Initial management of glycemia in type 2 diabetes mellitus

Nathan, David M.

doi:10.1056/nejmcp021106

Cited by 366Diabetes Treatment and ManagementDiabetes Management and ResearchDiabetes, Cardiovascular Risks, and Lipoproteins

Initial management of glycemia in type 2 diabetes mellitus

Nathan, David M.·2002·New England Journal of Medicine

DOI 10.1056/nejmcp021106

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Abstract

An asymptomatic 45-year-old Hispanic man has a fasting plasma glucose level of 142 mg per deciliter (7.9 mmol per liter) on initial evaluation and 139 mg per deciliter (7.7 mmol per liter) on reevaluation. Other than a steady gain in weight since college and borderline hypertension, his medical history is unremarkable. He is 175 cm (5 ft 9 in.) tall and weighs 95 kg (209 lb; body-mass index, 31.2), and his blood pressure is 138/88 mm Hg. Physical examination is notable only for abdominal obesity and absent ankle reflexes. How should this patient be treated?

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Authors: Nathan, D. M.
Affiliations: Harvard University (US)
Corresponding author: Nathan, David M.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2002-10-24
Volume: 347
Issue: 17
Pages: 1342-1349
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmcp021106
OpenAlex: W2090609048
Cited by: 359
References: 57
Citations by year: 2026: 2 · 2025: 1 · 2024: 3 · 2023: 1 · 2022: 2 · 2021: 6 · 2020: 6 · 2019: 8 · 2018: 9 · 2017: 13 · 2016: 13 · 2015: 7 · 2014: 20 · 2013: 16 · 2012: 15
FWCI: 14.07
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: type 2 diabetes, glycemic control, initial management, fasting blood glucose, obesity, borderline hypertension, Hispanic patients, weight gain
MeSH terms: Combined Modality Therapy, Diabetes Mellitus, Diabetes Mellitus, Type 2, Drug Therapy, Combination, Humans, Hyperglycemia, Hypoglycemic Agents, Male, Middle Aged, Obesity, Weight Loss, Practice Guidelines as Topic

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Initial management of glycemia in type 2 diabetes mellitus

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