Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes

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Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

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Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects

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Evolving Concepts in the Pathogenesis of NASH: Beyond Steatosis and Inflammation

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Islet Inflammation Impairs the Pancreatic β-Cell in Type 2 Diabetes

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Acylcarnitines activate proinflammatory signaling pathways

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Toll‐like receptors in alcoholic liver disease, non‐alcoholic steatohepatitis and carcinogenesis

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The Influence of Dietary Fatty Acids on Immune Responses

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Toll-Like Receptor 2 and Palmitic Acid Cooperatively Contribute to the Development of Nonalcoholic Steatohepatitis Through Inflammasome Activation in Mice

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The Role of Gut Microbiota on Insulin Resistance

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Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization

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Saturated palmitic acid induces myocardial inflammatory injuries through direct binding to TLR4 accessory protein MD2

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TLR4 and Insulin Resistance

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Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome

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Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages

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Inflammasome-Mediated Secretion of IL-1β in Human Monocytes through TLR2 Activation; Modulation by Dietary Fatty Acids

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Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet

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Muscle inflammatory response and insulin resistance: synergistic interaction between macrophages and fatty acids leads to impaired insulin action

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Obesity decreases B cell responses in young and elderly individuals

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Inhibition of Foxo1 Protects Pancreatic Islet β-Cells Against Fatty Acid and Endoplasmic Reticulum Stress–Induced Apoptosis

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Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism

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Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors

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Saturated Fatty Acids in Obesity-Associated Inflammation

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METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARδ-dependent pathways in skeletal muscle of mice

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Defective NOD2 peptidoglycan sensing promotes diet‐induced inflammation, dysbiosis, and insulin resistance

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The Chaperone Balance Hypothesis: The Importance of the Extracellular to Intracellular HSP70 Ratio to Inflammation‐Driven Type 2 Diabetes, the Effect of Exercise, and the Implications for Clinical Management

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Coordinated Modulation of Energy Metabolism and Inflammation by Branched-Chain Amino Acids and Fatty Acids

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Protective role of oleic acid against cardiovascular insulin resistance and in the early and late cellular atherosclerotic process

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Insulin Resistance and Mitochondrial Dysfunction

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Toll-like receptors regulate B cell cytokine production in patients with diabetes

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BAIBA attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK–PPARδ-dependent pathway in mice

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Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet

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Proinflammatory NFkB signalling promotes mitochondrial dysfunction in skeletal muscle in response to cellular fuel overloading

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Getting the message across: mechanisms of physiological cross talk by adipose tissue

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Mechanisms by Which Skeletal Muscle Myokines Ameliorate Insulin Resistance

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Physiology and pathophysiology of liver lipid metabolism

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Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice

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Fatty acids and the endoplasmic reticulum in nonalcoholic fatty liver disease

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Asprosin attenuates insulin signaling pathway through PKCδ‐activated ER stress and inflammation in skeletal muscle

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Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle

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Constitutive STAT3 Phosphorylation Contributes to Skeletal Muscle Insulin Resistance in Type 2 Diabetes

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Acute Modulation of Toll-Like Receptors by Insulin

Ghanim, H., Mohanty, P., Deopurkar, R., Sia, C. L., Korzeniewski, K., Abuaysheh, S., Chaudhuri, A., & Dandona, P. (2008) · Diabetes Care · doi:10.2337/dc08-0561 · Cited by 125

Receptor for Advanced Glycation End Products Regulates Adipocyte Hypertrophy and Insulin Sensitivity in Mice

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Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide

Hajduch, É., Turban, S., Lièpvre, X. L., Lay, S. L., Lipina, C., Dimopoulos, N., Dugail, I., & Hundal, H. S. (2008) · Biochemical Journal · doi:10.1042/bj20070936 · Cited by 119

Elevated NF-κB Activation Is Conserved in Human Myocytes Cultured From Obese Type 2 Diabetic Patients and Attenuated by AMP-Activated Protein Kinase

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Absence of Tlr2 protects against high-fat diet-induced inflammation and results in greater insulin-stimulated glucose transport in cultured adipocytes

Davis, J. E., Braucher, D. R., Walker‐Daniels, J., & Spurlock, M. E. (2010) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2009.12.008 · Cited by 109

Fatty acid receptors as new therapeutic targets for diabetes

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NOD2 Activation Induces Muscle Cell-Autonomous Innate Immune Responses and Insulin Resistance

Tamrakar, A. K., Schertzer, J. D., Chiu, T. T., Foley, K. P., Bilan, P. J., Philpott, D. J., & Klip, A. (2010) · Endocrinology · doi:10.1210/en.2010-0437 · Cited by 107

Dihydromyricetin improves skeletal muscle insulin sensitivity by inducing autophagy via the AMPK-PGC-1α-Sirt3 signaling pathway

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Updating the effects of fatty acids on skeletal muscle

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NOD1 activation induces proinflammatory gene expression and insulin resistance in 3T3-L1 adipocytes

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Inhibition of pattern recognition receptor-mediated inflammation by bioactive phytochemicals

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Plant-Based Nutrition: Exploring Health Benefits for Atherosclerosis, Chronic Diseases, and Metabolic Syndrome—A Comprehensive Review

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From Obesity-Induced Low-Grade Inflammation to Lipotoxicity and Mitochondrial Dysfunction: Altered Multi-Crosstalk between Adipose Tissue and Metabolically Active Organs

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Renal Lipotoxicity-Associated Inflammation and Insulin Resistance Affects Actin Cytoskeleton Organization in Podocytes

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Fatty acid-induced NF-κB activation and insulin resistance in skeletal muscle are chain length dependent

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Citrus flavonoid naringenin inhibits TLR2 expression in adipocytes

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Mangiferin Improved Palmitate-Induced-Insulin Resistance by Promoting Free Fatty Acid Metabolism in HepG2 and C2C12 Cells via PPAR α : Mangiferin Improved Insulin Resistance

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