CoChat
Sign Up
Cited by 173Blood Pressure and Hypertension StudiesSodium Intake and HealthNutritional Studies and Diet

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

Effect of Dietary Pulses on Blood Pressure: A Systematic Review and Meta-analysis of Controlled Feeding Trials

Open access
Jayalath, V. H., de Souza, R. J., Sievenpiper, J. L., Ha, V., Chiavaroli, L., Mirrahimi, A., Di Buono, M., Bernstein, A. M., Leiter, L. A., Kris-Etherton, P. M., Vuksan, V., Beyene, J., Kendall, C. W. C., Jenkins, D. J. A.·2014·American Journal of Hypertension
DOI 10.1093/ajh/hpt155PMC PMC5391775
Open this paper in CoChat — free accountOpen PDF

Abstract

BACKGROUND: Current guidelines recommend diet and lifestyle modifications for primary prevention and treatment of hypertension, but do not encourage dietary pulses specifically for lowering blood pressure (BP). To quantify the effect of dietary pulse interventions on BP and provide evidence for their inclusion in dietary guidelines, a systematic review and meta-analysis of controlled feeding trials was conducted. METHODS: MEDLINE, EMBASE, Cochrane Library, and CINAHL were each searched from inception through 5 May 2013. Human trials ≥3 weeks that reported data for systolic, diastolic, and/or mean arterial BPs were included. Two reviewers independently extracted data and assessed methodological quality and risk of bias of included studies. Effect estimates were pooled using random effects models, and reported as mean differences (MD) with 95% confidence intervals (CIs). Heterogeneity was assessed (χ(2) test) and quantified (I(2)). RESULTS: Eight isocaloric trials (n = 554 participants with and without hypertension) were included in the analysis. Dietary pulses, exchanged isocalorically for other foods, significantly lowered systolic (MD = -2.25 mm Hg (95% CI, -4.22 to -0.28), P = 0.03) and mean arterial BP (MD = -0.75 mm Hg (95% CI, -1.44 to -0.06), P = 0.03), and diastolic BP non-significantly (MD = -0.71 mm Hg (95% CI, -1.74 to 0.31), P = 0.17). Heterogeneity was significant for all outcomes. CONCLUSIONS: Dietary pulses significantly lowered BP in people with and without hypertension. Higher-quality large-scale trials are needed to support these findings. CLINICAL TRIAL REGISTRATION: NCT01594567.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/ajh/hpt155

Cites

50 of 50 references verified0 citation errors · 0 not checkable

Statistics

Figures

Figure 1. Flow diagram of the literature search. The search identified 341 reports, 326 of which were determined to be irrelevant based on review of titles and abstracts. The remaining 15 reports were reviewed in full. Eight reports providing data for 8 trials of isocaloric comparisons were included in the analysis.
Figure 1. Flow diagram of the literature search. The search identified 341 reports, 326 of which were determined to be irrelevant based on review of titles and abstracts. The remaining 15 reports were reviewed in full. Eight reports providing data for 8 trials of isocaloric comparisons were included in the analysis.CC BY-NC · PubMed Central
Figure 2. Forest plot of clinical trials investigating the effect of isocaloric exchange of dietary pulses for other adequate comparators on systolic blood pressure (SBP; 2.1), diastolic blood pressure (DBP; 2.2), and mean arterial pressure (MAP; 2.3). The pooled effect estimate is represented as a diamond. Data are represented as mean differences (MDs) with 95% confidence intervals (CIs). P values are for generic inverse variance random effects models. Interstudy heterogeneity was assessed via Cochrane Q (χ2) at a significance level of P <0.10 and quantified by I2, where I2 >50% was considered to be evidence of substantial heterogeneity.
Figure 2. Forest plot of clinical trials investigating the effect of isocaloric exchange of dietary pulses for other adequate comparators on systolic blood pressure (SBP; 2.1), diastolic blood pressure (DBP; 2.2), and mean arterial pressure (MAP; 2.3). The pooled effect estimate is represented as a diamond. Data are represented as mean differences (MDs) with 95% confidence intervals (CIs). P values are for generic inverse variance random effects models. Interstudy heterogeneity was assessed via Cochrane Q (χ2) at a significance level of P <0.10 and quantified by I2, where I2 >50% was considered to be evidence of substantial heterogeneity.CC BY-NC · PubMed Central

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 50 references

Research works printed but not linked: 1

  1. Diao, 2012, Cochrane database of systematic reviews (Online), 8, CD006742

Cited by

Sorted by citations

Related

See all

Metadata

Authors
Jayalath, V. H., de Souza, R. J., Sievenpiper, J. L., Ha, V., Chiavaroli, L., Mirrahimi, A., Di Buono, M., Bernstein, A. M., Leiter, L. A., Kris-Etherton, P. M., Vuksan, V., Beyene, J., Kendall, C. W. C., & Jenkins, D. J. A.
Affiliations
  • St. Michael's Hospital (CA)
  • Cleveland Clinic (US)
  • McMaster University (CA)
ORCID
Venue
American Journal of Hypertension
Publisher
Oxford University Press (OUP)
Published
2013-09-07
Volume
27
Issue
1
Pages
56-64
ISSN
  • 0895-7061 (ISSN-L)
  • 1941-7225
DOI
10.1093/ajh/hpt155
PMC
PMC5391775
OpenAlex
W2107126748
Cited by
173
References
50
Citations by year
2026: 4 · 2025: 8 · 2024: 18 · 2023: 10 · 2022: 17 · 2021: 10 · 2020: 24 · 2019: 21 · 2018: 14 · 2017: 13 · 2016: 14 · 2015: 9 · 2014: 10 · 2013: 1
FWCI
1.94
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • American Journal of Hypertension (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Funders
  • American Heart Association
  • Abbott Laboratories
  • Coca-Cola Foundation
  • Canadian Nutrition Society
  • Government of Canada
  • European Association for the Study of Diabetes
  • National Institutes of Health
  • Canadian Institutes of Health Research
  • Natural Sciences and Engineering Research Council of Canada
  • National Institute of Diabetes and Digestive and Kidney Diseases
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords
Fabaceae, blood pressure, hypertension, systolic blood pressure, diastolic blood pressure, mean arterial pressure, isocaloric substitution, dietary guidelines, plant-based diet
MeSH terms
Blood Pressure, Diet, Humans, Hypertension, Fabaceae, Primary Prevention, Risk Factors, Seeds, Time Factors, Chi-Square Distribution, Treatment Outcome, Risk Reduction Behavior

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review