G1 Phase Regulation, Area-Specific Cell Cycle Control, and Cytoarchitectonics in the Primate Cortex
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We have investigated the cell cycle-related mechanisms that lead to the emergence of primate areas 17 and 18. These areas are characterized by striking differences in cytoarchitectonics and neuron number. We show in vivo that (1) area 17 precursors of supragranular neurons exhibit a shorter cell cycle duration, a reduced G1 phase, and a higher rate of cell cycle reentry than area 18 precursors; (2) area 17 and area 18 precursors show contrasting and specific levels of expression of cyclin E (high in area 17, low in area 18) and p27Kip1 (low in area 17, high in area 18); (3) ex vivo up- and downmodulation of cyclin E and p27Kip1 show that both regulators influence cell cycle kinetics by modifying rates of cell cycle progression and cell cycle reentry; (4) modeling the areal differences in cell cycle parameters suggests that they contribute to areal differences in numbers of precursors and neuron production.
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oRGs are present in large numbers in gyrencephalic primates and are considered pivotal to the evolutionary increase in human cortex size and complexity.
“oRGs are present in large numbers in gyrencephalic primates22,23,40–44 and are considered pivotal to the evolutionary increase in human cortex size and complexity45,46.”
From The use of brain organoids to investigate neural development and disease (2017) · cites this paper as [41]
Cites
R: A Language and Environment for Statistical Computing
R Core Team (2000) · doi:10.32614/r.manuals · Cited by 355,706 · see citing works
(2005) · Springer eBooks · doi:10.1007/0-387-27255-0_9 · Cited by 20,333 · see citing works
CDK inhibitors: positive and negative regulators of G1-phase progression
Sherr, C. J., & Roberts, J. M. (1999) · Genes & Development · doi:10.1101/gad.13.12.1501 · Cited by 6,115 · see citing works
Specification of Cerebral Cortical Areas
Rakic, P. (1988) · Science · doi:10.1126/science.3291116 · Cited by 3,127 · see citing works
Christensen, R. (1990) · Springer texts in statistics · doi:10.1007/978-1-4757-4111-7_10 · Cited by 2,941 · see citing works
Schuenemeyer, J. H., McCullagh, P. J., & Nelder, J. A. (1992) · Technometrics · doi:10.2307/1269238 · Cited by 2,702 · see citing works
Noctor, S. C., Martínez-Cerdeño, V., Ivic, L., & Kriegstein, A. R. (2004) · Nature Neuroscience · doi:10.1038/nn1172 · Cited by 2,229 · see citing works
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21.
Toyoshima, H., & Hunter, T. (1994) · Cell · doi:10.1016/0092-8674(94)90573-8 · Cited by 2,208 · see citing works
Neurons derived from radial glial cells establish radial units in neocortex
Noctor, S. C., Flint, A. C., Weissman, T. A., Dammerman, R. S., & Kriegstein, A. R. (2001) · Nature · doi:10.1038/35055553 · Cited by 2,016 · see citing works
Polyak, K., Kato, J., Solomon, M., Sherr, C., Massagué, J., Roberts, J., & Koff, A. (1994) · Genes & Development · doi:10.1101/gad.8.1.9 · Cited by 1,949 · see citing works
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3.Preprint
Niwa, H., Burdon, T., Chambers, I., & Smith, A. G. (1998) · Genes & Development · doi:10.1101/gad.12.13.2048 · Cited by 1,673 · see citing works
Cell population kinetics in the intestinal epithelium of the mouse
Quastler, H., & Sherman, F. G. (1959) · Experimental Cell Research · doi:10.1016/0014-4827(59)90063-1 · Cited by 1,432 · see citing works
Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27
Kiyokawa, H., Kineman, R. D., Manova-Todorova, K. O., Soares, V., Hoffman, E. S., Ono, M., Khanam, D., Hayday, A., Frohman, L. A., & Koff, A. (1996) · Cell · doi:10.1016/s0092-8674(00)81238-6 · Cited by 1,243 · see citing works
