Chia seeds: An ancient grain trending in modern human diets

Melo, Diana; Machado, Thelma B.; Oliveira, M. Beatriz P. P.

doi:10.1039/c9fo00239a

Cited by 82Seed and Plant BiochemistryFood composition and propertiesConsumer Attitudes and Food Labeling

Chia seeds: An ancient grain trending in modern human diets

Melo, Diana, Machado, Thelma B., Oliveira, M. Beatriz P. P.·2019·Food & Function

DOI 10.1039/c9fo00239a

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Abstract

Currently, in order to ensure adequate intake of nutrients to complement the normal diet, the consumption of seeds such as Salvia hispanica L. (commonly known as chia seeds) is increasing. For this reason, investigations concerning the composition and potential health effects of chia seeds are being carried out. Moreover, the recent approval of chia seeds as a Novel Food by the European Parliament allows its consumption and incorporation in a wide range of foods; thus, they have become widely available. Concerning their nutritional aspects, chia seeds are an excellent source of fat (20% to 34%), particularly polyunsaturated fatty acids such as α-linolenic (60%) and linoleic (20%) acids. Moreover, high levels of protein (16% to 26%), mainly prolamins, and dietary fibre contents (23% to 41%) have been reported. Vitamins (mostly B complex) and minerals (calcium, phosphorus, and potassium, among others) have also been described in appreciable amounts. Additionally, due to the absence of gluten, these seeds are appropriate for coeliac patients. Regarding other bioactive compounds, chia seeds are also a source of antioxidants, such as chlorogenic and caffeic acids, quercetin and kaempferol. Due to their described composition, chia seeds have been related to different medicinal effects, particularly anti-inflammatory and antidiabetic activities and positive effects on cardiovascular disease and hypertension. The aim of this paper is to perform a systematic review of chia seeds to provide an update of the knowledge about their morphology, nutritional and chemical composition, possible human health benefits and role as a functional food.

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Fiber content in chia seeds plays a vital role in treating diabetes by slowing down the release of glucose and the digestion process in the body.
“The fiber content in chia seeds also plays a vital role in treating diabetes by slowing down the release of glucose and the digestion process in the body [120].”
From Nutritional and Functional New Perspectives and Potential Health Benefits of Quinoa and Chia Seeds (2023) · cites this paper as [120]
Chia seeds are a rich source of dietary fiber, and fiber in the diet increases stool volume and prevents diseases such as diverticulosis and cancer.
“In addition, chia seeds are also a rich source of dietary fiber, providing various medicinal benefits as fiber in the diet increases stool volume and prevents diseases such as diverticulosis and even cancer.”
From Nutritional and Functional New Perspectives and Potential Health Benefits of Quinoa and Chia Seeds (2023) · cites this paper as [120]

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Fernández‐López, J., Lucas‐González, R., Viuda‐Martos, M., Sayas‐Barberá, E., & Pérez‐Álvarez, J. Á. (2018) · Plant Foods for Human Nutrition · doi:10.1007/s11130-018-0670-5 · Cited by 31 · see citing works
Protein digestibility of chia seed Salvia Hispanica L
Monroy‐Torres, R., Mancilla-Escobar, M. L., Gallaga-Solórzano, J. C., SergioMedina-Godoy, & Santiago-García., E. J. (2008) · RESPYN Revista de Salud Pública y Nutrición · Cited by 26 · see citing works
Stabilization of winterized cottonseed oil with chia (Salvia hispanica l.) seed extract at ambient temperature
Azeem, W., Nadeem, M. F., & Ahmad, S. (2015) · Journal of Food Science and Technology · doi:10.1007/s13197-015-1823-2 · Cited by 26 · see citing works
PHARMACOLOGICAL PROPERTIES OF SALVIA HISPANICA (CHIA) SEEDS: A REVIEW
Gazem, R. A. A., & Chandrashekariah, S. A. (2016) · MyPrints@UOM (Mysore University Library) · Cited by 26 · see citing works
Omega 3 Chia Seed Loading as a Means of Carbohydrate Loading
Illian, T. G., Casey, J. C., & Bishop, P. A. (2010) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0b013e3181fef85c · Cited by 22 · see citing works
Characterization and Bioaccessibility of Minerals in Seeds of Salvia hispanica L.
