Influence of young adult cognitive ability and additional education on later-life cognition
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How and when education improves cognitive capacity is an issue of profound societal importance. Education and later-life education-related factors, such as occupational complexity and engagement in cognitive-intellectual activities, are frequently considered indices of cognitive reserve, but whether their effects are truly causal remains unclear. In this study, after accounting for general cognitive ability (GCA) at an average age of 20 y, additional education, occupational complexity, or engagement in cognitive-intellectual activities accounted for little variance in late midlife cognitive functioning in men age 56–66 ( n = 1009). Age 20 GCA accounted for 40% of variance in the same measure in late midlife and approximately 10% of variance in each of seven cognitive domains. The other factors each accounted for <1% of the variance in cognitive outcomes. The impact of these other factors likely reflects reverse causation—namely, downstream effects of early adult GCA. Supporting that idea, age 20 GCA, but not education, was associated with late midlife cortical surface area ( n = 367). In our view, the most parsimonious explanation of our results, a meta-analysis of the impact of education, and epidemiologic studies of the Flynn effect is that intellectual capacity gains due to education plateau in late adolescence/early adulthood. Longitudinal studies with multiple cognitive assessments before completion of education would be needed to confirm this speculation. If cognitive gains reach an asymptote by early adulthood, then strengthening cognitive reserve and reducing later-life cognitive decline and dementia risk may really begin with improving educational quality and access in childhood and adolescence.
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New work suggests overall cognitive ability increases with education before reaching a plateau in late adolescence, when the brain reaches greatest plasticity, with relatively few further gains from education after age 20 years.
“New work suggests overall cognitive ability increases, with education, before reaching a plateau in late adolescence, when brain reaches greatest plasticity; with relatively few further gains with education after age 20 years.38”
From Dementia prevention, intervention, and care: 2020 report of the Lancet Commission (2020) · cites this paper as [38]
The Abstract suggests that education-related gains in cognitive ability plateau in late adolescence or early adulthood, and the Discussion reports little additional effect of education after age 20. The Discussion describes substantial brain development during childhood and adolescence, but does not say that brain plasticity is greatest in late adolescence. (LLM, conf=0.86)
Experimental — accuracy not yet measuredIt is difficult to separate the specific impact of education from overall cognitive ability, and the specific impact of later-life cognitive activity from lifelong cognitive function and activity.
“It is difficult to separate out the specific impact of education from the effect of overall cognitive ability,38, 39 and the specific impact of later-life cognitive activity from lifelong cognitive function and activity.39, 40”
From Dementia prevention, intervention, and care: 2020 report of the Lancet Commission (2020) · cites this paper as [38]
This suggests cognitive stimulation is more important in early life, and much of the apparent later effect might be due to people of higher cognitive function seeking out cognitively stimulating activities and education.
“This suggests cognitive stimulation is more important in early life; much of the apparent later effect might be due to people of higher cognitive function seeking out cognitively stimulating activities and education.38”
From Dementia prevention, intervention, and care: 2020 report of the Lancet Commission (2020) · cites this paper as [38]
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Cites
Validation of a combined comorbidity index
Charlson, M., Szatrowski, T. P., Peterson, J., & Gold, J. (1994) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(94)90129-5 · Cited by 6,587 · see citing works
Social class and mental illness: Community study.
Hollingshead, A. B., & Redlich, F. C. (1958) · John Wiley & Sons, Inc. eBooks · doi:10.1037/10645-000 · Cited by 3,744 · see citing works
Cognitive reserve in ageing and Alzheimer's disease
Stern, Y. (2012) · The Lancet Neurology · doi:10.1016/s1474-4422(12)70191-6 · Cited by 3,557 · cited 1× · see citing works
“They are also frequently used as indices of cognitive reserve (7); for example, higher education is associated with greater resistance to Alzheimer’s disease (AD) pathology (4, 8).”
BackgroundSocial Class and Mental Illness: A Community Study
Hollingshead, A. B., & Redlich, F. C. (2007) · American Journal of Public Health · doi:10.2105/ajph.97.10.1756 · Cited by 1,845 · see citing works
Genotype-environment interaction and correlation in the analysis of human behavior.
