Activation and regulation of ATM kinase activity in response to DNA double-strand breaks

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Bakkenist, C. J., & Kastan, M. B. (2003) · Nature · doi:10.1038/nature01368 · Cited by 3,466

A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

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ATM Activation by DNA Double-Strand Breaks Through the Mre11-Rad50-Nbs1 Complex

Lee, J.-H., & Paull, T. T. (2005) · Science · doi:10.1126/science.1108297 · Cited by 1,424

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

Falck, J., Coates, J., & Jackson, S. P. (2005) · Nature · doi:10.1038/nature03442 · Cited by 1,304

The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response

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Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome

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Requirement of the MRN complex for ATM activation by DNA damage

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The DNA Double-Strand Break Repair Gene hMRE11 Is Mutated in Individuals with an Ataxia-Telangiectasia-like Disorder

Stewart, G. S., Maser, R. S., Stankovic, T., Bressan, D. A., Kaplan, M. I., Jaspers, N. G. J., Raams, A., Byrd, P. J., Petrini, J. H. J., & Taylor, A. M. R. (1999) · Cell · doi:10.1016/s0092-8674(00)81547-0 · Cited by 1,060

Requirement of ATM-Dependent Phosphorylation of Brca1 in the DNA Damage Response to Double-Strand Breaks

Cortez, D., Wang, Y., Qin, J., & Elledge, S. J. (1999) · Science · doi:10.1126/science.286.5442.1162 · Cited by 1,020

Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair

Botuyan, M. V., Lee, J., Ward, I. M., Kim, J., Thompson, J. R., Chen, J., & Mer, G. (2006) · Cell · doi:10.1016/j.cell.2006.10.043 · Cited by 1,011

The Chromatin Response to Double-Strand DNA Breaks and Their Repair

Aleksandrov, R., Hristova, R. H., Stoynov, S., & Gospodinov, A. G. (2020) · Cells · doi:10.3390/cells9081853 · Cited by 79

Parvovirus B19 Infection of Human Primary Erythroid Progenitor Cells Triggers ATR-Chk1 Signaling, Which Promotes B19 Virus Replication

Luo, Y., Lou, S., Deng, X., Liu, Z., Li, Y., Kleiboeker, S. B., & Qiu, J. (2011) · Journal of Virology · doi:10.1128/jvi.00831-11 · Cited by 75

Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum

Du, L., Kayalı, R., Bertoni, C., Fike, F. M., Hu, H., Iversen, P. L., & Gatti, R. A. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr217 · Cited by 74

The Mre11-Rad50-Nbs1 Complex Mediates Activation of TopBP1 by ATM

Yoo, H. Y., Kumagai, A., Shevchenko, A., Shevchenko, A., & Dunphy, W. G. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-12-1190 · Cited by 76

Long-term culture of mesenchymal stem cells impairs ATM-dependent recognition of DNA breaks and increases genetic instability

Hladik, D., Höfig, I., Oestreicher, U., Beckers, J., Matjanovski, M., Bao, X., Scherthan, H., Atkinson, M. J., & Rosemann, M. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1334-6 · Cited by 72

Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer

Schneider, L. S., von Schwarzenberg, K., Lehr, T., Ulrich, M. P., Kubisch-Dohmen, R., Liebl, J., Trauner, D. H., Menche, D., & Vollmar, A. M. (2015) · Cancer Research · doi:10.1158/0008-5472.can-14-2097 · Cited by 74

Promiscuous DNA synthesis by human DNA polymerase θ

Hogg, M., Sauer-Eriksson, A. E., & Johansson, E. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr1102 · Cited by 71

Hereditary Predisposition to Prostate Cancer: From Genetics to Clinical Implications

Brandão, A., Paulo, P., & Teixeira, M. R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21145036 · Cited by 74

The versatile functions of ATM kinase

Xu, B., & Boohaker, R. J. (2014) · Biomedical Journal · doi:10.4103/2319-4170.125655 · Cited by 71

Visualization of local DNA unwinding by Mre11/Rad50/Nbs1 using single-molecule FRET

Cannon, B. L., Kuhnlein, J., Yang, S.-H., Cheng, A., Schindler, D., Stark, J. M., Russell, R., & Paull, T. T. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1309816110 · Cited by 76

Rad17 Plays a Central Role in Establishment of the Interaction between TopBP1 and the Rad9-Hus1-Rad1 Complex at Stalled Replication Forks

Lee, J., & Dunphy, W. G. (2010) · Molecular Biology of the Cell · doi:10.1091/mbc.e09-11-0958 · Cited by 74