Barreto, A. D., Gutierrez, É. M. R., Silva, M. R., Silva, F. O., Silva, N. D. O. C. E., Lacerda, I. C. A., Labanca, R. A., & de Araújo, R. L. B. (2016) · American Journal of Plant Sciences · doi:10.4236/ajps.2016.715204 · Cited by 22 · see citing works
Antihypertensive and Antioxidant Effects of Functional Foods Containing Chia (Salvia hispanica) Protein Hydrolysates
M., I. U., Maira, R., Luis, A., & David, A. (2012) · InTech eBooks · doi:10.5772/30993 · Cited by 11 · see citing works
Dermatitis Caused by Ingestion of Chia Seeds
Tomás‐Pérez, M., Entrala, A., Bartolomé, B., Caballero, M. L., & Quirce, S. (2018) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0203 · Cited by 11 · see citing works
Vegetable oils rich in alpha linolenic acid allow a higher accretion of n-3 LCPUFA in the plasma, liver and adipose tissue of the rat
Valenzuela, R., Barrera, C. R., Ayala, J., Julio Sanhueza, C., & Valenzuela, A. (2014) · Grasas y Aceites · doi:10.3989/gya.110113 · Cited by 8 · see citing works
Biofunctionality of Chia (Salvia hispanica L.) Protein Hydrolysates
Campos, M. R. S., Chel‐Guerrero, L., Rosado-Rubio, J. G., & Betancur‐Ancona, D. (2016) · Springer eBooks · doi:10.1007/978-1-4899-7662-8_14 · Cited by 4 · see citing works

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Omega−3 Polyunsaturated Fatty Acids (PUFAs): Emerging Plant and Microbial Sources, Oxidative Stability, Bioavailability, and Health Benefits—A Review
Saini, R. K., Prasad, P., Sreedhar, R. V., Akhilender Naidu, K., Shang, X., & Keum, Y.-S. (2021) · Antioxidants · doi:10.3390/antiox10101627 · Cited by 337 · see citing works
Valorization of agro-waste into value added products for sustainable development
Dey, T., Bhattacharjee, T., Nag, P., Ritika, R., Ghati, A., & Kuila, A. (2021) · Bioresource Technology Reports · doi:10.1016/j.biteb.2021.100834 · Cited by 157 · see citing works
Nutritional and Functional New Perspectives and Potential Health Benefits of Quinoa and Chia Seeds
Agarwal, A., Rizwana, Tripathi, A. D., Kumar, T., Sharma, K. P., & Patel, S. K. S. (2023) · Antioxidants · doi:10.3390/antiox12071413 · Cited by 135 · see citing works
Chia seeds (<i>Salvia hispanica</i> L.): A therapeutic weapon in metabolic disorders
Khalid, W., Arshad, M. S., Aziz, A., Rahim, M. A., Qaisrani, T. B., Afzal, F., Ali, A., Ranjha, M. M. A. N., Khalid, M. Z., & Anjum, F. M. (2023) · Food Science & Nutrition · doi:10.1002/fsn3.3035 · Cited by 108 · see citing works
Whole or Defatted Sesame Seeds (Sesamum indicum L.)? The Effect of Cold Pressing on Oil and Cake Quality
Melo, D., Álvarez‐Ortí, M., Nunes, M. A., Costa, A. S. G., Machado, S., Alves, R. C., González, J. E. P., & Oliveira, M. B. P. P. (2021) · Foods · doi:10.3390/foods10092108 · Cited by 103 · see citing works
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Integrating Omics and Gene Editing Tools for Rapid Improvement of Traditional Food Plants for Diversified and Sustainable Food Security
Kumar, A., Anju, T., Kumar, S., Chhapekar, S. S., Sreedharan, S., Singh, S., Ramchiary, N., Choi, S. R., & Lim, Y. P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158093 · Cited by 92 · see citing works
Health-promoting approaches of the use of chia seeds
Motyka, S., Skała, E., Ekiert, H., & Szopa, A. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105480 · Cited by 90 · see citing works
Specialty seeds: Nutrients, bioactives, bioavailability, and health benefits: A comprehensive review
Alasalvar, C., Chang, S. K., Bolling, B. W., Oh, W. Y., & Shahidi, F. (2021) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12730 · Cited by 84 · see citing works
New Insights into the Antimicrobial Properties of Hydrolysates and Peptide Fractions Derived from Chia Seed (Salvia hispanica L.)
