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Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities

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A high-resolution mRNA expression time course of embryonic development in zebrafish

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Bypassing Negative Epistasis on Yield in Tomato Imposed by a Domestication Gene

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Trisomy 21 consistently activates the interferon response

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Comprehensive Analysis of the Transcriptional and Mutational Landscape of Follicular and Papillary Thyroid Cancers

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Tximeta: Reference sequence checksums for provenance identification in RNA-seq

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Developmental dynamics of lncRNAs across mammalian organs and species

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Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression

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IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity

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The long noncoding RNA Wisper controls cardiac fibrosis and remodeling

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Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization

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Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis.

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hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing

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Transcriptional regulation of nitrogen-associated metabolism and growth

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Beyond bulk: a review of single cell transcriptomics methodologies and applications

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Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression

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METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation

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Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4+ and PDPN+ CAFs to clinical outcome

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An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function

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Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice

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IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria

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Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes

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The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment

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Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease

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Human naive epiblast cells possess unrestricted lineage potential

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Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma

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Genome Editing in Primary Cells and in Vivo Using Viral-Derived Nanoblades Loaded with Cas9-SgRNA Ribonucleoproteins

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A genomic and epigenomic atlas of prostate cancer in Asian populations

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Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma

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Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma

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Wnt addiction of genetically defined cancers reversed by PORCN inhibition

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The BRAF Pseudogene Functions as a Competitive Endogenous RNA and Induces Lymphoma In Vivo

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Mesenchymal inflammation drives genotoxic stress in hematopoietic stem cells and predicts disease evolution in human pre-leukemia

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Bifidobacterium adolescentis as a key member of the human gut microbiota in the production of GABA

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Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets

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Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells

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A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

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Cannabis glandular trichomes alter morphology and metabolite content during flower maturation

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Verrucomicrobia use hundreds of enzymes to digest the algal polysaccharide fucoidan

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Comparative metagenomic and metatranscriptomic analyses reveal the breed effect on the rumen microbiome and its associations with feed efficiency in beef cattle

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Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity

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Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis

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Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation

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Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles

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An intercross population study reveals genes associated with body size and plumage color in ducks

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OncodriveFML: a general framework to identify coding and non-coding regions with cancer driver mutations

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Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

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Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability

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Early embryonic-like cells are induced by downregulating replication-dependent chromatin assembly

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Modeling of TREX1-dependent autoimmune disease using human stem cells highlights L1 accumulation as a source of neuroinflammation

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Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes

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Spatial Gene-Expression Gradients Underlie Prominent Heterogeneity of CA1 Pyramidal Neurons

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The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration

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Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue

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Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases

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Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis

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LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse

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A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans

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The mitochondrial respiratory chain is essential for haematopoietic stem cell function

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