The Mosaic Genome of Indigenous African Cattle as a Unique Genetic Resource for African Pastoralism
Open accessAbstract
Cattle pastoralism plays a central role in human livelihood in Africa. However, the genetic history of its success remains unknown. Here, through whole-genome sequence analysis of 172 indigenous African cattle from 16 breeds representative of the main cattle groups, we identify a major taurine × indicine cattle admixture event dated to circa 750-1,050 yr ago, which has shaped the genome of today's cattle in the Horn of Africa. We identify 16 loci linked to African environmental adaptations across crossbred animals showing an excess of taurine or indicine ancestry. These include immune-, heat-tolerance- and reproduction-related genes. Moreover, we identify one highly divergent locus in African taurine cattle, which is putatively linked to trypanotolerance and present in crossbred cattle living in trypanosomosis-infested areas. Our findings indicate that a combination of past taurine and recent indicine admixture-derived genetic resources is at the root of the present success of African pastoralism.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Zebu cattle spread westward from the Abyssinian region across the continent and penetrated south to Zambia, forming two major hybrid zones of taurine and zebu cattle in West and Southern Africa.
“Zebu cattle spread westward from the Abyssinian region across the continent and penetrated south to Zambia, forming two major hybrid zones of taurine and zebu cattle in West and Southern Africa [48,49,50].”
From The Genomic Landscape of Cattle: Domestication, Dispersal, and Adaptive Evolution (2026) · cites this paper as [50]
Cites
Trimmomatic: a flexible trimmer for Illumina sequence data
Bolger, A. M., Lohse, M., & Usadel, B. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btu170 · Cited by 65,548 · see citing works
The Sequence Alignment/Map format and SAMtools
Li, H., Handsaker, B., Wysoker, A., Fennell, T., Ruan, J., Homer, N., Marth, G., Abecasis, G., Durbin, R., & 1000 Genome Project Data Processing Subgroup (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp352 · Cited by 62,041 · see citing works
Fast and accurate short read alignment with Burrows-Wheeler transform
Li, H., & Durbin, R. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp324 · Cited by 58,607 · see citing works
PLINK: a tool set for whole-genome association and population-based linkage analyses.
Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A. R., Bender, D., Maller, J., Sklar, P., de Bakker, P. I. W., Daly, M. J., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/519795 · Cited by 34,089 · see citing works
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
McKenna, A., Hanna, M., Banks, E., Sivachenko, A., Cibulskis, K., Kernytsky, A., Garimella, K., Altshuler, D., Gabriel, S., Daly, M., et al. (2010) · Genome Research · doi:10.1101/gr.107524.110 · Cited by 27,895 · see citing works
IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies
Nguyen, L.-T., Schmidt, H. A., von Haeseler, A., & Minh, B. Q. (2015) · Molecular Biology and Evolution · doi:10.1093/molbev/msu300 · Cited by 26,046 · see citing works
Detecting the number of clusters of individuals using the software structure: a simulation study
Evanno, G., Regnaut, S., & Goudet, J. (2005) · Molecular Ecology · doi:10.1111/j.1365-294x.2005.02553.x · Cited by 21,540 · see citing works
ESTIMATING F -STATISTICS FOR THE ANALYSIS OF POPULATION STRUCTURE
Weir, B. S., & Cockerham, C. C. (1984) · Evolution · doi:10.1111/j.1558-5646.1984.tb05657.x · Cited by 18,909 · see citing works
ModelFinder: fast model selection for accurate phylogenetic estimates
Kalyaanamoorthy, S., Minh, B. Q., Wong, T. K. F., von Haeseler, A., & Jermiin, L. S. (2017) · Nature Methods · doi:10.1038/nmeth.4285 · Cited by 18,449 · see citing works
The variant call format and VCFtools
Danecek, P., Auton, A., Abecasis, G. R., Albers, C. A., Banks, E., DePristo, M. A., Handsaker, R. E., Lunter, G. A., Marth, G., Sherry, S. T., et al. (2011) · Bioinformatics · doi:10.1093/bioinformatics/btr330 · Cited by 16,008 · see citing works
Evolutionary trees from DNA sequences: A maximum likelihood approach.
Felsenstein, J. (1981) · Journal of Molecular Evolution · doi:10.1007/bf01734359 · Cited by 14,571 · see citing works
Cingolani, P., Platts, A., Wang, L. L., Coon, M., Nguyen, T., Wang, L., Land, S. J., Lu, X., & Ruden, D. M. (2012) · Fly · doi:10.4161/fly.19695 · Cited by 11,816 · see citing works
Fast model-based estimation of ancestry in unrelated individuals
Alexander, D. H., Novembre, J., & Lange, K. (2009) · Genome Research · doi:10.1101/gr.094052.109 · Cited by 9,898 · see citing works
GCTA: a tool for genome-wide complex trait analysis
Yang, J., Lee, S. H., Goddard, M. E., & Visscher, P. M. (2011) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2010.11.011 · Cited by 8,279 · see citing works
Self-citationBrowning, S. R., & Browning, B. L. (2007) · The American Journal of Human Genetics · doi:10.1086/521987 · Cited by 3,138 · see citing works
Mi, H., Muruganujan, A., Ebert, D., Huang, X., & Thomas, P. D. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky1038 · Cited by 2,950 · see citing works
Ancient Admixture in Human History
Patterson, N., Moorjani, P., Luo, Y., Mallick, S., Rohland, N., Zhan, Y., Genschoreck, T., Webster, T., & Reich, D. (2012) · Genetics · doi:10.1534/genetics.112.145037 · Cited by 2,848 · see citing works
A Map of Recent Positive Selection in the Human Genome
Voight, B. F., Kudaravalli, S., Wen, X., & Pritchard, J. K. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040072 · Cited by 2,847 · see citing works
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
Ishikawa, H., Ma, Z., & Barber, G. N. (2009) · Nature · doi:10.1038/nature08476 · Cited by 2,759 · see citing works
Zerbino, D. R., Achuthan, P., Akanni, W., Amode, M. R., Barrell, D., Bhai, J., Billis, K., Cummins, C., Gall, A., Girón, C. G., et al. (2018) · Nucleic Acids Research · doi:10.1093/nar/gkx1098 · Cited by 2,605 · see citing works
ggmap: Spatial Visualization with ggplot2
Kahle, D. J., & Wickham, H. (2013) · The R Journal · doi:10.32614/rj-2013-014 · Cited by 2,126 · see citing works
GeneCards Version 3: the human gene integrator
Safran, M., Dalah, I., Alexander, J., Rosen, N., Stein, T. I., Shmoish, M., Nativ, N., Bahir, I., Doniger, T., Krug, H., et al. (2010) · Database · doi:10.1093/database/baq020 · Cited by 2,105 · see citing works
The Reactome pathway knowledgebase
Croft, D., Mundo, A. F., Haw, R., Milacic, M., Weiser, J., Wu, G., Caudy, M., Garapati, P., Gillespie, M., Kamdar, M. R., et al. (2014) · Nucleic Acids Research · doi:10.1093/nar/gkt1102 · Cited by 1,889 · see citing works
Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude
Yi, X., Liang, Y., Huerta-Sanchez, E., Jin, X., Cuo, Z. X. P., Pool, J. E., Xu, X., Jiang, H., Vinckenbosch, N., Korneliussen, T. S., et al. (2010) · Science · doi:10.1126/science.1190371 · Cited by 1,611 · see citing works
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
Zhao, Y., Yang, J., Shi, J., Gong, Y., Lu, Q., Xu, H., Liu, L., & Shao, F. (2011) · Nature · doi:10.1038/nature10510 · Cited by 1,273 · see citing works
The Reactome pathway Knowledgebase
Fabregat, A., Sidiropoulos, K., Garapati, P., Gillespie, M., Hausmann, K., Haw, R., Jassal, B., Jupe, S., Korninger, F., McKay, S., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkv1351 · Cited by 1,201 · see citing works
Inference of Population Structure using Dense Haplotype Data
Lawson, D. J., Hellenthal, G., Myers, S., & Falush, D. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002453 · Cited by 1,188 · see citing works
The diversity of the DnaJ/Hsp40 family, the crucial partners for Hsp70 chaperones
Qiu, X., Shao, Y., Miao, S., & Wang, L. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-006-6192-6 · Cited by 900 · see citing works
Evidence for Two Independent Domestications of Cattle
Loftus, R. T., MacHugh, D. E., Bradley, D. G., Sharp, P. M., & Cunningham, P. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.7.2757 · Cited by 812 · see citing works
