Frequency-specific directed interactions in the human brain network for language
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Abstract
Significance: The brain’s remarkable capacity for language requires bidirectional interactions between functionally specialized brain regions. Although the functional role of individual regions in the brain network for language has been well studied, as of yet little is known about the mechanisms that facilitate the information exchange between these brain regions. In this paper we show that communication between language-relevant areas in the brain is supported by rhythmic neuronal synchronization and that different rhythms reflect the direction of information flow. These findings likely reflect a generic mechanism that allows for dynamic routing of information in a network of task-relevant brain regions during cognitive processing.
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Efferent information from temporal or parietal areas peaked around 12 Hz (beta frequency range), whereas directed influences from frontal to temporal areas were most prominent at a higher frequency (~27 Hz).
“They observed efferent information from temporal or parietal areas to peak around 12 Hz (beta frequency range), whereas directed influences from frontal to temporal areas was most prominent at a higher frequency ( ∼ 27 Hz).”
From Grounding the neurobiology of language in first principles: The necessity of non-language-centric explanations for language comprehension (2018) · cites this paper as Schoffelen et al., 2017
Schoffelen et al. (2017) showed that it is possible to determine the direction of information flow across brain regions during language comprehension.
“Schoffelen et al. (2017) extended this approach by showing that it is possible to determine the direction of information flow across brain regions during language comprehension.”
From Grounding the neurobiology of language in first principles: The necessity of non-language-centric explanations for language comprehension (2018) · cites this paper as Schoffelen et al. (2017)
Left inferior frontal and left anterior temporal cortices mainly received input from other areas, whereas middle temporal cortex mainly sent out information to other regions.
“It was found that left inferior frontal and left anterior temporal cortices mainly received input from other areas, whereas middle temporal cortex mainly sent out information to other regions.”
From Grounding the neurobiology of language in first principles: The necessity of non-language-centric explanations for language comprehension (2018) · cites this paper as Schoffelen et al., 2017
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Self-citation
- Authors
- Schoffelen, J.-M., Hultén, A., Lam, N., Marquand, A. F., Uddén, J., & Hagoort, P.
- Affiliations
- Radboud University Nijmegen (NL)
- Radboud University Nijmegen, Donders Institute for Brain, Cognition, and Behaviour, 6500 HB Nijmegen, The Netherlands;
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2017-07-11
- Volume
- 114
- Issue
- 30
- Pages
- 8083-8088
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC5544297
- OpenAlex
- W2594431083
- Cited by
- 128
- References
- 45
- Citations by year
- 2026: 11 · 2025: 12 · 2024: 8 · 2023: 17 · 2022: 12 · 2021: 15 · 2020: 18 · 2019: 18 · 2018: 15 · 2017: 2
- FWCI
- 8.32
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion)
- Max Planck Digital Library (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion, other-oa)
- Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek (864.14.011, SPI 80-114, 024.001.006)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- language network, interregional connectivity, Granger causality, functional connectivity, neural oscillations, alpha oscillations, beta oscillations, inferior frontal cortex, anterior temporal lobe, middle temporal cortex, reading, sentence processing, functional network topology, subnetworks, information flow
- MeSH terms
- Adolescent, Adult, Brain, Female, Humans, Language, Male, Speech, Magnetoencephalography, Young Adult
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