Protein supplementation improves muscle mass and physical performance in undernourished prefrail and frail elderly subjects: A randomized, double-blind, placebo-controlled trial

Frailty in Older Adults: Evidence for a Phenotype

Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907 · see citing works

The Timed “Up & Go”: A Test of Basic Functional Mobility for Frail Elderly Persons

Podsiadlo, D., & Richardson, S. (1991) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1991.tb01616.x · Cited by 14,418 · see citing works

A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission

Guralnik, J. M., Simonsick, E. M., Ferrucci, L., Glynn, R. J., Berkman, L. F., Blazer, D. G., Scherr, P. A., & Wallace, R. B. (1994) · Journal of Gerontology · doi:10.1093/geronj/49.2.m85 · Cited by 9,792 · see citing works

The Loss of Skeletal Muscle Strength, Mass, and Quality in Older Adults: The Health, Aging and Body Composition Study

Goodpaster, B. H., Park, S. W., Harris, T. B., Kritchevsky, S. B., Nevitt, M., Schwartz, A. V., Simonsick, E. M., Tylavsky, F. A., Visser, M., Newman, A. B., et al. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.10.1059 · Cited by 3,083 · see citing works

The mini nutritional assessment (MNA) and its use in grading the nutritional state of elderly patients

Vellas, B., Guigoz, Y., Garry, P. J., Nourhashemi, F., Bennahum, D., Lauque, S., & Albarede, J.-L. (1999) · Nutrition · doi:10.1016/s0899-9007(98)00171-3 · Cited by 2,161 · see citing works

Protein intake and exercise for optimal muscle function with aging: Recommendations from the ESPEN Expert Group

Deutz, N. E. P., Bauer, J. M., Barazzoni, R., Biolo, G., Boirie, Y., Bosy-Westphal, A., Cederholm, T., Cruz-Jentoft, A., Krznariç, Z., Nair, K. S., et al. (2014) · Clinical Nutrition · doi:10.1016/j.clnu.2014.04.007 · Cited by 1,738 · see citing works

A CENTRAL LIMIT THEOREM AND A STRONG MIXING CONDITION

Rosenblatt, M. (1956) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.42.1.43 · Cited by 1,405 · see citing works

A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults

Morton, R. W., Murphy, K. T., McKellar, S. R., Schoenfeld, B. J., Henselmans, M., Helms, E., Aragon, A. A., Devries, M. C., Banfield, L., Krieger, J. W., et al. (2018) · British Journal of Sports Medicine · doi:10.1136/bjsports-2017-097608 · Cited by 1,154 · see citing works

Protein Ingestion to Stimulate Myofibrillar Protein Synthesis Requires Greater Relative Protein Intakes in Healthy Older Versus Younger Men

Moore, D. R., Churchward-Venne, T. A., Witard, O., Breen, L., Burd, N. A., Tipton, K. D., & Phillips, S. M. (2015) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glu103 · Cited by 770 · see citing works

Nutritional, Physical, Cognitive, and Combination Interventions and Frailty Reversal Among Older Adults: A Randomized Controlled Trial

Ng, T. P., Feng, L., Nyunt, M. S. Z., Feng, L., Niti, M., Tan, B. Y., Chan, G., Khoo, S. A., Chan, S. M., Yap, P. L. K., et al. (2015) · The American Journal of Medicine · doi:10.1016/j.amjmed.2015.06.017 · Cited by 726 · see citing works

Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men

Pennings, B., Boirie, Y., Senden, J. M., Gijsen, A. P., Kuipers, H., & van Loon, L. J. (2011) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.008102 · Cited by 656 · see citing works

Nutritional determinants of frailty in older adults: A systematic review

Lorenzo‐López, L., Maseda, A., de Labra, C., Regueiro-Folgueira, L., Rodríguez-Villamil, J. L., & Millán-Calentí, J. C. (2017) · BMC Geriatrics · doi:10.1186/s12877-017-0496-2 · Cited by 604 · see citing works

Effect of Dietary Protein on Bone Loss in Elderly Men and Women: The Framingham Osteoporosis Study

Hannan, M. T., Tucker, K. L., Dawson-Hughes, B., Cupples, L. A., Felson, D. T., & Kiel, D. P. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.12.2504 · Cited by 536 · see citing works

Low Nutrient Intake Is an Essential Component of Frailty in Older Persons

Bartali, B., Frongillo, E. A., Bandinelli, S., Lauretani, F., Semba, R. D., Fried, L. P., & Ferrucci, L. (2006) · The Journals of Gerontology Series A · doi:10.1093/gerona/61.6.589 · Cited by 495 · see citing works

Protein Supplementation Improves Physical Performance in Frail Elderly People: A Randomized, Double-Blind, Placebo-Controlled Trial

Tieland, M., van de Rest, O., Dirks, M. L., van der Zwaluw, N., Mensink, M., van Loon, L. J. C., & de Groot, L. C. P. G. M. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.07.005 · Cited by 446 · see citing works

Differences among skeletal muscle mass indices derived from height-, weight-, and body mass index-adjusted models in assessing sarcopenia

Kim, K. M., Jang, H. C., & Lim, S. K. (2016) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2016.015 · Cited by 404 · see citing works

The aging kidney

Zhou, X. J., Rakheja, D., Yu, X., Saxena, R., Vaziri, N. D., & Silva, F. G. (2008) · Kidney International · doi:10.1038/ki.2008.319 · Cited by 396 · see citing works

Epidemiology of sarcopenia and insight into possible therapeutic targets

Dennison, E. M., Sayer, A. A., & Cooper, C. C. (2017) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2017.60 · Cited by 296 · see citing works

The Role of Milk- and Soy-Based Protein in Support of Muscle Protein Synthesis and Muscle Protein Accretion in Young and Elderly Persons

Phillips, S. M., Tang, J. E., & Moore, D. R. (2009) · Journal of the American College of Nutrition · doi:10.1080/07315724.2009.10718096 · Cited by 243 · see citing works

Sarcopenia: a major modifiable cause of frailty in the elderly.