A genetic atlas of human admixture history
Hellenthal, G., Busby, G. B. J., Band, G., Wilson, J. F., Capelli, C., Falush, D., & Myers, S. (2014) · Science · doi:10.1126/science.1243518 · Cited by 798 · see citing works
Canna, S., de Jesus, A. A., Gouni, S., Brooks, S. R., Marrero, B., Liu, Y., DiMattia, M. A., Zaal, K. J. M., Sanchez, G. A. M., Kim, H., et al. (2014) · Nature Genetics · doi:10.1038/ng.3089 · Cited by 739 · see citing works
Self-citationPhysiological and cellular adaptations of zebu cattle to thermal stress
Hansen, P. J. (2004) · Animal Reproduction Science · doi:10.1016/j.anireprosci.2004.04.011 · Cited by 642 · see citing works
Mitochondrial diversity and the origins of African and European cattle
Bradley, D. G., MacHugh, D. E., Cunningham, P., & Loftus, R. T. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.10.5131 · Cited by 584 · see citing works
African Pastoralism: Genetic Imprints of Origins and Migrations
Hanotte, O., Bradley, D. G., Ochieng, J. W., Verjee, Y., Hill, E. W., & Rege, J. E. O. (2002) · Science · doi:10.1126/science.1069878 · Cited by 567 · see citing works
Self-citationMacHugh, D. E., Shriver, M. D., Loftus, R. T., Cunningham, P., & Bradley, D. G. (1997) · Genetics · doi:10.1093/genetics/146.3.1071 · Cited by 547 · see citing works
Wu, C.-I., & Ting, C.-T. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1269 · Cited by 532 · see citing works
Inferring admixture histories of human populations using linkage disequilibrium
Loh, P.-R., Lipson, M., Patterson, N., Moorjani, P., Pickrell, J. K., Reich, D., & Berger, B. (2013) · Genetics · doi:10.1534/genetics.112.147330 · Cited by 466 · see citing works
(1971) · CGSPace A Repository of Agricultural Research Outputs (Consultative Group for International Agricultural Research) · Cited by 426 · see citing works
Chen, N., Cai, Y., Chen, Q., Li, R., Wang, K., Huang, Y., Hu, S., Huang, S., Zhang, H., Zheng, Z., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04737-0 · Cited by 403 · see citing works
A UAF1-Containing Multisubunit Protein Complex Regulates the Fanconi Anemia Pathway
Cohn, M. A., Kowal, P., Yang, K., Haas, W., Huang, T. T., Gygi, S. P., & D’Andrea, A. D. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.09.031 · Cited by 355 · see citing works
The Origins and Development of African Livestock: Archaeology, Genetics, Linguistics and Ethnography
Blench, R. M., & MacDonald, K. C. (2006) · Medical Entomology and Zoology · Cited by 348 · see citing works
The MAGUK Family Protein CARD11 Is Essential for Lymphocyte Activation
Hara, H., Wada, T., Bakal, C., Kozieradzki, I., Suzuki, S., Suzuki, N., Nghiem, M. P., Griffiths, E. K., Krawczyk, C. M., Bauer, B., et al. (2003) · Immunity · doi:10.1016/s1074-7613(03)00148-1 · Cited by 336 · see citing works
Identification of FAAP24, a Fanconi Anemia Core Complex Protein that Interacts with FANCM
Ciccia, A., Ling, C., Coulthard-Graf, R., Yan, Z., Xue, Y., Meetei, A. R., Laghmani, E. H., Joenje, H., McDonald, N. Q., de Winter, J. P., et al. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.01.003 · Cited by 321 · see citing works
Verhoeven, K. J. F., Macel, M., Wolfe, L. M., & Biere, A. (2010) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2010.1272 · Cited by 309 · see citing works
Ancient west Eurasian ancestry in southern and eastern Africa
Pickrell, J. K., Patterson, N., Loh, P.-R., Lipson, M., Berger, B., Stoneking, M., Pakendorf, B., & Reich, D. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1313787111 · Cited by 300 · see citing works
- Invited Review - African Indigenous Cattle: Unique Genetic Resources in a Rapidly Changing World
Mwai, O., Hanotte, O., Kwon, Y.-J., & Cho, S. (2015) · Asian-Australasian Journal of Animal Sciences · doi:10.5713/ajas.15.0002r · Cited by 300 · see citing works
Self-citationPhysiology and pathophysiology of the vasopressin-regulated renal water reabsorption
Boone, M., & Deen, P. M. T. (2008) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-008-0498-1 · Cited by 291 · see citing works
Mitochondrial Genomes of Extinct Aurochs Survive in Domestic Cattle
Achilli, A., Olivieri, A., Pellecchia, M., Uboldi, C., Colli, L., Al-Zahery, N., Accetturo, M., Pala, M., Kashani, B. H., Perego, U. A., et al. (2008) · Current Biology · doi:10.1016/j.cub.2008.01.019 · Cited by 290 · see citing works
On the Origin of Cattle: How Aurochs Became Cattle and Colonized the World
Ajmone‐Marsan, P., Garcia, J. F., & Lenstra, J. A. (2010) · Evolutionary Anthropology Issues News and Reviews · doi:10.1002/evan.20267 · Cited by 287 · see citing works
An inherited mutation in NLRC4 causes autoinflammation in human and mice
Kitamura, A., Sasaki, Y., Abe, T., Kano, H., & Yasutomo, K. (2014) · The Journal of Experimental Medicine · doi:10.1084/jem.20141091 · Cited by 284 · see citing works
Domesticating animals in Africa: implications of genetic and archaeological findings
Gifford-Gonzalez, D., & Hanotte, O. (2011) · Journal of World Prehistory · doi:10.1007/s10963-010-9042-2 · Cited by 274 · see citing works
Self-citationThe Genome Landscape of Indigenous African Cattle
Kim, J., Hanotte, O., Mwai, O. A., Dessie, T., Bashir, S., Diallo, B., Agaba, M., Kim, K., Kwak, W., Sung, S., et al. (2017) · Genome biology · doi:10.1186/s13059-017-1153-y · Cited by 271 · see citing works
Self-citationBibi, F. (2013) · BMC Evolutionary Biology · doi:10.1186/1471-2148-13-166 · Cited by 265 · see citing works
"Dark" Purkinje cells of the cerebellar cortex.
Leranth, C., & Hámori, J. (1970) · PubMed · Cited by 264 · see citing works
Hanotte, O., Tawah, C. L., Bradley, D. G., Okomo, M., Verjee, Y., Ochieng, J., & Rege, J. E. O. (2000) · Molecular Ecology · doi:10.1046/j.1365-294x.2000.00858.x · Cited by 257 · see citing works
Self-citationMorchikh, M., Cribier, A., Raffel, R., Amraoui, S., Cau, J., Séverac, D., Dubois, E., Schwartz, O., Bennasser, Y., & Benkirane, M. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.06.020 · Cited by 236 · see citing works
Pervasive introgression facilitated domestication and adaptation in the Bos species complex
Wu, D., Ding, X., Wang, S., Wójcik, J. M., Zhang, Y., Tokarska, M., Li, Y., Wang, M.-S., Faruque, O., Nielsen, R., et al. (2018) · Nature Ecology & Evolution · doi:10.1038/s41559-018-0562-y · Cited by 233 · see citing works
Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis
Ma, L., O’Connell, J. R., VanRaden, P. M., Shen, B., Padhi, A., Sun, C., Bickhart, D. M., Cole, J. B., Null, D. J., Liu, G. E., et al. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005387 · Cited by 232 · see citing works
Park, S. D. E., Magee, D. A., McGettigan, P., Teasdale, M. D., Edwards, C. J., Lohan, A. J., Murphy, A., Braud, M., Donoghue, M. T. A., Liu, Y., et al. (2015) · Genome biology · doi:10.1186/s13059-015-0790-2 · Cited by 228 · see citing works
Genetics of adaptation in domestic farm animals: A review
Mirkena, T., Duguma, G., Haile, A., Tibbo, M., Okeyo, A. M., Wurzinger, M., & Sölkner, J. (2010) · Livestock Science · doi:10.1016/j.livsci.2010.05.003 · Cited by 214 · see citing works
CARD11 mediates factor‐specific activation of NF‐κB by the T cell receptor complex
Pomerantz, J. L., Denny, E. M., & Baltimore, D. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf505 · Cited by 211 · see citing works
Hanotte, O., Ronin, Y. I., Agaba, M. K., Nilsson, P. R., Gelhaus, A., Horstmann, R., Sugimoto, Y., Kemp, S. J., Gibson, J. P., Korol, A. B., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1232392100 · Cited by 196 · see citing works
Self-citationA whole genome Bayesian scan for adaptive genetic divergence in West African cattle
Gautier, M., Flori, L., Riebler, A., Jaffrézic, F., Laloë, D., Gut, I. G., Moazami‐Goudarzi, K., & Foulley, J. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-550 · Cited by 196 · see citing works
Hovick, S. M., & Whitney, K. D. (2014) · Ecology Letters · doi:10.1111/ele.12355 · Cited by 193 · see citing works
Animal Disease Challenges to the Emergence of Pastoralism in Sub-Saharan Africa
Gifford-Gonzalez, D. P. (2000) · African Archaeological Review · doi:10.1023/a:1006601020217 · Cited by 183 · see citing works
The Peopling of Africa: A Geographic Interpretation.
