The DOI matches its Crossref record; 52 of the 53 references it cites were found in a registry or an index.
Different amygdala subregions mediate valence-related and attentional effects of oxytocin in humans
Open accessAbstract
The neuropeptide oxytocin enhances the processing of positive social stimuli and improves the capacity to effectively attend the eye region of conspecifics. To investigate the neural basis of these effects, we combined intranasal oxytocin administration with high-resolution functional magnetic resonance imaging in a unique emotion classification task. Emotional faces were briefly presented while controlling for the initial fixation, and measuring subsequent eye movements. Oxytocin had differential effects on the activity of specific amygdala subregions. On the one hand, it attenuated activation in lateral and dorsal regions of the anterior amygdala for fearful faces but enhanced activity for happy expressions, thus indicating a shift of the processing focus toward positive social stimuli. On the other hand, oxytocin increased the likelihood of reflexive gaze shifts toward the eye region irrespective of the depicted emotional expression. This gazing pattern was related to an increase of activity in the posterior amygdala and an enhanced functional coupling of this region to the superior colliculi. Thus, different behavioral effects of oxytocin seem to be closely related its specific modulatory influence on subregions within the human amygdala.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Functioning as both a neurotransmitter and a hormone, oxytocin's targets are widespread and include the hippocampus and the amygdala (10–12).”
From Oxytocin promotes human ethnocentrism (2011) · cites this paper as [12]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“and the activity of amygdala subregions is also modulated by OXT (Gamer et al., 2010).”
From Oxytocin Modulates Social Distance between Males and Females (2012) · cites this paper as Gamer et al., 2010
The cited source says what the claim attributes to it.
In the citing paper
“These studies have repeatedly demonstrated decreased amygdala activation, which has been interpreted as a neural mechanism underlying oxytocin’s anxiolytic effects18,20,21.”
From Randomized clinical trial shows no substantial modulation of empathy-related neural activation by intranasal oxytocin in autism (2021) · cites this paper as [21]
In the citing paper
“This dose, administered intranasally, has been shown in nonhuman primates to increase OT levels in cerebrospinal fluid significantly (54) and to modulate social behavior (65), as well as to affect brain activity (66) and phasic activity of the parasympathetic nervous system (67) in humans.”
From Oxytocin under opioid antagonism leads to supralinear enhancement of social attention (2017) · cites this paper as [66]
In the citing paper
“separate OXT-application studies in humans have indicated that there may be differential amygdala reactivity to fearful faces and fearful/threatening scenes in men (14, 15) and women (16, 17).”
From Oxytocin, the peptide that bonds the sexes also divides them (2016) · cites this paper as [14]
In the citing paper
“Previous studies on amygdala responses to fearful faces and fearful/threatening scenes (14 -17, 30) and social risk (31) have also indicated that OXT may induce sex-dependent changes in amygdala activation to emotional stimuli.”
From Oxytocin, the peptide that bonds the sexes also divides them (2016) · cites this paper as [14]
In the citing paper
“In humans, alterations in amygdala responses to positive and negative emotions have been reported in neuropsychiatric conditions, such as autism and schizophrenia [72,73], in association with OXTR genetic variants [41,102] or following intranasal OXT [33,36,38,103].”
From Oxytocin Signaling in the Central Amygdala Modulates Emotion Discrimination in Mice (2019) · cites this paper as [103]
In the citing paper
“In this context, the insula17 as well as the amygdala seem to be key target regions in the brain, with oxytocin modulating amygdala responsiveness to emotional faces18–22 or social stimuli in general23.”
From Randomized clinical trial shows no substantial modulation of empathy-related neural activation by intranasal oxytocin in autism (2021) · cites this paper as [21]
In the citing paper
“attenuating activation of amygdala to social stimuli (Baumgartner et al, 2008;Domes et al, 2007a;Gamer et al, 2010;Kirsch et al, 2005)”
From Chronic and acute intranasal oxytocin produce divergent social effects in mice (2014) · cites this paper as Gamer et al, 2010
In the citing paper
“Gamer and colleagues found that oxytocin’s effects on amygdala activity elicited by emotional faces was dependent on the valence of stimuli but the effects of oxytocin on enhancement of gaze shifts towards the eyes was valence independent (Gamer et al., 2010).”
