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Involutional Osteoporosis
Abstract
OSTEOPOROSIS is an enormous public health problem, responsible for at least 1.2 million fractures in the United States each year. The sites of these fractures are the vertebrae in 538,000 cases, the hip in 227,000, the distal forearm (Colles' fracture) in 172,000, and other limb sites in 283,0001 (and Melton LJ, Riggs BL: unpublished data). One third of women over 65 will have vertebral fractures (Melton LJ, Riggs BL: unpublished data). By extreme old age, one of every three women and one of every six men will have had a hip fracture.2 This catastrophic type of fracture is fatal in . . .
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Cites
Prevention of spinal osteoporosis in oophorectomised women
Lindsay, R., Hart, D. M., Forrest, C., & Baird, C. (1980) · The Lancet · doi:10.1016/s0140-6736(80)92592-1 · Cited by 706
Daniell (1976) · doi:10.1001/archinte.1976.03630030032007 · Cited by 301
Quantum concept of bone remodeling and turnover: Implications for the pathogenesis of osteoporosis
Parfitt, A. M. (1979) · Calcified Tissue International · doi:10.1007/bf02441211 · Cited by 275
Cited by
Human Aging: Usual and Successful
Rowe, J. W., & Kahn, R. L. (1987) · Science · doi:10.1126/science.3299702 · Cited by 3,384
LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye Development
Gong, Y., Slee, R. B., Fukai, N., Rawadi, G., Roman-Roman, S., Reginato, A. M., Wang, H., Cundy, T., Glorieux, F. H., Lev, D., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00571-2 · Cited by 2,235
Leptin Inhibits Bone Formation through a Hypothalamic Relay
Ducy, P., Amling, M., Takeda, S., Priemel, M., Schilling, A. F., Beil, F. T., Shen, J., Vinson, C., Rueger, J. M., & Karsenty, G. (2000) · Cell · doi:10.1016/s0092-8674(00)81558-5 · Cited by 2,077
Sex Steroids and the Construction and Conservation of the Adult Skeleton
Riggs, B. L., Khosla, S., & Melton, L. J. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.3.0465 · Cited by 1,846
Self-citationThe Medical Review Article: State of the Science
MULROW, C. D. (1987) · Annals of Internal Medicine · doi:10.7326/0003-4819-106-3-485 · Cited by 856
Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction.
Tatsumi, S., Ishii, K., Amizuka, N., Li, M., Kobayashi, T., Kohno, K., Ito, M., Takeshita, S., & Ikeda, K. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.05.001 · Cited by 848
Soft Drink Consumption Among US Children and Adolescents
HARNACK, L., STANG, J., & STORY, M. (1999) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(99)00106-6 · Cited by 777
OSTEOIMMUNOLOGY: Interplay Between the Immune System and Bone Metabolism
Walsh, M. C., Kim, N., Kadono, Y., Rho, J., Lee, S. Y., Lorenzo, J., & Choi, Y. (2006) · Annual Review of Immunology · doi:10.1146/annurev.immunol.24.021605.090646 · Cited by 724
How Many Women Have Osteoporosis?
Melton, L. J., Chrischilles, E. A., Cooper, C., Lane, A. W., & Riggs, B. L. (2005) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2005.20.5.886 · Cited by 708
Self-citationTucker, K. L., Hannan, M. T., Chen, H., Cupples, L. A., Wilson, P. W., & Kiel, D. P. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.4.727 · Cited by 705
Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics
Li, J.-Y., Chassaing, B., Tyagi, A. M., Vaccaro, C., Luo, T., Adams, J., Darby, T. M., Weitzmann, M. N., Mulle, J. G., Gewirtz, A. T., et al. (2016) · Journal of Clinical Investigation · doi:10.1172/jci86062 · Cited by 643
The contribution of bone to whole-organism physiology
Karsenty, G., & Ferron, M. (2012) · Nature · doi:10.1038/nature10763 · Cited by 537
Cooper, C., & Melton, L. J. (1992) · Trends in Endocrinology & Metabolism · doi:10.1016/1043-2760(92)90032-v · Cited by 405
Self-citationAvian osteoclasts as estrogen target cells.