McCall, D. F., & Newman, J. L. (1996) · The American Historical Review · doi:10.2307/2170286 · Cited by 150 · see citing works
Genomic divergence of zebu and taurine cattle identified through high-density SNP genotyping
Neto, L. R. P., Sonstegard, T. S., Liu, G. E., Bickhart, D. M., Silva, M. V. D., Machado, M. A., Utsunomiya, Y. T., Garcia, J. F., Gondro, C., & Tassell, C. P. V. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-876 · Cited by 146 · see citing works
TMEM173 variants and potential importance to human biology and disease
Patel, S., & Jin, L. (2018) · Genes and Immunity · doi:10.1038/s41435-018-0029-9 · Cited by 139 · see citing works
Mason's world encyclopedia of livestock breeds and breeding. Volume 1 and Volume 2
(2016) · CABI eBooks · doi:10.1079/9781845934668.0000 · Cited by 136 · see citing works
Međugorac, I., Graf, A., Grohs, C., Rothammer, S., Zagdsuren, Y., Александровна, Г. Е., Zinovieva, N. A., Barbieri, J., Seichter, D., Ruß, I., et al. (2017) · Nature Genetics · doi:10.1038/ng.3775 · Cited by 129 · see citing works
Inside the “African Cattle Complex”: Animal Burials in the Holocene Central Sahara
di Lernia, S., Tafuri, M. A., Gallinaro, M., Alhaique, F., Balasse, M., Cavorsi, L., Fullagar, P. D., Mercuri, A. M., Monaco, A. L., Perego, A., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056879 · Cited by 128 · see citing works
Genomic clues of the evolutionary history of <i>Bos indicus</i> cattle
Utsunomiya, Y. T., Milanesi, M., Fortes, M. R. S., Porto‐Neto, L. R., Utsunomiya, A. T. H., Silva, M. V. G. B., Garcia, J. F., & Ajmone‐Marsan, P. (2019) · Animal Genetics · doi:10.1111/age.12836 · Cited by 128 · see citing works
Genome-Wide Scan for Selection Signatures in Six Cattle Breeds in South Africa
Makina, S. O., Muchadeyi, F. C., van Marle-Köster, E., Taylor, J. F., Makgahlela, M. L., & Maiwashe, A. (2015) · Genetics Selection Evolution · doi:10.1186/s12711-015-0173-x · Cited by 125 · see citing works
Loter: A Software Package to Infer Local Ancestry for a Wide Range of Species
Alves, T. D., Mairal, J., & Blum, M. G. B. (2018) · Molecular Biology and Evolution · doi:10.1093/molbev/msy126 · Cited by 123 · see citing works
Genome Sequence and Assembly of Bos indicus
Canavez, F., Luche, D. D., Stothard, P., Leite, K. R. M., de Sousa-Canavez, J. M., Plastow, G. S., Meidânis, J., Souza, M. A., Feijão, P., Moore, S. S., et al. (2012) · Journal of Heredity · doi:10.1093/jhered/esr153 · Cited by 120 · see citing works
Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function
Kumar, L., Chou, J. S., Yee, C. S. K., Borzutzky, A., Vollmann, E. H., von Andrian, U. H., Park, S., Holländer, G. A., Manis, J. P., Poliani, P. L., et al. (2014) · The Journal of Experimental Medicine · doi:10.1084/jem.20131379 · Cited by 120 · see citing works
Flach, H., Rosenbaum, M., Duchniewicz, M., Kim, S., Zhang, S. L., Cahalan, M. D., Mittler, G., & Grosschedl, R. (2010) · Immunity · doi:10.1016/j.immuni.2010.11.013 · Cited by 118 · see citing works
Bahbahani, H. M., Clifford, H., Wragg, D., Mbole-Kariuki, M. N., Tassell, C. P. V., Sonstegard, T. S., Woolhouse, M. E. J., & Hanotte, O. (2015) · Scientific Reports · doi:10.1038/srep11729 · Cited by 110 · see citing works
Self-citationAdmixture and diversity in West African cattle populations
Freeman, A., Meghen, C., MacHugh, D., Loftus, R., Achukwi, M. D., Bado, A., Sauveroche, B., & Bradley, D. (2004) · Molecular Ecology · doi:10.1111/j.1365-294x.2004.02311.x · Cited by 108 · see citing works
The advent of herding in the Horn of Africa: New data from Ethiopia, Djibouti and Somaliland
Lesur, J., Hildebrand, E., Abawa, G., & Gutherz, X. (2013) · Quaternary International · doi:10.1016/j.quaint.2013.11.024 · Cited by 107 · see citing works
Origin and Spread of Bos taurus: New Clues from Mitochondrial Genomes Belonging to Haplogroup T1
Bonfiglio, S., Ginja, C., De Gaetano, A., Achilli, A., Olivieri, A., Colli, L., Tesfaye, K., Agha, S. H., Gama, L. T., Cattonaro, F., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038601 · Cited by 106 · see citing works
MacEachern, S., Hayes, B. J., McEwan, J. C., & Goddard, M. E. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-181 · Cited by 103 · see citing works
Indian Ocean Food Globalisation and Africa
Boivin, N. L., Crowther, A., Prendergast, M. E., & Fuller, D. Q. (2014) · African Archaeological Review · doi:10.1007/s10437-014-9173-4 · Cited by 103 · see citing works
On the Breeds of Cattle—Historic and Current Classifications
Felius, M., Koolmees, P. A., Theunissen, B., & Lenstra, J. A. (2011) · Diversity · doi:10.3390/d3040660 · Cited by 102 · see citing works
Genetic Resistance to African Trypanosomiasis
Murray, M., Trail, J. C. M., Davis, C. E. L. B., & Black, S. J. (1984) · The Journal of Infectious Diseases · doi:10.1093/infdis/149.3.311 · Cited by 99 · see citing works
ATG4B (Autophagin-1) Phosphorylation Modulates Autophagy
Yang, Z., Wilkie-Grantham, R. P., Yanagi, T., Shu, C., Matsuzawa, S., & Reed, J. C. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.658088 · Cited by 96 · see citing works
Russell, J. M., Verschuren, D., & Eggermont, H. (2007) · The Holocene · doi:10.1177/0959683607075832 · Cited by 90 · see citing works
Bahbahani, H. M., Tijjani, A., Mukasa, C., Wragg, D., Almathen, F. S., Nash, O., Akpa, G. N., Mbole-Kariuki, M. N., Malla, S., Woolhouse, M. E. J., et al. (2017) · Frontiers in Genetics · doi:10.3389/fgene.2017.00068 · Cited by 89 · see citing works
Self-citationRoberts, C. J., & Gray, A. R. (1973) · Tropical Animal Health and Production · doi:10.1007/bf02240423 · Cited by 88 · see citing works
Cecchi, G., Paone, M., Argilés-Herrero, R., Vreysen, M. J. B., & Mattioli, R. C. (2015) · Parasites & Vectors · doi:10.1186/s13071-015-0898-y · Cited by 88 · see citing works
Adaptive admixture in the W est A frican bovine hybrid zone: insight from the B orgou population
Flori, L., Thévenon, S., Dayo, G., Sènou, M., Sylla, S., Berthier, D., Moazami‐Goudarzi, K., & Gautier, M. (2014) · Molecular Ecology · doi:10.1111/mec.12816 · Cited by 88 · see citing works
Noyes, H., Brass, A., Obara, I., Anderson, S., Archibald, A. L., Bradley, D. G., Fisher, P., Freeman, A., Gibson, J., Gicheru, M., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1013486108 · Cited by 88 · see citing works
Self-citationRege, J. E. O., Kahi, A. K., Okomo‐Adhiambo, M., Mwacharo, J. M., & Hanotte, O. (2001) · CGSPace A Repository of Agricultural Research Outputs (Consultative Group for International Agricultural Research) · Cited by 86 · see citing works
Self-citationMcElroy, A. K., & Nichol, S. T. (2011) · Virology · doi:10.1016/j.virol.2011.09.023 · Cited by 85 · see citing works
MacLean, C., Hong, N. C., & Prendergast, J. G. D. (2015) · Molecular Biology and Evolution · doi:10.1093/molbev/msv172 · Cited by 84 · see citing works
