Cited by 76Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene RegulationNuclear Receptors and Signaling

Comparative Aspects of Subplate Zone Studied with Gene Expression in Sauropsids and Mammals

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Wang, Wei Zhi, Oeschger, Franziska M., Montiel, Juan F., García-Moreno, Fernando, Hoerder-Suabedissen, Anna, Krubitzer, Leah, Ek, Carl Joakim, Saunders, Norman R. +3 more·2011·Cerebral Cortex

Abstract

There is currently a debate about the evolutionary origin of the earliest generated cortical preplate neurons and their derivatives (subplate and marginal zone). We examined the subplate with murine markers including nuclear receptor related 1 (Nurr1), monooxygenase Dbh-like 1 (Moxd1), transmembrane protein 163 (Tmem163), and connective tissue growth factor (Ctgf) in developing and adult turtle, chick, opossum, mouse, and rat. Whereas some of these are expressed in dorsal pallium in all species studied (Nurr1, Ctgf, and Tmem163), we observed that the closely related mouse and rat differed in the expression patterns of several others (Dopa decarboxylase, Moxd1, and thyrotropin-releasing hormone). The expression of Ctgf, Moxd1, and Nurr1 in the oppossum suggests a more dispersed subplate population in this marsupial compared with mice and rats. In embryonic and adult chick brains, our selected subplate markers are primarily expressed in the hyperpallium and in the turtle in the main cell dense layer of the dorsal cortex. These observations suggest that some neurons that express these selected markers were present in the common ancestor of sauropsids and mammals.

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Crossref · 10.1093/cercor/bhq278

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  • In mouse and other species, SP is molecularly distinct.

    “In mouse and other species18 this layer is molecularly distinct, and our laminar profiling also identified many SP-enriched genes in human (Fig. 2).”

    From Transcriptional landscape of the prenatal human brain (2014) · cites this paper as [18]

  • Many genes showed similar enrichment in developing mouse and human SP, including KCNAB1 and NR4A2.

    “Many genes showed similar enrichment in the developing mouse and human SP, including the known SP markers KCNAB1 and NR4A217,18,44 (Fig. 4b).”

    From Transcriptional landscape of the prenatal human brain (2014) · cites this paper as [18]

  • Trh is also not expressed in rat SP, suggesting this pattern is specific to mouse.

    “Interestingly, Trh is also not expressed in the rat SP18, suggesting this pattern is specific to mouse.”

    From Transcriptional landscape of the prenatal human brain (2014) · cites this paper as [18]

  • Species differences in distinct fetal transient zones, including SZ, SP, CP, and SG, have been described.

    “Species differences in distinct fetal transient zones, including the SZ2, SP17,18, CP6, and SG9, have also been described.”

    From Transcriptional landscape of the prenatal human brain (2014) · cites this paper as [18]

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Authors
Wang, W. Z., Oeschger, F. M., Montiel, J. F., García-Moreno, F., Hoerder-Suabedissen, A., Krubitzer, L., Ek, C. J., Saunders, N. R., Reim, K., Villalón, A., & Molnár, Z.
Affiliations
  • University of Oxford (GB)
  • University of California, Davis (US)
  • The University of Melbourne (AU)
  • Max Planck Institute of Experimental Medicine (DE)
  • Universidad Diego Portales (CL)
Venue
Cerebral Cortex
Published
2011-03-02
Volume
21
Issue
10
Pages
2187-2203
ISSN
  • 1047-3211 (ISSN-L)
  • 1460-2199
OpenAlex
W2140846760
Cited by
76
References
118
Citations by year
2026: 1 · 2025: 4 · 2024: 6 · 2023: 3 · 2022: 3 · 2021: 2 · 2020: 7 · 2019: 5 · 2018: 8 · 2017: 5 · 2016: 5 · 2015: 7 · 2014: 4 · 2013: 4 · 2012: 5
FWCI
2.10
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Cerebral Cortex (publishedVersion)
  • PubMed (publishedVersion)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
  • Americanae (AECID Library) (submittedVersion, other-oa)
  • Max Planck Institute for Plasma Physics (submittedVersion)
  • MPG.PuRe (Max Planck Society) (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nuclear Receptors and Signaling
Keywords
subplate, marginal zone, cortical development, gene expression, Nurr1, connective tissue growth factor, aromatic L-amino acid decarboxylase, thyrotropin-releasing hormone, sauropsids, marsupials, Didelphidae, turtles, chicks, mice, rats, dorsal pallium, comparative neuroanatomy
MeSH terms
Age Factors, Animals, Animals, Newborn, Cerebral Cortex, Chick Embryo, Humans, Mice, Inbred C57BL, Opossums, Species Specificity, Turtles, Rats, Wistar, Gene Expression Regulation, Developmental, Evolution, Molecular, Mice, Rats

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