Cytokines, Prostaglandins and Parturition—A Review

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PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

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15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ

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15-Deoxy-Δ 12,14 -prostaglandin J 2 inhibits multiple steps in the NF-κB signaling pathway

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Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

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Endocrine and Paracrine Regulation of Birth at Term and Preterm*

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The Human Placenta

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A review of premature birth and subclinical infection

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SOCS Proteins: Negative Regulators of Cytokine Signaling

Krebs, D. L., & Hilton, D. J. (2001) · STEM CELLS · doi:10.1634/stemcells.19-5-378 · Cited by 827

Interleukin (IL)-10 Inhibits Nuclear Factor кB (NFкB) Activation in Human Monocytes

Wang, P., Wu, P., Siegel, M. I., Egan, R. W., & Billah, M. M. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.16.9558 · Cited by 711

Molecular Identification of Cytosolic Prostaglandin E2 Synthase That Is Functionally Coupled with Cyclooxygenase-1 in Immediate Prostaglandin E2Biosynthesis

Tanioka, T., Nakatani, Y., Semmyo, N., Murakami, M., & Kudo, I. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003504200 · Cited by 708 · cited 1×

Suppressors of cytokine signalling (SOCS) in the immune system

Alexander, W. S. (2002) · Nature Reviews Immunology · doi:10.1038/nri818 · Cited by 645

The Jak-STAT pathway

Imada, K., & Leonard, W. J. (2000) · Molecular Immunology · doi:10.1016/s0161-5890(00)00018-3 · Cited by 610 · cited 1×

The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression.

Gulick, T., Cresci, S., Caira, T., Moore, D. D., & Kelly, D. P. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.23.11012 · Cited by 560

Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide.

Cassatella, M. A., Meda, L., Bonora, S., Ceska, M., & Constantin, G. (1993) · The Journal of experimental medicine · doi:10.1084/jem.178.6.2207 · Cited by 507

Gigantism in mice lacking suppressor of cytokine signalling-2

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Infection in the pathogenesis of preterm labor.

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Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids.

Rodríguez, J. C., Gil-Gómez, G., Hegardt, F. G., & Haro, D. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32234-2 · Cited by 378

15-deoxy Δ^ -PGJ2 inhibits multiple steps in the NF-kappaB signaling pathway

Straus, D. S. (2000) · Medical Entomology and Zoology · Cited by 371

Cytotoxicity of tumour necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts

Yui, J., Garcia-Lloret, M., Wegmann, T. G., & Guilbert, L. J. (1994) · Placenta · doi:10.1016/s0143-4004(05)80184-5 · Cited by 361

Immunolocalization of Proinflammatory Cytokines in Myometrium, Cervix, and Fetal Membranes During Human Parturition at Term1

Young, A., Thomson, A. J., Ledingham, M., Jordan, F., Greer, I. A., & Norman, J. E. (2002) · Biology of Reproduction · doi:10.1095/biolreprod66.2.445 · Cited by 361

Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10.

Roth, I., Corry, D. B., Locksley, R. M., Abrams, J. S., Litton, M. J., & Fisher, S. J. (1996) · The Journal of experimental medicine · doi:10.1084/jem.184.2.539 · Cited by 342

Cytokines of the Placenta and Extra-placental Membranes: Roles and Regulation During Human Pregnancy and Parturition

Bowen, J. M., Chamley, L., Keelan, J. A., & Mitchell, M. D. (2002) · Placenta · doi:10.1053/plac.2001.0782 · Cited by 337

Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthase

Urade, Y., & Hayaishi, O. (2000) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/s0167-4838(00)00161-8 · Cited by 332

Gestational Age-Dependent Expression of IL-10 and Its Receptor in Human Placental Tissues and Isolated Cytotrophoblasts

Hanna, N., Hanna, I., Hleb, M., Wagner, E., Dougherty, J., Balkundi, D., Padbury, J., & Sharma, S. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.11.5721 · Cited by 313

PATHOGENESIS OF PRETERM LABOR AND PRETERM PREMATURE RUPTURE OF MEMBRANES ASSOCIATED WITH INTRAAMNIOTIC INFECTION

Gomez, R., Romero, R., Edwin, S. S., & David, C. (1997) · Infectious Disease Clinics of North America · doi:10.1016/s0891-5520(05)70347-0 · Cited by 312

