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A comprehensive review on recent preparation techniques of liposomes

Has, C., Sunthar, P.·2020·Journal of Liposome Research

Abstract

Liposomes (or lipid vesicles) are a versatile platform as carriers for the delivery of the drugs and other macromolecules into human and animal bodies. Though the method of using liposomes has been known since 1960s, and major developments and commercialization of liposomal formulations took place in the late nineties (or early part of this century), newer methods of liposome synthesis and drug encapsulation continue to be an active area of research. With the developments in related fields, such as electrohydrodynamics and microfluidics, and a growing understanding of the mechanisms of lipid assembly from colloidal and intermolecular forces, liposome preparation techniques have been enriched and more predictable than before. This has led to better methods that can also scale at an industrial production level. In this review, we present several novel methods that were introduced over the last decade and compare their advantages over conventional methods. Researchers beginning to explore liposomal formulations will find this resource useful to give an overall direction for an appropriate choice of method. Where possible, we have also provided the known mechanisms behind the preparation methods.

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Metadata

Authors
Has, C., & Sunthar, P.
Venue
Journal of Liposome Research
Published
2019-09-27
Volume
30
Issue
4
Pages
336-365
ISSN
  • 0898-2104 (ISSN-L)
  • 1532-2394
OpenAlex
W2976133514
Cited by
357
References
213
FWCI
8.03
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A comprehensive review on recent preparation techniques of liposomes. https://app.cochat.ai/papers/10.1080/08982104.2019.1668010
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Has, C., & Sunthar, P. (2020). A comprehensive review on recent preparation techniques of liposomes. Journal of Liposome Research. https://doi.org/10.1080/08982104.2019.1668010

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