Aguilar-Toalá, J. E., Deering, A. J., & Liceaga, A. M. (2020) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-020-09653-8 · Cited by 78 · see citing works
The Current State of Knowledge on Salvia hispanica and Salviae hispanicae semen (Chia Seeds)
Motyka, S., Koc, K., Ekiert, H., Blicharska, E., Czarnek, K., & Szopa, A. (2022) · Molecules · doi:10.3390/molecules27041207 · Cited by 58 · see citing works
Chia seed ( Salvia hispanica L.) consumption and lipid profile: a systematic review and meta-analysis
Silva, L. D. A., Verneque, B. J. F., Mota, A. P. L., & Duarte, C. K. (2021) · Food & Function · doi:10.1039/d1fo01287h · Cited by 52 · see citing works
Nutritional and Chemical Characterization of Poppy Seeds, Cold-Pressed Oil, and Cake: Poppy Cake as a High-Fibre and High-Protein Ingredient for Novel Food Production
Melo, D., Álvarez‐Ortí, M., Nunes, M. A., Santo, L. E., Machado, S., González, J. E. P., & Oliveira, M. B. P. P. (2022) · Foods · doi:10.3390/foods11193027 · Cited by 45 · see citing works
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Characterization of Chia Seeds, Cold-Pressed Oil, and Defatted Cake: An Ancient Grain for Modern Food Production
Melo, D., Nunes, M. A., Santo, L. E., Machado, S., Costa, A. S. G., Álvarez‐Ortí, M., González, J. E. P., Oliveira, M. B. P. P., & Alves, R. C. (2023) · Molecules · doi:10.3390/molecules28020723 · Cited by 44 · see citing works
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Salvia hispanica L. (chia) seed promotes body fat depletion and modulates adipocyte lipid handling in sucrose-rich diet-fed rats
Oliva, M. E., Ferreira, M. D. R., Joubert, M. B. V., & D’Alessandro, M. E. (2020) · Food Research International · doi:10.1016/j.foodres.2020.109842 · Cited by 43 · see citing works
Antihypertensive and Antioxidant Activity of Chia Protein Techno-Functional Extensive Hydrolysates
Villanueva-Lazo, A., la Paz, S. M., Rodríguez-Martín, N. M., Millán, F., Sánchez, C. C., Pedroche, J., & Millán-Linares, M. C. (2021) · Foods · doi:10.3390/foods10102297 · Cited by 41 · see citing works
Comparative Analysis of Metabolic Variations, Antioxidant Profiles and Antimicrobial Activity of Salvia hispanica (Chia) Seed, Sprout, Leaf, Flower, Root and Herb Extracts
Motyka, S., Kusznierewicz, B., Ekiert, H., Korona‐Głowniak, I., & Szopa, A. (2023) · Molecules · doi:10.3390/molecules28062728 · Cited by 38 · see citing works
Chia mucilage carrier systems: A review of emulsion, encapsulation, and coating and film strategies
Fernandes, S. S., Cardoso, P. D. S., Egea, M. B., Martínez, J. P. Q., Campos, M. R. S., & Otero, D. M. (2023) · Food Research International · doi:10.1016/j.foodres.2023.113125 · Cited by 38 · see citing works
Influence of the addition of chia seeds and germinated seeds and sprouts on the nutritional and beneficial properties of yogurt
Eker, M. E., & Karakaya, S. (2020) · International Journal of Gastronomy and Food Science · doi:10.1016/j.ijgfs.2020.100276 · Cited by 33 · see citing works
The rising status of edible seeds in lifestyle related diseases: A review
Kakkar, S., Tandon, R., & Tandon, N. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2022.134220 · Cited by 33 · see citing works