Human labour is associated with nuclear factor-kappaB activity which mediates cyclo-oxygenase-2 expression and is involved with the 'functional progesterone withdrawal'

Allport, V. C. (2001) · Molecular Human Reproduction · doi:10.1093/molehr/7.6.581 · Cited by 307

Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

Roberts, A. W., Robb, L., Rakar, S., Hartley, L., Cluse, L., Nicola, N. A., Metcalf, D., Hilton, D. J., & Alexander, W. S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.161271798 · Cited by 300

The prevalence and distribution of acute placental inflammation in uncomplicated term pregnancies

Salafia, C., Weigi, C., & Silberman, L. (1989) · International Journal of Gynecology & Obstetrics · doi:10.1016/0020-7292(89)90252-x · Cited by 296

Interlukin-1 stimulates prostaglandin biosynthesis by human amnion

Romero, R., Durum, S., Dinarello, C. A., Oyarzun, E., Hobbins, J. C., & Mitchell, M. D. (1989) · Prostaglandins · doi:10.1016/0090-6980(89)90028-2 · Cited by 295

Cytokines of the Placenta and Extra-placental Membranes: Biosynthesis, Secretion and Roles in Establishment of Pregnancy in Women

Bowen, J. M., Chamley, L., Mitchell, M. D., & Keelan, J. A. (2002) · Placenta · doi:10.1053/plac.2001.0781 · Cited by 239

Prostaglandin E synthase

Murakami, M., Nakatani, Y., Tanioka, T., & Kudo, I. (2002) · Prostaglandins & Other Lipid Mediators · doi:10.1016/s0090-6980(02)00043-6 · Cited by 232

Interleukin-6 stimulates prostaglandin production by human amnion and decidual cells.

Mitchell, M. D., Dudley, D. J., Edwin, S. S., & Schiller, S. L. (1991) · European Journal of Pharmacology · doi:10.1016/0014-2999(91)90090-d · Cited by 228

A role for matrix metalloproteinase-9 in spontaneous rupture of the fetal membranes

Athayde, N., Edwin, S. S., Romero, R., Gomez, R., Maymon, E., Pacora, P., & Menon, R. (1998) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(98)70141-3 · Cited by 224

Interleukin-8 Synthesis and the Onset of Labor

Osmers, R. (1995) · Obstetrics & Gynecology · doi:10.1016/0029-7844(95)93704-4 · Cited by 224

Prostaglandin E Synthase

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A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist

Xu, W., Presnell, S. R., Parrish-Novak, J., Kindsvogel, W., Jaspers, S., Chen, Z., Dillon, S. R., Gao, Z., Gilbert, T., Madden, K., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.171303198 · Cited by 212

Prostaglandin biosynthesis by human decidual cells: Effects of inflammatory mediators

Mitchell, M. D., Edwin, S., & Romero, R. J. (1990) · Prostaglandins, Leukotrienes and Essential Fatty Acids · doi:10.1016/0952-3278(90)90128-8 · Cited by 199

Elevation of amniotic fluid interleukin 6 (IL-6), IL-8 and granulocyte colony stimulating factor (G-CSF) in term and preterm parturition

Saito, S., Kasahara, T., Kato, Y., Ishihara, Y., & Ichijo, M. (1993) · Cytokine · doi:10.1016/1043-4666(93)90027-3 · Cited by 189

The role of prostaglandins in human parturition

Gibb, W. (1998) · Annals of Medicine · doi:10.3109/07853899809005850 · Cited by 189

Biological activities and mechanisms of action of PGJ2 and related compounds: an update

Fukushima, M. (1992) · Prostaglandins, Leukotrienes and Essential Fatty Acids · doi:10.1016/0952-3278(92)90178-l · Cited by 186

The Transforming Growth Factor-β Superfamily Cytokine Macrophage Inhibitory Cytokine-1 Is Present in High Concentrations in the Serum of Pregnant Women1

Moore, A. G., Brown, D. A., Fairlie, W. D., Bauskin, A. R., Brown, P. K., Munier, M. L. C., Russell, P. K., Salamonsen, L. A., Wallace, E. M., & Breit, S. N. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.12.7007 · Cited by 180

Increased matrix metalloproteinase activity and reduced tissue inhibitor of metalloproteinases-1 levels in amniotic fluids from pregnancies complicated by premature rupture of membranes

Vadillo-Ortega, F., Hernandez, A., Gonzalez-Avila, G., Bermejo, L., Iwata, K., & Strauss, J. F. (1996) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(96)70687-7 · Cited by 171