Rakic, P. (1974) · Science · doi:10.1126/science.183.4123.425 · Cited by 1,161 · see citing works
Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage
Malatesta, P., Hartfuss, E., & Götz, M. (2000) · Development · doi:10.1242/dev.127.24.5253 · Cited by 1,157 · see citing works
Rakic, P. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)93934-p · Cited by 1,047 · see citing works
Haubensak, W. E., Attardo, A., Denk, W. T., & Huttner, W. Β. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308600100 · Cited by 1,004 · see citing works
Resnitzky, D., Gossen, M., Bujard, H., & Reed, S. I. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.3.1669-1679.1994 · Cited by 965 · see citing works
Kostović, I., & RAKIC, P. T. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902970309 · Cited by 912 · see citing works
THE BASIC UNIFORMITY IN STRUCTURE OF THE NEOCORTEX
Röckel, A., Hiorns, R. W., & Powell, T. P. S. (1980) · Brain · doi:10.1093/brain/103.2.221 · Cited by 902 · see citing works
Association of human cyclin E with a periodic G1-S phase protein kinase
Dulić, V., Lees, E. M., & Reed, S. I. (1992) · Science · doi:10.1126/science.1329201 · Cited by 882 · see citing works
Nowakowski, R. S., Lewin, S. B., & Miller, M. W. (1989) · Journal of Neurocytology · doi:10.1007/bf01190834 · Cited by 755 · see citing works
Origin of GABAergic neurons in the human neocortex
Letinić, K., Zoncu, R., & RAKIC, P. T. (2002) · Nature · doi:10.1038/nature00779 · Cited by 718 · see citing works
Cell Cycle Dependence of Laminar Determination in Developing Neocortex
McConnell, S. K., & Kaznowski, C. E. (1991) · Science · doi:10.1126/science.1925583 · Cited by 712 · see citing works
Smart, I. H. M. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.1.37 · Cited by 687 · see citing works
The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall
Takahashi, T., Nowakowski, R. S., & Caviness, V. S. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-09-06046.1995 · Cited by 673 · see citing works
Resnitzky, D., Gossen, M., Bujard, H., & Reed, S. I. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.3.1669 · Cited by 664 · see citing works
Nieto, M., Monuki, E. S., Tang, H., Imitola, J., Haubst, N., Khoury, S. J., Cunningham, J., Götz, M., & Walsh, C. A. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20322 · Cited by 548 · see citing works
Kioussi, C., Briata, P., Baek, S. H., Rose, D. W., Hamblet, N. S., Herman, T., Ohgi, K. A., Lin, C. R., Gleiberman, A. S., Wang, J., et al. (2002) · Cell · doi:10.1016/s0092-8674(02)01084-x · Cited by 543 · see citing works
G Protein-Coupled Receptor-Dependent Development of Human Frontal Cortex
Piao, X., Hill, R. S., Bodell, A., Chang, B. S., Basel-Vanagaite, L., Straussberg, R., Dobyns, W. B., Qasrawi, B., Winter, R. M., Innes, A. M., et al. (2004) · Science · doi:10.1126/science.1092780 · Cited by 517 · see citing works
Pathways governing G1/S transition and their response to DNA damage
Bartek, J. J., & Lukas, J. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02114-7 · Cited by 467 · see citing works
Development and plasticity of cortical areas and networks
Sur, M., & Leamey, C. A. (2001) · Nature reviews. Neuroscience · doi:10.1038/35067562 · Cited by 372 · see citing works
Oliver, T. G., Grasfeder, L. L., Carroll, A. L., Kaiser, C., Gillingham, C. L., Lin, S. M., Wickramasinghe, R. S., Scott, M. P., & Wechsler‐Reya, R. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0832317100 · Cited by 364 · see citing works
Cell cycle dependence of laminar determination in developing neocortex
McConnell, S., & Kaznowski, C. E. (1991) · Science · doi:10.1126/science.254.5029.282 · Cited by 353 · see citing works
What is the restriction point?