Roubenoff, R. (2000) · PubMed · Cited by 228 · see citing works

Effects of Exercise and Milk Fat Globule Membrane (MFGM) Supplementation on Body Composition, Physical Function, and Hematological Parameters in Community-Dwelling Frail Japanese Women: A Randomized Double Blind, Placebo-Controlled, Follow-Up Trial

Kim, H., Suzuki, T., Kim, M., Kojima, N., Ota, N., Shimotoyodome, A., Hase, T., Hosoi, E., & Yoshida, H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0116256 · Cited by 211 · see citing works

Preventive Effect of Protein-Energy Supplementation on the Functional Decline of Frail Older Adults With Low Socioeconomic Status: A Community-Based Randomized Controlled Study

Kim, C.-O., & Lee, K.-R. (2013) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/gls167 · Cited by 184 · see citing works

Effects of an Oral Nutritional Supplementation Plus Physical Exercise Intervention on the Physical Function, Nutritional Status, and Quality of Life in Frail Institutionalized Older Adults: The ACTIVNES Study

Abizanda, P., López, M. D., García, V. P., Estrella, J. D. D., González, Á. D. S., Vilardell, N. B., & Torres, K. A. (2015) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2015.02.005 · Cited by 172 · see citing works

Low-Dose Creatine Combined with Protein during Resistance Training in Older Men

CANDOW, D. G., LITTLE, J. P., CHILIBECK, P. D., ABEYSEKARA, S., ZELLO, G. A., KAZACHKOV, M., CORNISH, S. M., & YU, P. H. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318176b310 · Cited by 168 · see citing works

Frailty, osteoporosis and hip fracture: Causes, consequences and therapeutic perspectives

Rolland, Y., van Kan, G. A., Benetos, A., Blain, H., Bonnefoy, M., Chassagne, P., Jeandel, C., Laroche, M., Nourhashémi, F., Orcel, P., et al. (2008) · The journal of nutrition health & aging · doi:10.1007/bf02982665 · Cited by 144 · see citing works

Effects of food fortification on nutritional and functional status in frail elderly nursing home residents at risk of malnutrition

Smoliner, C., Norman, K., Scheufele, R., Hartig, W., Pirlich, M., & Lochs, H. H. (2008) · Nutrition · doi:10.1016/j.nut.2008.06.024 · Cited by 144 · see citing works

Prevalence and Outcomes of Frailty in Korean Elderly Population: Comparisons of a Multidimensional Frailty Index with Two Phenotype Models

Jung, H., Kim, S., Ahn, S., Lim, J., Han, J.-W., Kim, T. H., Kim, K., Kim, K.-I., & Kim, C.-H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087958 · Cited by 122 · see citing works

The Effect of Resistance Training and Different Sources of Postexercise Protein Supplementation on Muscle Mass and Physical Capacity in Sarcopenic Elderly Men

Maltais, M. L., Ladouceur, J. P., & Dionne, I. J. (2016) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000001255 · Cited by 116 · see citing works

The Effect of a Whey Protein Supplement on Bone Mass in Older Caucasian Adults

Kerstetter, J. E., Bihuniak, J. D., Brindisi, J., Sullivan, R., Mangano, K. M., Larocque, S., Kotler, B. M., Simpson, C. A., Cusano, A. M., Gaffney‐Stomberg, E., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-3792 · Cited by 84 · see citing works

The Validity and Reliability of Korean Frailty Index

Hwang, H. S., Kwon, I. S., Park, B., Cho, B., Yoon, J. L., & Won, C. W. (2010) · Journal of the Korean Geriatrics Society · doi:10.4235/jkgs.2010.14.4.191 · Cited by 84 · see citing works

Reference Values of Skeletal Muscle Mass for Korean Children and Adolescents Using Data from the Korean National Health and Nutrition Examination Survey 2009-2011

Kim, K., Hong, S., & Kim, E. Y. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153383 · Cited by 78 · see citing works

Insufficient amounts and inadequate distribution of dietary protein intake in apparently healthy older adults in a developing country: implications for dietary strategies to prevent sarcopenia

Alemán-Mateo, H., Valenzuela, R. E. R., Ponce, Figueroa, G. G. M., Muro, A., & Carreón, R. (2013) · Clinical Interventions in Aging · doi:10.2147/cia.s49810 · Cited by 70 · see citing works

Starting Construction of Frailty Cohort for Elderly and Intervention Study

Won, C. W., Lee, Y., Choi, J., Kim, K. W., Park, Y., Park, H., Oh, I., Ga, H., Kim, Y. S., Jang, H. C., et al. (2016) · Annals of Geriatric Medicine and Research · doi:10.4235/agmr.2016.20.3.114 · Cited by 56 · see citing works

Plant Proteins: Assessing Their Nutritional Quality and Effects on Health and Physical Function

Hertzler, S. R., Lieblein-Boff, J. C., Weiler, M., & Allgeier, C. (2020) · Nutrients · doi:10.3390/nu12123704 · Cited by 594 · see citing works

Nutrition and Sarcopenia—What Do We Know?