Expression of cyclooxygenase types 1 and 2 in human fetal membranes at term

Slater, D. M., Berger, L. C., Newton, R., Moore, G. E., & Bennett, P. R. (1995) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(95)90087-x · Cited by 162

The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo

Zhang, J., Metcalf, D., Rakar, S., Asimakis, M., Greenhalgh, C. J., Willson, T. A., Starr, R., Nicholson, S. E., Carter, W., Alexander, W. S., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.231486498 · Cited by 156

Programmed cell death (apoptosis) as a possible pathway to metalloproteinase activation and fetal membrane degradation in premature rupture of membranes

Fortunato, S. J., Menon, R., Bryant, C., & Lombardi, S. J. (2000) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2000.107330 · Cited by 148

Apoptosis and Fas Expression in Human Fetal Membranes

RUNIC, R., Lockwood, C. J., LaChapelle, L., Dipasquale, B., Demopoulos, R. I., Kumar, A. R., & Guller, S. M. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.2.4600 · Cited by 147

Prostaglandin J2--anti-tumour and anti-viral activities and the mechanisms involved.

Fukushima, M. (1990) · PubMed · Cited by 146

Immunohistochemical localization, messenger ribonucleic acid abundance, and activity of 15-hydroxyprostaglandin dehydrogenase in placenta and fetal membranes during term and preterm labor

Sangha, R., Walton, J. C., Ensor, M., Tai, H., & Challis, J. R. G. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.78.4.8157731 · Cited by 146

Effects of tumour necrosis factor-alpha, interleukin-1 alpha, macrophage colony stimulating factor and transforming growth factor on trophoblastic matrix metalloproteinases

Meisser, A. (1999) · Molecular Human Reproduction · doi:10.1093/molehr/5.3.252 · Cited by 146

Cytokine secretion by human fetal membranes, decidua and placenta at term

Denison, F. C., KELLY, R. W., Calder, A. A., & Riley, S. C. (1998) · Human Reproduction · doi:10.1093/humrep/13.12.3560 · Cited by 140

The action of prostaglandin E2 on the human cervix: Stimulation of interleukin 8 and inhibition of secretory leukocyte protease inhibitor

Denison, F. C., Calder, A. A., & Kelly, R. W. (1999) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(99)70263-2 · Cited by 137

Prostaglandins and parturition

Mitchell, M. D., Romero, R. J., Edwin, S. S., & Trautman, M. S. (1995) · Reproduction Fertility and Development · doi:10.1071/rd9950623 · Cited by 137

Lipopolysaccharide‐induced interleukin‐10 in mice: role of endogenous tumor necrosis factor‐α

Barsig, J., Küsters, S., Vogt, K., Volk, H., Tiegs, G., & Wendel, A. (1995) · European Journal of Immunology · doi:10.1002/eji.1830251027 · Cited by 135

Pre-term labor: an intra-uterine inflammatory response syndrome?

Dudley, D. J. (1997) · Journal of Reproductive Immunology · doi:10.1016/s0165-0378(97)00065-x · Cited by 135

The natural interleukin-1 receptor antagonist in tem and preterm parturition

Romero, R. J., Sepúlveda, W., Mazor, M., Brandt, F., Cotton, D. B., Dinarello, C. A., & Mitchell, M. D. (1992) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(12)80003-2 · Cited by 129

Interleukin-6 concentrations in cervical secretions identify microbial invasion of the amniotic cavity in patients with preterm labor and intact membranes

Rizzo, G., Capponi, A., Rinaldo, D., Tedeschi, D., Arduini, D., & Romaninï, C. (1996) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(96)80004-4 · Cited by 125

Control of human parturition

Olson, D. M., Mijovic, J. E., & Sadowsky, D. W. (1995) · Seminars in Perinatology · doi:10.1016/s0146-0005(95)80047-6 · Cited by 122

Human glutathione dependent prostaglandin E synthase: gene structure and regulation

Forsberg, L. M., Leeb, L., Thorén, S., Morgenstern, R., & Jakobsson, P. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01367-3 · Cited by 121

Interleukin‐1 Stimulates Human Uterine Prostaglandin Production Through Induction of Cyclooxygenase‐2 Expression

Rauk, P. N., & Chiao, J. (2000) · American Journal of Reproductive Immunology · doi:10.1111/j.8755-8920.2000.430304.x · Cited by 118

