Exercise and Mental Health: Many Reasons to Move

Deslandes, Andréa; Moraes, Helena; Ferreira, Camila; Veiga, Heloisa; Silveira, Heitor; Mouta, Raphael; Pompeu, Fernando A.M.S.; Coutinho, Evandro Silva Freire; Laks, Jerson

doi:10.1159/000223730

Cited by 609Physical Activity and HealthExercise and Physiological ResponsesNeurogenesis and neuroplasticity mechanisms

Exercise and Mental Health: Many Reasons to Move

Deslandes, Andréa, Moraes, Helena, Ferreira, Camila, Veiga, Heloisa, Silveira, Heitor, Mouta, Raphael, Pompeu, Fernando A.M.S., Coutinho, Evandro Silva Freire +1 more·2009·Neuropsychobiology

DOI 10.1159/000223730

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Abstract

The relationship between physical activity and mental health has been widely investigated, and several hypotheses have been formulated about it. Specifically, during the aging process, physical exercise might represent a potential adjunctive treatment for neuropsychiatric disorders and cognitive impairment, helping delay the onset of neurodegenerative processes. Even though exercise itself might act as a stressor, it has been demonstrated that it reduces the harmful effects of other stressors when performed at moderate intensities. Neurotransmitter release, neurotrophic factor and neurogenesis, and cerebral blood flow alteration are some of the concepts involved. In this review, the potential effects of exercise on the aging process and on mental health are discussed, concerning some of the recent findings on animal and human research. The overwhelming evidence present in the literature today suggests that exercise ensures successful brain functioning.

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Compared with aerobic exercise alone, resistance + aerobic exercise can produce complementary neurobiological and other physiological effects.
“In addition, compared with aerobic exercise alone, resistance + aerobic exercise can produce complementary neurobiological and other physiological effects [88].”
From Systematic review and meta-analysis of the effects of exercise on depression in adolescents (2022) · cites this paper as [88]
The increased production of neuromodulatory substances such as anandamide, dopamine, serotonin and endorphins may be associated with decreased anxiety and increased pleasure after intervals of intense stimulation.
“The increased production of neuromodulatory substances such as anandamide, dopamine, serotonin and endorphins may be associated with decreased anxiety and increased pleasure after intervals of intense stimulation [32].”
From Continuous and high-intensity interval training: Which promotes higher pleasure? (2013) · cites this paper as [32]

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Authors: Deslandes, A., Moraes, H., Ferreira, C., Veiga, H., Silveira, H., Mouta, R., Pompeu, F. A. M. S., Coutinho, E. S. F., & Laks, J.
Affiliations: Universidade Federal do Rio de Janeiro (BR)
Escuela Nacional de Sanidad (ES)
ORCID: Deslandes, Andréa
Moraes, Helena
Ferreira, Camila
Pompeu, Fernando A.M.S.
Coutinho, Evandro Silva Freire
Laks, Jerson
Venue: Neuropsychobiology
Publisher: S. Karger AG
Published: 2009
Volume: 59
Issue: 4
Pages: 191-198
ISSN: 0302-282X (ISSN-L)
1423-0224
DOI: 10.1159/000223730
OpenAlex: W2027342527
Cited by: 609
References: 78
Citations by year: 2026: 16 · 2025: 38 · 2024: 42 · 2023: 44 · 2022: 55 · 2021: 52 · 2020: 41 · 2019: 33 · 2018: 32 · 2017: 33 · 2016: 16 · 2015: 45 · 2014: 40 · 2013: 34 · 2012: 25
FWCI: 3.11
Type: journal article
Language: en
Open access: closed
Licence: www.karger.com/Services/SiteLicenses (vor)
www.karger.com/Services/SiteLicenses (tdm)
Locations: Neuropsychobiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology › Physical Activity and Health
Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Keywords: physical activity, mental health, aging, neuropsychiatric disorders, cognitive impairment, neurodegeneration, stress, neurotransmitter release, neurotrophic factors, neurogenesis, cerebral blood flow, brain function
MeSH terms: Alzheimer Disease, Animals, Brain, Major Depressive Disorder, Exercise Therapy, Humans, Mental Health, Models, Neurological, Parkinson Disease, Physical Conditioning, Animal, Exercise

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Exercise and Mental Health: Many Reasons to Move

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