Plomin, R., DeFries, J. C., & Loehlin, J. C. (1977) · Psychological Bulletin · doi:10.1037/0033-2909.84.2.309 · Cited by 1,685 · see citing works
Long-term Effects of Cognitive Training on Everyday Functional Outcomes in Older Adults
Willis, S. L., Tennstedt, S. L., Marsiske, M., Ball, K., Elias, J., Koepke, K. M., Morris, J. N., Rebok, G. W., Unverzagt, F. W., Stoddard, A. M., et al. (2006) · JAMA · doi:10.1001/jama.296.23.2805 · Cited by 1,496 · see citing works
Hertzog, C., Kramer, A. F., Wilson, R. S., & Lindenberger, U. (2008) · Psychological Science in the Public Interest · doi:10.1111/j.1539-6053.2009.01034.x · Cited by 1,495 · see citing works
Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
Li, J., & Ji, L. (2005) · Heredity · doi:10.1038/sj.hdy.6800717 · Cited by 1,458 · see citing works
Association of Child Poverty, Brain Development, and Academic Achievement
Hair, N. L., Hanson, J. L., Wolfe, B. L., & Pollak, S. D. (2015) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2015.1475 · Cited by 1,016 · see citing works
Efficiency, capacity, compensation, maintenance, plasticity: emerging concepts in cognitive reserve
Barulli, D., & Stern, Y. (2013) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2013.08.012 · Cited by 924 · see citing works
How Much Does Education Improve Intelligence? A Meta-Analysis
Ritchie, S. J., & Tucker-Drob, E. M. (2018) · Psychological Science · doi:10.1177/0956797618774253 · Cited by 680 · see citing works
The heritability of general cognitive ability increases linearly from childhood to young adulthood
Haworth, C., Wright, M., Luciano, M., Martin, N., de Geus, E. D., van Beijsterveldt, C. V., Bartels, M., Posthuma, D., Boomsma, D., Davis, O., et al. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.55 · Cited by 641 · see citing works
Johnson, S. B., Blum, R. W., & Giedd, J. N. (2009) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2009.05.016 · Cited by 631 · see citing works
Causal Inference and Observational Research: The Utility of Twins
McGue, M., Osler, M., & Christensen, K. (2010) · Perspectives on Psychological Science · doi:10.1177/1745691610383511 · Cited by 529 · see citing works
Regression models for twin studies: a critical review
Carlin, J. B., Gurrin, L. C., Sterne, J. A. C., Morley, R., & Dwyer, T. (2005) · International Journal of Epidemiology · doi:10.1093/ije/dyi153 · Cited by 472 · see citing works
Developmental Influences on Adult Intelligence: The Seattle Longitudinal Study
Schaie, K. W. (2012) · Medical Entomology and Zoology · Cited by 449 · see citing works
The Impact of Sustained Engagement on Cognitive Function in Older Adults: The Synapse Project
Park, D. C., Lodi-Smith, J., Drew, L., Haber, S., Hebrank, A., Bischof, G. N., & Aamodt, W. (2014) · Psychological Science · doi:10.1177/0956797613499592 · Cited by 404 · see citing works
Zahodne, L. B., Stern, Y., & Manly, J. J. (2014) · Neuropsychology · doi:10.1037/neu0000141 · Cited by 267 · see citing works
What provides cerebral reserve?
Staff, R. T., Murray, A. D., Deary, I. J., & Whalley, L. J. (2004) · Brain · doi:10.1093/brain/awh144 · Cited by 267 · see citing works
Developmental Influences on Adult Intelligence
Schaie, K. W. (2005) · doi:10.1093/acprof:oso/9780195156737.001.0001 · Cited by 253 · see citing works
Kremen, W. S., Prom‐Wormley, E. C., Panizzon, M. S., Eyler, L. T., Fischl, B. R., Neale, M. C., Franz, C. E., Lyons, M. J., Pacheco, J. L., Perry, M. E., et al. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.09.043 · Cited by 235 · see citing works
Self-citationSchooling in adolescence raises IQ scores
Brinch, C. N., & Galloway, T. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106077109 · Cited by 231 · see citing works
The Vietnam Era Twin (VET) Registry: Method of Construction
Eisen, S. A., True, W., Goldberg, J. H., Henderson, W. G., & Robinette, C. D. (1987) · Acta geneticae medicae et gemellologiae · doi:10.1017/s0001566000004591 · Cited by 231 · see citing works
Sundet, J. M., Barlaug, D., & Torjussen, T. M. (2004) · Intelligence · doi:10.1016/s0160-2896(04)00052-2 · Cited by 228 · see citing works
Flynn effect and its reversal are both environmentally caused
Bratsberg, B., & Rogeberg, O. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1718793115 · Cited by 199 · see citing works
Impact of the Baltimore Experience Corps Trial on cortical and hippocampal volumes
Carlson, M. C., Kuo, J. H., Chuang, Y., Varma, V. R., Harris, G., Albert, M. S., Erickson, K. I., Kramer, A. F., Parisi, J. M., Xue, Q., et al. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.12.005 · Cited by 197 · see citing works
Neurodevelopmental origins of lifespan changes in brain and cognition
Walhovd, K. B., Krogsrud, S. K., Amlien, I. K., Bartsch, H., Bjørnerud, A., Due‐Tønnessen, P., Grydeland, H., Hagler, D. J., Haberg, A. K., Kremen, W. S., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1524259113 · Cited by 196 · see citing works
Self-citationHealth Characteristics of Adults Aged 55 Years and Over: United States, 2004-2007
Schoenborn, C. A., & Heyman, K. M. (2009) · PsycEXTRA Dataset · doi:10.1037/e623972009-001 · Cited by 194 · see citing works
Wang, H.-X., MacDonald, S., Dekhtyar, S., & Fratiglioni, L. (2017) · PLoS Medicine · doi:10.1371/journal.pmed.1002251 · Cited by 170 · see citing works
A Life-Course Study of Cognitive Reserve in Dementia—From Childhood to Old Age
Dekhtyar, S., Wang, H., Scott, K., Goodman, A., Koupil, I., & Herlitz, A. (2015) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2015.02.002 · Cited by 155 · see citing works