ATM regulates NF-κB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment

Fang, L., Choudhary, S., Zhao, Y., Edeh, C. B., Yang, C., Boldogh, I. R., & Brasier, A. R. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku529 · Cited by 73

Nanomedicine and epigenome. Possible health risks

Smolková, B., Dušinská, M., & Gábelová, A. (2017) · Food and Chemical Toxicology · doi:10.1016/j.fct.2017.07.020 · Cited by 73

Myc Is Required for Activation of the ATM-Dependent Checkpoints in Response to DNA Damage

Guerra, L., Albihn, A., Tronnersjö, S., Yan, Q., Guidi, R., Stenerlöw, B., Sterzenbach, T., Josenhans, C., Fox, J. G., Schauer, D. B., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008924 · Cited by 70

A Novel Aspect of Tumorigenesis—BMI1 Functions in Regulating DNA Damage Response

Lin, X., Ojo, D., Wei, F., Wong, N., Gu, Y. J., & Tang, D. (2015) · Biomolecules · doi:10.3390/biom5043396 · Cited by 72

Sp1 Facilitates DNA Double-Strand Break Repair through a Nontranscriptional Mechanism

Beishline, K., Kelly, C. M., Olofsson, B. A., Koduri, S., Emrich, J., Greenberg, R. A., & Azizkhan‐Clifford, J. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.00049-12 · Cited by 70

The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks

Lee, J., & Dunphy, W. G. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e13-01-0025 · Cited by 71

A DNA break– and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination

Vuong, B. Q., Herrick-Reynolds, K. M., Vaidyanathan, B., Pucella, J. N., Ucher, A. J., Donghia, N. M., Gu, X., Nicolás, L., Nowak, U. M., Rahman, N., et al. (2013) · Nature Immunology · doi:10.1038/ni.2732 · Cited by 67

Ku Regulates Signaling to DNA Damage Response Pathways through the Ku70 von Willebrand A Domain

Fell, V. L., & Schild‐Poulter, C. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.05661-11 · Cited by 67

Physical Interaction between the Herpes Simplex Virus Type 1 Exonuclease, UL12, and the DNA Double-Strand Break-Sensing MRN Complex

Balasubramanian, N., Bai, P., Buchek, G., Korza, G., & Weller, S. K. (2010) · Journal of Virology · doi:10.1128/jvi.01506-10 · Cited by 71

Chk2 Suppresses the Oncogenic Potential of DNA Replication-Associated DNA Damage

Stracker, T. H., Couto, S. S., Cordon‐Cardo, C., Matos, T., & Petrini, J. H. J. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.04.028 · Cited by 64

TDP1 serine 81 promotes interaction with DNA ligase IIIα and facilitates cell survival following DNA damage

Chiang, S., Carroll, J., & El‐Khamisy, S. F. (2010) · Cell Cycle · doi:10.4161/cc.9.3.10598 · Cited by 65

The Mre11 Complex and the Response to Dysfunctional Telomeres

Attwooll, C. L., Akpınar, M., & Petrini, J. H. J. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00479-09 · Cited by 66

Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination

Tavecchio, M., Munck, J. M., Cano, C., Newell, D. R., & Curtin, N. J. (2011) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-011-1662-4 · Cited by 63

Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors

Hartlerode, A. J., Morgan, M. J., Wu, Y., Buis, J. M., & Ferguson, D. O. (2015) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3072 · Cited by 69

PARP and CHK inhibitors interact to cause DNA damage and cell death in mammary carcinoma cells

Booth, L. A., Cruickshanks, N. A., Ridder, T. S., Dai, Y., Grant, S., & Dent, P. (2013) · Cancer Biology & Therapy · doi:10.4161/cbt.24424 · Cited by 62

Extracellular Signal-Regulated Kinases Modulate DNA Damage Response - A Contributing Factor to Using MEK Inhibitors in Cancer Therapy

Wei, F., Yan, J. J., & Tang, D. (2011) · Current Medicinal Chemistry · doi:10.2174/092986711798194388 · Cited by 63

Radiation-induced bystander effect and its clinical implications

Tang, H., Cai, L., He, X., Niu, Z., Huang, H., Hu, W., Bian, H., & Huang, H. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1124412 · Cited by 61

UBR5-mediated ubiquitination of ATMIN is required for ionizing radiation-induced ATM signaling and function

Zhang, T., Cronshaw, J. M., Kanu, N., Snijders, A. P., & Behrens, A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1400230111 · Cited by 61

Melatonin protects spermatogonia from the stress of chemotherapy and oxidation via eliminating reactive oxidative species

Zhang, X., Qin, X., Wei, R., Song, H., Mi, J., Lin, Z., Yang, Y., Sun, Z., & Zou, K. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.04.009 · Cited by 61