“Animal disease challenges” fifteen years later: The hypothesis in light of new data
Gifford-Gonzalez, D. P. (2016) · Quaternary International · doi:10.1016/j.quaint.2015.10.054 · Cited by 84 · see citing works
The Origins and Development of African Livestock
Blench, R. M., & MacDonald, K. C. (2006) · Routledge eBooks · doi:10.4324/9780203984239 · Cited by 81 · see citing works
EPIDEMICS AND REVOLUTIONS: THE RINDERPEST EPIDEMIC IN LATE NINETEENTH–CENTURY SOUTHERN AFRICA
Phoofolo, P. (1993) · Past & Present · doi:10.1093/past/138.1.112 · Cited by 80 · see citing works
Host genetics in African trypanosomiasis
Courtin, D., Berthier, D., Thévenon, S., Dayo, G., Garcia, A., & Bucheton, B. (2008) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2008.02.007 · Cited by 78 · see citing works
Towards a new phenotype for tick resistance in beef and dairy cattle: a review
Burrow, H. M., Mans, B. J., Cardoso, F. F., Birkett, M. A., Kotze, A. C., Hayes, B. J., Mapholi, N. O., Dzama, K., Marufu, M. C., Githaka, N., et al. (2019) · Animal Production Science · doi:10.1071/an18487 · Cited by 74 · see citing works
Tijjani, A., Utsunomiya, Y. T., Ezekwe, A. G., Nashiru, O., & Hanotte, O. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00442 · Cited by 72 · see citing works
Self-citationToward the identification of a subset of unexplained infertility: a sperm proteomic approach
McReynolds, S., Dzieciątkowska, M., Stevens, J., Hansen, K. C., Schoolcraft, W. B., & Katz‐Jaffe, M. G. (2014) · Fertility and Sterility · doi:10.1016/j.fertnstert.2014.05.021 · Cited by 71 · see citing works
Kuo, Y., Shen, Y.-R., Chen, H.-I., Lin, Y., Wang, Y., Chen, Y., Wang, C., & Kuo, P. (2015) · Journal of Cell Science · doi:10.1242/jcs.158998 · Cited by 69 · see citing works
Identification of mechanisms of natural resistance to African trypanosomiasis in cattle
Naessens, J., Teale, A. J., & Sileghem, M. (2002) · Veterinary Immunology and Immunopathology · doi:10.1016/s0165-2427(02)00070-3 · Cited by 69 · see citing works
Mbole-Kariuki, M. N., Sonstegard, T., Orth, A., Thumbi, S. M., Bronsvoort, B. M. D. C., Kiara, H., Toye, P., Conradie, I., Jennings, A., Coetzer, K., et al. (2014) · Heredity · doi:10.1038/hdy.2014.31 · Cited by 69 · see citing works
Self-citationSignatures of positive selection in African Butana and Kenana dairy zebu cattle
Bahbahani, H., Salim, B., Almathen, F., Al Enezi, F., Mwacharo, J. M., & Hanotte, O. (2018) · PLOS ONE · doi:10.1371/journal.pone.0190446 · Cited by 67 · see citing works
Self-citationEarly herders and monumental sites in eastern Africa: dating and interpretation
Hildebrand, E., & Grillo, K. M. (2012) · Antiquity · doi:10.1017/s0003598x00062803 · Cited by 66 · see citing works
Koufariotis, L. T., Hayes, B. J., Kelly, M., Burns, B. M., Lyons, R. E., Stothard, P., Chamberlain, A. J., & Moore, S. S. (2018) · Scientific Reports · doi:10.1038/s41598-018-35698-5 · Cited by 66 · see citing works
Y‐specific microsatellites reveal an African subfamily in taurine (<i>Bos taurus</i>) cattle
Pérez‐Pardal, L., Royo, L. J., Beja‐Pereira, A., Curik, I., Traoré, A., Fernández, I., Sölkner, J., Alonso, J., Álvarez, I., Bozzi, R., et al. (2010) · Animal Genetics · doi:10.1111/j.1365-2052.2009.01988.x · Cited by 61 · see citing works
Climate, ecology, and the spread of herding in eastern Africa
Chritz, K. L., Cerling, T. E., Freeman, K. H., Hildebrand, E., Janzen, A., & Prendergast, M. E. (2018) · Quaternary Science Reviews · doi:10.1016/j.quascirev.2018.11.029 · Cited by 52 · see citing works
Shin, D., Lee, H. J., Cho, S., Kim, H. J., Hwang, J. Y., Lee, C., Jeong, J., Yoon, D., & Kim, H. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-240 · Cited by 51 · see citing works
Self-citationBall, E. A., Sambo, M. D. R., Martins, M., Trovoada, M. J., Benchimol, C., Costa, J., Gonçalves, L. A., Coutinho, A., & Penha‐Gonçalves, C. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300114 · Cited by 48 · see citing works
Wang, X., Shaw, D. K., Sakhon, O. S., Snyder, G. A., Sundberg, E. J., Santambrogio, L., Sutterwala, F. S., Dumler, J. S., Shirey, K. A., Perkins, D. J., et al. (2016) · Infection and Immunity · doi:10.1128/iai.01526-15 · Cited by 48 · see citing works
Inferring Heterozygosity from Ancient and Low Coverage Genomes
Kousathanas, A., Leuenberger, C., Link, V., Sell, C., Bürger, J., & Wegmann, D. (2016) · Genetics · doi:10.1534/genetics.116.189985 · Cited by 48 · see citing works
Lemecha, H., Mulatu, W., Hussein, I., Rege, E., Tekle, T., Abdicho, S., & Ayalew, W. (2006) · Veterinary Parasitology · doi:10.1016/j.vetpar.2006.04.035 · Cited by 47 · see citing works
Deciphering the Genetic Blueprint behind Holstein Milk Proteins and Production
Lee, H. J., Kim, J., Lee, T., Son, J.-K., Yoon, H., Baek, K., Jeong, J. Y., Cho, Y.-M., Lee, K., Yang, B., et al. (2014) · Genome Biology and Evolution · doi:10.1093/gbe/evu102 · Cited by 46 · see citing works
Self-citationTrypanosomosis: potential driver of selection in African cattle
Smetko, A., Soudré, A., Silbermayr, K., Müller, S., Brem, G., Hanotte, O., Boettcher, P. J., Stella, A., Mészáros, G., Wurzinger, M., et al. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00137 · Cited by 44 · see citing works
Self-citationHeaton, M. P., Smith, T. P. L., Carnahan, J. K., Basnayake, V. R., Qiu, J., Simpson, B., & Kalbfleisch, T. (2016) · F1000Research · doi:10.12688/f1000research.9254.2 · Cited by 38 · see citing works
Bahbahani, H. M., Afana, A., & Wragg, D. (2018) · PLoS ONE · doi:10.1371/journal.pone.0202479 · Cited by 37 · see citing works
O’Brien, A. M. P., Holler, D. A., Boison, S. A., Milanesi, M., Bomba, L., Utsunomiya, Y. T., Carvalheiro, R., Neves, H. H. D. R., Silva, M. V. D., Vantassell, C. P., et al. (2015) · Genetics Selection Evolution · doi:10.1186/s12711-015-0109-5 · Cited by 34 · see citing works
A Model of African Indigenous Economy and Society
Schneider, H. K. (1964) · Comparative Studies in Society and History · doi:10.1017/s0010417500003443 · Cited by 33 · see citing works
Smedley, D. P., Schofield, P. N., Chen, C.-K., Aidinis, V., Ainali, C., Bard, J., Balling, R., Birney, E., Blake, A., Bongcam‐Rudloff, E., et al. (2010) · Database · doi:10.1093/database/baq014 · Cited by 31 · see citing works
Domesticating Animals in Africa
Gifford-Gonzalez, D. P., & Hanotte, O. (2013) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780199569885.013.0034 · Cited by 30 · see citing works
Self-citationLessons for livestock genomics from genome and transcriptome sequencing in cattle and other mammals
Taylor, J. F., Whitacre, L. K., Hoff, J. L., Tizioto, P. C., Kim, J., Decker, J. E., & Schnabel, R. D. (2016) · Genetics Selection Evolution · doi:10.1186/s12711-016-0237-6 · Cited by 30 · see citing works
Self-citationHeaton, M. P., Smith, T. P. L., Carnahan, J. K., Basnayake, V. R., Qiu, J., Simpson, B., & Kalbfleisch, T. (2016) · F1000Research · doi:10.12688/f1000research.9254.1 · Cited by 28 · see citing works