Genes, Environment, and Time: The Vietnam Era Twin Study of Aging (VETSA)
Kremen, W. S., Thompson‐Brenner, H., Leung, Y.-M. J., Grant, M. D., Franz, C. E., Eisen, S. A., Jacobson, K. C., Boake, C., & Lyons, M. J. (2006) · Twin Research and Human Genetics · doi:10.1375/183242706779462750 · Cited by 147 · see citing works
Self-citationBoots, E. A., Schultz, S. A., Almeida, R. P., Oh, J. M., Koscik, R. L., Dowling, N. M., Gallagher, C. L., Carlsson, C. M., Rowley, H. A., Bendlin, B. B., et al. (2015) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/acv041 · Cited by 139 · see citing works
Genes, Environment, and Time: The Vietnam Era Twin Study of Aging (VETSA)
Kremen, W. S., Thompson‐Brenner, H., Leung, Y.-M. J., et al. (2006) · Twin Research and Human Genetics · doi:10.1375/twin.9.6.1009 · Cited by 130 · see citing works
Self-citationLyons, M. J., York, T. P., Franz, C. E., Grant, M. D., Eaves, L. J., Jacobson, K. C., Schaie, K. W., Panizzon, M. S., Boake, C., Xian, H., et al. (2009) · Psychological Science · doi:10.1111/j.1467-9280.2009.02425.x · Cited by 125 · see citing works
Self-citationLee, A. T. C., Richards, M., Chan, W. C., Chiu, H. F. K., Lee, R. S. Y., & Lam, L. C. W. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.0657 · Cited by 124 · see citing works
VETSA: The Vietnam Era Twin Study of Aging
Kremen, W. S., Franz, C. E., & Lyons, M. J. (2012) · Twin Research and Human Genetics · doi:10.1017/thg.2012.86 · Cited by 113 · see citing works
Self-citationEyler, L., Prom-Wormley, E., Panizzon, M., Kaup, A., Fennema-Notestine, C., Neale, M. C., Jernigan, T., Fischl, B., Franz, C., Lyons, M. J., et al. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr013 · Cited by 113 · see citing works
Self-citationLogue, M. W., Panizzon, M. S., Elman, J. A., Gillespie, N. A., Hatton, S. N., Gustavson, D. E., Andreassen, O. A., Dale, A. M., Franz, C. E., Lyons, M. J., et al. (2018) · Molecular Psychiatry · doi:10.1038/s41380-018-0030-8 · Cited by 113 · see citing works
Self-citationClouston, S., Kuh, D. J., Herd, P., Elliott, J., Richards, M., & Hofer, S. M. (2012) · International Journal of Epidemiology · doi:10.1093/ije/dys148 · Cited by 111 · see citing works
Ritchie, S. J., Bates, T. C., Der, G., Starr, J. M., & Deary, I. J. (2012) · Psychology and Aging · doi:10.1037/a0030820 · Cited by 109 · see citing works
Vuoksimaa, E., Panizzon, M. S., Chen, C., Fiecas, M. J. A., Eyler, L. T., Fennema‐Notestine, C., Hagler, D. J., Fischl, B. R., Franz, C. E., Jak, A. J., et al. (2014) · Cerebral Cortex · doi:10.1093/cercor/bhu018 · Cited by 106 · see citing works
Self-citationInconsistency Between Univariate and Multiple Logistic Regressions.
Wang, H., Peng, J., Wang, B., Lu, X., Zheng, J. Z., Wang, K., Tu, X. M., & Feng, C. (2017) · PubMed Central · doi:10.11919/j.issn.1002-0829.217031 · Cited by 87 · see citing works
Self-citationReverse causation in activity-cognitive ability associations: The Lothian Birth Cohort 1936.
Gow, A. J., Corley, J., Starr, J. M., & Deary, I. J. (2011) · Psychology and Aging · doi:10.1037/a0024144 · Cited by 81 · see citing works
The Synapse Project: Engagement in mentally challenging activities enhances neural efficiency
McDonough, I. M., Haber, S., Bischof, G. N., & Park, D. C. (2015) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-150533 · Cited by 81 · see citing works
Dekhtyar, S., Wang, H., Fratiglioni, L., & Herlitz, A. (2016) · International Journal of Epidemiology · doi:10.1093/ije/dyw008 · Cited by 78 · see citing works
Early identification and heritability of mild cognitive impairment
Kremen, W. S., Jak, A. J., Panizzon, M. S., Spoon, K. M., Franz, C. E., Thompson, W. K., Jacobson, K. C., Vasilopoulos, T., Vuoksimaa, E., Xian, H., et al. (2013) · International Journal of Epidemiology · doi:10.1093/ije/dyt242 · Cited by 70 · see citing works
Self-citationHealthy cognitive ageing in the Lothian Birth Cohort studies: marginal gains not magic bullet
Corley, J., Cox, S. R., & Deary, I. J. (2017) · Psychological Medicine · doi:10.1017/s0033291717001489 · Cited by 68 · see citing works
Genetic and environmental influences on cortical mean diffusivity
Elman, J. A., Panizzon, M. S., Hagler, D. J., Fennema‐Notestine, C., Eyler, L. T., Gillespie, N. A., Neale, M. C., Lyons, M. J., Franz, C. E., McEvoy, L. K., et al. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.11.032 · Cited by 65 · see citing works
Self-citationFranz, C. E., Lyons, M. J., O'Brien, R., Panizzon, M. S., Kim, K., Bhat, R., Grant, M. D., Toomey, R., Eisen, S., Xian, H., et al. (2011) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3181ef79f1 · Cited by 62 · see citing works
Self-citationA longitudinal twin study of general cognitive ability over four decades.
Lyons, M. J., Panizzon, M. S., Liu, W., McKenzie, R. E., Bluestone, N., Grant, M. D., Franz, C. E., Vuoksimaa, E., Toomey, R., Jacobson, K. C., et al. (2017) · Developmental Psychology · doi:10.1037/dev0000303 · Cited by 61 · see citing works
Self-citationMotes, M. A., Yezhuvath, U. S., Aslan, S., Spence, J. S., Bart Rypma, A., & Chapman, S. B. (2017) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2017.10.003 · Cited by 61 · see citing works
Stine‐Morrow, E. A. L., & Basak, C. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-380882-0.00010-3 · Cited by 57 · see citing works
Lifestyle Risk and Delaying Factors
Gatz, M., Prescott, C. A., & Pedersen, N. L. (2006) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-200607001-00013 · Cited by 54 · see citing works
Genetic and environmental architecture of executive functions in midlife.