Zetterberg, A., Larsson, O., & Wiman, K. G. (1995) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(95)80067-0 · Cited by 351 · see citing works
Cortical upper layer neurons derive from the subventricular zone as indicated bySvet1gene expression
Tarabykin, V. S., Stoykova, A., Usman, N. Y., & Gruß, P. (2001) · Development · doi:10.1242/dev.128.11.1983 · Cited by 326 · see citing works
Durand, B., Gao, F., & RAFF, M. C. (1997) · The EMBO Journal · doi:10.1093/emboj/16.2.306 · Cited by 324 · see citing works
Changes in cell-cycle kinetics during the development and evolution of primate neocortex
Kornack, D. R., & RAKIC, P. T. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.3.1242 · Cited by 288 · see citing works
O’Leary, D. D. M., & Nakagawa, Y. (2002) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(02)00285-4 · Cited by 277 · see citing works
Kostovic, I., & Rakic, P. (1984) · The Journal of Neuroscience · doi:10.1523/jneurosci.04-01-00025.1984 · Cited by 270 · see citing works
Neurogenesis and the Cell Cycle
Ohnuma, S., & Harris, W. A. (2003) · Neuron · doi:10.1016/s0896-6273(03)00632-9 · Cited by 259 · see citing works
G ENERATING THE C EREBRAL C ORTICAL A REA M AP
Grove, E. A., & Shimogori, T. (2003) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131137 · Cited by 254 · see citing works
Zimmer, C. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh102 · Cited by 240 · see citing works
Regulation of the Cell Cycle at the G1–S Transition by Proteolysis of Cyclin E and p27Kip1
Nakayama, K., Hatakeyama, S., & Nakayama, K. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.4627 · Cited by 239 · see citing works
Genetic Control of Cortical Regionalization and Connectivity
Rubenstein, J. L. R. (1999) · Cerebral Cortex · doi:10.1093/cercor/9.6.524 · Cited by 224 · see citing works
Embryonic and Early Fetal Development of the Human Neocortex
Meyer, G., Schaaps, J. P., Moreau, L., & Goffinet, A. M. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-05-01858.2000 · Cited by 215 · see citing works
Caviness, V. S. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.6.592 · Cited by 188 · see citing works
Craig, C., Wersto, R. P., Kim, M., et al. (1997) · Oncogene · doi:10.1038/sj.onc.1201064 · Cited by 186 · see citing works
Cell-Cycle Kinetics of Neocortical Precursors Are Influenced by Embryonic Thalamic Axons
Dehay, C., Savatier, P., Cortay, V., & Kennedy, H. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-01-00201.2001 · Cited by 180 · see citing works
Self-citationRAKIC, P. T. (1973) · The Journal of Comparative Neurology · doi:10.1002/cne.901470407 · Cited by 173 · see citing works
Zindy, F., Cunningham, J. J., Sherr, C. J., Jogal, S., Smeyne, R. J., & Roussel, M. F. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13462 · Cited by 172 · see citing works
Modulation of the cell cycle contributes to the parcellation of the primate visual cortex
Dehay, C., Giroud, P., Berland, M., Smart, I. H. M., & Kennedy, H. (1993) · Nature · doi:10.1038/366464a0 · Cited by 156 · see citing works
Self-citationRegulated subset of G 1 growth-control genes in response to derepression by the Wnt pathway
Baek, S. H., Kioussi, C., Briata, P., Wang, D., Nguyen, H., Ohgi, K. A., Glass, C. K., Wynshaw-Boris, A. J., Rose, D. W., & Rosenfeld, M. G. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0330217100 · Cited by 148 · see citing works
Lukaszewicz, A. I., Savatier, P., Cortay, V., Kennedy, H., & Dehay, C. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06610.2002 · Cited by 148 · see citing works
Self-citationMechanisms of cerebral cortical patterning in mice and humans
Monuki, E. S., & Walsh, C. A. (2001) · Nature Neuroscience · doi:10.1038/nn752 · Cited by 145 · see citing works
Cell cycle and cell fate in the nervous system
Ohnuma, S., Philpott, A., & Harris, W. A. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00175-6 · Cited by 127 · see citing works
Wimmel, A., Lucibello, F. C., Sewing, A., Adolph, S., & Müller, R. (1994) · PubMed · Cited by 126 · see citing works
Golgi and Nissl studies of the visual cortex of the bottlenose dolphin
Garey, L. J., Winkelmann, E., & Brauer, K. (1985) · The Journal of Comparative Neurology · doi:10.1002/cne.902400307 · Cited by 114 · see citing works
Expression of INK4 inhibitors of cyclin D-dependent kinases during mouse brain development.