Sodhi, M., Mukesh, M., Mishra, B., Ahlawat, S., Prakash, B., & Sobti, R. C. (2011) · Animal Biotechnology · doi:10.1080/10495398.2011.536091 · Cited by 22 · see citing works
Tarekegn, G. M., Ji, X., Bai, X., Liu, B., Zhang, W., Birungi, J., Djikeng, A., & Tesfaye, K. (2018) · Asian-Australasian Journal of Animal Sciences · doi:10.5713/ajas.17.0596 · Cited by 22 · see citing works
Self-citationYamada, S., Konnai, S., Imamura, S., Simuunza, M. C., Chembensofu, M., Chota, A., Nambota, A. M., Onuma, M., & Ohashi, K. (2009) · Journal of Veterinary Medical Science · doi:10.1292/jvms.71.49 · Cited by 19 · see citing works
The Archaeology of Herding in Southernmost Africa
Sadr, K. (2013) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780199569885.013.0044 · Cited by 19 · see citing works
The Bos taurus–Bos indicus balance in fertility and milk related genes
Kasarapu, P., Neto, L. R. P., Fortes, M. R. S., Lehnert, S. A., Mudadu, M. A., Coutinho, L. L., Regitano, L. C. D. A., George, A. W., & Reverter, A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0181930 · Cited by 16 · see citing works
Delbès, G., Yanagiya, A., Sonenberg, N., & Robaire, B. (2009) · Biology of Reproduction · doi:10.1093/biolreprod/81.s1.167 · Cited by 3 · see citing works
Flagged first, then by citations
4 of the 135 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Novel Functional Sequences Uncovered through a Bovine Multiassembly Graph
Crysnanto, D., Leonard, A. S., Fang, Z.-H., & Pausch, H. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2101056118 · Cited by 96 · see citing works
Zhou, Y., Yang, L., Han, X., Han, J., Hu, Y., Li, F., Xia, H., Peng, L., Boschiero, C., Rosen, B. D., et al. (2022) · Genome Research · doi:10.1101/gr.276550.122 · Cited by 89 · see citing works
Chen, N., Xia, X., Hanif, Q., Zhang, F., Dang, R., Huang, B., Lyu, Y., Luo, X., Zhang, H., Yan, H., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-43626-z · Cited by 83 · see citing works
Self-citationLeonard, A. S., Crysnanto, D., Fang, Z., Heaton, M. P., Ley, B. L. V., Herrera, C., Bollwein, H., Bickhart, D. M., Kuhn, K. L., Smith, T. P. L., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-30680-2 · Cited by 76 · see citing works
Pangenome graphs and their applications in biodiversity genomics
Secomandi, S., Gallo, G. R., Rossi, R., Fernandes, C., Jarvis, E. D., Bonisoli‐Alquati, A., Gianfranceschi, L., & Formenti, G. (2025) · Nature Genetics · doi:10.1038/s41588-024-02029-6 · Cited by 74 · see citing works
The Quest for Genes Involved in Adaptation to Climate Change in Ruminant Livestock
Passamonti, M. M., Somenzi, E., Barbato, M., Chillemi, G., Colli, L., Joost, S., Milanesi, M., Negrini, R., Santini, M., Vajana, E., et al. (2021) · Animals · doi:10.3390/ani11102833 · Cited by 60 · see citing works
Genetic Improvement of Local Cattle Breeds in West Africa: A Review of Breeding Programs
Ouédraogo, D., Soudré, A., Yougbaré, B., Ouédraogo‐Koné, S., Zoma‐Traoré, B., Khayatzadeh, N., Traoré, A., Sanou, M., Mészáros, G., Burger, P. A., et al. (2021) · Sustainability · doi:10.3390/su13042125 · Cited by 45 · see citing works
Self-citationGlobal dispersal and adaptive evolution of domestic cattle: a genomic perspective
Xia, X., Qu, K., Wang, Y., Sinding, M. S., Wang, F., Hanif, Q., Ahmed, Z., Lenstra, J. A., Han, J., Lei, C., et al. (2023) · Stress Biology · doi:10.1007/s44154-023-00085-2 · Cited by 48 · see citing works
Dai, X., Bian, P., Hu, D., Luo, F., Huang, Y., Jiao, S., Wang, X., Gong, M., Li, R., Cai, Y., et al. (2023) · Genome Research · doi:10.1101/gr.277481.122 · Cited by 43 · see citing works
Ward, J. A., McHugo, G. P., Dover, M. J., Hall, T. J., Ng’ang’a, S. I., Sonstegard, T. S., Bradley, D. G., Frantz, L., Salter‐Townshend, M., & MacHugh, D. E. (2022) · iScience · doi:10.1016/j.isci.2022.104672 · Cited by 45 · see citing works
Mrode, R., Ojango, J. M. K., Ekine-Dzivenu, C. C., Aliloo, H., Gibson, J. P., & Okeyo, M. A. (2021) · Journal of Dairy Science · doi:10.3168/jds.2020-20052 · Cited by 40 · see citing works
Čubrić-Ćurik, V., Novosel, D., Brajković, V., Rota‐Stabelli, O., Krebs, S., Sölkner, J., Šalamon, D., Ristov, S., Berger, B., Trivizaki, S., et al. (2021) · Evolutionary Applications · doi:10.1111/eva.13315 · Cited by 40 · see citing works
Vanvanhossou, S. F. U., Dossa, L. H., & König, S. (2021) · Sustainability · doi:10.3390/su13179874 · Cited by 35 · see citing works
Genomic signatures for drylands adaptation at gene-rich regions in African zebu cattle
Tijjani, A., Salim, B., da Silva, M. V. B., Eltahir, H. A., Musa, T. H., Marshall, K., Hanotte, O., & Musa, H. H. (2022) · Genomics · doi:10.1016/j.ygeno.2022.110423 · Cited by 41 · see citing works
Self-citationGenomic adaptation of Ethiopian indigenous cattle to high altitude
Terefe, E., Belay, G., Han, J., Hanotte, O., & Tijjani, A. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.960234 · Cited by 36 · see citing works
Self-citationPopulation differentiated copy number variation of Bos taurus, Bos indicus and their African hybrids
Jang, J., Terefe, E., Kim, K., Lee, Y. H., Belay, G., Tijjani, A., Han, J., Hanotte, O., & Kim, H. (2021) · BMC Genomics · doi:10.1186/s12864-021-07808-7 · Cited by 33 · see citing works
Self-citationCampbell, M. C., & Ranciaro, A. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddab027 · Cited by 32 · see citing works
Goyache, F., Pérez-Pardal, L., Fernández, I., Traoré, A., Menéndez‐Arias, N. A., & Álvarez, I. (2021) · Gene · doi:10.1016/j.gene.2021.145899 · Cited by 28 · see citing works
Kambal, S., Tijjani, A., Ibrahim, S. A. E., Ahmed, M. A., Mwacharo, J. M., & Hanotte, O. (2023) · Animal Genetics · doi:10.1111/age.13353 · Cited by 27 · see citing works
Self-citationNatural adaptation and human selection of northeast African sheep genomes
Ahbara, A., Musa, H. H., Robert, C., Abebe, A., Al-Jumaili, A. S., Kebede, A., Latairish, S., Agoub, M. O., Clark, E. L., Hanotte, O., et al. (2022) · Genomics · doi:10.1016/j.ygeno.2022.110448 · Cited by 27 · see citing works
Self-citationSipiczki, M. (2022) · Molecular Ecology Resources · doi:10.1111/1755-0998.13586 · Cited by 25 · see citing works
Inference of Admixture Origins in Indigenous African Cattle
Kim, K., Kim, D., Hanotte, O., Lee, C., Kim, H., & Jeong, C. (2023) · Molecular Biology and Evolution · doi:10.1093/molbev/msad257 · Cited by 24 · see citing works
Self-citationMitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle
Kwon, T., Kim, K., Caetano-Anollés, K., Sung, S., Cho, S., Jeong, C., Hanotte, O., & Kim, H. (2022) · BMC Biology · doi:10.1186/s12915-021-01206-x · Cited by 23 · see citing works
Self-citationWhole genome sequencing of simmental cattle for SNP and CNV discovery