Gustavson, D. E., Panizzon, M. S., Franz, C. E., Friedman, N. P., Reynolds, C. A., Jacobson, K. C., Xian, H., Lyons, M. J., & Kremen, W. S. (2018) · Neuropsychology · doi:10.1037/neu0000389 · Cited by 53 · see citing works
Self-citationNegative fateful life events in midlife and advanced predicted brain aging
Hatton, S. N., Franz, C. E., Elman, J. A., Panizzon, M. S., Hagler, D. J., Fennema‐Notestine, C., Eyler, L. T., McEvoy, L. K., Lyons, M. J., Dale, A. M., et al. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.03.004 · Cited by 45 · see citing works
Self-citationOsler, M., Christensen, G. T., Garde, E., Mortensen, E. L., & Christensen, K. (2017) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2017.04.003 · Cited by 43 · see citing works
DEVELOPMENT OF ARMED FORCES QUALIFICATION TEST AND PREDECESSOR ARMY SCREENING TESTS, 1946-1950
Uhlaner, J. E., & Bolanovich, D. J. (1952) · doi:10.21236/ad0000191 · Cited by 38 · see citing works
Beck, A., Franz, C., Xian, H., Vuoksimaa, E., Tu, X., Reynolds, C., Panizzon, M., McKenzie, R., Lyons, M., Toomey, R., et al. (2018) · Innovation in aging · doi:10.1093/geroni/igy003 · Cited by 37 · see citing works
Self-citationPedersen, N. L., Reynolds, C. A., & Gatz, M. (1996) · The Journals of Gerontology Series B · doi:10.1093/geronb/51b.2.p55 · Cited by 27 · see citing works
Self-citationMiddle age self-report risk score predicts cognitive functioning and dementia in 20–40 years
Vuoksimaa, E., Rinne, J., Lindgren, N., Heikkilä, K., Koskenvuo, M., & Kaprio, J. (2016) · Alzheimer's & Dementia · doi:10.1016/j.dadm.2016.08.003 · Cited by 27 · see citing works
Self-citationGenetic mediation in the relationship of education to cognitive function in older people.
Carmelli, D., Swan, G. E., & Cardon, L. R. (1995) · Psychology and Aging · doi:10.1037//0882-7974.10.1.48 · Cited by 10 · see citing works
Genetic mediation in the relationship of education to cognitive function in older people.
Carmelli, D., Swan, G. E., & Cardon, L. R. (1995) · Psychology and Aging · doi:10.1037/0882-7974.10.1.48 · Cited by 7 · see citing works
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Livingston, G., Huntley, J., Sommerlad, A., Ames, D., Ballard, C., Banerjee, S., Brayne, C., Burns, A., Cohen-Mansfield, J., Cooper, C., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30367-6 · Cited by 10,430 · see citing works
“38 This suggests cognitive stimulation is more important in early life; much of the apparent later effect might be due to people of higher cognitive function seeking out cognitively stimulating activities and education.”
RetractedBrain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
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Dementia Prevention and Treatment
Reuben, D. B., Kremen, S. A., & Maust, D. T. (2024) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2023.8522 · Cited by 214 · see citing works
Timing of lifespan influences on brain and cognition
Walhovd, K. B., Lövden, M., & Fjell, A. M. (2023) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2023.07.001 · Cited by 112 · see citing works
Cognitive reserve and brain maintenance in aging and dementia: An integrative review
Pereira, G. Á., Nunes, M. V. S., Alzola, P., & Contador, I. (2021) · Applied Neuropsychology Adult · doi:10.1080/23279095.2021.1872079 · Cited by 80 · see citing works
Kremen, W. S., Elman, J. A., Panizzon, M. S., Eglit, G. M. L., Sanderson‐Cimino, M. E., Williams, M. E., Lyons, M. J., & Franz, C. E. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.834765 · Cited by 80 · see citing works
Self-citationLlorens-Gámez, M., Higuera-Trujillo, J. L., Omarrementería, C. S., & Llinares, C. (2021) · Frontiers of Architectural Research · doi:10.1016/j.foar.2021.12.002 · Cited by 55 · see citing works
Declines in grip strength may indicate early changes in cognition in healthy middle-aged adults
Adamo, D. E., Anderson, T., Koochaki, M., & Fritz, N. E. (2020) · PLoS ONE · doi:10.1371/journal.pone.0232021 · Cited by 52 · see citing works
Current Status of the Vietnam Era Twin Study of Aging (VETSA)
Kremen, W. S., Franz, C. E., & Lyons, M. J. (2019) · Twin Research and Human Genetics · doi:10.1017/thg.2019.125 · Cited by 51 · see citing works
Self-citationEpidemiology and Risk Factors for Dementia
Dintica, C. S., & Yaffe, K. S. (2022) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2022.07.011 · Cited by 49 · see citing works
Greenfield, E. A., Moorman, S. M., & Rieger, A. (2020) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbaa062 · Cited by 47 · see citing works
Beyond “Use It or Lose It”: The Impact of Engagement on Cognitive Aging
Stine‐Morrow, E. A. L., & Manavbasi, I. E. (2022) · Annual Review of Developmental Psychology · doi:10.1146/annurev-devpsych-121020-030017 · Cited by 46 · see citing works
Negative fateful life events in midlife and advanced predicted brain aging
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Self-citationGreater lifestyle engagement is associated with better age-adjusted cognitive abilities
