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Cited by 5,843

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Updating and Validating the Charlson Comorbidity Index and Score for Risk Adjustment in Hospital Discharge Abstracts Using Data From 6 Countries

Quan, H., Li, B., Couris, C. M., Fushimi, K., Graham, P., Hider, P., Januel, J.-M., Sundararajan, V.·2011·American Journal of Epidemiology
DOI 10.1093/aje/kwq433
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Abstract

With advances in the effectiveness of treatment and disease management, the contribution of chronic comorbid diseases (comorbidities) found within the Charlson comorbidity index to mortality is likely to have changed since development of the index in 1984. The authors reevaluated the Charlson index and reassigned weights to each condition by identifying and following patients to observe mortality within 1 year after hospital discharge. They applied the updated index and weights to hospital discharge data from 6 countries and tested for their ability to predict in-hospital mortality. Compared with the original Charlson weights, weights generated from the Calgary, Alberta, Canada, data (2004) were 0 for 5 comorbidities, decreased for 3 comorbidities, increased for 4 comorbidities, and did not change for 5 comorbidities. The C statistics for discriminating in-hospital mortality between the new score generated from the 12 comorbidities and the Charlson score were 0.825 (new) and 0.808 (old), respectively, in Australian data (2008), 0.828 and 0.825 in Canadian data (2008), 0.878 and 0.882 in French data (2004), 0.727 and 0.723 in Japanese data (2008), 0.831 and 0.836 in New Zealand data (2008), and 0.869 and 0.876 in Swiss data (2008). The updated index of 12 comorbidities showed good-to-excellent discrimination in predicting in-hospital mortality in data from 6 countries and may be more appropriate for use with more recent administrative data.

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Metadata

Authors
Quan, H., Li, B., Couris, C. M., Fushimi, K., Graham, P., Hider, P., Januel, J.-M., & Sundararajan, V.
Venue
American Journal of Epidemiology
Publisher
Oxford University Press (OUP)
Published
2011-02-17
Volume
173
Issue
6
Pages
676-682
ISSN
  • 0002-9262 (ISSN-L)
  • 1476-6256
DOI
10.1093/aje/kwq433
OpenAlex
W2121656227
Cited by
5,843
References
7
FWCI
35.01
Type
journal article
Language
en
Open access
closed

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