Sun, T., Pei, S., Liu, Y., Hanif, Q., Xu, H., Chen, N., Lei, C., & Yue, X. (2023) · BMC Genomics · doi:10.1186/s12864-023-09248-x · Cited by 23 · see citing works
Whole Genome Sequencing Reveals Signals of Adaptive Admixture in Creole Cattle
Ben-Jemaa, S., Adam, G., Boussaha, M., Bardou, P., Klopp, C., Mandonnet, N., & Naves, M. (2023) · Scientific Reports · doi:10.1038/s41598-023-38774-7 · Cited by 22 · see citing works
Terefe, E., Belay, G., Tijjani, A., Han, J., & Hanotte, O. (2023) · Diversity · doi:10.3390/d15040540 · Cited by 21 · see citing works
Self-citationAdaptation of the White Fulani cattle to the tropical environment
Oke, O. E., Oso, O. M., Logunleko, M. O., Uyanga, V. A., Akinyemi, F., Okeniyi, F. A., Akosile, O. A., Baloyi, J. J., & Onagbesan, O. M. (2022) · Journal of Thermal Biology · doi:10.1016/j.jtherbio.2022.103372 · Cited by 21 · see citing works
Genomic characterization of animal genetic resources
Boitard, S., Chikhi, L., da Fonseca, R. R., Ginja, C., Kantanen, J., Lenstra, J. A., Orozco‐terWengel, P., & Pausch, H. (2023) · FAO eBooks · doi:10.4060/cc3079en · Cited by 24 · see citing works
BoLA-DRB3 gene haplotypes show divergence in native Sudanese cattle from taurine and indicine breeds
Salim, B., Takeshima, S., Nakao, R., Moustafa, M. A. M., Ahmed, M. A., Kambal, S., Mwacharo, J. M., Alkhaibari, A. M., & Giovambattista, G. (2021) · Scientific Reports · doi:10.1038/s41598-021-96330-7 · Cited by 20 · see citing works
Self-citationVanvanhossou, S. F. U., Yin, T., Scheper, C., Fries, R., Dossa, L. H., & König, S. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.657282 · Cited by 19 · see citing works
Ouédraogo, D., Ouédraogo‐Koné, S., Yougbaré, B., Soudré, A., Zoma‐Traoré, B., Mészáros, G., Khayatzadeh, N., Traoré, A., Sanou, M., Mwai, O. A., et al. (2021) · Journal of Animal Breeding and Genetics · doi:10.1111/jbg.12529 · Cited by 19 · see citing works
Self-citationBeef Cattle Genome Project: Advances in Genome Sequencing, Assembly, and Functional Genes Discovery
Gao, Z., Lu, Y., Chong, Y., Li, M., Hong, J., Wu, J., Wu, D., Xi, D., & Deng, W. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137147 · Cited by 18 · see citing works
Genomic Diversity and Selection Signatures for Weining Cattle on the Border of Yunnan-Guizhou
Liu, Y., Cheng, H., Wang, S., Luo, X., Ma, X., Sun, L., Chen, N., Zhang, J., Qu, K., Wang, M., et al. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.848951 · Cited by 18 · see citing works
Genomic Insights into the Population History and Adaptive Traits of Latin American Criollo Cattle
Ward, J. A., Ng'ang'a, S. I., Randhawa, I. A. S., McHugo, G. P., O'Grady, J. F., Flórez, J. M., Browne, J. A., Pérez O’Brien, A. M., Landaeta-Hernández, A. J., Garcia, J. F., et al. (2024) · Royal Society Open Science · doi:10.1098/rsos.231388 · Cited by 17 · see citing works
Collagen fingerprinting traces the introduction of caprines to island Eastern Africa
Culley, C., Janzen, A., Brown, S., Prendergast, M. E., Wolfhagen, J., Bourhane, A., Ali, A. K., Haji, O. N., Horton, M., Shipton, C., et al. (2021) · Royal Society Open Science · doi:10.1098/rsos.202341 · Cited by 17 · see citing works
Mauki, D. H., Tijjani, A., Ma, C., Ng’ang’a, S. I., Mark, A. I., Sanke, O. J., Abdussamad, A. M., Olaogun, S. C., Ibrahim, J., Dawuda, P. M., et al. (2022) · BMC Genomics · doi:10.1186/s12864-022-08512-w · Cited by 18 · see citing works
Self-citationAyalew, W., Xiaoyun, W., Tarekegn, G. M., Tessema, T. S., Chu, M., Liang, C., Naboulsi, R., Van Damme, R., Bongcam-Rudloff, E., & Ping, Y. (2024) · BMC Genomics · doi:10.1186/s12864-024-10936-5 · Cited by 15 · see citing works
Self-citationDai, S., Zhao, P., Li, W., Peng, L., Jiang, E., Du, Y., Zhang, W., Dai, X., Yang, L., Li, Z., et al. (2025) · Molecular Biology and Evolution · doi:10.1093/molbev/msaf205 · Cited by 15 · see citing works
Akinsola, O. M., Musa, A. A., Muansangi, L., Singh, S. P., Mukherjee, S., & Mukherjee, A. (2024) · Frontiers in Genetics · doi:10.3389/fgene.2024.1430291 · Cited by 15 · see citing works
Genetic variation of Nigerian cattle inferred from maternal and paternal genetic markers
Mauki, D. H., Adeola, A. C., Ng’ang’a, S. I., Tijjani, A., Akanbi, I. M., Sanke, O. J., Abdussamad, A. M., Olaogun, S. C., Ibrahim, J., Dawuda, P. M., et al. (2021) · PeerJ · doi:10.7717/peerj.10607 · Cited by 15 · see citing works
Self-citationAssessing Genomic Diversity and Productivity Signatures in Dianzhong Cattle by Whole-Genome Scanning
Zhang, X., Qu, K., Jia, P., Zhang, J., Liu, J., Lei, C., & Huang, B. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.719215 · Cited by 14 · see citing works
Whole Genome Scan Uncovers Candidate Genes Related to Milk Production Traits in Barka Cattle
Ayalew, W., Wu, X., Tarekegn, G. M., Tessema, T. S., Naboulsi, R., Damme, R. V., Bongcam‐Rudloff, E., Edea, Z., Chu, M., Enquahone, S., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25116142 · Cited by 12 · see citing works
Self-citationSelection Increases Mitonuclear DNA Discordance but Reconciles Incompatibility in African Cattle
Shi, X., Ma, C., Chen, N., Xu, M., Kambal, S., Cai, Z., Yang, Q., Adeola, A. C., Liu, L.-S., Wang, J., et al. (2025) · Molecular Biology and Evolution · doi:10.1093/molbev/msaf039 · Cited by 12 · see citing works
Self-citationSolodneva, E. V., Svishcheva, G. R., Smolnikov, R., Bazhenov, S., Konorov, E. A., Mukhina, V., & Stolpovsky, Y. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24055061 · Cited by 12 · see citing works
Gao, S., Zheng, Z., Hu, H., Jiang, Y., Liu, M., Stiller, J., Zhou, M., & Liu, C. (2020) · The Crop Journal · doi:10.1016/j.cj.2020.03.008 · Cited by 12 · see citing works
Ancient Genomes Illuminate the Origins and Dynamic History of East Asian Cattle
Cai, D., Kim, D., Zhang, N., Wang, X., Li, T., Li, J., Li, C., Lian, S., Shao, X., Hu, S., et al. (2025) · Science · doi:10.1126/science.adu9904 · Cited by 11 · see citing works
Self-citationFriedrich, J., Liu, S., Fang, L., Prendergast, J. G. D., & Wiener, P. (2024) · BMC Genomics · doi:10.1186/s12864-024-10852-8 · Cited by 11 · see citing works
Chen, Q., Xu, L., Zhang, M., Zhang, T., Yan, M., Zhai, M., & Huang, X. (2022) · Gene · doi:10.1016/j.gene.2022.146725 · Cited by 11 · see citing works
Zegeye, T., Belay, G., Vallejo‐Trujillo, A., Han, J., & Hanotte, O. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1050365 · Cited by 10 · see citing works
Self-citationLee, S., Clémentine, C., & Kim, H. (2024) · Scientific Reports · doi:10.1038/s41598-024-52606-2 · Cited by 10 · see citing works
Self-citationGenomic Reference Resource for African Cattle: Genome Sequences and High-Density Array Variants
Tijjani, A., Kambal, S., Terefe, E., Njeru, R., Ogugo, M., Ndambuki, G., Missohou, A., Traoré, A., Salim, B., Ezeasor, C., et al. (2024) · Scientific Data · doi:10.1038/s41597-024-03589-2 · Cited by 10 · see citing works
