Breakdown of the brain’s functional network modularity with awareness
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Significance: How the brain begets conscious awareness has been one of the most fundamental and elusive problems in neuroscience, psychology, and philosophy. Correspondingly, this problem has spawned a remarkably large number of theories that differ by the proposed extent of cortical and subcortical changes associated with awareness, ranging from local to global changes in functional connectivity. Graph theoretical techniques, in combination with functional magnetic resonance imaging, provide a well-suited tool to adjudicate between these disparate theories by characterizing whole-brain patterns of communication. In this paper, we demonstrate large-scale differences in functional connections with awareness of a visual target, consistent with global models of awareness.
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The timescales on which decoherence occurs in the environment of the brain are considerably shorter than neural firing rates.
“As initially calculated by Max Tegmark in response to Orch OR theory, the timescales on which decoherence occurs in the environment of the brain are considerably shorter than neural firing rates 47 .”
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- Authors
- Godwin, D., Barry, R. L., & Marois, R.
- Affiliations
- Department of Psychology,
- Vanderbilt University (US)
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2015-03-10
- Volume
- 112
- Issue
- 12
- Pages
- 3799-3804
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC4378398
- OpenAlex
- W2050365551
- Cited by
- 145
- References
- 77
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 6 · 2023: 6 · 2022: 8 · 2021: 11 · 2020: 17 · 2019: 14 · 2018: 22 · 2017: 28 · 2016: 17 · 2015: 5
- FWCI
- 14.44
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- HHS | National Institutes of Health (P30-EY008126, 5R01EB000461)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Keywords
- awareness, conscious perception, ultra-high field fMRI
- MeSH terms
- Adolescent, Adult, Algorithms, Awareness, Behavior, Brain Mapping, Consciousness, Female, Humans, Magnetic Resonance Imaging, Male, Models, Neurological, Nerve Net, Models, Statistical, Young Adult
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