The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
The biology of white adipocyte proliferation
Abstract
Summary: Expanded adipose tissue mass increases the risk for many clinical conditions including diabetes, hypertension, coronary atherosclerotic heart disease, and some forms of cancer. Therefore, it is imperative that we understand the mechanisms by which fat pads expand. The enlargement of fat cells during the development of obesity has been previously hypothesized to be a triggering factor for the proliferation of new fat cells. There is now a preponderance of evidence that adipose tissue is a source of growth factors such as IGF‐I, IGF binding proteins, TNFα, angiotensin II, and MCSF that are capable of stimulating proliferation. The relative importance of these autocrine/paracrine factors in the normal control of preadipocyte proliferation is unknown. In addition, the proliferative response of preadipocytes to the paracrine milieu is undoubtedly modulated by neural inputs to fat tissue and/or serum factors. Together, these multiple regulatory controls orchestrate overall and region‐specific adipose tissue cellularity responses associated with the development of hyperplastic obesity. Both in vivo and in vitro studies are needed to understand the complex, interacting physiological mechanisms by which growth of this important organ is regulated.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Hotamisligil, G. S., Arner, P., Caro, J. F., Atkinson, R. L., & Spiegelman, B. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117936 · Cited by 3,543
Insulin-like Growth Factor Binding Protein-1: Recent Findings and New Directions
Lee, P. D. K., Giudice, L. C., Conover, C. A., & Powell, D. R. (1997) · Experimental Biology and Medicine · doi:10.3181/00379727-216-44182 · Cited by 523
Regulation of Adipose Cell Number in Man
Prins, J. B., & O'rahilly, S. (1997) · Clinical Science · doi:10.1042/cs0920003 · Cited by 406
Chemical Composition of Newly Born Mammals
WIDDOWSON, E. M. (1950) · Nature · doi:10.1038/166626a0 · Cited by 305
van Harmelen, V, Elizalde, M., Ariapart, P., Bergstedt-Lindqvist, S., Reynisdottir, S., Hoffstedt, J., Lundkvist, I., Bringman, S., & Arner, P. (2000) · International Journal of Obesity · doi:10.1038/sj.ijo.0801217 · Cited by 114
Cited by
Samuelsson, A.-M., Matthews, P. A., Argenton, M., Christie, M. R., McConnell, J. M., Jansen, E. H. J. M., Piersma, A. H., Ozanne, S. E., Twinn, D. F., Remacle, C., et al. (2008) · Hypertension · doi:10.1161/hypertensionaha.107.101477 · Cited by 923
Murano, I., Barbatelli, G., Parisani, V., Latini, C., Muzzonigro, G., Castellucci, M., & Cinti, S. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m800019-jlr200 · Cited by 726
Obesity and related consequences to ageing
Jura, M., & Kozak, L. P. (2016) · AGE · doi:10.1007/s11357-016-9884-3 · Cited by 473
Very Slow Turnover of β-Cells in Aged Adult Mice
Teta, M., Long, S. Y., Wartschow, L. M., Rankin, M. M., & Kushner, J. A. (2005) · Diabetes · doi:10.2337/diabetes.54.9.2557 · Cited by 465
Sympathetic and sensory innervation of brown adipose tissue
Bartness, T. J., Vaughan, C. H., & Song, C. K. (2010) · International Journal of Obesity · doi:10.1038/ijo.2010.182 · Cited by 459
Self-citationNishimura, S., Manabe, I., Nagasaki, M., Hosoya, Y., Yamashita, H., Fujita, H., Ohsugi, M., Tobe, K., Kadowaki, T., Nagai, R., et al. (2007) · Diabetes · doi:10.2337/db06-1749 · Cited by 440
A Pericellular Collagenase Directs the 3-Dimensional Development of White Adipose Tissue
Chun, T.-H., Hotary, K. B., Sabeh, F., Saltiel, A. R., Allen, E. D., & Weiss, S. J. (2006) · Cell · doi:10.1016/j.cell.2006.02.050 · Cited by 378
Kidd, S., Spaeth, E., Watson, K., Burks, J., Lu, H., Klopp, A., Andreeff, M., & Marini, F. C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030563 · Cited by 371
Zhang, Y., Daquinag, A., Traktuev, D. O., Amaya-Manzanares, F., Simmons, P. J., March, K. L., Pasqualini, R., Arap, W., & Kolonin, M. G. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-3444 · Cited by 331
Adiposity indices and dementia
Gustafson, D. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(06)70526-9 · Cited by 237
Adipocyte differentiation and transdifferentiation: plasticity of the adipose organ.