UV-induced histone H2AX phosphorylation and DNA damage related proteins accumulate and persist in nucleotide excision repair-deficient XP-B cells

Oh, K.-S., Bustin, M., Mazur, S. J., Appella, E., & Kraemer, K. H. (2011) · DNA Repair · doi:10.1016/j.dnarep.2010.09.004 · Cited by 60

Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy

Hong, Z., Liu, T., Wan, L., Fa, P., Kumar, P., Cao, Y., Prasad, C. B., Qiu, Z., Liu, J., Wang, H., et al. (2022) · Cancer Research · doi:10.1158/0008-5472.can-21-2229 · Cited by 60

The RING Finger Protein RNF8 Ubiquitinates Nbs1 to Promote DNA Double-strand Break Repair by Homologous Recombination

Lu, C.-S., Truong, L. N., Aslanian, A., Shi, L. Z., Li, Y., Hwang, P. Y.-H., Koh, K. H., Hunter, T. R., Yates, J. R., Berns, M. W., et al. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.421545 · Cited by 63

Low doses of X-rays induce prolonged and ATM-independent persistence of γH2AX foci in human gingival mesenchymal stem cells

Osipov, A. N., Pustovalova, M. V., Grekhova, A., Eremin, P. S., Vorobyova, N. Y., Pulin, A. A., Zhavoronkov, A. A., Roumiantsev, S. A., Klokov, D. Y., & Eremin, I. I. (2015) · Oncotarget · doi:10.18632/oncotarget.4739 · Cited by 60

The end protection problem—an unexpected twist in the tail

Ruis, P., & Boulton, S. J. (2021) · Genes & Development · doi:10.1101/gad.344044.120 · Cited by 57

ISG15 conjugation to proteins on nascent DNA mitigates DNA replication stress

Wardlaw, C. P., & Petrini, J. H. J. (2022) · Nature Communications · doi:10.1038/s41467-022-33535-y · Cited by 57

The MRN complex

Rupnik, A., Grenon, M., & Lowndes, N. F. (2008) · Current Biology · doi:10.1016/j.cub.2008.03.040 · Cited by 57

Concordance of ATM (Ataxia Telangiectasia Mutated) Immunohistochemistry between Biopsy or Metastatic Tumor Samples and Primary Tumors in Gastric Cancer Patients

Kim, H. S., Kim, M. A., Hodgson, D., Harbron, C., Wellings, R. P., O’Connor, M. J., Womack, C., Yin, X., Bang, Y., Im, S.-A., et al. (2013) · Pathobiology · doi:10.1159/000346034 · Cited by 57

Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex

Fernández, I. S., Yamashita, A., Arias‐Palomo, E., Bamba, Y., Bartolomé, R. A., Canales, Á., Teixidó, J., Ohno, S., & Llorca, Ó. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq749 · Cited by 57

New therapeutic perspectives in CCDC 6 deficient lung cancer cells

Morra, F., Luise, C., Visconti, R., Staibano, S., Merolla, F., Ilardi, G., Guggino, G., Paladino, S., Sarnataro, D., Franco, R., et al. (2014) · International Journal of Cancer · doi:10.1002/ijc.29263 · Cited by 56

Differential Requirements of the C Terminus of Nbs1 in Suppressing Adenovirus DNA Replication and Promoting Concatemer Formation

Lakdawala, S. S., Schwartz, R. A., Ferenchak, K., Carson, C. T., McSharry, B. P., Wilkinson, G. W. G., & Weitzman, M. D. (2008) · Journal of Virology · doi:10.1128/jvi.00900-08 · Cited by 55

Stemness factor Sall4 is required for DNA damage response in embryonic stem cells

Xiong, J., Todorova, D., Su, N., Kim, J., Lee, P.-J., Shen, Z., Briggs, S. P., & Xu, Y. (2015) · The Journal of Cell Biology · doi:10.1083/jcb.201408106 · Cited by 56

Nanotube-Based Colorimetric Probe for Ultrasensitive Detection of Ataxia Telangiectasia Mutated Protein

Zhang, Q., Zhao, B., Yan, J., Song, S., Min, R., & Fan, C. (2011) · Analytical Chemistry · doi:10.1021/ac2023684 · Cited by 55

The protective effect of biochanin A against rotenone-induced neurotoxicity in mice involves enhancing of PI3K/Akt/mTOR signaling and beclin-1 production

El-Sherbeeny, N. A., Soliman, N., Youssef, A. M., El‐Fadeal, N. M. A., El-Abaseri, T. B., Hashish, A. A., Abdelbasset, W. K., Batiha, G. E., & Zaitone, S. A. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111344 · Cited by 53

