Cited by 246Neurobiology of Language and BilingualismNeuroscience and Music PerceptionPhonetics and Phonology Research

Defining a left-lateralized response specific to intelligible speech using fMRI

Narain, C.·2003·Cerebral Cortex

Abstract

Functional imaging studies of language have shown bilateral superior temporal activations in response to 'passive' perception of speech when the baseline condition did not control for the acoustic complexity of speech. Controlling for this complexity demonstrates speech-specific processing lateralized to the left temporal lobe, and our recent positron emission tomography study has emphasized a role for left anterolateral temporal cortex in speech comprehension. This contrasts with the more usual view that relates speech comprehension to left temporal-parietal cortex, the ill-defined area of Wernicke. This study attempted to reconcile these differences, using a more sensitive 3 T functional magnetic resonance imaging system, and a sparse sampling paradigm. We found left lateralized activations for intelligible speech with two distinct foci, one in the anterior superior temporal sulcus and the other on the posterior temporal lobe. Therefore, the results demonstrate that there are neural responses to intelligible speech along the length of the left lateral temporal neocortex, although the precise processing roles of the anterior and posterior regions cannot be determined from this study.

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Crossref · 10.1093/cercor/bhg083

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  • The speech selective auditory response in the left posterior superior temporal sulcus was repeatedly demonstrated even when acoustic complexity was controlled.

    “The speech selective auditory response in the left posterior superior temporal sulcus was repeatedly demonstrated even when acoustic complexity was controlled (Narain et al., 2003; Giraud et al., 2004; Hugdahl et al., 2003; Benson et al., 2006; Rimol et al., 2006).”

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Authors
Narain, C.
Affiliations
John Radcliffe Hospital (GB)
Corresponding author
Narain, C.
Venue
Cerebral Cortex
Published
2003-12-01
Volume
13
Issue
12
Pages
1362-1368
ISSN
  • 1047-3211 (ISSN-L)
  • 1460-2199
OpenAlex
W2118593493
Cited by
246
References
43
Citations by year
2026: 1 · 2025: 6 · 2024: 8 · 2023: 7 · 2022: 5 · 2021: 11 · 2020: 6 · 2019: 8 · 2018: 7 · 2017: 14 · 2016: 3 · 2015: 13 · 2014: 6 · 2013: 18 · 2012: 22
FWCI
6.51
Type
journal article
Language
en
Open access
closed
Locations
  • Cerebral Cortex (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Funders
Wellcome Trust (090961)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Phonetics and Phonology Research
Keywords
speech understanding, left lateralization, left temporal lobe, posterior temporal lobe, intelligible speech, acoustic complexity, Wernicke's area, auditory cortex
MeSH terms
Acoustic Stimulation, Adult, Brain Mapping, Dominance, Cerebral, Female, Humans, Language, Magnetic Resonance Imaging, Male, Neurons, Speech Intelligibility, Speech Perception, Temporal Lobe

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