Endocrinology and Paracrinology

Runesson, E., Boström, E.-K., Janson, P. O., & Brännström, M. (1996) · Molecular Human Reproduction · doi:10.1093/molehr/2.4.245 · Cited by 115

Use of cDNA arrays to generate differential expression profiles for inflammatory genes in human gestational membranes delivered at term and preterm

Marvin, K. W. (2002) · Molecular Human Reproduction · doi:10.1093/molehr/8.4.399 · Cited by 115

Detection of tumor necrosis factor-α, interleukin-6, and fetal fibronectin in the lower genital tract during pregnancy: Relation to outcome

Inglis, S. R., Jeremias, J., Kuno, K., Lescale, K. B., Peeper, Q., Chervenak, F. A., & Witkin, S. S. (1994) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(94)70069-9 · Cited by 114

Amniotic fluid interleukin-10 concentrations increase through pregnancy and are elevated in patients with preterm labor associated with intrauterine infection

Greig, P. C., Herbert, W. N. P., Robinette, B. L., & Teot, L. A. (1995) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(95)91358-0 · Cited by 113

Critical Paracrine Interactions Between TNF-α and IL-10 Regulate Lipopolysaccharide-Stimulated Human Choriodecidual Cytokine and Prostaglandin E2 Production

Sato, T. A., Keelan, J. A., & Mitchell, M. D. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.1.158 · Cited by 113

15-Deoxy-Δ12,14-prostaglandin J2, a Ligand for Peroxisome Proliferator-Activated Receptor-γ, Induces Apoptosis in JEG3 Choriocarcinoma Cells

Keelan, J. A., Sato, T. A., Marvin, K. W., Lander, J., Gilmour, R. S., & Mitchell, M. D. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1257 · Cited by 112

Interleukin-10 Administration and Bacterial Endotoxin-Induced Preterm Birth in a Rat Model

Terrone, D. A., Rinehart, B. K., Granger, J. P., Barrilleaux, P. S., Martin, J. N., & Bennett, W. A. (2001) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(01)01424-7 · Cited by 111

Control of peripartal collagenolysis in the human chorion-decidua

Bryant‐Greenwood, G. D., & Mamamoto, S. Y. (1995) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(95)90085-3 · Cited by 109

Prostaglandin endoperoxide-H synthase (PGHS) activity and immunoreactive PGHS-1 and PGHS-2 levels in human amnion throughout gestation, at term, and during labor

Teixeira, F. J., Zakár, T., Hirst, J. J., Guo, F., Sadowsky, D. W., Machin, G. A., Demianczuk, N. N., Resch, B. A., & Olson, D. M. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.78.6.1396 · Cited by 109

Interleukin-8 is a mediator of the final cervical ripening in humans

Sennström, M., Brauner, A., Lü, Y., et al. (1997) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/s0301-2115(97)02757-7 · Cited by 108

Interleukin 6 enhances the production of tissue inhibitor of metalloproteinases (TIMP) but not that of matrix metalloproteinases by human fibroblats

Sato, T., Itô, A., & Mori, Y. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)92165-v · Cited by 108

Cyclooxygenases in Reproductive Medicine and Biology

Kniss, D. A. (1999) · Journal of the Society for Gynecologic Investigation · doi:10.1016/s1071-5576(99)00034-9 · Cited by 108

Structure and chromosomal localization of human and mouse genes for hematopoietic prostaglandin D synthase

Kanaoka, Y., Fujimori, K., Kikuno, R. F., Sakaguchi, Y., Urade, Y., & Hayaishi, O. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01362.x · Cited by 106

Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1)

Metcalf, D., Mifsud, S., Rago, L. D., Nicola, N. A., Hilton, D. J., & Alexander, W. S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022628499 · Cited by 104

Interleukin-1β and interleukin-8 in cervicovaginal fluid during pregnancy

Tanaka, Y., Narahara, H., Takai, N., Yoshimatsu, J., Anai, T., & Miyakawa, I. (1998) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(98)70058-4 · Cited by 103

Human Placenta Constitutively Produces Interleukin-8 during Pregnancy and Enhances its Production in Intrauterine Infection1

Shimoya, K., Matsuzaki, N., Taniguchi, T., Kameda, T., Koyama, M., Neki, R., Saji, F., & Tanizawa, O. (1992) · Biology of Reproduction · doi:10.1095/biolreprod47.2.220 · Cited by 103