Ganapathy, A., & Nieves, J. W. (2020) · Nutrients · doi:10.3390/nu12061755 · Cited by 355 · see citing works

Nutrition Management in Older Adults with Diabetes: A Review on the Importance of Shifting Prevention Strategies from Metabolic Syndrome to Frailty

Tamura, Y., Omura, T., Toyoshima, K., & Araki, A. (2020) · Nutrients · doi:10.3390/nu12113367 · Cited by 239 · see citing works

Healthy Aging—Nutrition Matters: Start Early and Screen Often

Roberts, S. B., Silver, R. E., Das, S. K., Fielding, R. A., Gilhooly, C. H., Jacques, P. F., Kelly, J. M., Mason, J. B., McKeown, N. M., Reardon, M. A., et al. (2021) · Advances in Nutrition · doi:10.1093/advances/nmab032 · Cited by 133 · see citing works

Approaches to the diagnosis and prevention of frailty

Woolford, S., Sohan, O., Dennison, E., Cooper, C., & Patel, H. (2020) · Aging Clinical and Experimental Research · doi:10.1007/s40520-020-01559-3 · Cited by 110 · see citing works

The intersection of frailty and metabolism

Mishra, M., Wu, J., Kane, A. E., & Howlett, S. E. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.03.012 · Cited by 95 · see citing works

Nutritional Assessment in Older Adults: MNA® 25 years of a Screening Tool & a Reference Standard for Care and Research; What Next?

Guigoz, Y., & Vellas, B. (2021) · The Journal of nutrition, health and aging · doi:10.1007/s12603-021-1601-y · Cited by 93 · see citing works

Whey Protein Supplementation with or without Vitamin D on Sarcopenia-Related Measures: A Systematic Review and Meta-Analysis

Nasimi, N., Sohrabi, Z., Nunes, E. A., Sadeghi, E., Jamshidi, S., Gholami, Z., Akbarzadeh, M., Faghih, S., Akhlaghi, M., & Phillips, S. M. (2023) · Advances in Nutrition · doi:10.1016/j.advnut.2023.05.011 · Cited by 80 · see citing works

Advances in nutritional supplementation for sarcopenia management

Liu, S., Zhang, L., & Li, S. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1189522 · Cited by 81 · see citing works

Frailty Predicts an Increased Risk of End-Stage Renal Disease with Risk Competition by Mortality among 165,461 Diabetic Kidney Disease Patients

Chao, C., Wang, J., Huang, J., Chan, D., & Chien, K. (2019) · Aging and Disease · doi:10.14336/ad.2019.0216 · Cited by 65 · see citing works

Factors influencing the efficacy of nutritional interventions on muscle mass in older adults: a systematic review and meta-analysis

Martin-Cantero, A., Reijnierse, E. M., Gill, B. M. T., & Maier, A. B. (2021) · Nutrition Reviews · doi:10.1093/nutrit/nuaa064 · Cited by 58 · see citing works

Optimum nutritional strategies for cardiovascular disease prevention and rehabilitation (BACPR)

Butler, T., Kerley, C. P., Altieri, N., Alvarez, J., Green, J., Hinchliffe, J., Stanford, D., & Paterson, K. (2020) · Heart · doi:10.1136/heartjnl-2019-315499 · Cited by 82 · see citing works

Effects of resistance exercise and whey protein supplementation on skeletal muscle strength, mass, physical function, and hormonal and inflammatory biomarkers in healthy active older men: a randomised, double-blind, placebo-controlled trial

Griffen, C., Duncan, M. J., Hattersley, J. G., Weickert, M. O., Dallaway, A., & Renshaw, D. W. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111651 · Cited by 57 · see citing works

Nutrition and Physical Activity Clinical Practice Guidelines for Older Adults Living with Frailty

Lorbergs, A. L., Prorok, J. C., Holroyd-Leduc, J. M., B̀ouchard, D. R., Giguere, A. M. C., Gramlich, L. M., Keller, H., Tang, A., Racey, M., Ali, M. U., et al. (2021) · The Journal of Frailty & Aging · doi:10.14283/jfa.2021.51 · Cited by 58 · see citing works

Is It Time to Reconsider the U.S. Recommendations for Dietary Protein and Amino Acid Intake?

Weiler, M. D., Hertzler, S. R., & Dvoretskiy, S. (2023) · Nutrients · doi:10.3390/nu15040838 · Cited by 55 · see citing works

Effects of Leucine-Enriched Whey Protein Supplementation on Physical Function in Post-Hospitalized Older Adults Participating in 12-Weeks of Resistance Training Program: A Randomized Controlled Trial

Amasene, M., Besga, A., Echeverria, I., Urquiza, M., Ruiz, J. R., Rodriguez‐Larrad, A., Aldámiz, M., Anaut, P., Irazusta, J., & Labayen, I. (2019) · Nutrients · doi:10.3390/nu11102337 · Cited by 51 · see citing works

Effectiveness of nutrition interventions and combined nutrition and physical activity interventions in older adults with frailty or prefrailty: a systematic review and meta-analysis

Racey, M., Ali, M. U., Sherifali, D., Fitzpatrick‐Lewis, D., Lewis, R., Jovkovic, M., Gramlich, L. M., Keller, H., Holroyd-Leduc, J. M., Giguere, A. M. C., et al. (2021) · CMAJ Open · doi:10.9778/cmajo.20200248 · Cited by 47 · see citing works

Protein Intake Recommendation for Korean Older Adults to Prevent Sarcopenia: Expert Consensus by the Korean Geriatric Society and the Korean Nutrition Society

Jung, H., Kim, S., Kim, I., Lim, J., Park, H.-S., Song, W., Yoo, H. J., Jang, H. C., Kim, K., Park, Y., et al. (2018) · Annals of Geriatric Medicine and Research · doi:10.4235/agmr.18.0046 · Cited by 47 · see citing works