Borgeest, G. S., Henson, R. N., Shafto, M. A., Samu, D., Cam-CAN, & Kievit, R. (2020) · PLoS ONE · doi:10.1371/journal.pone.0230077 · Cited by 44 · see citing works
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Tang, R., Panizzon, M. S., Elman, J. A., Gillespie, N. A., Hauger, R. L., Rissman, R. A., Lyons, M. J., Neale, M. C., Reynolds, C. A., Franz, C. E., et al. (2022) · Alzheimer s Research & Therapy · doi:10.1186/s13195-022-01134-0 · Cited by 40 · see citing works
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Hegelund, E. R., Grønkjær, M., Osler, M., Dammeyer, J., Flensborg-Madsen, T., & Mortensen, E. L. (2020) · Intelligence · doi:10.1016/j.intell.2019.101419 · Cited by 38 · see citing works
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Edwin, T. H., Haberg, A. K., Zotcheva, E., Bratsberg, B., Jugessur, A., Engdahl, B., Bowen, C. E., Selbæk, G., Kohler, H., Harris, J. R., et al. (2024) · Neurology · doi:10.1212/wnl.0000000000209353 · Cited by 34 · see citing works
Bransby, L., Rosenich, E., Maruff, P. T., & Lim, Y. Y. (2023) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2023.119 · Cited by 35 · see citing works
Balduino, E., de Melo, B. A. R., da Silva, L. D. S. M., Martinelli, J. E., & Cecato, J. F. (2019) · International Psychogeriatrics · doi:10.1017/s1041610219001364 · Cited by 34 · see citing works
Franz, C. E., Hatton, S. N., Elman, J. A., Warren, T. S., Gillespie, N. A., Whitsel, N. A., Puckett, O. K., Dale, A. M., Eyler, L. T., Fennema‐Notestine, C., et al. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.08.007 · Cited by 34 · see citing works
Self-citationBöttcher, A., Zarucha, A., Köbe, T., Gaubert, M., Höppner, A., Fabel, K. S., Altenstein, S., Bartels, C., Büerger, K., Dechent, P., et al. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.945709 · Cited by 36 · see citing works
Gustavson, D. E., Elman, J. A., Panizzon, M. S., Franz, C. E., Zuber, J., Sanderson‐Cimino, M. E., Reynolds, C. A., Jacobson, K. C., Xian, H., Jak, A. J., et al. (2020) · Neurology · doi:10.1212/wnl.0000000000010130 · Cited by 31 · see citing works
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Steffener, J. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.10.034 · Cited by 32 · see citing works
Backhouse, E. V., Boardman, J. P., & Wardlaw, J. M. (2023) · Hypertension · doi:10.1161/hypertensionaha.122.19940 · Cited by 31 · see citing works
The “Golden Age” of Behavior Genetics?
Charney, E. (2022) · Perspectives on Psychological Science · doi:10.1177/17456916211041602 · Cited by 29 · see citing works
Yang, Y., Chen, Y., Yang, C., Chen, K., Li, X., & Zhang, Z. (2022) · BMC Geriatrics · doi:10.1186/s12877-022-03530-5 · Cited by 27 · see citing works
Polygenic resilience scores capture protective genetic effects for Alzheimer’s disease
Hou, J., Hess, J., Armstrong, N. J., Bis, J. C., Grenier‐Boley, B., Karlsson, I., Leonenko, G., Numbers, K. T., O’Brien, E. K., Shadrin, A. A., et al. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02055-0 · Cited by 25 · see citing works
Self-citationCATSLife: A Study of Lifespan Behavioral Development and Cognitive Functioning
Wadsworth, S. J., Corley, R. P., Muñoz, E., Trubenstein, B. P., Knaap, E., DeFries, J. C., Plomin, R. J., Reynolds, C. A., & The CATSLife Team (2019) · Twin Research and Human Genetics · doi:10.1017/thg.2019.49 · Cited by 24 · see citing works
Self-citationCao, X. (2023) · Psychological Reports · doi:10.1177/00332941231175833 · Cited by 27 · see citing works
Early-life education may help bolster declarative memory in old age, especially for women
Reifegerste, J., Veríssimo, J., Rugg, M. D., Pullman, M. Y., Babcock, L., Glei, D. A., Weinstein, M., Goldman, N., & Ullman, M. T. (2020) · Aging Neuropsychology and Cognition · doi:10.1080/13825585.2020.1736497 · Cited by 24 · see citing works
Santamaría‐García, H. A., Moguilner, S., Rodríguez‐Villagra, O. A., Rodríguez, F. B., Piña‐Escudero, S. D., O’Donovan, G., Cecilia Albala, B., Matallana, D., Schulte, M., Slachevsky, A., et al. (2023) · GeroScience · doi:10.1007/s11357-023-00755-z · Cited by 23 · see citing works
Metabolic Profiling of Cognitive Aging in Midlife
Huo, Z., Rana, B. K., Elman, J. A., Dong, R., Engelman, C. D., Johnson, S. C., Lyons, M. J., Franz, C. E., Kremen, W. S., & Zhao, J. (2020) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2020.555850 · Cited by 20 · see citing works
Self-citationLeist, A. K., Bar-Haim, E., & Chauvel, L. (2021) · SSM - Population Health · doi:10.1016/j.ssmph.2021.100837 · Cited by 22 · see citing works
Iso‐Markku, P., Kaprio, J. A., Lindgrén, N., Rinne, J. O., & Vuoksimaa, E. (2021) · Age and Ageing · doi:10.1093/ageing/afab228 · Cited by 22 · see citing works
Self-citationKrasnova, A., Tom, S. E., Valeri, L., Crane, P. K., & Bennett, D. A. (2023) · American Journal of Epidemiology · doi:10.1093/aje/kwad033 · Cited by 22 · see citing works
Does early disaster exposure affect household agricultural income? Evidence from China