Cinti, S. (2002) · Journal of Endocrinological Investigation · doi:10.1007/bf03344046 · Cited by 213
The spatiotemporal development of adipose tissue
Han, J., Lee, J.-E., Jin, J., Lim, J. S., Oh, N., Kim, K., Chang, S.-I., Shibuya, M., Kim, H., & Koh, G. Y. (2011) · Development · doi:10.1242/dev.067686 · Cited by 212
Immunologic and endocrine functions of adipose tissue: implications for kidney disease
Zhu, Q., & Scherer, P. E. (2018) · Nature Reviews Nephrology · doi:10.1038/nrneph.2017.157 · Cited by 200
Adipose tissues and thyroid hormones
Obregon, M.-J. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00479 · Cited by 167
Regulation of Lipogenesis by Glucocorticoids and Insulin in Human Adipose Tissue
Gathercole, L. L., Morgan, S. A., Bujalska, I. J., Hauton, D., Stewart, P. M., & Tomlinson, J. W. (2011) · PLoS ONE · doi:10.1371/journal.pone.0026223 · Cited by 150
Regulation of Adipocyte Formation by GLP-1/GLP-1R Signaling
Challa, T. D., Beaton, N., Arnold, M., Rudofsky, G., Langhans, W., & Wolfrum, C. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.310342 · Cited by 149
Rydén, M., & Arner, P. (2007) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2007.01854.x · Cited by 118
Insulin-like growth factor binding protein: a possible marker for the metabolic syndrome?
Ruan, W., & Lai, M. (2010) · Acta Diabetologica · doi:10.1007/s00592-009-0142-3 · Cited by 96
Cernkovich, E. R., Deng, J., Bond, M. C., Combs, T. P., & Harp, J. B. (2008) · Endocrinology · doi:10.1210/en.2007-1148 · Cited by 87
Effects of glucagon-like peptide-1 on the differentiation and metabolism of human adipocytes
El Bekay, R., Coín‐Aragüez, L., Fernández‐García, D., Oliva‐Olivera, W., Bernal‐López, R., Clemente‐Postigo, M., Delgado‐Lista, J., Diaz‐Ruiz, A., Guzman‐Ruiz, R., Vázquez‐Martínez, R., et al. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13481 · Cited by 78
Adipose tissue inflammation and metabolic dysfunction: role of exercise.
(2014) · Europe PMC (PubMed Central) · Cited by 67
In vivo and in vitro bisphenol A exposure effects on adiposity
Desai, M., Ferrini, M. G., Jellyman, J. K., Han, G., & Ross, M. G. (2018) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174418000600 · Cited by 64
Mathematical models of energy homeostasis
Pattaranit, R., & van den Berg, H. A. (2008) · Journal of The Royal Society Interface · doi:10.1098/rsif.2008.0216 · Cited by 61
Keller, E., Chazenbalk, G. D., Aguilera, P., Madrigal, V., Grogan, T., Elashoff, D., Dumesic, D. A., & Abbott, D. H. (2014) · Endocrinology · doi:10.1210/en.2014-1050 · Cited by 60
Monjo, M., Pujol, E., & Roca, P. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00563.2004 · Cited by 52
Xie, P., Zhao, C., Huang, W., Yong, T., Chung, A. C. K., He, K., Chen, X., & Cai, Z. (2019) · Science of The Total Environment · doi:10.1016/j.scitotenv.2018.12.007 · Cited by 28
Metadata
- Authors
- Hausman, D. B., DiGirolamo, M., Bartness, T. J., Hausman, G. J., & Martin, R. J.
- Venue
- Obesity Reviews
- Publisher
- Wiley
- Published
- 2001-11
- Volume
- 2
- Issue
- 4
- Pages
- 239-254
- ISSN
- 1467-7881 (ISSN-L)
- 1467-789X
- OpenAlex
- W1967466043
- Cited by
- 707
- References
- 5
- FWCI
- 5.34
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
