Bronze, M. S., & Chandrakesan, P. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.92327 · Cited by 2

Conserved SQ and QS motifs in bacterial effectors suggest pathogen interplay with the ATM kinase family during infectionPreprint

Sampietro, D., Sámano‐Sánchez, H., Davey, N. E., Sharan, M., Mészáros, B., Gibson, T. J., & Kumar, M. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/364117 · Cited by 3

Specifications of the ACMG/AMP variant curation guidelines for the analysis of germline ATM sequence variantsPreprint

Richardson, M. E., Holdren, M. A., Brannan, T., de la Hoya, M., Spurdle, A. B., Tavtigian, S. V., Young, C. C., Zec, L., Hiraki, S. C., Anderson, M. J., et al. (2024) · medRxiv · doi:10.1101/2024.05.28.24307502 · Cited by 2

Cellular effects after exposure to mixed beams of ionizing radiation

Staaf, E. (2012) · KTH Publication Database DiVA (KTH Royal Institute of Technology) · Cited by 2

Interaction of DDB1 with NBS1 in a DNA Damage Checkpoint Pathway

Lim, H. J., Lim, H. J., & Yoo, H. Y. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252313097 · Cited by 1

Studies on the functional role of UFMylation in cells (Review)

Qin, R., Tang, Y., Yuan, Y., Meng, F., Zheng, K., Yang, X., Zhao, J., & Yang, C.-H. (2025) · Molecular Medicine Reports · doi:10.3892/mmr.2025.13556 · Cited by 1

Genome rearrangements induced by the stimulation of end-joining of DNA double strand breaks through multiple phosphorylation of MRE11 by the kinase PKB/AKT1

Guirouilh‐Barbat, J., Boueya, I. L., Gelot, C., Pennarun, G., Granotier-Beckers, C., Dardillac, E., Yu, W., Lescale, C., Rass, E., Ariste, O., et al. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf468 · Cited by 1

Potential Mechanisms of MAP Kinase JNK’s Involvement in Modulating Cancer Cell Fate in a Cisplatin Concentration-Dependent Manner

Tenkutytė, M., Kalvelytė, A. V., & Stulpinas, A. (2026) · Pharmaceuticals · doi:10.3390/ph19030509 · Cited by 1

CYLD-mediated DNA damage coordinates pathological cardiac hypertrophy via RIPK1-dependent signaling

Jiang, X., Shi, M., Guo, J., Zhang, J., Li, D., 范祖军, Ren, F., Wu, S., Zeng, J., Wu, J., et al. (2026) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2026.03.005 · Cited by 1

Hydrogen Sulfide Signaling in Neurodegenerative Movement Disorders

Pieper, A. A., & Paul, B. D. (2025) · Handbook of experimental pharmacology · doi:10.1007/164_2025_757 · Cited by 1

Discrete modelling of p53-Mdm2 feedback loop

Ahmad, J., Niazi, U. K., & Ali, S. U. (2011) · IEEE International Conference on Granular Computing (GrC) · doi:10.1109/grc.2011.6122564 · Cited by 1

Role of Protein Linked DNA Breaks in Cancer

Allam, W. R., Ashour, M. E., Waly, A. A., & El‐Khamisy, S. F. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-60733-7_3 · Cited by 3

The miRNA binding site SNP in the 3′ UTR of NBS1 is inversely associated with breast cancer risk

Ghanei, N., Ghaedi, K., bidakani, M. M., Fazilati, M., & Nazem, H. (2018) · Journal of Cellular Immunotherapy · doi:10.1016/j.jocit.2018.09.013 · Cited by 1

Computational Analysis of Non-synonymous SNPs in ATM Kinase: Structural Insights, Functional Implications, and Inhibitor Discovery

Panchal, N. K., Samdani, P., Sengupta, T., & Prince, S. E. (2024) · Molecular Biotechnology · doi:10.1007/s12033-024-01120-x · Cited by 1

The ATM-mediated DNA-damage response

Shiloh, Y. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139046947.035 · Cited by 1

CHROMATIN STRUCTURE AND DNA DAMAGE RESPONSE

Normatova, M. (2017) · Avicenna Bulletin · doi:10.25005/2074-0581-2017-19-1-120-124 · Cited by 1

The Role of Stem Cell Genomic Instability in Aging

Sieben, C. J., Childs, B. G., & Baker, D. J. (2015) · Current Stem Cell Reports · doi:10.1007/s40778-015-0020-6 · Cited by 1

Interplay and Quality Control of DNA Damage Repair Mechanisms

Eppink, B., Essers, J., & Kanaar, R. (2011) · Wiley eBooks · doi:10.1002/9783527639991.ch16 · Cited by 1

Chemical Dissection of the Cell Cycle for Anticancer Drug Discovery and Target Identification

Lo, Y. (2016) · eScholarship (California Digital Library) · Cited by 1

Identification and characterization of novel genes involved in DNA double strand break repair process in the yeast Saccharomyces cerevisiae

Omidi, K. (2017) · Carleton University's Institutional Repository (MacOdrum Library, Carleton University) · doi:10.22215/etd/2017-11862 · Cited by 1

Nonhomologous DNA End Joining in Mammalian Cells

Ray, U., & Raghavan, S. C. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821618-7.00101-2 · Cited by 1

Cellular response to adenovirus and adeno- associated virus coinfection.