Recent industrials extraction of plants seeds oil used in the development of functional food products: A Review
Afzal, M. F., Khalid, W., Khalid, M. A., Zubaır, M., Akram, S., Kauser, S., Noreen, S., Jamal, A., Khan, M. K., & AL-Farga, A. M. (2022) · International Journal of Food Properties · doi:10.1080/10942912.2022.2144882 · Cited by 31 · see citing works
Application of high-pressure homogenization to steer the technological functionalities of chia fibre-protein concentrate
Renoldi, N., Melchior, S., Calligaris, S., & Peressini, D. (2023) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2023.108505 · Cited by 28 · see citing works
Evaluation of Thermal Degradation of Tropane and Opium Alkaloids in Gluten-Free Corn Breadsticks Samples Contaminated with Stramonium Seeds and Baked with Poppy Seeds under Different Conditions
Vera-Baquero, F. L., Morante‐Zarcero, S., & Sierra, I. (2022) · Foods · doi:10.3390/foods11152196 · Cited by 25 · see citing works
Assessment of the Phytochemical and Nutrimental Composition of Dark Chia Seed (Salvia hispánica L.)
Rodríguez‐Lara, A., Mesa, M. D., Medina, K. A. D., Quirantes‐Piné, R., Casuso, R. A., Segura‐Carretero, A., & Huertas, J. R. (2021) · Foods · doi:10.3390/foods10123001 · Cited by 24 · see citing works
Multifunctional Analysis of Chia Seed (Salvia hispanica L.) Bioactive Peptides Using Peptidomics and Molecular Dynamics Simulations Approaches
Aguilar-Toalá, J. E., Limón, A. M. V., & Liceaga, A. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137288 · Cited by 23 · see citing works
Effect of Chia (Salvia hispanica L.) Associated with High-Fat Diet on the Intestinal Health of Wistar Rats
Mishima, M. D. V., Da Silva, B. P., Gomes, M. J. C., Toledo, R. C. L., Mantovani, H. C., José, V. P. B. D. S., Costa, N. M. B., Tako, E., & Martino, H. S. D. (2022) · Nutrients · doi:10.3390/nu14224924 · Cited by 23 · see citing works
Defatted Flaxseed Flour as a New Ingredient for Foodstuffs: Comparative Analysis with Whole Flaxseeds and Updated Composition of Cold-Pressed Oil
Melo, D., Machado, S., Santo, L. E., Nunes, M. A., Costa, A. S. G., Álvarez‐Ortí, M., González, J. E. P., Alves, R. C., & Oliveira, M. B. P. P. (2024) · Nutrients · doi:10.3390/nu16203482 · Cited by 19 · see citing works
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The therapeutic potential of chia seeds as medicinal food: a review
Jeelani, P. G., Sinclair, B. J., Perinbarajan, G. K., Ganesan, H., Ojha, N., Ramalingam, C., Muthuramalingam, P., & Mossa, A.-T. H. (2023) · Nutrire · doi:10.1186/s41110-023-00224-9 · Cited by 17 · see citing works
Multi-omic analyses reveal the unique properties of chia (Salvia hispanica) seed metabolism
Alejo‐Jacuinde, G., Nájera‐González, H., Montes, R. A. C., Reyes, C. D. G., Barragán-Rosillo, A. C., Sanchez, B. P., Mechref, Y. S., López-Arredondo, D. L., Yong‐Villalobos, L., & Herrera‐Estrella, L. (2023) · Communications Biology · doi:10.1038/s42003-023-05192-4 · Cited by 17 · see citing works
β-Carotene biofortification of chia sprouts with plant growth regulators
Bermejo, N. F., Hoummadi, G., & Munné‐Bosch, S. (2021) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2021.10.026 · Cited by 16 · see citing works
