Improvement of Cognitive Function by Mental and/or Individualized Aerobic Training in Healthy Elderly Subjects
Abstract
The aim of this study was to compare the effects of aerobic and mental training on cognitive function and to determine if the association of the two techniques shows better results. Thirty-two healthy elderly subjects (60 - 76 years) were assigned to one of four groups: aerobic training, mental training, combined aerobic and mental training and a control group. All subjects took two cognitive tests and an incremental exercise test before and after the training period. The intensity of exercise was individualized at the heart rate corresponding to the ventilatory threshold of each subject. After two months, the control group showed no alteration in physiological and cognitive variables. After the training period, the results showed a significant improvement in VO(2)max (F = 4.45, DF = 1, p < 0.05) of 12 % and 11 % in aerobic training and combined aerobic and mental training groups, respectively. Logical memory (F = 4.31, DF = 1, p < 0.05), as well as paired associates learning scores (F = 5.47, DF = 1, p < 0.05) and memory quotient (F = 6.52, DF = 1, p < 0.01) were significantly improved in the three trained groups. The mean difference in memory quotient between pre and post training was significantly higher in the combined aerobic and mental training group compared to aerobic training or mental training groups (F = 11.60, DF = 3, p < 0.001). We conclude that the specific aerobic training and mental training used in this study could induce the same degree of improvement in cog…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In Fabre et al. (2002), benefits were largest for the combined-training group.
“However, in this experiment, benefits were largest for the combined-training group.”
From Enrichment Effects on Adult Cognitive Development: Can the Functional Capacity of Older Adults Be Preserved and Enhanced? (2008) · cites this paper as Fabre, Charmi, Mucci, Masse-Biron, and Prefaut (2002)
Fabre et al. (2002) found improvements in a general memory metric in all three training groups.
“Results indicated improvements in a general memory metric in all three of the training groups.”
From Enrichment Effects on Adult Cognitive Development: Can the Functional Capacity of Older Adults Be Preserved and Enhanced? (2008) · cites this paper as Fabre, Charmi, Mucci, Masse-Biron, and Prefaut (2002)
Cited by
Sorted by citations
Exercise and Physical Activity for Older Adults
Chodzko-Zajko, W. J., Proctor, D. N., Fiatarone Singh, M. A., Minson, C. T., Nigg, C. R., Salem, G. J., & Skinner, J. S. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181a0c95c · Cited by 5,153 · see citing works
Smith, P. J., Blumenthal, J. A., Hoffman, B. M., Cooper, H., Strauman, T. A., Welsh-Bohmer, K., Browndyke, J. N., & Sherwood, A. (2010) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181d14633 · Cited by 1,714 · see citing works
Epidemiology of Alzheimer disease
Reitz, C., Brayne, C., & Mayeux, R. (2011) · Nature Reviews Neurology · doi:10.1038/nrneurol.2011.2 · Cited by 1,675 · see citing works
Hertzog, C., Kramer, A. F., Wilson, R. S., & Lindenberger, U. (2008) · Psychological Science in the Public Interest · doi:10.1111/j.1539-6053.2009.01034.x · Cited by 1,495 · see citing works
Northey, J. M., Cherbuin, N., Pumpa, K. L., Smee, D. J., & Rattray, B. (2018) · British Journal of Sports Medicine · doi:10.1136/bjsports-2016-096587 · Cited by 1,380 · see citing works
Angevaren, M., Aufdemkampe, G., Verhaar, H., Aleman, A., & Vanhees, L. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005381.pub3 · Cited by 1,130 · see citing works
Beneficial effects of physical exercise on neuroplasticity and cognition
Hötting, K., & Röder, B. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.04.005 · Cited by 991 · see citing works
Paterson, D. H., & Warburton, D. E. (2010) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/1479-5868-7-38 · Cited by 953 · see citing works
Brain metabolism in health, aging, and neurodegeneration
Camandola, S., & Mattson, M. P. (2017) · The EMBO Journal · doi:10.15252/embj.201695810 · Cited by 752 · see citing works
A meta-regression to examine the relationship between aerobic fitness and cognitive performance
Etnier, J. L., Nowell, P. M., Landers, D. M., & Sibley, B. A. (2006) · Brain Research Reviews · doi:10.1016/j.brainresrev.2006.01.002 · Cited by 749 · see citing works
Exercise, cognition, and the aging brain
Kramer, A. F., Erickson, K. I., & Colcombe, S. J. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00500.2006 · Cited by 719 · see citing works
Aerobic exercise to improve cognitive function in older people without known cognitive impairment
Young, J., Angevaren, M., Rusted, J., & Tabet, N. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005381.pub4 · Cited by 505 · see citing works
The effects of cardiovascular exercise on human memory: a review with meta-analysis
Roig, M., Nordbrandt, S., Geertsen, S. S., & Nielsen, J. B. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.06.012 · Cited by 460 · see citing works
Exergaming and Older Adult Cognition
Anderson-Hanley, C., Arciero, P. J., Brickman, A. M., Nimon, J. P., Okuma, N., Westen, S. C., Merz, M. E., Pence, B. D., Woods, J. A., Kramer, A. F., et al. (2012) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2011.10.016 · Cited by 464 · see citing works
Fiatarone Singh, M. A., Gates, N., Saigal, N., Wilson, G. C., Meiklejohn, J., Brodaty, H., Wen, W., Singh, N., Baune, B. T., Suo, C., et al. (2014) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2014.09.010 · Cited by 424 · see citing works
Physical activity, brain, and cognition
Erickson, K. I., Hillman, C. H., & Kramer, A. F. (2015) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2015.01.005 · Cited by 406 · see citing works
Pesce, C. (2012) · Journal of Sport and Exercise Psychology · doi:10.1123/jsep.34.6.766 · Cited by 383 · see citing works
Gavelin, H. M., Dong, C., Minkov, R., Bahar-Fuchs, A., Ellis, K. A., Lautenschlager, N. T., Mellow, M. L., Wade, A. T., Smith, A. E., Finke, C., et al. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101232 · Cited by 371 · see citing works
Physical activity and Alzheimer's disease: from prevention to therapeutic perspectives
Rolland, Y., Abellan van Kan, G., & Vellas, B. (2008) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2008.02.007 · Cited by 312 · see citing works
Physical activity in relation to cognitive decline in elderly men: The FINE Study
van Gelder, B. M., Tijhuis, M. A. R., Kalmijn, S., Giampaoli, S., Nissinen, A., & Kromhout, D. (2004) · Neurology · doi:10.1212/01.wnl.0000147474.29994.35 · Cited by 311 · see citing works
Uffelen, J. G. Z. V., Chin A Paw, M. J. M., Hopman-Rock, M., & Mechelen, W. V. (2008) · Clinical Journal of Sport Medicine · doi:10.1097/jsm.0b013e3181845f0b · Cited by 296 · see citing works
Physical and Cognitive Activity and Exercise for Older Adults: A Review
Hogan, M. (2005) · The International Journal of Aging and Human Development · doi:10.2190/ptg9-xdvm-yeta-mkxa · Cited by 156 · see citing works
The effects of physical exercise and cognitive training on memory and neurotrophic factors.