Cheng, Z., Zhu, Z., Zhang, H., & Liu, H. (2023) · International Journal of Disaster Risk Reduction · doi:10.1016/j.ijdrr.2023.103702 · Cited by 21 · see citing works
Occupational complexity and cognition in the FINGER multidomain intervention trial
Rydström, A., Darin‐Mattsson, A., Kåreholt, I., Ngandu, T., Lehtisalo, J., Solomon, A., Antikaínen, R., Bäckman, L., Hänninen, T., Laatikainen, T. K., et al. (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12561 · Cited by 20 · see citing works
A lifespan perspective on cognitive reserve and risk for dementia
Kremen, W. S., Ericsson, M., Gatz, M., Karlsson, I., Nygaard, M., Pedersen, N. L., & Panizzon, M. S. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70176 · Cited by 19 · see citing works
Self-citationCohort and Period Effects as Explanations for Declining Dementia Trends and Cognitive Aging
Clouston, S., Terrera, G. M., Rodgers, J. L., O’Keefe, P., Mann, F. D., Lewis, N. A., Wänström, L., Kaye, J. A., & Hofer, S. M. (2021) · Population and Development Review · doi:10.1111/padr.12409 · Cited by 19 · see citing works
Zaheed, A. B., Chervin, R. D., Spira, A. P., & Zahodne, L. B. (2022) · SLEEP · doi:10.1093/sleep/zsac262 · Cited by 22 · see citing works
Tang, R., Elman, J. A., Franz, C. E., Dale, A. M., Eyler, L. T., Fennema‐Notestine, C., Hagler, D. J., Lyons, M. J., Panizzon, M. S., Puckett, O. K., et al. (2022) · GeroScience · doi:10.1007/s11357-022-00676-3 · Cited by 16 · see citing works
Self-citationPharmacists’ Knowledge of Factors Associated with Dementia: The A-to-Z Dementia Knowledge List
Ramos, H., Moreno, L., Gil‐Peinado, M., García‐Lluch, G., Sendra‐Lillo, J., & Alacreu, M. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18199934 · Cited by 18 · see citing works
Reserve, resilience and maintenance of episodic memory and other cognitive functions in aging
Schwarz, C., Franz, C. E., Kremen, W. S., & Vuoksimaa, E. (2024) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2024.04.011 · Cited by 17 · see citing works
Self-citationLearning as an Important Privilege: A Life Span Perspective with Implications for Successful Aging
Wu, R., Zhao, J., Cheung, C. S.-S., Natsuaki, M. N., Rebok, G. W., & Strickland-Hughes, C. M. (2021) · Human Development · doi:10.1159/000514554 · Cited by 17 · see citing works
Huq, A. J., Fulton‐Howard, B., Riaz, M., Laws, S., Sebra, R., Ryan, J., Alzheimer's Disease Genetics Consortium, Renton, A. E., Goate, A. M., Masters, C. L., et al. (2021) · Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring · doi:10.1002/dad2.12226 · Cited by 17 · see citing works
Dobyns, L., Zhuang, K., Baker, S. L., Mungas, D., Jagust, W. J., & Harrison, T. M. (2023) · Nature Aging · doi:10.1038/s43587-022-00353-2 · Cited by 16 · see citing works
Huh, J., Arpawong, T. E., Gruenewald, T. L., Fisher, G. G., Prescott, C. A., Manly, J. J., Šeblová, D., Walters, E. E., & Gatz, M. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.13739 · Cited by 15 · see citing works
Metabolites Associated with Early Cognitive Changes Implicated in Alzheimer’s Disease
Darst, B. F., Huo, Z., Jonaitis, E. M., Koscik, R. L., Clark, L. R., Lu, Q., Kremen, W. S., Franz, C. E., Rana, B., Lyons, M. J., et al. (2021) · Journal of Alzheimer’s Disease · doi:10.3233/jad-200176 · Cited by 16 · see citing works
Self-citationModifiable risk factors of dementia linked to excitation-inhibition imbalance
Hafizi, S., & Rajji, T. K. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101804 · Cited by 15 · see citing works
Harrati, A., & Glymour, M. M. (2019) · Social Science & Medicine · doi:10.1016/j.socscimed.2019.112645 · Cited by 15 · see citing works
Brinza, I., Boiangiu, R. Ş., Mihăşan, M., Gorgan, L., Stache, A. B., Abd-Alkhalek, A. M., El‐Nashar, H. A. S., Ayoub, I. M., Mostafa, N. M., Eldahshan, O. A., et al. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.177013 · Cited by 16 · see citing works
Changes in neighborhood-level socioeconomic disadvantage and older Americans’ cognitive functioning
Settels, J., & Leist, A. K. (2021) · Health & Place · doi:10.1016/j.healthplace.2021.102510 · Cited by 14 · see citing works
Ford, K. J., Kobayashi, L. C., & Leist, A. K. (2022) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbac075 · Cited by 13 · see citing works
Temircan, Z. (2023) · Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry · doi:10.18863/pgy.1246718 · Cited by 14 · see citing works
Ophey, A., Wirtz, K., Wolfsgruber, S., Balzer‐Geldsetzer, M., Berg, D., Hilker-Roggendorf, R., Kassubek, J., Liepelt‐Scarfone, I., Becker, S., Mollenhauer, B., et al. (2024) · Journal of Neurology · doi:10.1007/s00415-024-12484-0 · Cited by 12 · see citing works
Occupational cognitive complexity and episodic memory in old age
Sörman, D. E., Stenling, A., Sundström, A., Rönnlund, M., Vega‐Mendoza, M., Hansson, P., & Ljungberg, J. K. (2021) · Intelligence · doi:10.1016/j.intell.2021.101598 · Cited by 12 · see citing works
Dinse, H. R. (2020) · Springer eBooks · doi:10.1007/978-3-030-47645-8_7 · Cited by 12 · see citing works