The homologous recombination system of Ustilago maydis

Holloman, W. K., Schirawski, J., & Holliday, R. (2008) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2008.04.006 · Cited by 52

Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response

Lee, H.-J., Lan, L., Peng, G., Chang, W., Hsu, M., Wang, Y., Cheng, C. C., Wei, L., Nakajima, S., Chang, S.-S., et al. (2015) · Cell Research · doi:10.1038/cr.2015.8 · Cited by 57

Dbf4 Is Direct Downstream Target of Ataxia Telangiectasia Mutated (ATM) and Ataxia Telangiectasia and Rad3-related (ATR) Protein to Regulate Intra-S-phase Checkpoint

Lee, A. Y., Chiba, T., Truong, L. N., Cheng, A. N., Do, J. P. H., Cho, M. J., Chen, L., & Wu, X. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.291104 · Cited by 55

DNA damage mediated transcription arrest: Step back to go forward

Mullenders, L. H. F. (2015) · DNA repair · doi:10.1016/j.dnarep.2015.09.005 · Cited by 51

Telomerase-Independent Paths to Immortality in Predictable Cancer Subtypes

Durant, S. T. (2012) · Journal of Cancer · doi:10.7150/jca.3965 · Cited by 52

Progeroid Syndromes and UV-Induced Oxidative DNA Damage

Kamenisch, Y., & Berneburg, M. (2009) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1038/jidsymp.2009.6 · Cited by 50

Oxidative stress and the multifaceted roles of ATM in maintaining cellular redox homeostasis

Lee, J. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103269 · Cited by 54

Three-dimensional topology of the SMC2/SMC4 subcomplex from chicken condensin I revealed by cross-linking and molecular modelling

Barysz, H. M., Kim, J. H., Chen, Z. A., Hudson, D. F., Rappsilber, J., Gerloff, D. L., & Earnshaw, W. C. (2015) · Open Biology · doi:10.1098/rsob.150005 · Cited by 52

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

Kanu, N., Zhang, T., Burrell, R. A., Chakraborty, A., Cronshaw, J. M., DaCosta, C., Gronroos, E. C., Pemberton, H. N., Anderton, E., Gonzalez, L., et al. (2015) · Oncogene · doi:10.1038/onc.2015.427 · Cited by 52

Novel insights into the pathophysiology of chemotherapy-induced damage to the ovary

Bedoschi, G., Navarro, P. A., & Oktay, K. (2019) · Panminerva Medica · doi:10.23736/s0031-0808.18.03494-8 · Cited by 50

MRE11 complex links RECQ5 helicase to sites of DNA damage

Zheng, L., Kanagaraj, R., Mihaljević, B., Schwendener, S., Sartori, A. A., Gerrits, B., Shevelev, I., & Janščák, P. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp147 · Cited by 53

Mechanisms of leukemia translocations

Nickoloff, J. A., Haro, L. P. D., Wray, J. W., & Hromas, R. (2008) · Current Opinion in Hematology · doi:10.1097/moh.0b013e328302f711 · Cited by 50

PARP inhibitors alone and in combination with other biological agents in homologous recombination deficient epithelial ovarian cancer: From the basic research to the clinic

Gadducci, A., & Guerrieri, M. E. (2017) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2017.04.006 · Cited by 51

TAK1 inhibitor 5Z-7-oxozeaenol sensitizes neuroblastoma to chemotherapy

Fan, Y., Cheng, J., Vasudevan, S. A., Patel, R. H., Li, L., Xu, X. Y., Zhao, Y., Jia, W., Lu, F., Zhang, H., et al. (2013) · APOPTOSIS · doi:10.1007/s10495-013-0864-0 · Cited by 49

Long story short: p53 mediates innate immunity

Miciak, J. J., & Bunz, F. (2016) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2016.03.001 · Cited by 49

Clinical potential of ATM inhibitors

Lavin, M. F., & Yeo, A. J. (2020) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2020.111695 · Cited by 51

NER and HR pathways act sequentially to promote UV-C-induced germ cell apoptosis in Caenorhabditis elegans

Stergiou, L., Eberhard, R., Doukoumetzidis, K., & Hengartner, M. O. (2011) · Cell Death & Differentiation · doi:10.1038/cdd.2010.158 · Cited by 48

The Mre11/Rad50/Nbs1 complex: Recent insights into catalytic activities and ATP-driven conformational changes

Paull, T. T., & Deshpande, R. A. (2014) · Experimental Cell Research · doi:10.1016/j.yexcr.2014.07.007 · Cited by 54