α-Linolenic acid rich-chia seed modulates visceral adipose tissue collagen deposition, lipolytic enzymes expression, insulin signaling and GLUT-4 levels in a diet-induced adiposity rodent model
Aiassa, V., Ferreira, M. D. R., Villafañe, N., & D’Alessandro, M. E. (2022) · Food Research International · doi:10.1016/j.foodres.2022.111164 · Cited by 15 · see citing works
Cardioprotective action of chia ( Salvia hispanica L.) in ovariectomized rats fed a high fat diet
Mishima, M. D. V., Ladeira, L., da Silva, B. P., Toledo, R. C. L., de Oliveira, T. V., Costa, N. M. B., & Martino, H. S. D. (2021) · Food & Function · doi:10.1039/d0fo03206a · Cited by 14 · see citing works
Potential effect of Chia Seeds Crude Extract Nanoparticles on Mcf-7 Breast Cancer Cell Line
Shaer, N. A., & Al-Abbas, N. S. (2022) · Al-Azhar International Medical Journal /Al-Azhar International Medical Journal · doi:10.21608/aimj.2022.97818.1585 · Cited by 14 · see citing works
Impact of Defatted Chia Seeds Flour Addition on Chemical, Rheological, and Sensorial Properties of Toast Bread
Nassef, S. L., El-Hadidy, G. S., & Abdelsattar, A. (2023) · Egyptian Journal of Agricultural Sciences /Egyptian Journal of Agricultural Sciences · doi:10.21608/ejarc.2023.174785.1008 · Cited by 13 · see citing works
CSMP: A Self‐Assembled Plant Polysaccharide‐Based Hydrofilm for Enhanced Wound Healing
Qiao, Z., Zhang, K., Liu, H., Roh, Y., Kim, M. G., Lee, H. J., Koo, B., Lee, E. Y., Lee, M., Park, C. O., et al. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202303244 · Cited by 12 · see citing works
Chia seeds oil ameliorate chronic immobilization stress-induced neurodisturbance in rat brains via activation of the antioxidant/anti-inflammatory/antiapoptotic signaling pathways
Khalifa, N. E., Noreldin, A. E., Khafaga, A. F., El-Beskawy, M., Khalifa, E., El‐Far, A. H., Fayed, A.-H. A., & Zakaria, A. (2023) · Scientific Reports · doi:10.1038/s41598-023-49061-w · Cited by 12 · see citing works
Profiling of Lipids, Nutraceuticals, and Bioactive Compounds Extracted from an Oilseed Rich in PUFA
Gopalam, R., Manasa, V., Vaishnav, S. R., Daga, P., & Tumaney, A. W. (2022) · Plant Foods for Human Nutrition · doi:10.1007/s11130-021-00945-0 · Cited by 12 · see citing works
Changes in the Physicochemical Properties of Chia (Salvia hispanica L.) Seeds during Solid-State and Submerged Fermentation and Their Influence on Wheat Bread Quality and Sensory Profile
Bartkienė, E., Rimsa, A., Zokaitytė, E., Starkutė, V., Mockus, E., Černauskas, D., Rocha, J. M., & Klupšaitė, D. (2023) · Foods · doi:10.3390/foods12112093 · Cited by 12 · see citing works
Integrated UHPLC-Q-Exactive-MS/MS metabolomics and network pharmacology to explore the potential mechanism of obesity prevention in Pleurotus eryngii treated with different cooking procedures
Yu, R., Zhou, H., Xiong, M., Chen, J., Wang, S., Xu, W. J., Tian, Y., & Su, L. (2025) · Journal of Future Foods · doi:10.1016/j.jfutfo.2024.08.012 · Cited by 10 · see citing works
Edible seeds with potential anti-obesity impact: A Review
Hosny, H., Omran, N., & Handoussa, H. (2022) · International Journal of Plant Based Pharmaceuticals · doi:10.62313/ijpbp.2022.17 · Cited by 9 · see citing works