Nutritional interventions for the management of frailty in older adults: systematic review and meta-analysis of randomized clinical trials

de Moraes, M. B., Avgerinou, C., Fukushima, F. B., & Vidal, E. I. D. O. (2020) · Nutrition Reviews · doi:10.1093/nutrit/nuaa101 · Cited by 46 · see citing works

Association of frailty with the incidence risk of cardiovascular disease and type 2 diabetes mellitus in long-term cancer survivors: a prospective cohort study

Cao, X., Yang, Z., Li, X., Chen, C., Hoogendijk, E. O., Zhang, J., Yao, N. A., Ma, L., Zhang, Y., Zhu, Y. L., et al. (2023) · BMC Medicine · doi:10.1186/s12916-023-02774-1 · Cited by 46 · see citing works

The Potential Role of Fish-Derived Protein Hydrolysates on Metabolic Health, Skeletal Muscle Mass and Function in Ageing

Lees, M. J., & Carson, B. P. (2020) · Nutrients · doi:10.3390/nu12082434 · Cited by 46 · see citing works

Daily Supplementation With Whey, Soy, or Whey-Soy Blended Protein for 6 Months Maintained Lean Muscle Mass and Physical Performance in Older Adults With Low Lean Mass

Li, C., Meng, H., Wu, S., Fang, A., Liao, G., Tan, X., Chen, P., Wang, X., Chen, S., & Zhu, H. (2021) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2021.01.006 · Cited by 43 · see citing works

Skeletal muscle wasting during neoadjuvant therapy as a prognosticator in patients with esophageal and esophagogastric junction cancer: A systematic review and meta-analysis

Wang, P., Wang, S., Li, X., Lin, G., Ma, Y., Xiao, R., Li, H., Qiu, M., & Yang, F. (2022) · International Journal of Surgery · doi:10.1016/j.ijsu.2021.106206 · Cited by 43 · see citing works

Effects of Exergames and Protein Supplementation on Body Composition and Musculoskeletal Function of Prefrail Community-Dwelling Older Women: A Randomized, Controlled Clinical Trial

Biesek, S., Vojciechowski, A. S., Filho, J. M., Ferreira, A. C. R. D. M., Borba, V. Z. C., Rabito, E. I., & Gomes, A. R. S. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18179324 · Cited by 44 · see citing works

Evenly Distributed Protein Intake over 3 Meals Augments Resistance Exercise–Induced Muscle Hypertrophy in Healthy Young Men

Yasuda, J., Tomita, T., Arimitsu, T., & Fujita, S. (2020) · The Journal of Nutrition · doi:10.1093/jn/nxaa101 · Cited by 41 · see citing works

Leucine-Enriched Protein Supplementation Increases Lean Body Mass in Healthy Korean Adults Aged 50 Years and Older: A Randomized, Double-Blind, Placebo-Controlled Trial

Kang, Y., Kim, N. H., Choi, Y. J., Lee, Y., Yun, J., Park, S. J., Park, H. S., Chung, Y., & Park, Y. K. (2020) · Nutrients · doi:10.3390/nu12061816 · Cited by 40 · see citing works

Relationships between sarcopenia, nutrient intake, and gut microbiota in Chinese community-dwelling older women

Yan, X., Li, H., Xie, R., Li, L., Ding, L., Cheng, X., Xu, J., Bai, L., & Qiao, Y. (2023) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2023.105063 · Cited by 38 · see citing works

Sex-and race-specific associations of protein intake with change in muscle mass and physical function in older adults: the Health, Aging, and Body Composition (Health ABC) Study

Elstgeest, L. E. M., Schaap, L. S., Heymans, M. W., Hengeveld, L. M., Naumann, E., Houston, D. K., Kritchevsky, S. B., Simonsick, E. M., Newman, A. B., Farsijani, S., et al. (2020) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqaa099 · Cited by 38 · see citing works

Physiological Systems in Promoting Frailty

Perazza, L. R., Brown‐Borg, H. M., & Thompson, L. V. (2022) · Comprehensive physiology · doi:10.1002/cphy.c210034 · Cited by 64 · see citing works

The Effects of Protein and Supplements on Sarcopenia in Human Clinical Studies: How Older Adults Should Consume Protein and Supplements

Jang, Y. J. (2022) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2210.10014 · Cited by 39 · see citing works

Protein Nutritional Support: The Classical and Potential New Mechanisms in the Prevention and Therapy of Sarcopenia

Zhang, J., Yu, Y., & Wang, J. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c00688 · Cited by 37 · see citing works

Plant-Based Proteins and Their Modification and Processing for Vegan Cheese Production

Kovačević, J., Bechtold, T., & Pham, T. (2024) · Macromol—A Journal of Macromolecular Research · doi:10.3390/macromol4010002 · Cited by 37 · see citing works

Diagnosis and Management of Frailty in Primary Health Care

Won, C. W. (2020) · Korean Journal of Family Medicine · doi:10.4082/kjfm.20.0122 · Cited by 34 · see citing works

Health Effects of Increasing Protein Intake Above the Current Population Reference Intake in Older Adults: A Systematic Review of the Health Council of the Netherlands

Hengeveld, L. M., de Goede, J., Afman, L. A., Bakker, S. J. L., Beulens, J. W. J., Blaak, E. E., Boersma, E. H., Geleijnse, J. M., van Goudoever, J. B., Hopman, M. T. E., et al. (2021) · Advances in Nutrition · doi:10.1093/advances/nmab140 · Cited by 35 · see citing works

Prevention and treatment of malnutrition in older adults living in long-term care or the community: an evidence-based nutrition practice guideline