From Oxytocin, motivation and the role of dopamine (2014) · cites this paper as Gamer et al., 2010
In the citing paper
“In addition, oxytocin suppresses amygdala activation for fearful faces but enhances activity for happy faces (Gamer et al., 2010).”
From Oxytocin, motivation and the role of dopamine (2014) · cites this paper as Gamer et al., 2010
In the citing paper
“Oxytocin decreases amygdala activation during the perception of fear-inducing or aversive social stimuli; it has been suggested that this explains the stress-reducing effects of oxytocin (Gamer et al., 2010;Riem et al., 2011).”
From Oxytocin effects on complex brain networks are moderated by experiences of maternal love withdrawal (2013) · cites this paper as Gamer et al., 2010
In the citing paper
“Because projections between the amygdala and brainstem are involved in fear behavior and arousal (LeDoux, 2000) it has been suggested that decreased amygdala activation might be the underlying neural mechanism of the anxiolytic effects of oxytocin (Gamer et al., 2010;Riem et al., 2011).”
From Oxytocin effects on complex brain networks are moderated by experiences of maternal love withdrawal (2013) · cites this paper as Gamer et al., 2010
In the citing paper
“Research in humans has almost exclusively focused on the role of oxytocin in the regulation of prosocial behavior, including trust, attachment, and sexual behavior (2–5), largely ignoring potential effects of the neuropeptide on ingestive behavior and metabolism.”
From Oxytocin Reduces Reward-Driven Food Intake in Humans (2013) · cites this paper as [4]
In the citing paper
“intranasal oxytocin administration has been shown to reliably modulate neuropsychological functions in a series of studies (2–5) in the absence of relevant side effects (16).”
From Oxytocin Reduces Reward-Driven Food Intake in Humans (2013) · cites this paper as [4]
In the citing paper
“Following intranasal OT (Syntocinon spray, Novartis), humans spend more time visually inspecting the eye region of faces compared to placebo (i.e., all inactive ingredients except for the peptide) (Gamer et al., 2010; Guastella et al., 2008).”
From Oxytocin and social cognition in rhesus macaques: Implications for understanding and treating human psychopathology (2014) · cites this paper as Gamer et al., 2010
In the citing paper
“Furthermore, OT inhalation reduces amygdala activation when viewing fearful faces but increases amygdala activation when viewing happy faces (Gamer et al., 2010).”
From Oxytocin and social cognition in rhesus macaques: Implications for understanding and treating human psychopathology (2014) · cites this paper as Gamer et al., 2010
In the citing paper
“Importantly, the activity of amygdala sub-regions has been shown to be modulated by the neuropeptide oxytocin (OT; Gamer et al., 2010;Hurlemann et al., 2010), indicating that OT is a candidate hormone for modulating interpersonal distance.”
From OT promotes closer interpersonal distance among highly empathic individuals (2015) · cites this paper as Gamer et al., 2010
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Tzourio-Mazoyer, N., Landeau, B., Papathanassiou, D., Crivello, F., Etard, O., Delcroix, N., Mazoyer, B., & Joliot, M. (2002) · NeuroImage · doi:10.1006/nimg.2001.0978 · Cited by 16,319
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690
The amygdala: vigilance and emotion
Davis, M., & Whalen, P. J. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000812 · Cited by 2,882
Adolphs, R., Tranel, D., Damasio, H., & Damasio, A. (1994) · Nature · doi:10.1038/372669a0 · Cited by 2,360
Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00465-7 · Cited by 2,091
The Amygdaloid Complex: Anatomy and Physiology
SAH, P., FABER, E. S. L., LOPEZ DE ARMENTIA, M., & POWER, J. (2003) · Physiological Reviews · doi:10.1152/physrev.00002.2003 · Cited by 1,745
Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans
Kirsch, P., Esslinger, C., Chen, Q., Mier, D., Lis, S., Siddhanti, S., Gruppe, H., Mattay, V. S., Gallhofer, B., & Meyer-Lindenberg, A. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3984-05.2005 · Cited by 1,639
Jeurgen, K., Assheuer, J., & Paxinos, G. (1997) · Medical Entomology and Zoology · Cited by 1,403
Sniffing neuropeptides: A transnasal approach to the human brain
Born, J., Lange, T., Kern, W., McGregor, G. P., Bickel, U., & Fehm, H. L. (2002) · Nature Neuroscience · doi:10.1038/nn0602-849 · Cited by 1,356
A mechanism for impaired fear recognition after amygdala damage
Adolphs, R., Gosselin, F., Buchanan, T. W., Tranel, D., Schyns, P., & Damasio, A. R. (2005) · Nature · doi:10.1038/nature03086 · Cited by 1,331 · cited 4×
“This observation precisely accounts for the clinical findings of reduced spontaneous fixations on the eye region and a failure to identify fearful expressions in a patient with complete bilateral amygdala damage (20, 21).”