Managing Feline Idiopathic Hypercalcemia With Chia Seeds (Salvia hispanica L.): A Case Series
Fantinati, M., & Priymenko, N. (2020) · Frontiers in Veterinary Science · doi:10.3389/fvets.2020.00421 · Cited by 9 · see citing works
Spectroscopic analysis of chia seeds
Mburu, M. W., Paquet‐Durand, O., Hitzmann, B., & Zettel, V. (2021) · Scientific Reports · doi:10.1038/s41598-021-88545-5 · Cited by 9 · see citing works
A review on extraction, functionality and application of chia seeds as a storehouse of bioactive components
Agurla, V., Sharma, M., Pawase, P. A., Shams, R., Ingale, O. S., & Dash, K. K. (2024) · Measurement Food · doi:10.1016/j.meafoo.2024.100185 · Cited by 8 · see citing works
Chemical composition, biological activity and utilization of chia seeds (Salviae hispanicae semen)
Motyka, S., Ekiert, H., & Szopa, A. (2021) · Farmacja Polska · doi:10.32383/farmpol/145400 · Cited by 8 · see citing works
Quality and safety of new types of dairy products based on cow’s and mare’s milk with vegetable additives
Iztileuov, M. К., Ospanov, A., Dikhanbayeva, F., Смаилова, Ж., & Zhunussova, G. (2024) · Food Production Processing and Nutrition · doi:10.1186/s43014-023-00218-0 · Cited by 9 · see citing works
In vitro digestion of whole chia seeds ( Salvia hispanica L.): Nutrient bioaccessibility, structural and functional changes
Han, J., Zhang, Q., Luo, W., Wang, Z., Pang, Y., & Shen, X. (2022) · International Journal of Food Science & Technology · doi:10.1111/ijfs.15698 · Cited by 7 · see citing works
Novel foods, neglected and alien species to increase food biodiversity of diets in Europe
Kalmpourtzidou, Α., Boussetta, S., Al‐Naqeb, G., Giuseppe, R. D., & Cena, H. (2025) · Future Foods · doi:10.1016/j.fufo.2025.100596 · Cited by 6 · see citing works
Salvia hispanica L. (chia) seed have beneficial effects upon visceral adipose tissues extracellular matrix disorders and inflammation developed in a sucrose-rich diet-induced adiposity rodent model
Aiassa, V., Ferreira, M. D. R., Ingaramo, P. I., & D’Alessandro, M. E. (2024) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2024.112438 · Cited by 5 · see citing works
Chia (Salvia hispanica L.) Seeds: Nutritional composition and biomedical applications
Gabal, A. (2024) · Biological and Biomedical Journal · doi:10.21608/bbj.2024.341809 · Cited by 5 · see citing works
Comparative study illustrating the efficacy of novel ultrasonication‐assisted heat treatment over conventional heat treatment in functional smoothie
Kumar, S., Chawla, R., Sivakumar, S., Khatkar, S. K., Kumar, N., & Goel, N. (2023) · International Journal of Food Science & Technology · doi:10.1111/ijfs.16363 · Cited by 4 · see citing works
Prunella vulgaris L. seeds: a promising source of lipids, proteins, and original phenolic compounds presenting high antioxidant and anti-inflammatory activity
Danthine, S., Paul, A., Jansen, O., Ducrey, A., Richel, A., Lognay, G. C., Maesen, P., Kapepula, P. M., Mouithys-Mickalad, A., Franck, T. J., et al. (2021) · BASE · doi:10.25518/1780-4507.19412 · Cited by 4 · see citing works
Salvia hispanica L. (chia seeds) alleviates paracetamol-induced acute liver injury in mice by modulating oxidative stress and inflammation