Riddle, E., Munoz, N., Clark, K., Collins, N., Coltman, A., Nasrallah, L., Nishioka, S., Scollard, T., Simon, J. R., & Moloney, L. (2024) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2024.03.013 · Cited by 33 · see citing works

Dietary protein and amino acid intakes for mitigating sarcopenia in humans

He, W., Connolly, E. D., Cross, H. R., & Wu, G. (2024) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2024.2348549 · Cited by 37 · see citing works

The Effects of Cow-Milk Protein Supplementation in Elderly Population: Systematic Review and Narrative Synthesis

Zanini, B., Simonetto, A., Zubani, M., Castellano, M., & Gilioli, G. (2020) · Nutrients · doi:10.3390/nu12092548 · Cited by 35 · see citing works

Deciphering the protein digestion of meat products for the elderly by in vitro food oral processing and gastric dynamic digestion, peptidome analysis and modeling

Peyron, M., Sayd, T., Sicard, J., Mirade, P., Pinguet, J., Chambon, C., & Santé-Lhoutellier, V. (2021) · Food & Function · doi:10.1039/d1fo00969a · Cited by 32 · see citing works

Association of Protein Intake with Sarcopenia and Related Indicators Among Korean Older Adults: A Systematic Review and Meta-Analysis

Han, M., Woo, K.-S., & Kim, K. (2024) · Nutrients · doi:10.3390/nu16244350 · Cited by 31 · see citing works

Prevalence and risk factors of frailty in older adults with diabetes: A systematic review and meta-analysis

Liu, Y., Zhang, L., Li, X., Luo, A., Guo, S., Liu, X., Wei, X., Sun, Y., Wang, M., & Liao, L. (2024) · PLoS ONE · doi:10.1371/journal.pone.0309837 · Cited by 32 · see citing works

Physiological Systems in Promoting Frailty

Perazza, L. R., Brown‐Borg, H. M., & Thompson, L. V. (2022) · Comprehensive physiology · doi:10.1002/j.2040-4603.2022.tb00224.x · Cited by 30 · see citing works

Therapeutic advances in sarcopenia management: From traditional interventions to personalized medicine

Liu, X., Chen, X., & Cui, J. (2025) · Clinical Nutrition · doi:10.1016/j.clnu.2025.06.007 · Cited by 32 · see citing works

High Intensity Interval Training: A Potential Method for Treating Sarcopenia

Liu, Q., Xie, W., Luo, Y., Li, Y., Huang, W., Wu, Y., & Li, Y. (2022) · Clinical Interventions in Aging · doi:10.2147/cia.s366245 · Cited by 29 · see citing works

Systematic review with meta‐analysis: Nutritional screening and assessment tools in cirrhosis

Ney, M. S., Li, S., Vandermeer, B., Gramlich, L. M., Ismond, K. P., Raman, M., & Tandon, P. (2019) · Liver International · doi:10.1111/liv.14269 · Cited by 26 · see citing works

Dietary protein intake and changes in muscle mass measurements in community-dwelling middle-aged and older adults: A prospective cohort study

Chen, S., Lin, X., Ma, J., Li, M., Chen, Y., Fang, A., & Zhu, H. (2023) · Clinical Nutrition · doi:10.1016/j.clnu.2023.10.017 · Cited by 24 · see citing works

Chronic inflammation as a driving factor for sarcopenia: an update on pathophysiology and future therapeutic targets

Liang, Z., & Zhang, L. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1733798 · Cited by 26 · see citing works

Effectiveness and cost-effectiveness of personalised dietary advice aiming at increasing protein intake on physical functioning in community-dwelling older adults with lower habitual protein intake: rationale and design of the PROMISS randomised controlled trial

Reinders, I., Wijnhoven, H. A. H., Jyväkorpi, S. K., Suominen, M. H., Niskanen, R. T., Bosmans, J. E., Brouwer, I. A., Fluitman, K. S., Klein, M. C. A., Kuijper, L. D. J., et al. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-040637 · Cited by 24 · see citing works

Direct and Indirect Effects of COVID-19 in Frail Elderly: Interventions and Recommendations

Pizano-Escalante, M. G., Esparza, L. M. A., Nuño, K., Rodríguez-Romero, J. D. J., González-Torres, S., la Mora, D. A. L.-D., & Villagrán, Z. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11100999 · Cited by 24 · see citing works

The cost effectiveness of personalized dietary advice to increase protein intake in older adults with lower habitual protein intake: a randomized controlled trial

Reinders, I., Visser, M., Jyväkorpi, S. K., Niskanen, R. T., Bosmans, J. E., Ben, Â. J., Brouwer, I. A., Kuijper, L. D. J., Olthof, M. R., Pitkälä, K. H., et al. (2021) · European Journal of Nutrition · doi:10.1007/s00394-021-02675-0 · Cited by 23 · see citing works

Using Dietary Macronutrient Patterns to Predict Sarcopenic Obesity in Older Adults: A Representative Korean Nationwide Population-Based Study

Lee, J., Park, H. M., & Lee, Y. (2021) · Nutrients · doi:10.3390/nu13114031 · Cited by 23 · see citing works

Individually tailored nutritional guidance improved dietary intake of older family caregivers: a randomized controlled trial

Koponen, S., Nykänen, I., Savela, R., Välimäki, T. H., Suominen, A. L., & Schwab, U. (2022) · European Journal of Nutrition · doi:10.1007/s00394-022-02908-w · Cited by 21 · see citing works

Effect of protein supplementation on plasma sodium levels in the syndrome of inappropriate antidiuresis: a monocentric, open-label, proof-of-concept study—the TREASURE study

