Fresh Mango Consumption Promotes Greater Satiety and Improves Postprandial Glucose and Insulin Responses in Healthy Overweight and Obese Adults
Abstract
Mangos are an understudied fruit rich in fiber and polyphenols that have been linked to better metabolic outcomes and promotion of satiety. The purpose of this study was to examine the effect of mango consumption on postprandial glucose, insulin, and satiety responses. Using a randomized crossover study design, 23 overweight and obese men and women consumed 100 kcal snacks of fresh mangos or isocaloric low-fat cookies on two separate occasions. Insulin and satiety hormones were measured at baseline and 45 min post-snack consumption. Glucose was measured at baseline, 30, 60, 90, and 120 min after snack consumption. Satiety questionnaires were completed at baseline and every 20 min for 120 min post-consumption. Both mangos and low-fat cookies increased insulin, with a significantly lower increase for mangos compared with low-fat cookies at 45 min post-snack consumption ( P ≤ .05). Glucose increased at 30 min for both snacks; however, the increase was significantly higher for low-fat cookie consumption ( P ≤ .05). Cholecystokinin increased after mangos and low-fat cookie consumption ( P ≤ .05); however, no differences were detected between the snacks. Adiponectin increased after mango consumption ( P ≤ .05) but not after low-fat cookies. Mango consumption reduced hunger, anticipated food consumption and thirst, and increased feelings of fullness ( P ≤ .05). Low-fat cookie consumption increased fullness for a shorter time period and did not reduce participants' desire to eat. These results suggest that relative to a refined cookie snack, mangos promote greater satiety and improve postprandial glycemic responses. Future research on long-term effects of mango consumption on food intake, weight control, and glucose homeostasis is warranted. Clinical Trial Registration number: #NCT03957928.
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Pinneo et al. measured satiety hormones only at 45 min after consumption.
“However, the study has a limitation because it measures satiety hormones at only 45 min after consumption”
From Mangifera indica L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review (2023) · cites this paper as [8]
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- Authors
- Pinneo, S., O'Mealy, C., Rosas Jr., M., Tsang, M., Liu, C., Kern, M., Hooshmand, S., & Hong, M. Y.
- Affiliations
- San Diego State University (US)
- School of Exercise and Nutritional Sciences, San Diego State University, San Diego, California, USA.
- Corresponding author
- Hong, Mee Young
- Venue
- Journal of Medicinal Food
- Publisher
- SAGE Publications
- Published
- 2021-11-23
- Volume
- 25
- Issue
- 4
- Pages
- 381-388
- ISSN
- 1096-620X (ISSN-L)
- 1557-7600
- OpenAlex
- W3216728029
- Cited by
- 19
- References
- 43
- Citations by year
- 2026: 3 · 2025: 7 · 2023: 8 · 2022: 1
- FWCI
- 2.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Medicinal Food (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Mangiferin and Mango Extracts
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
- Keywords
- mango, satiety, postprandial blood glucose, insulin response, overweight, obesity, cholecystokinin, adiponectin, hunger, fruit consumption, glucose homeostasis, weight management
- MeSH terms
- Adult, Blood Glucose, Energy Intake, Female, Glucose, Humans, Insulin, Male, Obesity, Satiation, Cross-Over Studies, Postprandial Period, Mangifera, Overweight, Snacks
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