Ahmed, S. M., & Masoud, M. A. (2024) · Egyptian Pharmaceutical Journal · doi:10.4103/epj.epj_327_23 · Cited by 3 · see citing works
Valorizing Bio-Waste and Residuals
Stefi, A. L., & Vorgias, K. E. (2025) · Advances in biochemical engineering, biotechnology · doi:10.1007/10_2025_278 · Cited by 3 · see citing works
Distinction of chia varieties in vivo and in vitro based on the flow cytometry and rosmarinic acid production
Motyka, S., Szopa, A., & Ochatt, S. (2024) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-024-13171-w · Cited by 3 · see citing works
Study of the modulator effect of oil chia (Salvia hispanica L.) associated with benzo(a)pyrene and doxorubicin hydrochloride
Guterres, Z. R., Lopes, T. F. D. S., de Queiróz, D. F., da Silva, L. M. G. E., & Migliolo, L. (2022) · Research Society and Development · doi:10.33448/rsd-v11i4.27254 · Cited by 3 · see citing works
Chia seed protein: processing, structural and functional properties, and applications in food formulations
Ziaeifar, L., Salami, M., Lai, W., Obireddy, S. R., & Emam‐Djomeh, Z. (2025) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-025-03489-y · Cited by 2 · see citing works
Seed Geometry in Species of the Nepetoideae (Lamiaceae)
del Pozo, D. G., Martín-Gómez, J. J., Tomala, N. I. R., Tocino, Á., & Cervantés, E. (2025) · Horticulturae · doi:10.3390/horticulturae11030315 · Cited by 2 · see citing works
Fontes de luz e composição do meio de cultura no estabelecimento in vitro de chia (Salvia hispanica L.)
Schuelter, A. R., Bellon, C., Canonica, M., Stefanello, S., Grignet, R. D. S., & Pereira, D. R. M. (2020) · Research Society and Development · doi:10.33448/rsd-v9i10.8888 · Cited by 2 · see citing works
Effect of the addition of psyllium (Plantago Ovata Forsk) on the total and bioaccessible concentration of the minerals sodium and potassium in frozen banana pulp
Franco, E. A. N., Chávez, D. W. H., Taniguchi, C. A. K., de Lima, A. B., Bastos, M. D. S. R., & de Melo, N. R. (2021) · Research Society and Development · doi:10.33448/rsd-v10i8.16949 · Cited by 1 · see citing works
Etiology of a Rare Intraglandular Foreign Body in the Parotid Gland
Oz, C., Kapı, E., Erkan, S. O., & Külahçı, Ö. (2022) · Turkish Journal of Plastic Surgery · doi:10.4103/tjps.tjps_12_22 · Cited by 1 · see citing works
The Ameliorating Effects of Salvia hispanica Seeds Ethanolic Extract on Methylprednisolone-Induced Osteoporosis in Female Rabbits
Kadhem, M., Al-Rekabi, F. M. K., & Jassam, S. A. (2023) · The Iraqi Journal of Veterinary Medicine · doi:10.30539/ijvm.v47i1.1495 · Cited by 1 · see citing works
Sustainable Utilization of Poppy Seed Oil By‐Products in Gluten‐Free Cookie Production: Advancing Nutrition via Waste‐Reducing Strategies
Adal, S., Çetintaş, Y., Balaban, M., Çalışır, Ü., & ÜNSAL, T. E. (2025) · Journal of Food Science · doi:10.1111/1750-3841.70580 · Cited by 1 · see citing works
A Comprehensive Review on the Therapeutic Effects of Salvia hispanica L. (Chia) on Metabolic Dysfunction–Associated Fatty Liver Disease: Special Focus on Pathogenesis
Parimi, M., Arefhosseini, S., Tutunchi, H., Arefhosseini, S. R., & Ebrahimi‐Mameghani, M. (2025) · International Journal of Clinical Practice · doi:10.1155/ijcp/8660821 · Cited by 1 · see citing works