BackgroundInfluential
Cited by
Sorted by citations
Items 401–487 of 487
Heinrichs, M., Chen, F. S., & Domes, G. (2012) · Wiley eBooks · doi:10.1002/9781119945901.ch8 · Cited by 4
Oxytocin and opioid antagonists: A dual approach to improving social behavior
Monte, O. D., Gangopadhyay, P., Putnam, P. T., & Chang, S. W. C. (2025) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.15376 · Cited by 3
“32,106,107 Additionally, OT attenuates amygdala activity in response to aversive stimuli, 102,108–110 highlighting its role in regulating emotional responses within social contexts.”
The oxytocin-attention loop of loneliness
Shamai‐Leshem, D., Radai, T., & Shamay‐Tsoory, S. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106395 · Cited by 4
Oxytocin homogenizes horse group organization
Brooks, J., Maeda, T., Ringhofer, M., & Yamamoto, S. (2024) · iScience · doi:10.1016/j.isci.2024.110356 · Cited by 5
“6 The more diffuse groups (lower network density and higher average inter-individual distances) may be hypothesized to be driven in part through OT’s known anxiolytic effects (e.g., Brosnan et al., 63 2015; Gamer et al., 64 2010; Kirsch et al., 7 2005).”
Uzar, M., Dmitrzak‐Węglarz, M., & Słopień, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212046 · Cited by 5
“In addition, there is evidence for a relationship between oxytocin-induced changes in social attention and strengthened connections between the amygdala and the superior colliculus [116,119,120].”
Emotional imagination of negative situations: Functional neuroimaging in anorexia and bulimia
D’Agata, F., Caroppo, P., Spalatro, A. V., Lavagnino, L., Daga, G. A., Boghi, A., Bergui, M., Cicerale, A., Vitiello, B., Fassino, S., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0231684 · Cited by 4
“Commenting on the trends evidenced, BN showed some relevant activation in the CM portion of the right amygdala, both CM and BL respond to aversive stimuli, but CM has been reported as the primary output structure, important for the arousal and fear response activation [33,65].”
BackgroundCan Oxytocin Improve Core Brain and Behavioral Features of Autism Spectrum Disorders in Children?
Gordon, I. (2013) · Research and perspectives in neurosciences · doi:10.1007/978-3-319-02904-7_11 · Cited by 3
Wu, W. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.107645 · Cited by 3
Sorenson, K., Kendall, E., Grell, H., Kang, M., Shaffer, C. L., & Hwang, S. (2023) · Journal of Psychiatry and Brain Science · doi:10.20900/jpbs.20230008 · Cited by 3
“On the other hand, there are also other studies showing that OXT can enhance the activation of the amygdala, [8–10], nucleus accumbens, striatum and certain cortices and gyri in the frontal lobe [11].”
ResultIntranasal oxytocin for autism spectrum disorders (ASD)
Feng, L., Wong, J. C., Mahendran, R., Chan, E. S., & Spencer, M. D. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010928.pub2 · Cited by 3
Verhagen, M., Engels, R. C. M. E., & van Roekel, E. (2014) · Open Journal of Depression · doi:10.4236/ojd.2014.34017 · Cited by 3
The Human Amygdaloid Complex: Cellular Architecture and Dopaminergic Innervation
García‐Amado, M., & Prensa, L. (2017) · InTech eBooks · doi:10.5772/intechopen.68391 · Cited by 3
“Sims and Williams [49] 1Brady [52] 2Price et al.”