Bevington, J. M. (2009) · OhioLink ETD Center (Ohio Library and Information Network)

Formation and repair of complex DNA damage induced by ionizing radiation

Magnander, K. (2013) · Gothenburg University Publications Electronic Archive (Gothenburg University)

Estudo da integridade genômica durante o processo de diferenciação de células-tronco adultas em células com características neurais

Lambert, A. P. F., & Bonatto, D. (2009) · Americanae (AECID Library) · doi:10.13140/rg.2.2.10637.15841

The role of the PSD95/Dlg/ZO-1 (PDZ) binding motif of human papillomavirus type 18 E6 oncoprotein in the virus life cycle

Delury, C. P. (2012) · University of Birmingham Institutional Research Archive (University of Birmingham)

CHK2 is Negatively Regulated by Protein Phosphatase 2A

Freeman, A. K. (2010) · Digital Commons - University of South Florida (University of South Florida)

DNA Damage Repair Pathways and Synthetic Lethality

Ward, S. E. (2013) · Methods and principles in medicinal chemistry · doi:10.1002/9783527677252.ch08

DNA damage affecting thyroidal iodide transport: an explanation to thyroid stunning

Nordén, M. M. (2008) · Gothenburg University Publications Electronic Archive (Gothenburg University)

Studies on Mre11-ku interaction and its modulation by ionizing radiations

Sharma, A. (2010) · DuEPublico (University of Duisburg-Essen)

A theoretical investigation of protein recruitment during the DNA damage response and of the dynamics of DNA replication

Löb, D. (2013) · Technischen Universität Darmstadt · doi:10.26083/tuprints-00003556

Linking Human RecQ Helicases to DNA Damage Response and Aging

Cheng, W., Ahn, B., & Bohr, V. A. (2009) · Springer eBooks · doi:10.1007/978-90-481-2561-6_15

Role of checkpoint kinase 1 in malignant melanoma

Smith, J. (2013) · Enlighten: Theses (The University of Glasgow)

The mechanism of DNA double-strand break (DSB) resection in human cells

Yang, S.-H. (2013) · Texas ScholarWorks (Texas Digital Library)

Caractérisation et rôle de la phosphorylation de la protéine Rad51

Popova, M. (2009) · OpenGrey (Institut de l'Information Scientifique et Technique)

Enhanced Tel1ATM Checkpoint Signaling at Protein-Bound Double-Strand Breaks

Dodson, G. E., & Russell, P. R. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.05386-11

Functions of the MRE11-RAD50-NBS1 complex in DNA double strand break repair

Konkow, S. (2012) · DuEPublico (University of Duisburg-Essen)

PENTOSE PHOSPHATE PATHWAY IN HEALTH AND DISEASE: FROM METABOLIC DYSFUNCTION TO BIOMARKERS

Ramos, R. J. J. F. (2013)

Signalomics : unsupervised and global strategies to explore mechanisms of radioresistence in lung cancer cells

Ståhl, S. (2011) · Figshare

Doctorate School in Molecular Medicine Doctorate Program in Genetics and Molecular Medicine Coordinator: Prof. Lucio Nitsch XXVI Cycle New Therapeutic Perspective in CCDC6 Deficient Lung Cancer Cells

Morra, C. F. (2014)

Computational Prediction of Kinase-Substrate Interactions with Scansite 3 and the Enrichment of well-known Protein-Protein Interaction Networks with Novel and Relevant Interactors

Informatik, B. (2012)

Investigating the localization of an avian hairy homolog (c-Hairy1) protein

Cravo, J. A. (2013) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)

Cellular response pathways to formaldehyde

Graaf, D. C. (2009) · doi:10.6083/m41n7z38

DNA Repair, Overview

Barbe, J. H., O’Hayer, K., & Brody, J. R. (2017) · Springer eBooks · doi:10.1007/978-1-4419-0717-2_107

Coping with DNA Damage and Replication Stress

Ulrich, H. D. (2009) · Royal Society of Chemistry eBooks · doi:10.1039/9781847559852-00178

Multicolor Laser Scanning Confocal Immunofluorescence Microscopy of DNA Damage Response Biomarkers

Laubenthal, J., Gdula, M. R., Dhawan, A., & Anderson, D. C. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-529-3_16

ATM activation by DNA double-strand breaks through

Lee, J., & Paull, T. T. (2016)

ATM Activation by DNA Double-Strand Breaks Through the Mre11-Rad50-Nbs1 Complex

Lee, J.-H., & Paull, T. T. (2005) · Science · doi:10.1126/science.1108297 · Cited by 1,424

Characterization of the mechanisms of ATM activation by the MRN complex and DNA

Lee, J. H. (2005) · Texas ScholarWorks (Texas Digital Library)

Two-step activation of ATM by DNA and the Mre11–Rad50–Nbs1 complex

Dupré, A., Boyer-Châtenet, L., & Gautier, J. (2006) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1090 · Cited by 248

Direct Activation of the ATM Protein Kinase by the Mre11/Rad50/Nbs1 Complex

Lee, J.-H., & Paull, T. T. (2004) · Science · doi:10.1126/science.1091496 · Cited by 762