Chia ( Salvia Hispanica L.) as a Functional Ingredient to Improve the Nutritional Value of Food Products
Brito, F. O., Zago, L., Vidal, J. D., Beres, C., & Miyahira, R. F. (2025) · Food Reviews International · doi:10.1080/87559129.2025.2588458 · Cited by 1 · see citing works
Dietary Chia Seed Oil Enhances Growth, Immunological Response, and Disease Resistance Against Aeromonas hydrophila in Common Carp (Cyprinus carpio)
Acar, Ü., Kesbiç, O. S., Yapıcı, S., Tezel, R., Bilge, G., Türker, A., Güllü, K., Erol, H. S., Terzi̇, F., Demirci, B., et al. (2025) · Fishes · doi:10.3390/fishes11010018 · Cited by 1 · see citing works
Response surface methodology for extraction of chia seed phenolics and their quantification by LC-MS/MS
Yılmaz, P. K., Çağlayan, M. V., Ertaş, A., & Kolak, U. (2025) · Preparative Biochemistry & Biotechnology · doi:10.1080/10826068.2025.2517275 · Cited by 1 · see citing works
التأثیرات العلاجیة المحتملة لبذور الشیا وعباد الشمس على الفئران التی یتم تغذیتها على غذاء عالی فی الدهون
مصطفى, و. (2021) · مجلة البحوث فی مجالات التربیة النوعیة · doi:10.21608/jedu.2021.59866.1224
ПЕРСПЕКТИВА ВИКОРИСТАННЯ НАСІННЯ ЧІА ЯК ФОРТИФІКАЦІЙНОЇ ДОБАВКИ ДО ХЛІБОБУЛОЧНИХ ВИРОБІВ
Гуменюк, О., Zamai, Z., Волкова, Р. М., Хребтань, О. Б., & Тітенко, В. А. (2021) · Herald of Lviv University of Trade and Economics Technical sciences · doi:10.36477/2522-1221-2021-26-04
Les nouvelles graines, des superaliments ?
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Nyingi, J. W., & Mburu, M. W. (2021) · European Journal of Agriculture and Food Sciences · doi:10.24018/ejfood.2021.3.6.381 · Cited by 16 · see citing works

Authors: Melo, D., Machado, T. B., & Oliveira, M. B. P. P.
Affiliations: Universidade do Porto (PT)
LAQV-REQUIMTE
Corresponding author: Oliveira, M. Beatriz P. P.
ORCID: Melo, Diana
Machado, Thelma B.
Oliveira, M. Beatriz P. P.
Venue: Food & Function
Publisher: Royal Society of Chemistry (RSC)
Published: 2019
Volume: 10
Issue: 6
Pages: 3068-3089
ISSN: 2042-6496 (ISSN-L)
2042-650X
DOI: 10.1039/c9fo00239a
OpenAlex: W2945574325
Cited by: 81
References: 83
Citations by year: 2026: 4 · 2025: 13 · 2024: 7 · 2023: 20 · 2022: 16 · 2021: 16 · 2020: 5
FWCI: 0.83
Type: journal article
Language: en
Open access: closed
Licence: rsc.li/journals-terms-of-use (am, 499 d)
Locations: Food & Function (publishedVersion)
PubMed (publishedVersion)
Funders: Fundação para a Ciência e a Tecnologia (UID/QUI/50006/2019)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Seed and Plant Biochemistry
Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Consumer Attitudes and Food Labeling
Keywords: Salvia hispanica, novel foods, nutritional composition, polyunsaturated fatty acids, alpha-linolenic acid, dietary fiber, proteins, bioactive compounds, antioxidants, quercetin, kaempferol, chlorogenic acid, caffeic acid, gluten-free, celiac disease, anti-inflammatory activity, antidiabetic effect, cardiovascular health, hypertension, functional foods
MeSH terms: Antioxidants, Diet, Fatty Acids, Unsaturated, Humans, Minerals, Nutritive Value, Seeds, Salvia

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Chia seeds: An ancient grain trending in modern human diets

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