Zindy, F., Soares, H. D., Herzog, K., Morgan, J., Sherr, C. J., & Roussel, M. F. (1997) · PubMed · Cited by 114 · see citing works
Genetic Control of Cortical Convolutions
RAKIC, P. T. (2004) · Science · doi:10.1126/science.1096414 · Cited by 111 · see citing works
Cortical Specification of Mice and Men
Kennedy, H., & Dehay, C. (1993) · Cerebral Cortex · doi:10.1093/cercor/3.3.171 · Cited by 109 · see citing works
Self-citationSmart, I. H. M., & McSherry, G. M. (1982) · PubMed · Cited by 105 · see citing works
Accumulation of Cyclin E Is Not a Prerequisite for Passage through the Restriction Point
Ekholm, S. V., Zickert, P., Reed, S. I., & Zetterberg, A. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.9.3256-3265.2001 · Cited by 99 · see citing works
Mitsuhashi, T., Aoki, Y., Ekşioğlu, Y. Z., Takahashi, T., Bhide, P. G., Reeves, S. A., & Caviness, V. S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111051398 · Cited by 97 · see citing works
Polleux, F., Dehay, C., Moraillon, B., & Kennedy, H. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-20-07763.1997 · Cited by 95 · see citing works
Self-citationŠestan, N., RAKIC, P. T., & Donoghue, M. J. (2001) · Current Biology · doi:10.1016/s0960-9822(00)00043-9 · Cited by 86 · see citing works
Mummery, C. L., van den Brink, C. E., & de Laat, S. W. (1987) · Developmental Biology · doi:10.1016/0012-1606(87)90133-3 · Cited by 78 · see citing works
Tokumoto, Y. M., Apperly, J. A., Gao, F., & RAFF, M. C. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0626 · Cited by 72 · see citing works
Beaulieu, C., & Colonnier, M. (1989) · The Journal of Comparative Neurology · doi:10.1002/cne.902790206 · Cited by 69 · see citing works
Heterogeneity in the columnar number of neurons in different neocortical areas in the rat
Skoglund, T. S., Pascher, R., & Berthold, C. ‐. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(96)12569-6 · Cited by 56 · see citing works
Polleux, F. (2001) · Cerebral Cortex · doi:10.1093/cercor/11.11.1027 · Cited by 52 · see citing works
Lipofection strategy for the study of Xenopus retinal development
Ohnuma, S., Mann, F., Boy, S., Perron, M., & Harris, W. A. (2002) · Methods · doi:10.1016/s1046-2023(02)00260-8 · Cited by 43 · see citing works
Constructing the mammalian neocortex: the role of intrinsic factors
Job, C., & Tan, S. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00070-8 · Cited by 33 · see citing works
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Development and Evolution of the Human Neocortex
Lui, J. H., Hansen, D. V., & Kriegstein, A. R. (2011) · Cell · doi:10.1016/j.cell.2011.06.030 · Cited by 1,342 · see citing works
Neurogenic radial glia in the outer subventricular zone of human neocortex
Hansen, D. V., Lui, J. H., Parker, P. R. L., & Kriegstein, A. R. (2010) · Nature · doi:10.1038/nature08845 · Cited by 1,388 · see citing works
An RNA gene expressed during cortical development evolved rapidly in humans
Pollard, K. S., Salama, S. R., Lambert, N., Lambot, M.-A., Coppens, S., Pedersen, J. S., Katzman, S., King, B., Onodera, C., Siepel, A., et al. (2006) · Nature · doi:10.1038/nature05113 · Cited by 1,005 · see citing works
Self-citationMolecular logic of neocortical projection neuron specification, development and diversity
Greig, L. C., Woodworth, M. B., Galazo, M. J., Padmanabhan, H., & Macklis, J. D. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3586 · Cited by 863 · see citing works
OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling
Fietz, S. A., Kelava, I., Vogt, J., Wilsch-Bräuninger, M., Stenzel, D., Fish, J. L., Corbeil, D., Riehn, A., Distler, W., Nitsch, R., et al. (2010) · Nature Neuroscience · doi:10.1038/nn.2553 · Cited by 830 · see citing works