BackgroundChen, J., Luo, Y. L. L., Xie, Y., Yang, Z., & Cai, H. (2021) · Hormones and Behavior · doi:10.1016/j.yhbeh.2020.104920 · Cited by 3
From histology to macroscale function in the human amygdala
Auer, H., Cabalo, D. G., Rodríguez‐Cruces, R., Benkarim, O. M., Paquola, C., DeKraker, J., Wang, Y., Valk, S. L., Bernhardt, B. C., & Royer, J. (2025) · eLife · doi:10.7554/elife.101950.3 · Cited by 2
Ferreira, S., Freire, F., & Prata, D. P. (2025) · PLoS ONE · doi:10.1371/journal.pone.0327764 · Cited by 2
“These included five explicit recognition studies and one that employed an implicit task [67,143–147].”
InfluentialLuther, L., Mathis, R. F., Keller, W. R., Buchanan, R. W., Gold, J. M., Koeing, J. I., & Strauss, G. P. (2025) · Schizophrenia Research · doi:10.1016/j.schres.2025.10.010 · Cited by 2
The Function of Oxytocin in Memory —A General Review of Oxytocin’s Effect on Memory
Gao, F. (2023) · World Journal of Neuroscience · doi:10.4236/wjns.2023.134013 · Cited by 3
Yang, Y., & Gamer, M. (2025) · Scientific Reports · doi:10.1038/s41598-025-12327-6 · Cited by 2
“Although it might seem plausible to assume that fixating a diagnostic feature enhances emotion recognition accuracy, this effect was only inconsistently observed in previous studies 4,10,11,33,55 , and was not supported in our current data.”
Oxytocin – ein prosoziales Hormon
Bertsch, K., & Herpertz, S. C. (2010) · Gynäkologische Endokrinologie · doi:10.1007/s10304-010-0388-4 · Cited by 2
“Auch in Human studien zeigte sich wiederholt eine reduzierte Reaktivität der (anterioren) Amygdala auf bedrohliche soziale Reize infolge einer intra nasalen OT-Administration [6, 13, 21].”
BackgroundInfluentialNeumann, I. D. (2012) · Acta Neuropsychiatrica · doi:10.1111/j.1601-5215.2011.00672.x · Cited by 2
“To further underline the prosocial effects of oxytocin, it was shown that oxytocin-treated subjects make more eye movements towards the eye region when viewing human faces (17), and show an improved ability to read the mental state of others using social cues from facial expressions (18).”
BackgroundNeurochemistry of Prosocial Decision Making
Declerck, C. H., & Boone, C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801303-8.00003-3 · Cited by 2
Measuring how genetic and epigenetic variants can filter emotion perception
Taschereau‐Dumouchel, V., Hétu, S., Chagnon, Y. C., & Jackson, P. L. (2015) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000102 · Cited by 2
“…have indicated that intranasal oxytocin modulates the activity of lateral and dorsal regions of the anterior amygdala during the perception of facial expressions and also increases the probability of directing the gaze toward the eye region as a function of emotional valence (Gamer et al., 2010).”