Heisz, J. J., Clark, I. B., Bonin, K., Paolucci, E. M., Michalski, B., Becker, S., & Fahnestock, M. (2017) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01164 · Cited by 144 · see citing works
Steffener, J., Reuben, A., Rakitin, B. C., & Stern, Y. (2011) · Brain Imaging and Behavior · doi:10.1007/s11682-011-9125-4 · Cited by 113 · see citing works
Healthy Brain Aging: Role of Exercise and Physical Activity
Rolland, Y., Abellan van Kan, G., & Vellas, B. (2010) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2009.11.002 · Cited by 103 · see citing works
Shah, T., Verdile, G., Sohrabi, H., Campbell, A., Putland, E., Cheetham, C., Dhaliwal, S., Weinborn, M., Maruff, P., Darby, D., et al. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.122 · Cited by 94 · see citing works
Brun, J.-F., Romain, A.-J., & Mercier, J. (2011) · Science & Sports · doi:10.1016/j.scispo.2011.02.001 · Cited by 60 · see citing works
Intervention-induced enhancement in intrinsic brain activity in healthy older adults
Yin, S., Zhu, X., Li, R., Niu, Y., Wang, B., Zheng, Z., Huang, X., Huo, L., & Li, J. (2014) · Scientific Reports · doi:10.1038/srep07309 · Cited by 57 · see citing works
Gates, N. J., Rutjes, A. W., Di Nisio, M., Karim, S., Chong, L.-Y., March, E., Martínez, G., & Vernooij, R. W. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012278.pub2 · Cited by 46 · see citing works
Effects of Endurance-Focused Physical Activity Interventions on Brain Health: A Systematic Review
Halloway, S., Wilbur, J., Schoeny, M. E., & Arfanakis, K. (2017) · Biological Research For Nursing · doi:10.1177/1099800416660758 · Cited by 31 · see citing works
Bae, S., Harada, K., Lee, S., Harada, K., Makino, K., Chiba, I., Park, H., & Shimada, H. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9051312 · Cited by 29 · see citing works
Palomo, T., Beninger, R. J., Kostrzewa, R. M., & Archer, T. (2008) · Neurotoxicity Research · doi:10.1007/bf03033807 · Cited by 28 · see citing works
Brun, J.-F., Varlet-Marie, E., Jrme, A., & Mercier, J. (2012) · An International Perspective on Topics in Sports Medicine and Sports Injury · doi:10.5772/25451 · Cited by 19 · see citing works
Han, H., Zhang, J., Zhang, F., Li, F., & Wu, Z. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1510773 · Cited by 21 · see citing works
- Authors
- Fabre, C., Chamari, K., Mucci, P., Massé-Biron, J., & Préfaut, C.
- Affiliations
- Université de Lille (FR)
- Qatar Orthopaedic and Sports Medicine Hospital (QA)
- Venue
- International Journal of Sports Medicine
- Publisher
- Georg Thieme Verlag KG
- Published
- 2002-08
- Volume
- 23
- Issue
- 6
- Pages
- 415-421
- ISSN
- 0172-4622 (ISSN-L)
- 1439-3964
- OpenAlex
- W1977466344
- Cited by
- 416
- References
- 0
- Citations by year
- 2026: 10 · 2025: 10 · 2024: 7 · 2023: 16 · 2022: 25 · 2021: 14 · 2020: 24 · 2019: 18 · 2018: 19 · 2017: 40 · 2016: 24 · 2015: 31 · 2014: 27 · 2013: 29 · 2012: 17
- FWCI
- 13.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Sports Medicine (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- LillOA (Université de Lille (University Of Lille)) (submittedVersion)
- Funders
- Université de Montpellier
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- aerobic exercise, mental training, cognitive function, older adults, concurrent training, memory, logical memory, paired-associate learning, memory quotient, ventilatory threshold, heart rate, VO2max, exercise training
- MeSH terms
- Aged, Aging, Cognition, Humans, Middle Aged, Physical Education and Training, Exercise
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review