Monnerat, S., Atila, C., Baur, F., de Jesus, J. S., Refardt, J. C., Dickenmann, M., & Christ‐Crain, M. (2023) · European Journal of Endocrinology · doi:10.1093/ejendo/lvad108 · Cited by 21 · see citing works

Secondhand smoke is positively associated with pre-frailty and frailty in non-smoking older adults

Fu, Z., Zhou, T., Dong, F., Li, M., Lin, X., Ma, W., Song, Y., & Song, G. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.1095254 · Cited by 21 · see citing works

Nutritional management interventions and multi-dimensional outcomes in frail and pre-frail older adults: A systematic review and meta-analysis

Li, W., Wu, Z., Liao, X., Geng, D., Yang, J., Dai, M., & Talipti, M. (2024) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2024.105480 · Cited by 19 · see citing works

Cognitive Frailty and Aging: Clinical Characteristics, Pathophysiological Mechanisms, and Potential Prevention Strategies

Aguilar-Navarro, S. G., Mimenza-Alvarado, A. J., Yeverino-Castro, S. G., Caicedo-Correa, S. M., & Cano, C. A. (2024) · Archives of Medical Research · doi:10.1016/j.arcmed.2024.103106 · Cited by 19 · see citing works

2020 Korean Dietary Reference Intakes for Protein: Estimation of protein requirements and the status of dietary protein intake in the Korean population

Kim, E., Chung, S., Hwang, J., & Park, Y. J. (2022) · Journal of Nutrition and Health · doi:10.4163/jnh.2022.55.1.10 · Cited by 19 · see citing works

Demystifying Malnutrition to Improve Nutrition Screening and Assessment in Oncology

Corriveau, J., Alavifard, D., & Gillis, C. (2022) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2022.151336 · Cited by 19 · see citing works

Protein intake in older people

Kiesswetter, E., Sieber, C. C., & Volkert, D. (2020) · Zeitschrift für Gerontologie und Geriatrie · doi:10.1007/s00391-020-01723-4 · Cited by 19 · see citing works

Effects of protein supplementation and exercise on delaying sarcopenia in healthy older individuals in Asian and non-Asian countries: A systematic review and meta-analysis

Li, L., He, Y., Jin, N., He, L., & Liu, X. (2022) · Food Chemistry X · doi:10.1016/j.fochx.2022.100210 · Cited by 18 · see citing works

Effects of high-protein diet combined with exercise to counteract frailty in pre-frail and frail community-dwelling older adults: study protocol for a three-arm randomized controlled trial

Buhl, S. F., Beck, A. M., Christensen, B., & Caserotti, P. (2020) · Trials · doi:10.1186/s13063-020-04572-z · Cited by 17 · see citing works

Clinical Practice Guidelines for Managing Frailty in Community-Dwelling Korean Elderly Adults in Primary Care Settings

You, H., Kwon, Y., Kim, S. Y., Kim, Y., Kim, Y.-S., Kim, Y., Roh, Y. K., Park, B., Park, Y.-K., Park, C.-H., et al. (2021) · Korean Journal of Family Medicine · doi:10.4082/kjfm.21.0162 · Cited by 16 · see citing works

Sarcopenia and motoric cognitive risk syndrome: a moderated mediation model

Zhang, T., Zhang, Y., Lv, Z., & Xiang, J. (2022) · BMC Geriatrics · doi:10.1186/s12877-022-02802-4 · Cited by 16 · see citing works

Tailoring prehabilitation to address the multifactorial nature of functional capacity for surgery

Gillis, C., Coca-Martínez, M., & Mina, D. S. (2022) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.13050 · Cited by 17 · see citing works

Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity

Chae, M., Park, H. S., & Park, K. (2021) · Nutrition Research and Practice · doi:10.4162/nrp.2021.15.2.203 · Cited by 16 · see citing works

Perioperative cognition in association with malnutrition and frailty: a narrative review

Dammavalam, V. M., Murphy, J., Johnkutty, M., Elias, M., Corn, R., & Bergese, S. D. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1275201 · Cited by 15 · see citing works

Effects on physical performance of high protein intake for critically ill adult patients admitted to the intensive care unit: A retrospective propensity-matched analysis

Matsushima, S., Yoshida, M., Yokoyama, H., Watanabe, Y., Onodera, H., Wakatake, H., Saito, H., Kimura, M., & Shibata, S. (2021) · Nutrition · doi:10.1016/j.nut.2021.111407 · Cited by 14 · see citing works

Aging influences protein digestion, absorption and amino acid metabolism

Qiu, L., Huang, Q., Li, W., Zhang, Q., Zhou, J., Chen, J., Li, Y., Wang, R., Wang, P., Liu, S., et al. (2025) · Biogerontology · doi:10.1007/s10522-025-10289-w · Cited by 13 · see citing works

Adequate Protein Intake on Comprehensive Frailty in Older Adults: Kyoto-Kameoka Study

Nanri, H., Watanabe, D., Yoshida, T., Yoshimura, E., Okabe, Y., Ono, M., Koizumi, T., Kobayashi, H., Fujita, H., Kimura, M., et al. (2022) · The journal of nutrition health & aging · doi:10.1007/s12603-022-1740-9 · Cited by 13 · see citing works

Association between masseter muscle volume, nutritional status, and cognitive status in older people

Lin, C., Liu, L.-K., Chen, L., & Fuh, J. (2023) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2023.105038 · Cited by 13 · see citing works

Nutritional Intervention Improves Muscle Mass and Physical Performance in the Elderly in the Community: A Systematic Review and Meta-Analysis

Ren, Y., Lu, A., Wang, B., & Wang, C. (2023) · Life · doi:10.3390/life14010070 · Cited by 13 · see citing works

The effect of dose, frequency, and timing of protein supplementation on muscle mass in older adults: A systematic review and meta-analysis