A genome-wide association study of calf birth weight in Holstein cattle using single nucleotide polymorphisms and phenotypes predicted from auxiliary traits

Cole, J. B., Waurich, B., Wensch-Dorendorf, M., Bickhart, D. M., & Swalve, H. H. (2014) · Journal of Dairy Science · doi:10.3168/jds.2013-7409 · Cited by 48

Finding the Genetic Determinants of Adverse Reactions to Radiotherapy

Rattay, T., & Talbot, C. J. (2014) · Clinical Oncology · doi:10.1016/j.clon.2014.02.001 · Cited by 48

Temporal Regulation of the Mre11-Rad50-Nbs1 Complex during Adenovirus Infection

Karen, K. A., Hoey, P. J., Young, C. S. H., & Hearing, P. (2009) · Journal of Virology · doi:10.1128/jvi.00042-09 · Cited by 49

Signaling to the p53 Tumor Suppressor through Pathways Activated by Genotoxic and Non-Genotoxic Stresses

Anderson, C. W., & Appella, E. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374145-5.00264-3 · Cited by 49

Studying the DNA damage response using in vitro model systems

Garner, E., & Costanzo, V. (2009) · DNA repair · doi:10.1016/j.dnarep.2009.04.015 · Cited by 47

cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cells

Cho, E.-A., Kim, E., Kwak, S.-J., & Juhnn, Y. (2014) · Molecular Cancer · doi:10.1186/1476-4598-13-36 · Cited by 47

Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury

Chandrakesan, P., May, R. J., Weygant, N., Qu, D., Berry, W. L., Sureban, S. M., Ali, N., Rao, C. V., Huycke, M. M., Bronze, M. S., et al. (2016) · Scientific Reports · doi:10.1038/srep37667 · Cited by 47

Is there still a role for cytotoxic chemotherapy after targeted therapy and immunotherapy in metastatic melanoma? A case report and literature review

Simon, A., Kourié, H. R., & Kerger, J. N. (2017) · 癌症：英文版 · doi:10.1186/s40880-017-0179-6 · Cited by 46

ATM: Translating the DNA Damage Response to Adaptive Immunity

Weitering, T. J., Takada, S., Weemaes, C. M. R., van Schouwenburg, P. A., & van der Burg, M. (2021) · Trends in Immunology · doi:10.1016/j.it.2021.02.001 · Cited by 47

Targeting the ATM pathway in cancer: Opportunities, challenges and personalized therapeutic strategies

Lee, J. (2024) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2024.102808 · Cited by 50

Rad50 Zinc Hook Is Important for the Mre11 Complex to Bind Chromosomal DNA Double-stranded Breaks and Initiate Various DNA Damage Responses

He, J. N., Shi, L. Z., Truong, L. N., Lu, C.-S., Razavian, N. B., Li, Y., Negrete, A., Shiloach, J., Berns, M. W., & Wu, X. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.384750 · Cited by 47

Mesenchymal stromal cells from amniotic fluid are less prone to senescence compared to those obtained from bone marrow: An in vitro study

Alessio, N., Pipino, C., Mandatori, D., Tomo, P. D., Ferone, A., Marchiso, M., Melone, M. A. B., Peluso, G., Pandolfi, A., & Galderisi, U. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26845 · Cited by 45

ATM-like kinases and regulation of telomerase: lessons from yeast and mammals

Sabourin, M., & Zakian, V. A. (2008) · Trends in Cell Biology · doi:10.1016/j.tcb.2008.04.004 · Cited by 45

ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle

Ray, A., Blevins, C., Wani, G., & Wani, A. A. (2016) · PLOS ONE · doi:10.1371/journal.pone.0159344 · Cited by 44

Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages

Solhaug, A., Holme, J. A., Haglund, K., Dendelé, B., Sergent, O., Pestka, J. J., Lagadic‐Gossmann, D., & Eriksen, G. S. (2013) · Toxicology Letters · doi:10.1016/j.toxlet.2013.02.012 · Cited by 44

Parvovirus Infection-Induced DNA Damage Response

Luo, Y., & Qiu, J. (2013) · Future Virology · doi:10.2217/fvl.13.5 · Cited by 46

Theabrownin triggers DNA damage to suppress human osteosarcoma U2 OS cells by activating p53 signalling pathway

Jin, W., Zhou, L., Yan, B., Li, Y., Liu, F., Tong, P., Yu, W., Dong, X., Xie, L., Zhang, J., et al. (2018) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13742 · Cited by 44

TAK1 ubiquitination regulates doxorubicin-induced NF-κB activation

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Excess growth hormone suppresses DNA damage repair in epithelial cells

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