Self-citationGenomic characterization of dryland adaptation in endangered Anxi cattle in China
Lyu, Y., Yao, T., Chen, Z., Huangfu, R., Cheng, H., Ma, W., Qi, X., Li, F., Chen, N., & Lei, C. (2024) · Animal Genetics · doi:10.1111/age.13416 · Cited by 9 · see citing works
Oke, O. E., Akosile, O. A., Oliyide, K. M., Ibigbami, D. J., Adeniran, D. A., Oni, A. I., Opowoye, I. O., & Oluwatosin, B. O. (2025) · Journal of Applied Animal Research · doi:10.1080/09712119.2025.2568562 · Cited by 9 · see citing works
Identification and Characterization of Copy Number Variations Regions in West African Taurine Cattle
Goyache, F., Pérez-Pardal, L., Fernández, I., Traoré, A., Menéndez‐Arias, N. A., Arias, K. D., & Álvarez, I. (2022) · Animals · doi:10.3390/ani12162130 · Cited by 9 · see citing works
Xu, L., Zhou, K., Huang, X., Chen, H., Dong, H., & Chen, Q. (2024) · BMC Genomics · doi:10.1186/s12864-024-10084-w · Cited by 8 · see citing works
Si, J., Dai, D., Gorkhali, N. A., Wang, M., Wang, S., Sapkota, S., Kadel, R. C., Sadaula, A., Dhakal, A., Faruque, M. O., et al. (2024) · Advanced Science · doi:10.1002/advs.202407615 · Cited by 8 · see citing works
Peylhard, M., Berthier, D., Dayo, G., Chantal, I., Sylla, S., Nidelet, S., Dubois, E., Martin, G., Sempéré, G., Flori, L., et al. (2023) · Peer Community Journal · doi:10.24072/pcjournal.239 · Cited by 8 · see citing works
Mapping restricted introgression across the genomes of admixed indigenous African cattle breeds
Friedrich, J., Bailey, R. I., Talenti, A., Chaudhry, U. N., Ali, Q., Obishakin, E., Ezeasor, C., Powell, J., Hanotte, O., Tijjani, A., et al. (2023) · Genetics Selection Evolution · doi:10.1186/s12711-023-00861-8 · Cited by 8 · see citing works
Self-citationVanvanhossou, S. F. U., Yin, T., Gorjanc, G., & König, S. (2025) · Genetics Selection Evolution · doi:10.1186/s12711-025-00952-8 · Cited by 8 · see citing works
Wang, X., Nursyifa, C., Aninta, S. G., Garcia‐Erill, G., Bertola, L. D., Khan, A., Kuja, J., Hanghøj, K., Meisner, J., Bøggild, T., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-62692-z · Cited by 9 · see citing works
Evidence of early genomic selection in Holstein Friesian across African and European ecosystems
Gao, J., González-Prendes, R., Liu, Y., Kantanen, J., Ginja, C., Ghanem, N., Kugonza, D. R., Makgahlela, M. L., Bovenhuis, H., Groenen, M. A. M., et al. (2025) · BMC Genomics · doi:10.1186/s12864-025-11828-y · Cited by 6 · see citing works
Okwasiimire, R., Kugonza, D. R., Gao, J., Weldenegodguad, M., Makgahlela, M. L., Ghanem, N., Ginja, C., Crooijmans, R. P. M. A., Kantanen, J., Uimari, P., et al. (2026) · Mammalian Genome · doi:10.1007/s00335-026-10193-9 · Cited by 6 · see citing works
Immune Response in Cattle Trypanosomosis and Trypanotolerance: Main Findings and Gaps
Somé, G. F., Séré, M., Somda, M. B., Dayo, G., Ouédraogo, G. A., Boulangé, A. F., Maarifi, G., Chantal, I., Berthier, D., & Thévenon, S. (2024) · Parasite Immunology · doi:10.1111/pim.13075 · Cited by 6 · see citing works
Admixture and selection offer insights for the conservation and breeding of Guyuan cattle
Liu, S., Yan, H., Feng, X., Luo, X., Lv, Y., Lei, C., Chen, N., & Ma, Y. (2025) · BMC Biology · doi:10.1186/s12915-025-02213-y · Cited by 6 · see citing works
dos Santos, C. A., Eler, J. P., Mattos, E. C., Espigolan, R., Giacomini, G., Ferraz, J. B. S., & Paim, T. D. P. (2024) · PLoS ONE · doi:10.1371/journal.pone.0301937 · Cited by 6 · see citing works
A novel SNP of TECPR2 gene associated with heat tolerance in Chinese cattle
Ma, X., Liu, Y., Sun, L., Hanif, Q., Qu, K., Liu, J., Zhang, J., Huang, B., & Lei, C. (2021) · Animal Biotechnology · doi:10.1080/10495398.2021.2011305 · Cited by 6 · see citing works
Genomic diversity of Cameroonian Gudali and Gudali-cross cattle
Matenchi, Y. P., & Hegarty, M. (2025) · Scientific Reports · doi:10.1038/s41598-025-99799-8 · Cited by 5 · see citing works
Riggio, V., Madder, M., Labuschagné, M., Callaby, R., Zhao, R., Djikeng, A., Fourie, J., Prendergast, J. G. D., & Morrison, L. J. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1197160 · Cited by 5 · see citing works
Multimodal interactions in Stomoxys navigation reveal synergy between olfaction and vision
Getahun, M. N., Baleba, S. B. S., Ngiela, J., Ahuya, P. O., & Masiga, D. K. (2024) · Scientific Reports · doi:10.1038/s41598-024-68726-8 · Cited by 5 · see citing works
Analysis of genomic copy number variations through whole-genome scan in Yunling cattle
Dang, D., Zhang, L., Gao, L., Peng, L., Chen, J., & Yang, L. (2024) · Frontiers in Veterinary Science · doi:10.3389/fvets.2024.1413504 · Cited by 4 · see citing works
Genome‐wide analysis of genetic diversity and selection signatures in Fuzhou cattle
Wang, N., Li, Y., Li, X., Li, H., Bian, C., Chen, X., Jafari, H., Chen, N., & Lei, C. (2025) · Animal Genetics · doi:10.1111/age.70015 · Cited by 4 · see citing works
Most Beefalo cattle have no detectable bison genetic ancestryPreprint
Shapiro, B., Oppenheimer, J., Heaton, M. P., Kuhn, K. L., Green, R. E., Blackburn, H. D., & Smith, T. P. L. (2024) · eLife · doi:10.7554/elife.102750.1 · Cited by 4 · see citing works
High quality genome assemblies of African cattle breeds using PacBio HiFi sequencing
Houaga, I., Bhati, M., Nziku, Z. C., Nguluma, A. S., Msuta, G., Ntanganedzeni, M., Nesengani, L. T., Ogugo, M., Sagbo, D. C. Y., Zorobouragui, L., et al. (2026) · Scientific Data · doi:10.1038/s41597-026-07589-2 · Cited by 4 · see citing works
The vision of big data recirculation for smart livestock farming in South Korea
Lee, S.-H., Lim, K., Lee, H., Heo, J.-Y., Kim, J., Kim, S.-H., Kim, S.-H., Park, J., Lim, D., Oh, J.-D., et al. (2025) · Journal of Animal Science and Technology · doi:10.5187/jast.2025.e21 · Cited by 3 · see citing works
Self-citationChernet, T. F., Tarekegn, G. M., Ally, O. M., Meseret, S., Mrode, R., Negussie, E., Edea, Z., Gebreyohanes, G., Ekine-Dzivenu, C. C., Tera, A., et al. (2025) · Animal Biotechnology · doi:10.1080/10495398.2025.2586262 · Cited by 3 · see citing works
Self-citationMcHugo, G. P., Ward, J. A., Ng’ang’a, S. I., Frantz, L., Salter‐Townshend, M., Hill, E. W., O’Gorman, G. M., Meade, K. G., Hall, T. J., & MacHugh, D. E. (2024) · Heredity · doi:10.1038/s41437-024-00734-w · Cited by 3 · see citing works
Local Ancestry and Adaptive Introgression in Xiangnan Cattle
Yan, H., Li, J., Zhang, K., Duan, H., Sun, A., Zhang, B., Li, F., Chen, N., Lei, C., & Yi, K. (2024) · Biology · doi:10.3390/biology13121000 · Cited by 3 · see citing works
GeMo: a web-based platform for the visualization and curation of genome ancestry mosaics
Summo, M., Comte, A., Martin, G., Perelle, P., Weitz, E. M., Droc, G., & Rouard, M. (2022) · Database · doi:10.1093/database/baac057 · Cited by 3 · see citing works
Basiladze, G., Tabatadze, L. V., Gabashvili, E., Osepashvili, M., Murtskhvaladze, M., & Kotetishvili, M. (2024) · Genetic Resources · doi:10.46265/genresj.hynz9140 · Cited by 2 · see citing works