Hettiarachchi, J., Reijnierse, E. M., Kew, N., Fetterplace, K., Tan, S., & Maier, A. B. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102325 · Cited by 13 · see citing works

Polypharmacy and Lack of Joy Are Related to Physical Frailty among Northern Japanese Community-Dwellers from the ORANGE Cohort Study

Kume, Y., Takahashi, T., Itakura, Y., Lee, S., Makizako, H., Ono, T., Shimada, H., & Ota, H. (2021) · Gerontology · doi:10.1159/000511986 · Cited by 13 · see citing works

Protein Nutritional Status and Frailty: A Mendelian Randomization Study

Tomata, Y., Wang, Y., Hägg, S., & Jylhävä, J. (2021) · Journal of Nutrition · doi:10.1093/jn/nxab348 · Cited by 13 · see citing works

Muscle-Related Effect of Whey Protein and Vitamin D3 Supplementation Provided before or after Bedtime in Males Undergoing Resistance Training

Chen, Y., Liang, Y., Guo, H., Meng, K., Qiu, J., & Benardot, D. (2022) · Nutrients · doi:10.3390/nu14112289 · Cited by 13 · see citing works

Modulation of frailty syndrome by diet: A review of evidence from mouse studies

Mitchell, S. J., Mitchell, G. J., & Mitchell, J. R. (2019) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2019.04.003 · Cited by 11 · see citing works

Adequate protein intake in older adults in the context of frailty: cross-sectional results of the Nutrition and Health Survey in Taiwan 2014–2017

Wu, S.-Y., Yeh, N.-H., Chang, H., Wang, C.-F., Hung, S.-Y., Wu, S., & Pan, W. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab070 · Cited by 13 · see citing works

Effectiveness of whey protein supplementation on muscle strength and physical performance of older adults: A systematic review and meta-analysis of randomized clinical trials

Al-Rawhani, A. H., Adznam, S. N., Abu Zaid, Z., Md. Yusop, N. B., M. Sallehuddin, H., & Alshawsh, M. A. (2024) · Clinical Nutrition · doi:10.1016/j.clnu.2024.08.033 · Cited by 13 · see citing works

Protein Restriction in Metabolic Health: Lessons from Rodent Models

Na, K., & Park, Y. J. (2024) · Nutrients · doi:10.3390/nu16020229 · Cited by 12 · see citing works

Oral Protein Supplements Might Improve Nutritional Status and Quality of Life in Elderly Patients after Standard Pancreatic Resection

Lee, N. R., Hwang, H. K., Lee, H., & Kang, C. M. (2024) · Nutrients · doi:10.3390/nu16172988 · Cited by 12 · see citing works

Two dietary advice strategies to increase protein intake among community-dwelling older adults: A feasibility study

Reinders, I., Visser, M., & Wijnhoven, H. A. H. (2020) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2020.02.020 · Cited by 12 · see citing works

Towards developing a Core Outcome Set for malnutrition intervention studies in older adults: a scoping review to identify frequently used research outcomes

Visser, M., Mendonça, N., Avgerinou, C., Cederholm, T., Cruz-Jentoft, A. J., Goisser, S., Kiesswetter, E., Siebentritt, H. M., Volkert, D., & Torbahn, G. (2022) · European Geriatric Medicine · doi:10.1007/s41999-022-00617-5 · Cited by 12 · see citing works

Regional differences in the associations of diet quality, obesity, and possible sarcopenia using the seventh Korea National Health and Nutrition Examination Survey (2016-2018)

Lee, H., & Park, S. (2023) · Epidemiology and Health · doi:10.4178/epih.e2023059 · Cited by 13 · see citing works

Amount of Protein Required to Improve Muscle Mass in Older Adults

Kim, D., & Park, Y. (2020) · Nutrients · doi:10.3390/nu12061700 · Cited by 12 · see citing works

A review of recent evidence of dietary protein intake and health

Park, Y. J., Chung, S., Hwang, J., Shon, J., & Kim, E. (2022) · Nutrition Research and Practice · doi:10.4162/nrp.2022.16.s1.s37 · Cited by 12 · see citing works

Impact of food-based fortification on nutritional outcomes and acceptability in older adults: systematic literature review

Geny, A., Petitjean, M., Wymelbeke-Delannoy, V. V., & Sulmont‐Rossé, C. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1232502 · Cited by 11 · see citing works

Frailty knowledge level and its influencing factors among older adults in China

Zhou, T., Qu, Z., Song, G., Wu, X., Zhang, X. L., Wang, A., & Tang, X. (2023) · Geriatric Nursing · doi:10.1016/j.gerinurse.2023.01.004 · Cited by 11 · see citing works

Association between Sarcopenia and Energy and Protein Intakes in Community-dwelling Elderly

Na, W., Oh, D., Hwang, S., Chung, B., & Sohn, C. (2022) · 대한지역사회영양학회지 · doi:10.5720/kjcn.2022.27.4.286 · Cited by 10 · see citing works

Clinical Practice Guideline for Frailty Applicable in Primary Care Setting

You, H., Kwon, Y., Kim, S. Y., Kim, Y., Kim, Y.-S., Kim, Y., Roh, Y. K., Park, B., Park, Y.-K., Park, C.-H., et al. (2021) · Korean Journal of Family Practice · doi:10.21215/kjfp.2021.11.4.223 · Cited by 10 · see citing works

Evaluating the Effect of a Home-Delivered Meals Service on the Physical and Psychological Wellbeing of a UK Population of Older Adults – A Pilot and Feasibility Study