BackgroundMethodNuman, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0008 · Cited by 2
Hormonal Control of Maternal Behavior in Nonhuman Mammals
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0003 · Cited by 2
Personality Dimensions in Psychopathy: Potential Explanatory Models for Primary and Secondary TraitsPreprint
Murphy, B. A., & Giurgiutiu, D. (2012) · SSRN Electronic Journal · doi:10.2139/ssrn.1978268 · Cited by 1
From histology to macroscale function in the human amygdalaPreprint
Auer, H., Cabalo, D. G., Rodríguez‐Cruces, R., Benkarim, O. M., Paquola, C., DeKraker, J., Wang, Y., Valk, S. L., Bernhardt, B. C., & Royer, J. (2025) · eLife · doi:10.7554/elife.101950.2 · Cited by 2
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0002 · Cited by 1
Jongerius, C., Hillen, M. A., Smets, E. M. A., Mol, M. J., Kooij, E. S., de Nood, M. A., Dalmaijer, E. S., Fliers, E., Romijn, J. A., & Quintana, D. S. (2023) · Endocrine Connections · doi:10.1530/ec-22-0377 · Cited by 1
Guo, X., Zhang, L., Zhang, Q., Kendrick, K. M., & Yao, S. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106679 · Cited by 1
Oxytocin, vasopressin, sociality, and pathogen avoidance
Kavaliers, M., & Choleris, E. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139017855.017 · Cited by 1
Rol Modulador de la Oxitocina en la Interacción Social y el Estrés Social
Flórez-Acevedo, S., & Cárdenas, F. P. (2017) · Universitas Psychologica · doi:10.11144/javeriana.upsy15-5.rmoi · Cited by 1
Regulation of Oxytocin on Empathy and Its Neural Mechanism
Yue, G. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.112743 · Cited by 1
Oxytocin’s role in the interaction between emotion and cognitive control
Ganzel, A. R., Shalev, H., Hochman, S., Zultan, R., Cohen, N., & Naparstek, S. (2025) · Biological Psychology · doi:10.1016/j.biopsycho.2025.109004 · Cited by 2
Older adults looking at dog pictures - psychobiological effects
Correia‐Caeiro, C., Romero, T., Guo, K., & Mills, D. S. (2025) · Acta Psychologica · doi:10.1016/j.actpsy.2025.105221 · Cited by 1
“…not only is maternal oxytocin level positively correlated with the duration of mother-to-infant gaze (Kim et al., 2014), but administering oxytocin (e.g., via nasal spray) increases fixation duration and count towards the eye area (Auyeung et al., 2015; Gamer et al., 2010; Guastella et al., 2008).”
Experimental Usage of Oxytocin to Combat Deficits in Social Cognition in Schizophrenia
Taş, C., Brown, E. C., Gonzalez, C., & Brüne, M. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405172-0.00018-1 · Cited by 1
“Several functional magnetic resonance imaging (fMRI) studies reported correlations between amygdala activity and the accurate identification of emotions, which was modifiable by oxytocin administration (Domes et al., 2007; Gamer et al., 2010).”
BackgroundNuman, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0001 · Cited by 1
Central Neural Circuits Regulating Maternal Behavior in Nonhuman Mammals
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0005 · Cited by 1
Alloparental Behavior and Paternal Behavior in Nonhuman Mammals
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0007 · Cited by 1
Antisocial behaviour in adolescents: exploring and improving emotion processing deficits
Hubble, K. (2015) · ORCA Online Research @Cardiff (Cardiff University) · Cited by 1
Intranasal oxytocin modulates very early visual processing of emotional facesPreprint
Hugrass, L., Labuschagne, I., Mu, E., Price, A., & Crewther, D. P. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.15.440078 · Cited by 1
“…have shown that intranasal OXT administration can suppress amygdala responses to fearful and happy faces (Domes et al., 2007a; Kirsch et al., 2005), and can influence functional connectivity between superior colliculus and amygdala (Gamer et al., 2010) and frontal cortex (Sripada et al., 2012).”