Chalhoub, T., Mackenzie, E., & Siette, J. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1401806 · Cited by 11 · see citing works
Sanderson‐Cimino, M. E., Panizzon, M. S., Elman, J. A., Tu, X. M., Gustavson, D. E., Puckett, O. K., Cross, K., Notestine, R. J., Hatton, S. N., Eyler, L. T., et al. (2021) · Neuropsychology · doi:10.1037/neu0000718 · Cited by 11 · see citing works
Self-citationGu, H., Yao, X., Diao, C., Liu, M., Kong, W., Liu, H., Zhao, Y., & Meng, Z. (2022) · BMC Geriatrics · doi:10.1186/s12877-022-03603-5 · Cited by 11 · see citing works
Nyberg, L. H., Grande, X., Andersson, M., Berron, D., Lundquist, A., Stiernstedt, M., Fjell, A. M., Walhovd, K. B., & Orädd, G. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.06.005 · Cited by 11 · see citing works
Shared Neural Substrates Underlying Reading and Visual Matching: A Longitudinal Investigation
Cui, X., Xia, Z., McBride, C. A., Li, P., Pan, J., & Hua Shu, A. (2020) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2020.567541 · Cited by 11 · see citing works
Cognitive ability in old age is predetermined by age 20 y
Park, D. C. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1821142116 · Cited by 11 · see citing works
The impact of Alzheimer’s disease risk factors on the pupillary light response
Sparks, S., Pinto, J., Hayes, G., Spitschan, M., & Bulte, D. P. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1248640 · Cited by 9 · see citing works
Lei, C., Wu, G., Cui, Y., Xia, H., Chen, J., Zhan, X., Lv, Y., Li, M., Zhang, R., & Zhu, X. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1290286 · Cited by 10 · see citing works
Tang, R., Buchholz, E. J., Dale, A. M., Rissman, R. A., Fennema‐Notestine, C., Gillespie, N. A., Hagler, D. J., Lyons, M. J., Neale, M. C., Panizzon, M. S., et al. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01464-1 · Cited by 11 · see citing works
Self-citationLi, Y., Tang, A.-J., Ge, L., Zhang, L., Chen, L., Xu, Y., Wang, L., Zhu, X., & Wu, Q. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1403027 · Cited by 10 · see citing works
Gustavson, D., Borriello, G. A., Karhadkar, M. A., Rhee, S., Corley, R. P., Rhea, S., DiLalla, L. F., Wadsworth, S. J., Friedman, N. P., & Reynolds, C. A. (2025) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2426531122 · Cited by 11 · see citing works
Self-citationFord, K. J., & Leist, A. K. (2021) · Gerontology and Geriatric Medicine · doi:10.1177/23337214211004366 · Cited by 10 · see citing works
Feinkohl, I., Kozma, P., Borchers, F., van Montfort, S. J. T., Kruppa, J., Winterer, G., Spies, C., & Pischon, T. (2021) · BMC Geriatrics · doi:10.1186/s12877-021-02290-y · Cited by 9 · see citing works
Khare, C., Mueser, K. T., & McGurk, S. R. (2022) · Schizophrenia Research Cognition · doi:10.1016/j.scog.2022.100255 · Cited by 10 · see citing works
The effect of online social evaluation on mood and cognition in young people
Grunewald, K., Deng, J., Wertz, J., & Schweizer, S. (2022) · Scientific Reports · doi:10.1038/s41598-022-24932-w · Cited by 9 · see citing works
Wang, G., Cheng, Z., Zhou, Y., Duan, J., Kan, Q., & Tang, S. (2023) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2023.105060 · Cited by 8 · see citing works
Wolfram, T., Ruks, M., & Spinath, F. M. (2024) · Research in Social Stratification and Mobility · doi:10.1016/j.rssm.2024.100980 · Cited by 8 · see citing works
Migeot, J., Araya-Ríos, D., Montecinos, M., Báez, S., Behrens, M. I., Castañer, O., Cruzat, J., Delgado, C., Jong-Bambagioni, D. D., Duran-Aniotz, C. A., et al. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.10.043 · Cited by 8 · see citing works
Iso‐Markku, P., Kaprio, J. A., Lindgrén, N., Rinne, J. O., & Vuoksimaa, E. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2020-324009 · Cited by 8 · see citing works
Self-citationGreater lifestyle engagement is associated with better cognitive resiliencePreprint
Borgeest, G. S., Henson, R. N., Shafto, M. A., Samu, D., Cam‐CAN, & Kievit, R. (2018) · doi:10.31234/osf.io/6pzve · Cited by 8 · see citing works
Aldaz, K. J., Flores, S. O., Ortiz, R. M., Rios, L. K. D., & Dhillon, J. (2022) · Nutrients · doi:10.3390/nu14245215 · Cited by 9 · see citing works
Zhu, L., Ming, Y., Wu, M., Zhang, X., Wang, X., Li, H., Lin, Z., Gao, F., & Zhu, Y. (2023) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202300673 · Cited by 7 · see citing works
Jin, J., Sommerlad, A., & Mukadam, N. (2024) · GeroScience · doi:10.1007/s11357-024-01285-y · Cited by 7 · see citing works
Factual models for human capital assessment
Shcherbakov, A. (2023) · Journal of New Economy · doi:10.29141/2658-5081-2023-24-2-5 · Cited by 7 · see citing works
Walters, E. E., Luczak, S. E., Beam, C. R., Ericsson, M., Kremen, W. S., Krueger, R. F., Markon, K. E., McGue, M. K., Nygaard, M., Panizzon, M. S., et al. (2025) · European Journal of Epidemiology · doi:10.1007/s10654-025-01286-x · Cited by 6 · see citing works