O’Leary, M. F., Barreto, M., & Bowtell, J. L. (2019) · Journal of Nutrition in Gerontology and Geriatrics · doi:10.1080/21551197.2019.1684417 · Cited by 10 · see citing works

Effectiveness of Protein-Enriched Oral Nutritional Supplements on Muscle Function in Middle-Aged and Elderly Women: A Randomized Controlled Trial

Kang, M., Rho, H., Kim, M., Lee, M., Lim, Y., Chon, J., & Lim, H. (2025) · The Journal of nutrition, health and aging · doi:10.1016/j.jnha.2025.100508 · Cited by 10 · see citing works

Effects of protein supplementation on muscle wasting disorders: A brief update of the evidence

Kirk, B., Iuliano, S., Daly, R. M., & Duque, G. (2020) · Australian Journal on Ageing · doi:10.1111/ajag.12853 · Cited by 9 · see citing works

Reinforcement Effects of Social Network Intervention during Nutritional Supplementation in Frail Older Adults

Kim, C.-O., Jeong, Y.-H., Park, Y., Bae, J.-S., Kwon, Y., Cho, M. H., Yoo, C. H., & Lee, K. (2021) · Gerontology · doi:10.1159/000514676 · Cited by 9 · see citing works

Effectiveness of a Per-Meal Protein Prescription and Nutrition Education with versus without Diet Coaching on Dietary Protein Intake and Muscle Health in Middle-Aged Women

Jackson, K. L., Gropper, S. S., Hunt, D., D’Avolio, D., & Newman, D. (2022) · Nutrients · doi:10.3390/nu14020375 · Cited by 8 · see citing works

Regional differences in protein intake and protein sources of Korean older adults and their association with metabolic syndrome using the 2016–2019 Korea National Health and Nutrition Examination Surveys: a cross-sectional study

Lee, Y.-S., & Lee, Y. (2024) · 대한지역사회영양학회지 · doi:10.5720/kjcn.2024.29.3.173 · Cited by 7 · see citing works

Sarcopenia: an Aging Perspective and Management Options

Teixeira, A. M., Nosrani, S. E., Parvani, M., Viola, J., & Mohammadi, S. (2025) · International Journal of Sports Medicine · doi:10.1055/a-2577-2577 · Cited by 7 · see citing works

Effects of 12-Week Dietary Inflammatory Index-Based Dietary Education on Frailty Status in Frail Patients with Colorectal Cancer: A Randomized Controlled Trial

Wang, Y., Liu, Y., Cheng, L., He, J., Cheng, X., Lin, X., Miao, X., Huang, Z., & Xia, S. (2025) · Nutrients · doi:10.3390/nu17132203 · Cited by 7 · see citing works

Combined Protein, Probiotics, and Exercise Therapy for Sarcopenia: A Comprehensive Review

Kwon, R. J., Mijan, M. A., Son, S. M., Yoo, W., & Kim, T. (2025) · Cells · doi:10.3390/cells14171375 · Cited by 7 · see citing works

Dietary factors and nutritional guidelines for sarcopenia in older adults: a narrative review

Heo, S., & Yang, S. J. (2025) · 대한지역사회영양학회지 · doi:10.5720/kjcn.2025.00360 · Cited by 7 · see citing works

The feasibility of a 6‐month dietary intervention aiming to increase protein intake among community‐dwelling older adults with low habitual protein intake: A secondary analysis of the PROMISS randomised controlled trial

Niskanen, R. T., Reinders, I., Wijnhoven, H. A. H., Hyvönen, A., Pols‐Vrijmoeth, M., Trommel‐Bout, M., Visser, M., Pitkälä, K. H., Suominen, M. H., Öhman, H., et al. (2023) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.13197 · Cited by 7 · see citing works

Daily supplementation of lesser mealworm protein for 11-weeks increases skeletal muscle mass in physically active older adults

Koopmans, L., Spoelder, M., Bongers, C. C. W. G., Eijsvogels, T. M. H., & Hopman, M. T. E. (2024) · The journal of nutrition health & aging · doi:10.1016/j.jnha.2024.100364 · Cited by 7 · see citing works

EFFECTS OF PROTEIN SUPPLEMENTATION ON FRAILTY AND SARCOPENIA IN PRE‐FRAIL AND FRAIL ELDERLY: STUDY PROTOCAL FOR A DOSE‐RESPONSE, DOUBLE‐BLIND, RANDOMIZED PLACEBO‐CONTROLLED TRAIL

Park, Y., & Kwon, S. (2017) · The FASEB Journal · doi:10.1096/fasebj.31.1_supplement.645.1

Efficacy of protein supplementation on frailty improvement, muscle strength, and physical performance among pre-frail older adults in Selangor, Malaysia

Al-Rawhani, A. H. N. (2024) · Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)

Protein Supplementation Improves Physical Performance in Frail Elderly People: A Randomized, Double-Blind, Placebo-Controlled Trial

Tieland, M., van de Rest, O., Dirks, M. L., van der Zwaluw, N., Mensink, M., van Loon, L. J. C., & de Groot, L. C. P. G. M. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.07.005 · Cited by 446 · see citing works

Protein Supplementation Increases Muscle Mass Gain During Prolonged Resistance-Type Exercise Training in Frail Elderly People: A Randomized, Double-Blind, Placebo-Controlled Trial

Tieland, M., Dirks, M. L., van der Zwaluw, N., Verdijk, L. B., van de Rest, O., de Groot, L. C. P. G. M., & van Loon, L. J. C. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.05.020 · Cited by 556 · see citing works

The effect of protein supplements on functional frailty in older persons: A systematic review and meta-analysis

Oktaviana, J., Zanker, J., Vogrin, S., & Duque, G. (2019) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2019.103938 · Cited by 46 · see citing works