Oursler, M. J., Osdoby, P., Pyfferoen, J., Riggs, B. L., & Spelsberg, T. C. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.15.6613 · Cited by 395
Self-citationPathophysiology of Age-Related Bone Loss and Osteoporosis
Khosla, S., & Riggs, B. L. (2005) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2005.07.009 · Cited by 376
Self-citationLarsen, E. R., Mosekilde, L., & Foldspang, A. (2004) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.0301240 · Cited by 364
Ammann, P., Rizzoli, R., Bonjour, J. P., Bourrin, S., Meyer, J. M., Vassalli, P., & Garcia, I. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119333 · Cited by 310
The Functional Block of TNF but Not of IL-6 Prevents Bone Loss in Ovariectomized Mice
Kimble, R. B., Bain, S., & Pacifici, R. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.6.935 · Cited by 241
Clarke, B. L., & Khosla, S. (2010) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2010.02.014 · Cited by 221
Theobald, H. E. (2005) · Nutrition Bulletin · doi:10.1111/j.1467-3010.2005.00514.x · Cited by 203
Duan, Y., Turner, C. H., Kim, B.-T., & Seeman, E. (2001) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2001.16.12.2267 · Cited by 204
Vitamin K Nutrition and Osteoporosis
Binkley, N. C., & Suttie, J. W. (1995) · The Journal of Nutrition · doi:10.1093/jn/125.7.1812 · Cited by 185
The Association of Bone Mineral Density and Depression in an Older Population
Robbins, J., Hirsch, C., Whitmer, R., Cauley, J., Harris, T., & Study, F. T. C. H. (2001) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2001.49149.x · Cited by 180
Levothyroxine dose and risk of fractures in older adults: nested case-control study
Turner, M. R., Camacho, X., Fischer, H. D., Austin, P. C., Anderson, G. M., Rochon, P. A., & Lipscombe, L. L. (2011) · BMJ · doi:10.1136/bmj.d2238 · Cited by 152
Hodges, S. J., Pilkington, M. J., Stamp, T. C. B., Catterall, A., Shearer, M. J., Bitensky, L., & Chayen, J. (1991) · Bone · doi:10.1016/8756-3282(91)90027-g · Cited by 143
Roux, J.-P., Wegrzyn, J., Arlot, M. E., Guyen, O., Delmas, P. D., Chapurlat, R., & Bouxsein, M. L. (2010) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.090803 · Cited by 129
Persistent Increase in Bone Turnover in Graves’ Patients with Subclinical Hyperthyroidism
Kumeda, Y., Inaba, M., Tahara, H., Kurioka, Y., Ishikawa, T., Morii, H., & Nishizawa, Y. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.11.6979 · Cited by 123
Does bone change after biliopancreatic diversion?
Marceau, P., Biron, S., Lebel, S., Marceau, S., Hould, F. S., Simard, S., Dumont, M., & Fitzpatrick, L. A. (2002) · Journal of Gastrointestinal Surgery · doi:10.1016/s1091-255x(01)00086-5 · Cited by 105
Cline-Smith, A., Axelbaum, A., Shashkova, E., Chakraborty, M., Sanford, J., Panesar, P., Peterson, M., Cox, L., Baldan, A., Veis, D., et al. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3966 · Cited by 108
Bone Remodeling and the Microbiome
Pacifici, R. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a031203 · Cited by 101
Landin-Wilhelmsen, K., Wilhelmsen, L., Lappas, G., Ros�n, T., Lindstedt, G., Lundberg, P. A., Wilske, J., & Bengtsson, B. �. (1995) · Calcified Tissue International · doi:10.1007/bf00296339 · Cited by 90
Murray, T. É., Williams, D., & Lee, M. J. (2017) · Abdominal Radiology · doi:10.1007/s00261-017-1124-5 · Cited by 69
What do Norwegian women and men know about osteoporosis?
Magnus, J. H., Joakimsen, R. M., Berntsen, G. K., Tollan, A., & Søgaard, A. J. (1996) · Osteoporosis International · doi:10.1007/bf01626535 · Cited by 68
Adaptation of the Skeletal System During Long-Duration Spaceflight
Sibonga, J. D., Cavanagh, P. R., Lang, T. F., LeBlanc, A. D., Schneider, V. S., Shackelford, L. C., Smith, S. M., & Vico, L. (2007) · Clinical Reviews in Bone and Mineral Metabolism · doi:10.1007/s12018-008-9012-8 · Cited by 67
Bahamondes, L., Monteiro-Dantas, C., Espejo-Arce, X., dos Santos Fernandes, A. M., Lui-Filho, J. F., Perrotti, M., & Petta, C. A. (2006) · Human Reproduction · doi:10.1093/humrep/dei358 · Cited by 66
Cortical osteoclasts are less sensitive to etidronate than trabecular osteoclasts.
Chappard, D., Petitjean, M., Alexandre, C., Vico, L., Minaire, P., & Riffat, G. (1991) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650060704 · Cited by 65
In vivo leptin expression in cartilage and bone cells of growing rats and adult humans
Morroni, M., De Matteis, R., Palumbo, C., Ferretti, M., Villa, I., Rubinacci, A., Cinti, S., & Marotti, G. (2004) · Journal of Anatomy · doi:10.1111/j.0021-8782.2004.00333.x · Cited by 51
Hussein, A. I., Jackman, T. M., Morgan, S. R., Barest, G. D., & Morgan, E. F. (2013) · Osteoporosis International · doi:10.1007/s00198-013-2417-3 · Cited by 39
Buscemi, S., Verga, S., Cottone, S., Andronico, G., D’Orio, L., Mannino, V., Panzavecchia, D., Vitale, F., & Cerasola, G. (2007) · Journal of Endocrinological Investigation · doi:10.1007/bf03347430 · Cited by 35
Metadata
- Authors
- Riggs, B. L., & Melton, L. J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1986-06-26
- Volume
- 314
- Issue
- 26
- Pages
- 1676-1686
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4252543199
- Cited by
- 1,915
- References
- 3
- FWCI
- 107.84
- Type
- journal article
- Language
- en
- Open access
- closed
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