Anatomy of hierarchy: Feedforward and feedback pathways in macaque visual cortex
Markov, N. T., Vezoli, J., Chameau, P., Falchier, A., Quilodran, R., Huissoud, C., Lamy, C., Misery, P., Giroud, P., Ullman, S., et al. (2014) · Journal of Comparative Neurology · doi:10.1002/cne.23458 · Cited by 759 · see citing works
Self-citationThe use of brain organoids to investigate neural development and disease
Di Lullo, E., & Kriegstein, A. R. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.107 · Cited by 788 · see citing works
Cell-cycle control and cortical development
Dehay, C., & Kennedy, H. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2097 · Cited by 655 · see citing works
Self-citationHuman-specific gene <i>ARHGAP11B</i> promotes basal progenitor amplification and neocortex expansion
Florio, M., Albert, M., Taverna, E., Namba, T., Brandl, H., Lewitus, E., Haffner, C., Sykes, A., Wong, F. K., Peters, J., et al. (2015) · Science · doi:10.1126/science.aaa1975 · Cited by 632 · see citing works
Bershteyn, M., Nowakowski, T. J., Pollen, A. A., Di Lullo, E., Nene, A., Wynshaw-Boris, A., & Kriegstein, A. R. (2017) · Cell Stem Cell · doi:10.1016/j.stem.2016.12.007 · Cited by 566 · see citing works
Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells
Nowakowski, T. J., Pollen, A. A., Di Lullo, E., Sandoval-Espinosa, C., Bershteyn, M., & Kriegstein, A. R. (2016) · Cell Stem Cell · doi:10.1016/j.stem.2016.03.012 · Cited by 529 · see citing works
Molecular taxonomy of major neuronal classes in the adult mouse forebrain
Sugino, K., Hempel, C. M., Miller, M. N., Hattox, A. M., Shapiro, P., Wu, C., Huang, Z. J., & Nelson, S. B. (2006) · Nature Neuroscience · doi:10.1038/nn1618 · Cited by 521 · see citing works
Betizeau, M., Cortay, V., Patti, D., Pfister, S., Gautier, E., Bellemin-Ménard, A., Afanassieff, M., Huissoud, C., Douglas, R. J., Kennedy, H., et al. (2013) · Neuron · doi:10.1016/j.neuron.2013.09.032 · Cited by 462 · see citing works
Self-citationDevelopment and arealization of the cerebral cortex
Cadwell, C. R., Bhaduri, A., Mostajo-Radji, M. A., Keefe, M. G., & Nowakowski, T. J. (2019) · Neuron · doi:10.1016/j.neuron.2019.07.009 · Cited by 408 · see citing works
Role of Intermediate Progenitor Cells in Cerebral Cortex Development
Pontious, A., Kowalczyk, T., Englund, C., & Hevner, R. F. (2008) · Developmental Neuroscience · doi:10.1159/000109848 · Cited by 378 · see citing works
The outer subventricular zone and primate-specific cortical complexification
Dehay, C., Kennedy, H., & Kosik, K. S. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.060 · Cited by 314 · see citing works
Self-citationMaking bigger brains–the evolution of neural-progenitor-cell division
Fish, J. L., Dehay, C., Kennedy, H., & Huttner, W. B. (2008) · Journal of Cell Science · doi:10.1242/jcs.023465 · Cited by 274 · see citing works
Self-citationDeconstructing cortical folding: genetic, cellular and mechanical determinants
Llinares-Benadero, C., & Borrell, V. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0112-2 · Cited by 243 · see citing works
Cortical and Clonal Contribution of Tbr2 Expressing Progenitors in the Developing Mouse Brain
Vasistha, N. A., García-Moreno, F., Arora, S., Cheung, A. F. P., Arnold, S. J., Robertson, E. J., & Molnár, Z. (2015) · Cerebral Cortex · doi:10.1093/cercor/bhu125 · Cited by 177 · see citing works
“This has further been supported by artificial modification of cell-cycle parameters leading to changes in cortical numbers (Lukaszewicz et al. 2005; Pilaz et al. 2009) and also by genetic and transcriptomic studies (Bishop 2000; Pinto et al. 2009; Elsen et al. 2013).”
