The contribution of bone to whole-organism physiology

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Leptin and the regulation of body weight in mammals

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Sox9 Modulates Proliferation and Expression of Osteogenic Markers of Adipose-Derived Stem Cells (ASC)

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Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene

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Bone Resorption by Osteoclasts

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Wnt signalling in stem cells and cancer

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Endocrine regulation of energy metabolism by the skeleton

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LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye Development

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Increased Insulin Sensitivity and Obesity Resistance in Mice Lacking the Protein Tyrosine Phosphatase-1B Gene

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Leptin Inhibits Bone Formation through a Hypothalamic Relay

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Involutional Osteoporosis

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Leptin Regulates Bone Formation via the Sympathetic Nervous System

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High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5

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Synthesis of Serotonin by a Second Tryptophan Hydroxylase Isoform

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Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation.

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Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

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Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

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Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling

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LDL-receptor-related proteins in Wnt signal transduction

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Leptin regulation of bone resorption by the sympathetic nervous system and CART

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A Mutation in the LDL Receptor–Related Protein 5 Gene Results in the Autosomal Dominant High–Bone-Mass Trait

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Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone

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THE WISDOM OF THE BODY

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A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance

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A Unitary Model for Involutional Osteoporosis: Estrogen Deficiency Causes Both Type I and Type II Osteoporosis in Postmenopausal Women and Contributes to Bone Loss in Aging Men

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Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism

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The Osteoblast: A Sophisticated Fibroblast under Central Surveillance

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<i>Cbfa1</i>-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

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General Conclusions: Teleonomic Mechanisms in Cellular Metabolism, Growth, and DifferentiationPreprint

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Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance

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Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

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Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts*1

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Osteocalcin differentially regulates β cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice

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Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

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ATF4 Is a Substrate of RSK2 and an Essential Regulator of Osteoblast Biology

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Adipose Tissue Selective Insulin Receptor Knockout Protects against Obesity and Obesity-Related Glucose Intolerance

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Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis

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Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition

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A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure

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Endocrine Regulation of Male Fertility by the Skeleton

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Introduction a? l'e?tude de la me?decine expe?rimentale

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Osteocyte Wnt/β-Catenin Signaling Is Required for Normal Bone Homeostasis

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Norrin, Frizzled-4, and Lrp5 Signaling in Endothelial Cells Controls a Genetic Program for Retinal Vascularization

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Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo

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Lrp5 functions in bone to regulate bone mass

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Hematopoietic origin of pathological grooming in Hoxb8 mutant mice

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Serum leptin level is a regulator of bone mass

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Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis

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Identification of a Novel Extracellular Cation-sensing G-protein-coupled Receptor

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Wg/Wnt Signal Can Be Transmitted through Arrow/LRP5,6 and Axin Independently of Zw3/Gsk3β Activity

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Relationship Between Central and Peripheral Serotonin Indexes in Depressed and Suicidal Psychiatric Inpatients

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A method for decarboxylation of gamma-carboxyglutamic acid in proteins. Properties of the decarboxylated gamma-carboxyglutamic acid protein from calf bone.

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Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress

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Congenital Leptin Deficiency Due to Homozygosity for the Δ133G Mutation: Report of Another Case and Evaluation of Response to Four Years of Leptin Therapy

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The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity

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ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae

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The Calcium-Sensing Receptor: A Molecular Perspective

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Central control of bone remodeling by neuromedin U

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Impaired gastric acidification negatively affects calcium homeostasis and bone mass

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Serotonin neuronal function and selective serotonin reuptake inhibitor treatment in anorexia and bulimia nervosa

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Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function

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Improved Glucose Homeostasis in Mice with Muscle-Specific Deletion of Protein-Tyrosine Phosphatase 1B

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Gene array analysis of Wnt-regulated genes in C3H10T1/2 cells

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Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight

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Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice

Bartell, S. M., Rayalam, S., Ambati, S., Gaddam, D. R., Hartzell, D. L., Hamrick, M. W., She, J., Della‐Fera, M. A., & Baile, C. A. (2011) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.406 · Cited by 156 · see citing works

Discovery and Characterization of Novel Tryptophan Hydroxylase Inhibitors That Selectively Inhibit Serotonin Synthesis in the Gastrointestinal Tract

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Protective effect of β blockers in postmenopausal women: Influence on fractures, bone density, micro and macroarchitecture

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Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo

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CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neuronsPreprint

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Bone and glucose metabolism: A two-way street

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Stimulation of Bone Resorption by Parathyroid Hormone in Tissue Culture

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Update in Serotonin and Bone

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Relation of serum serotonin levels to bone density and structural parameters in women

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Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications

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Low density lipoprotein receptor‐related protein 5 (LRP5) mutations and osteoporosis, impaired glucose metabolism and hypercholesterolaemia

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Leptin Inhibits Bone Formation Not Only in Rodents, but Also in Sheep

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Minireview: Fibroblast Growth Factor 23 in Phosphate Homeostasis and Bone Metabolism

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The Neuroendocrine Basis of Anorexia Nervosa and Its Impact on Bone Metabolism

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Lower Uncarboxylated Osteocalcin Concentrations in Children with Prediabetes Is Associated with β-Cell Function

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Basic and clinical aspects of osteoporosis in inflammatory bowel disease

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Efficacy of serotonin inhibition in mouse models of bone loss

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