Kambal, S., Walsh, A. T., Sivasankaran, S. K., Adossa, N. A., Skarlupka, J. H., Hanotte, O., Suen, G., & Elsik, C. G. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf1214 · Cited by 2 · see citing works
Self-citationKinkpe, L., Solomon, A. I., Niu, Y., Goswami, N., Ikele, C. M.-C., Di, H. U., Abdessan, R., Zhigang, H., & Xia, W. (2025) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-025-04755-3 · Cited by 2 · see citing works
Mavunga, T. K., Sölkner, J., Mészáros, G., Pichler, R., Zorobouragui, L., TRAORE, A., Tapsoba, A. S. R., Hamed, H., Hassan, Y. A., Chileshe, B., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-36562-7 · Cited by 2 · see citing works
Dai, S., Xu, L., Yang, L., Zhao, P., Li, X., Huang, W., Zhang, W., Dai, X., Li, Z., Peng, L., et al. (2026) · iMetaOmics. · doi:10.1002/imo2.70095 · Cited by 2 · see citing works
Koch, L. (2020) · Nature Reviews Genetics · doi:10.1038/s41576-020-00293-w · Cited by 2 · see citing works
Whole genome sequencing reveals signals of adaptive admixture in Creole cattlePreprint
Jemaa, S. B., Adam, G., Boussaha, M., Klopp, C., Mandonnet, N., & Navès, M. (2023) · doi:10.22541/au.167411887.77322425/v1 · Cited by 2 · see citing works
Meat animals, origin and domestication
Konarzewski, M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-85125-1.00139-3 · Cited by 2 · see citing works
The Genomic Landscape of Cattle: Domestication, Dispersal, and Adaptive Evolution
Liu, Y., Dao, W., Gao, R., Fan, X., Yang, R., & Miao, Y. (2026) · Animals · doi:10.3390/ani16050776 · Cited by 1 · see citing works
Tesfa, A., Alemayehu, K., Mebratie, W., Kerisew, B., & Taye, M. (2024) · Agricultural Reviews · doi:10.18805/ag.rf-281 · Cited by 1 · see citing works
Local Ancestry and Selection in the Genomes of Russian Black Pied Cattle
Igoshin, A. V., Yurchenko, A. A., Yudin, N. S., & Larkin, D. M. (2025) · Sci · doi:10.3390/sci7020051 · Cited by 1 · see citing works
Shi, L., Zhang, P., Yu, B., Cheng, L., Liu, S., Liu, Q., Zhou, Y., Xiang, M., Zhao, P., & Chen, H. (2025) · Animals · doi:10.3390/ani15121755 · Cited by 1 · see citing works
The History, Geography, and Characteristics of Indigenous African Taurine Cattle
Rege, J. E. O., Tawah, C. L., Houaga, I., & Ibeagha-Awemu, E. M. (2025) · Sustainable development goals series · doi:10.1007/978-3-031-92076-9_3 · Cited by 1 · see citing works
Ge, F., Guo, Y., Xu, L., Low, W. Y., Ma, H., Li, Q., Wang, Z., Zhu, B., Xu, L., Gao, X., et al. (2025) · DNA Research · doi:10.1093/dnares/dsaf034 · Cited by 1 · see citing works
Somé, G. F., Séré, M., Chantal, I., Somda, M. B., Dayo, G., Ouaré, M., Sakandé, H., Sempéré, G., Thévenon, S., & Berthier, D. (2025) · BMC Veterinary Research · doi:10.1186/s12917-025-05235-4 · Cited by 1 · see citing works
Alberts, D., van Marle-Köster, E., Joubert, F., & Berry, D. P. (2026) · Frontiers in Genetics · doi:10.3389/fgene.2026.1717538 · Cited by 1 · see citing works
Unscrambling the history of African indicine cattle genomes
Kassa, M., Woldekiros, H. S., Persichilli, C., Civita, M. D., Jemaa, S. B., Mastrangelo, S., Mwacharo, J. M., Hanotte, O., Pilla, F., & Senczuk, G. (2026) · iScience · doi:10.1016/j.isci.2026.115295 · Cited by 1 · see citing works
Self-citationGao, J., Ginja, C., Liu, Y., Kantanen, J., Ghanem, N., Kugonza, D. R., Makgahlela, M. L., Okwasiimire, R., Bovenhuis, H., Groenen, M. A. M., et al. (2026) · Communications Biology · doi:10.1038/s42003-026-09856-9 · Cited by 1 · see citing works
African Dairy Animals’ Genetic Diversity
Pastrana, C. I., Gaouar, S. B. S., Adoligbe, C. M., & Zibi, M. A. M. (2026) · Springer eBooks · doi:10.1007/978-3-032-15624-2_7 · Cited by 1 · see citing works
Runs of homozygosity reveal population dynamics and selection across global cattle
Ma, J., Liu, X., Gao, X., Wei, D., Zhang, Z., Muhammad, A., Chen, N., Xia, X., Ma, Y., Wang, E., et al. (2026) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-026-01403-0 · Cited by 1 · see citing works
Candidate genes and genomic regions relevant for adaptation to extreme climates in livestock
Cheruiyot, E. K., Negussie, E., Tarekegn, G. M., & Haile‐Mariam, M. (2025) · CABI Reviews · doi:10.1079/cabireviews.2025.0052 · Cited by 1 · see citing works
Self-citationThe distribution of a missense mutation in SDK1 gene across native Chinese breeds
Wan, P., Yang, X., Li, Y., Huang, B., & Cai, C. (2021) · Animal Biotechnology · doi:10.1080/10495398.2021.1974467 · Cited by 1 · see citing works
- Authors
- Kim, K., Kwon, T., Dessie, T., Yoo, D., Mwai, O. A., Jang, J., Sung, S., Lee, S., Salim, B., Jung, J., Jeong, H., Tarekegn, G. M., Tijjani, A., Lim, D., Cho, S., Oh, S. J., Lee, H.-K., Kim, J., Jeong, C., Kemp, S., Hanotte, O., & Kim, H.
- Affiliations
- Seoul National University (KR)
- International Livestock Research Institute (KE)
- University of Khartoum (SD)
- Swedish University of Agricultural Sciences (SE)
- Roslin Institute (GB)
- National Institute of Animal Science (KR)
- Jeonbuk National University (KR)
- Gyeongsang National University (KR)
- Corresponding author
- Hanotte, Olivier
- Kim, Heebal
- ORCID
- Venue
- Nature Genetics
- Published
- 2020-09-28
- Volume
- 52
- Issue
- 10
- Pages
- 1099-1110
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W3091710808
- Cited by
- 140
- References
- 135
- Citations by year
- 2026: 22 · 2025: 28 · 2024: 31 · 2023: 17 · 2022: 20 · 2021: 20 · 2020: 2
- FWCI
- 8.79
- Type
- journal article
- Language
- en
- Open access
- Locations
- Nature Genetics (publishedVersion)
- PubMed (publishedVersion)
- Repository@Nottingham (University of Nottingham) (submittedVersion, cc-by)
- CGSPace A Repository of Agricultural Research Outputs (Consultative Group for International Agricultural Research) (submittedVersion)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, other-oa)
- Seoul National University Open Repository (Seoul National University) (submittedVersion)
- Greater South Information System
- Funders
- Bill and Melinda Gates Foundation
- UK aid from the UK Government’s Department for International Development
- Rural Development Administration (PJ01323701, PJ01040601)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and phenotypic traits in livestock
- Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Livestock Farming and Management
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
- Keywords
- crossbreeding, genetic ancestry, environmental adaptation, trypanotolerance, trypanosomiasis, heat tolerance, immune-related genes, Horn of Africa, cattle breeds, genetic resources
- MeSH terms
- Whole Genome Sequencing, Adaptation, Physiological, Africa, Alleles, Animals, Breeding, Cattle, Genotype, Hot Temperature, Mosaicism, Reproduction, Genome, Polymorphism, Single Nucleotide
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review