Tumor necrosis factor bifunctionally regulates matrix metalloproteinases and tissue inhibitor of metalloproteinases (TIMP) production by human fibroblasts

Ito, A., Sato, T., Iga, T., & Mori, Y. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)81127-a · Cited by 100

Labor-Associated Changes in Interleukin-10 Production and Its Regulation by Immunomodulators in Human Choriodecidua

Simpson, K. L., Keelan, J. A., & Mitchell, M. D. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.12.5335 · Cited by 94

Elevated protease activities in human amnion and chorion correlate with preterm premature rupture of membranes

Draper, D. L., McGregor, J., Hall, J., Jones, W., Beutz, M. A., Heine, R. P., & Porreco, R. P. (1995) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(95)90640-1 · Cited by 91

Interleukin 16 in pregnancy, parturition, rupture of fetal membranes, and microbial invasion of the amniotic cavity

Athayde, N., Romero, R. J., Maymon, E., et al. (2000) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(00)70502-3 · Cited by 90

A role for the novel cytokine RANTES in pregnancy and parturition

Athayde, N., Romero, R. J., Maymon, E., et al. (1999) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(99)70337-6 · Cited by 89

Matrix metalloproteinase (MMP)-2 and MMP-9 and their inhibitor, TIMP-1, in human term decidua and fetal membranes: the effect of prostaglandin F2alpha and indomethacin

Uluğ, U., Goldman, S., Ben-Shlomo, I., & Shalev, E. (2001) · Molecular Human Reproduction · doi:10.1093/molehr/7.12.1187 · Cited by 89

Immunoreactive 15-hydroxyprostaglandin dehydrogenase (PGDH) is reduced in fetal membranes from patients at preterm delivery in the presence of infection

van Meir, C. A., Sangha, R., Walton, J. C., Matthews, S. G., Keirse, M. J. N. C., & Challis, J. R. G. (1996) · Placenta · doi:10.1016/s0143-4004(96)90052-1 · Cited by 87

Interleukin-1 beta, -1 alpha, and -6 and prostaglandins in vaginal/cervical fluids of pregnant women before and during labor

Cox, S. M., King, M. R., Casey, M. L., & MacDonald, P. C. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.77.3.8370702 · Cited by 87

Biochemical Events in Cervical Ripening Dilatation during Pregnancy and Parturition

Osmers, R., Adelmann‐Grill, B. C., Rath, W. H., et al. (1995) · Journal of Obstetrics and Gynaecology · doi:10.1111/j.1447-0756.1995.tb01092.x · Cited by 87

The relationship between spontaneous rupture of membranes, labor, and microbial invasion of the amniotic cavity and amniotic fluid concentrations of prostaglandins and thromboxane B2 in term pregnancy

Romero, R. J., Baumann, P. A., Gómez, R., et al. (1993) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(93)90675-9 · Cited by 86

The Cervix in pregnancy and labour : clinical and biochemical investigations

Ellwood, D. A., & Anderson, A. B. M. (1981) · Churchill Livingstone eBooks · Cited by 83

Identification of matrix metalloproteinase-9 in amniotic fluid and amniochorion in spontaneous labor and after experimental intrauterine infection or interleukin-1β infusion in pregnant rhesus monkeys

Vadillo‐Ortega, F., Sadowsky, D. W., Haluska, G. J., Hernandez-Guerrero, C., Guevara-Silva, R., Gravett, M. G., & Novy, M. J. (2002) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2002.118916 · Cited by 82

Regulation of Proinflammatory Cytokines in Human Gestational Tissues by Peroxisome Proliferator-Activated Receptor-γ: Effect of 15-Deoxy-Δ12,14-PGJ2and Troglitazone

Lappas, M., Permezel, M., Georgiou, H. M., & Rice, G. E. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020613 · Cited by 82

Interleukin-10 Modifies the Effects of Interleukin-1 and Tumor Necrosis Factor- on the Activity and Expression of Prostaglandin H Synthase-2 and the NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase in Cultured Term Human Villous Trophoblast and Chorion Trophoblast Cells

Pomini, F., Caruso, A., & Challis, J. R. G. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.12.6188 · Cited by 79

Intrauterine infection and the effects of inflammatory mediators on prostaglandin production by myometrial cells from pregnant women

Pollard, J. K., & Mitchell, M. D. (1996) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(96)70450-7 · Cited by 78

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