The DOI matches its Crossref record.
Estrogen and the Risk of Breast Cancer
Abstract
The connection between breast cancer and estrogen has been recognized for more than 100 years, since George Beatson demonstrated that bilateral oophorectomy resulted in the remission of breast cancer in premenopausal women.1 Subsequent evidence has implicated both endogenous and exogenous estrogen in the pathogenesis of breast cancer. In this article, we review the relation between estrogen and the risk of breast cancer.Estrogen and Breast CarcinogenesisExperimental data strongly suggest that estrogens have a role in the development and growth of breast cancer.2 Although the exact mechanisms remain to be fully elucidated, the alkylation of cellular molecules and the generation . . .
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Ritchie, M. D., Hahn, L. W., Roodi, N., Bailey, L. R., Dupont, W. D., Parl, F. F., & Moore, J. H. (2001) · The American Journal of Human Genetics · doi:10.1086/321276 · Cited by 1,898
Goss, P. E., Ingle, J. N., Martino, S., Robert, N. J., Muss, H. B., Piccart, M. J., Castiglione, M., Tu, D., Shepherd, L. E., Pritchard, K. I., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa032312 · Cited by 1,795
Self-citationGoss, P. E., Ingle, J. N., Martino, S., Robert, N. J., Muss, H. B., Piccart, M. J., Castiglione, M., Tu, D., Shepherd, L. E., Pritchard, K. I., et al. (2005) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/dji250 · Cited by 1,118
Self-citationExemestane for Breast-Cancer Prevention in Postmenopausal Women
Goss, P. E., Ingle, J. N., Alés-Martínez, J. E., Cheung, A. M., Chlebowski, R. T., Wactawski-Wende, J., McTiernan, A., Robbins, J., Johnson, K. C., Martin, L. W., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1103507 · Cited by 970
Self-citationControl of mammary stem cell function by steroid hormone signalling
Asselin-Labat, M.-L., Vaillant, F., Sheridan, J. M., Pal, B., Wu, D., Simpson, E. R., Yasuda, H., Smyth, G. K., Martin, T. J., Lindeman, G. J., et al. (2010) · Nature · doi:10.1038/nature09027 · Cited by 693
Weight Loss in Breast Cancer Patient Management
Chlebowski, R. T., Aiello, E. J., & McTiernan, A. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.20.4.1128 · Cited by 623
Pal, B., Chen, Y., Vaillant, F., Capaldo, B. D., Joyce, R., Song, X., Bryant, V. L., Penington, J. S., Di Stefano, L., Tubau Ribera, N., et al. (2021) · The EMBO Journal · doi:10.15252/embj.2020107333 · Cited by 469
Blask, D. E., Brainard, G. C., Dauchy, R. T., Hanifin, J. P., Davidson, L. K., Krause, J. A., Sauer, L. A., Rivera-Bermudez, M. A., Dubocovich, M. L., Jasser, S. A., et al. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-1945 · Cited by 432
Oestrogen exposure and breast cancer risk
Travis, R. C., & Key, T. J. (2003) · Breast Cancer Research · doi:10.1186/bcr628 · Cited by 346
Adiposity, Adult Weight Change, and Postmenopausal Breast Cancer Risk
Ahn, J., Schatzkin, A., Lacey, J. V., Albanes, D., Ballard-Barbash, R., Adams, K. F., Kipnis, V., Mouw, T., Hollenbeck, A. R., & Leitzmann, M. F. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.19.2091 · Cited by 318
Bhandari, R. K., Deem, S. L., Holliday, D. K., Jandegian, C. M., Kassotis, C. D., Nagel, S. C., Tillitt, D. E., vom Saal, F. S., & Rosenfeld, C. S. (2015) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2014.09.014 · Cited by 297
Terry, P. D., Rohan, T. E., & Wolk, A. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.3.532 · Cited by 285
Xu, X., Roman, J. M., Issaq, H. J., Keefer, L. K., Veenstra, T. D., & Ziegler, R. G. (2007) · Analytical Chemistry · doi:10.1021/ac070494j · Cited by 260
Tamimi, R. M., Byrne, C., Colditz, G. A., & Hankinson, S. E. (2007) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djm062 · Cited by 258
Xu, X., Veenstra, T. D., Fox, S. D., Roman, J. M., Issaq, H. J., Falk, R., Saavedra, J. E., Keefer, L. K., & Ziegler, R. G. (2005) · Analytical Chemistry · doi:10.1021/ac050697c · Cited by 227
17β-Estradiol Inhibits Iron Hormone Hepcidin Through an Estrogen Responsive Element Half-Site
Yang, Q., Jian, J., Katz, S., Abramson, S. B., & Huang, X. (2012) · Endocrinology · doi:10.1210/en.2011-2045 · Cited by 208
Effects of estrogen on breast cancer development: Role of estrogen receptor independent mechanisms
Yue, W., Wang, J., Li, Y., Fan, P., Liu, G., Zhang, N., Conaway, M., Wang, H., Korach, K. S., Bocchinfuso, W., et al. (2010) · International Journal of Cancer · doi:10.1002/ijc.25207 · Cited by 196
A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila
Okamoto, N., Viswanatha, R., Bittar, R., Li, Z., Haga-Yamanaka, S., Perrimon, N., & Yamanaka, N. (2018) · Developmental Cell · doi:10.1016/j.devcel.2018.09.012 · Cited by 144
Role of dietary bioactive natural products in estrogen receptor-positive breast cancer
Bak, M. J., Das Gupta, S., Wahler, J., & Suh, N. (2016) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2016.03.001 · Cited by 80
CAPER, a novel regulator of human breast cancer progression
Mercier, I., Gonzales, D. M., Quann, K., Pestell, T. G., Molchansky, A., Sotgia, F., Hulit, J., Gandara, R., Wang, C., Pestell, R. G., et al. (2014) · Cell Cycle · doi:10.4161/cc.28156 · Cited by 45
Buwalda, B., & Schagen, S. B. (2013) · Life Sciences · doi:10.1016/j.lfs.2012.12.012 · Cited by 43
Menopausal hormone therapy and breast cancer
Santen, R. J. (2014) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.06.010 · Cited by 41
Pukos, N., & McTigue, D. M. (2020) · PLOS ONE · doi:10.1371/journal.pone.0235232 · Cited by 9
Metadata
- Authors
- Clemons, M., & Goss, P.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2001-01-25
- Volume
- 344
- Issue
- 4
- Pages
- 276-285
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2313869316
- Cited by
- 1,096
- References
- 0
- FWCI
- 30.54
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
