Cited by 62Non-Invasive Vital Sign MonitoringCardiovascular Health and Disease PreventionHeart Rate Variability and Autonomic Control

Photoplethysmographic signal waveform index for detection of increased arterial stiffness

Pilt, K, Meigas, K, Ferenets, R, Temitski, K, Viigimaa, M·2014·Physiological Measurement

Abstract

The aim of this research was to assess the validity of the photoplethysmographic (PPG) waveform index PPGAI for the estimation of increased arterial stiffness. For this purpose, PPG signals were recorded from 24 healthy subjects and from 20 type II diabetes patients. The recorded PPG signals were processed with the analysis algorithm developed and the waveform index PPGAI similar to the augmentation index (AIx) was calculated. As a reference, the aortic AIx was assessed and normalized for a heart rate of 75 bpm (AIx@75) by a SphygmoCor device. A strong correlation (r = 0.85) between the PPGAI and the aortic AIx@75 and a positive correlation of both indices with age were found. Age corrections for the indices PPGAI and AIx@75 as regression models from the signals of healthy subjects were constructed. Both indices revealed a significant difference between the groups of diabetes patients and healthy controls. However, the PPGAI provided the best statistical discrimination for the group of subjects with increased arterial stiffness. The waveform index PPGAI based on the inexpensive PPG technology can be considered as a perspective measure of increased arterial stiffness estimation in clinical screenings.

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Crossref · 10.1088/0967-3334/35/10/2027

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Authors
Pilt, K., Meigas, K., Ferenets, R., Temitski, K., & Viigimaa, M.
Affiliations
Tallinn University of Technology (EE)
Venue
Physiological Measurement
Published
2014-09-19
Volume
35
Issue
10
Pages
2027-2036
ISSN
  • 0967-3334 (ISSN-L)
  • 1361-6579
OpenAlex
W2036371089
Cited by
62
References
36
Citations by year
2026: 5 · 2025: 5 · 2024: 6 · 2023: 10 · 2022: 11 · 2021: 1 · 2020: 6 · 2019: 3 · 2018: 4 · 2017: 6 · 2016: 4 · 2014: 1
FWCI
1.90
Type
journal article
Language
en
Open access
closed
Locations
  • Physiological Measurement (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • European Commission
  • National Institutes of Health
  • European Regional Development Fund
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Keywords
photoplethysmography, arterial stiffness, augmentation index, type 2 diabetes, aortic augmentation index, age correction, PPG signal analysis
MeSH terms
Adult, Aged, Aging, Algorithms, Diabetes Mellitus, Type 2, Female, Heart Rate, Humans, Male, Middle Aged, Signal Processing, Computer-Assisted, Case-Control Studies, Photoplethysmography, Young Adult, Vascular Stiffness

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