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Ancient west Eurasian ancestry in southern and eastern Africa
Open accessAbstract
Significance: The hunter–gatherer and pastoralist populations of southern Africa are among the culturally, linguistically, and genetically most diverse human populations. However, little is known about their history. We show that all of these populations have some ancestry most closely related to Europeans and Middle Easterners and use this to reconstruct the history of population movements between Eurasia, eastern Africa, and southern Africa.
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“These Neanderthal haplotype blocks may have originated in ancient European migrants to eastern Africa (26) and spread beyond eastern Africa through gene flow, which is known to have affected even the basal Africa-MBK lineages (27).”
From An ancestral recombination graph of human, Neanderthal, and Denisovan genomes (2021) · cites this paper as [26]
In the citing paper
“These observations suggest that the population-specific haplotype blocks may be the result of more recent population-specific Neanderthal admixture, as has recently been suggested (26–28, 30).”
From An ancestral recombination graph of human, Neanderthal, and Denisovan genomes (2021) · cites this paper as [26]
In the citing paper
“Migrations from the Near East also occurred towards the southwest into East African populations which experienced West Eurasian admixture ~1,000 BCE31,32.”
From Genomic insights into the origin of farming in the ancient Near East (2016) · cites this paper as [31]
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Metadata
- Authors
- Pickrell, J. K., Patterson, N., Loh, P.-R., Lipson, M., Berger, B., Stoneking, M., Pakendorf, B., & Reich, D.
- Affiliations
- Howard Hughes Medical Institute (US)
- Broad Institute (US)
- Massachusetts Institute of Technology (US)
- Max Planck Society (DE)
- Centre National de la Recherche Scientifique (FR)
- ORCID
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2014-02-03
- Volume
- 111
- Issue
- 7
- Pages
- 2632-2637
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC3932865
- OpenAlex
- W2109211295
- Cited by
- 300
- References
- 29
- Citations by year
- 2026: 10 · 2025: 49 · 2024: 5 · 2023: 16 · 2022: 25 · 2021: 25 · 2020: 29 · 2019: 22 · 2018: 27 · 2017: 21 · 2016: 26 · 2015: 23 · 2014: 21
- FWCI
- 19.92
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- arXiv (Cornell University) (submittedVersion)
- HAL (submittedVersion, other-oa)
- DSpace@MIT (Massachusetts Institute of Technology) (submittedVersion, cc-by-nc)
- Max Planck Digital Library (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- arXiv (Cornell University)
- Funders
- National Science Foundation (1032255)
- Howard Hughes Medical Institute
- Simons Foundation
- European Science Foundation
- Deutsche Forschungsgemeinschaft
- Agence Nationale de la Recherche (ANR-11-IDEX-0007)
- Max-Planck-Gesellschaft
- National Institutes of Health (GM100233)
- National Human Genome Research Institute (T32HG004947)
- National Institute of General Medical Sciences (GM108348, F32GM103098, GM103098, GM100233, R01GM108348, R01GM100233)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Social Sciences › Anthropology › Race, Genetics, and Society
- Keywords
- Southern Africa, East Africa, hunter-gatherers, pastoralists, demographic history, migration routes
- MeSH terms
- Africa, Eastern, Africa, Southern, Computer Simulation, Demography, Emigration and Immigration, Ethnicity, Europe, Gene Frequency, Genetics, Population, Genotype, Humans, Models, Genetic, Linkage Disequilibrium, White People, Gene Flow
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