BackgroundJohansson, A. (2012) · Doria (University of Helsinki) · Cited by 1
Effects of central neuropeptides on social preference and social recognition in male rats
Lukas, M. (2011) · University of Regensburg Publication Server (University of Regensburg) · doi:10.5283/epub.22540
Die Bedeutung von Körperkontakt und Körperkontaktstörungen
Jansen, F., & Streit, U. (2014) · Springer eBooks · doi:10.1007/978-3-642-41118-2_2
The Influence of Oxytocin on Older Adults’ Emotion Processing
Campbell, A. (2015) · Otago University Research Archive (University of Otago)
Blushing and gaze avoidance in social anxiety disorder : a structural neuroanatomical investigation
der Merwe, V., & Thandiwe, N. (2014) · Open University of Cape Town (University of Cape Town)
Psychosoziale Effekte von Oxytocin und Vasopressin und ihre therapeutischen Anwendungsmöglichkeiten
Thienel, M., & Hallschmid, M. (2012) · Zeitschrift für Medizinische Psychologie · doi:10.3233/zmp-2012-210005
Effect of intranasal oxytocin on pro-social behavior in social anxiety disorder
Fang, A. (2014) · OpenBU (Boston University)
Cotton, S. (2011) · Chapman & Hall/CRC eBooks · doi:10.1201/b11443-14
Physiological correlates of emotion regulation in depersonalization disorder
Monde, K.-M. (2014) · CUNY Academic Works (City University of New York)
Riem, M. M. E., Bakermans‐Kranenburg, M. J., van IJzendoorn, M. H., Out, D., & Rombouts, S. A. R. B. (2016) · Dziecko Krzywdzone. Teoria, badania, praktyka
Measuring Responses to Nonverbal Social Signals: Research on Affect Receiving Ability
Buck, R. W., Miller, M., & Powers, S. R. (2017) · Cambridge University Press eBooks · doi:10.1017/9781316676202.005
da Silva, J. U. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.47.2017.tde-25072017-172834
Lima, J. P. C. (2018) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.47.2018.tde-19042018-161017
On oxytocin and social behavior
Hovey, D. (2018) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Evolutionary Perspectives on the Parental Brain
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0011
Anxiety Reduction and Maternal Aggression in Postpartum Nonhuman Mammals
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0006
Development of the Parental Brain in Nonhuman Mammals
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0009
Development of the Parental Brain in Humans
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0010
Brain Mechanisms Regulating Maternal Behavior in Nonhuman Mammals
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0004
Zarei, S. A., Tomaz, C. A. B., de Vasconcelos, C. A. C., Tavares, M. C. H., & Sarani, M. (2020) · International Journal for Innovation Education and Research · doi:10.31686/ijier.vol8.iss8.2528
“So, oxytocin may help detect fear or happiness from subtle cues around the eyes [46].”
BackgroundCollectivity as a Basic Instinct for Survival
Ünsalver, B. Ö., Ceylan, M. E., Dönmez, A., Yertutanol, F. D. K., & Evrensel, A. (2021) · The Journal of Neurobehavioral Sciences · doi:10.4103/jnbs.jnbs_20_21
Jongerius, C., Hillen, M. A., Smets, E. M. A., Mol, M. J., Kooij, E. S., de Nood, M. A., Dalmaijer, E. S., Fliers, E., Romijn, J. A., & Quintana, D. S. (2021) · doi:10.31219/osf.io/x6rf4
Cotton, S. (2011) · Chapman & Hall/CRC eBooks · doi:10.1201/b11443-16
Oxytocin - not only a "social" neuropeptide
Brodmann, K. (2016) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-5978
Intranasal oxytocin for autism spectrum disorders (ASD)
Feng, L., Wong, J. C., Mahendran, R., Chan, E. S., & Spencer, M. D. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010928
Retracted(2015) · Elsevier eBooks · doi:10.1016/b978-0-12-416040-8.16001-8
Morris, J., Skyberg, A. M., Newman, B. T., Graves, A., Goldstein, A., Brindley, S., Kim, M., Druzgal, T. J., & Connelly, J. J. (2022) · Research Square · doi:10.21203/rs.3.rs-2062536/v1
Jeung-Maarse, H. (2023) · Research Publications (Maastricht University) · doi:10.26481/dis.20230918hj
Cognitive neural mechanisms underlying the impact of oxytocin on conditioned fear processing
Pan, F. E. N. G., Zhao, H., JIANG, Y., Zhang, Y., & Tingyong, F. E. N. G. (2024) · Advances in Psychological Science · doi:10.3724/sp.j.1042.2024.00557