Self-citationKatayama, O., Lee, S., Bae, S., Makino, K., Chiba, I., Harada, K., Morikawa, M., Tomida, K., & Shimada, H. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11247441 · Cited by 6 · see citing works
Genetic and Environmental Influences on Semantic Verbal Fluency Across Midlife and Later Life
Gustavson, D., Panizzon, M., Kremen, W., Reynolds, C., Pahlen, S., Nygaard, M., Wod, M., Catts, V., Lee, T. M., Gatz, M., et al. (2020) · Behavior Genetics · doi:10.1007/s10519-021-10048-w · Cited by 6 · see citing works
Self-citationPOPOVICI, L.-F., Brinza, I., Oancea, S., & Hriţcu, L. (2025) · Pharmaceuticals · doi:10.3390/ph18101483 · Cited by 5 · see citing works
Waggestad, T. H., Kirsebom, B., Strobel, C., Gjøra, L., Selbæk, G., Bekkhus‐Wetterberg, P., Aga, O. O., & Egeland, J. (2025) · The Clinical Neuropsychologist · doi:10.1080/13854046.2025.2469940 · Cited by 5 · see citing works
Pereira, G. Á., Maruta, C., & Nunes, M. V. S. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.104646 · Cited by 6 · see citing works
Immunosenescence and Alzheimer’s Disease
Fülöp, T., Larbi, A., Khalil, A., Plotka, A., Laurent, B., Ramassamy, C., Bosco, N., Hirokawa, K., Frost, E. H., & Witkowski, J. M. (2021) · Healthy ageing and longevity · doi:10.1007/978-3-030-87532-9_9 · Cited by 5 · see citing works
Montague, L. A., Hespos, S. J., Mackenzie, E., & Siette, J. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1383270 · Cited by 4 · see citing works
Paradoxical cognitive trajectories in men from earlier to later adulthood
Eglit, G. M. L., Elman, J. A., Panizzon, M. S., Sanderson‐Cimino, M. E., Williams, M. E., Dale, A. M., Eyler, L. T., Fennema‐Notestine, C., Gillespie, N. A., Gustavson, D. E., et al. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.10.002 · Cited by 4 · see citing works
Self-citationLima, C. A. D. M., Ayalon, L., Banerjee, D., Peisah, C., & Rabheru, K. (2023) · International Psychogeriatrics · doi:10.1017/s104161022300056x · Cited by 4 · see citing works
Zheng, A., Friedman, N. P., Gustavson, D., Corley, R. P., Wadsworth, S. J., & Reynolds, C. A. (2024) · Alzheimer's & Dementia · doi:10.1002/dad2.12609 · Cited by 4 · see citing works
Self-citationCollege Selectivity and Later-Life Memory Function: Evidence From the Wisconsin Longitudinal Study
García, S., & Moorman, S. M. (2020) · Research on Aging · doi:10.1177/0164027520927137 · Cited by 4 · see citing works
Jagust, W. J. (2021) · Nature Aging · doi:10.1038/s43587-021-00048-0 · Cited by 4 · see citing works
Clustering on longitudinal lifestyle trajectories and their impact on cognitive performance
Roca‐Ventura, A., Sánchez, J. S., Cattaneo, G., Alviarez‐Schulze, V., España‐Irla, G., Redondo‐Camós, M., Delgado‐Gallén, S., Romero, R., Buloz-Osorio, E., Pascual‐Leone, Á., et al. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1510971 · Cited by 3 · see citing works
Eriksson, K., Sorjonen, K., Falkstedt, D., Melin, B., & Nilsonne, G. (2024) · Royal Society Open Science · doi:10.1098/rsos.230513 · Cited by 3 · see citing works
de Coca, T. L., Moreno, L., Pardo, J., Pérez‐Tur, J., Ramos, H., & Villagrasa, V. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1395877 · Cited by 3 · see citing works
Sergio, J. P., & Siedlecki, K. L. (2022) · Aging Neuropsychology and Cognition · doi:10.1080/13825585.2022.2131714 · Cited by 3 · see citing works
- Authors
- Kremen, W. S., Beck, A., Elman, J. A., Gustavson, D. E., Reynolds, C. A., Tu, X. M., Sanderson-Cimino, M. E., Panizzon, M. S., Vuoksimaa, E., Toomey, R., Fennema-Notestine, C., Hagler, D. J., Fang, B., Dale, A. M., Lyons, M. J., & Franz, C. E.
- Affiliations
- University of California San Diego (US)
- San Diego State University (US)
- University of California, Riverside (US)
- Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093;
- University of Helsinki (FI)
- Boston University (US)
- ORCID
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2019-01-22
- Volume
- 116
- Issue
- 6
- Pages
- 2021-2026
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC6369818
- OpenAlex
- W2913301193
- Cited by
- 180
- References
- 61
- Citations by year
- 2026: 18 · 2025: 27 · 2024: 32 · 2023: 21 · 2022: 30 · 2021: 25 · 2020: 16 · 2019: 9 · 2018: 2
- FWCI
- 23.51
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Työväentutkimus Vuosikirja (submittedVersion)
- Funders
- HHS | NIH | National Institute on Aging (AG050595, AG022381, AG022982, AG046413, AG047903, AG059329)
- Academy of Finland | Biotieteiden ja Ympäristön Tutkimuksen Toimikunta (314639)
- Vainio Foundation (No number)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Aging and Gerontology Research
- Keywords
- general intelligence, additional education, cognitive reserve, later-life cognition, occupational complexity, reverse causality, cortical surface area, Flynn effect, cognitive decline, dementia risk, educational quality
- MeSH terms
- Adolescent, Aged, Cognition, Cognition Disorders, Dementia, Education, Humans, Life Style, Longitudinal Studies, Male, Middle Aged, Young Adult, Cognitive Reserve, Cognitive Dysfunction
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