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.002.0006
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.002.0003
Abbreviations Used for Major Brain Regions
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.002.0007
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.002.0004
Infants' salivary oxytocin and positive affective reactions to people
Zeng, G., Leung, T. S., Maylott, S. E., Malik, A., Adornato, A. A., Lebowitz, M., Messinger, D. S., Szeto, A., Feldman, R., & Simpson, E. A. (2023) · Hormones and Behavior · doi:10.1016/j.yhbeh.2024.105579 · Cited by 2
Gorina, Y. V., Lopatina, O. L., & Mararitsa, L. V. (2024) · Annals of Clinical and Experimental Neurology · doi:10.17816/acen.1047
From histology to macroscale function in the human amygdalaPreprint
Auer, H., Cabalo, D. G., Rodríguez‐Cruces, R., Benkarim, O. M., Paquola, C., DeKraker, J., Wang, Y., Valk, S. L., Bernhardt, B. C., & Royer, J. (2024) · eLife · doi:10.7554/elife.101950.1
An Integrative Approach to Moral DevelopmentDuring Adolescence
Baird, A. A., & Matthews, M. M. (2025) · Cambridge University Press eBooks · doi:10.1017/9781108894357.024
Origins, Development, and Variation
Malle, B., & Robbins, P. (2025) · Cambridge University Press eBooks · doi:10.1017/9781108894357.021
Akkermans, S. E. A. (2012) · Utrecht University Repository (Utrecht University)
小岩, 信. (2013) · doi:10.11427/jhas.9.15
Gaze and behavior tracking in animal research: Granularity, automation, and technological choice
Kano, F., & Chan, A. H. H. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-29068-8.00207-5
Huc, M., Nikolic, M., Power, L., McQuaid, R. J., & Jaworska, N. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106610
Zhou, M., Wang, X., Zhang, Y., Zeng, Z., Zhang, Q., Kendrick, K. M., & Yao, S. (2026) · Psychological Medicine · doi:10.1017/s0033291726103602
“These findings together suggest that OT may influence emotional recognition even at an early stage of visual attentional processing, which may be underpinned by OT modulating amygdala reactivity (Gamer, Zurowski, & Büchel, 2010; Kanat et al., 2015; Kanat, Heinrichs, Schwarzwald, & Domes, 2015).”
The peripersonal space : a space to inter-act
Patané, I. (2018) · theses.fr (ABES) · doi:10.70675/65489b37z5297z4a85z96cczc535ef9ca767
Ameloot, A., Disarbois, É., Elseedy, H., Duperron, C., Grinevich, V., Sirigu, A., & Duhamel, J. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.17.751377
“In both humans and macaques, IN-OT attenuates responses to threatening social cues and reduces vigilance toward socially aversive stimuli 39,71,72,73,74,75 , while studies in rodents demonstrate anxiolytic actions of PVN and SON OT pathways within amygdala networks 33,35,76 .”
Differential effects of central oxytocin on social versus cued fear in male rodents
Toth, I. (2014) · University of Regensburg Publication Server (University of Regensburg) · doi:10.5283/epub.27841
Linnen, A. (2011) · Spectrum Research Repository (Concordia University)
Metadata
- Authors
- Gamer, M., Zurowski, B., & Büchel, C.
- Affiliations
- University Medical Center Hamburg-Eppendorf (DE)
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2010-04-26
- Volume
- 107
- Issue
- 20
- Pages
- 9400-9405
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC2889107
- OpenAlex
- W2077718235
- Cited by
- 487
- References
- 53
- Citations by year
- 2026: 6 · 2025: 13 · 2024: 14 · 2023: 16 · 2022: 18 · 2021: 25 · 2020: 38 · 2019: 16 · 2018: 31 · 2017: 40 · 2016: 30 · 2015: 38 · 2014: 43 · 2013: 59 · 2012: 46
- FWCI
- 68.76
- Type
- journal article
- Language
- en
- Update notices
- correction (2011-01-18)
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Bundesministerium für Bildung und Forschung
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Keywords
- oxytocin, amygdala subregions, emotional face processing, valence, attentional bias, gaze shifts, eye movements, superior colliculus, social cognition
- MeSH terms
- Adult, Amygdala, Attention, Double-Blind Method, Emotions, Eye Movements, Face, Germany, Humans, Magnetic Resonance Imaging, Male, Oxytocin, Photic Stimulation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