BackgroundMethodEmerging roles of neural stem cells in cerebral cortex development and evolution
Borrell, V., & Reillo, I. (2012) · Developmental Neurobiology · doi:10.1002/dneu.22013 · Cited by 185 · see citing works
Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor
Manuel, M. N., Mi, D., Mason, J. O., & Price, D. J. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00070 · Cited by 153 · see citing works
Yang, C., Przyborski, S., Cooke, M. J., Zhang, X., Stewart, R., Anyfantis, G., Atkinson, S. P., Saretzki, G., Armstrong, L., & Lako, M. (2008) · Stem Cells · doi:10.1634/stemcells.2007-0677 · Cited by 136 · see citing works
Scott, J. A., Habas, P. A., Kim, K., Rajagopalan, V., Hamzelou, K. S., Corbett‐Detig, J. M., Barkovich, A. J., Glenn, O. A., & Studholme, C. (2011) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2011.04.001 · Cited by 119 · see citing works
Is this a brain which I see before me? Modeling human neural development with pluripotent stem cells
Suzuki, I. K., & Vanderhaeghen, P. (2015) · Development · doi:10.1242/dev.120568 · Cited by 110 · see citing works
Thinking out of the dish: what to learn about cortical development using pluripotent stem cells
van den Ameele, J., Tiberi, L., Vanderhaeghen, P., & Espuny-Camacho, I. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2014.03.005 · Cited by 110 · see citing works
Gene networks controlling early cerebral cortex arealization
Mallamaci, A., & Stoykova, A. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04634.x · Cited by 95 · see citing works
Arcila, M. L., Betizeau, M., Cambronne, X. A., Guzman, E., Doerflinger, N., Bouhallier, F., Zhou, H., Wu, B., Rani, N., Bassett, D. S., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.01.017 · Cited by 80 · see citing works
Self-citationCellular and Molecular Mechanisms Linking Human Cortical Development and Evolution
Libé-Philippot, B., & Vanderhaeghen, P. (2021) · Annual Review of Genetics · doi:10.1146/annurev-genet-071719-020705 · Cited by 78 · see citing works
Comparative Aspects of Subplate Zone Studied with Gene Expression in Sauropsids and Mammals
Wang, W. Z., Oeschger, F. M., Montiel, J. F., García-Moreno, F., Hoerder-Suabedissen, A., Krubitzer, L., Ek, C. J., Saunders, N. R., Reim, K., Villalón, A., et al. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq278 · Cited by 76 · see citing works
Hypothesis on the Dual Origin of the Mammalian Subplate
Montiel, J. F., Wang, W. Z., Oeschger, F. M., Hoerder-Suabedissen, A., Tung, W. L., García-Moreno, F., Holm, I. E., Villalón, A., & Molnár, Z. (2011) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2011.00025 · Cited by 70 · see citing works
oRGs and mitotic somal translocation — a role in development and disease
Ostrem, B., Di Lullo, E., & Kriegstein, A. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2016.11.007 · Cited by 61 · see citing works
Gohlke, J. M., Griffith, W. C., & Faustman, E. M. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhl151 · Cited by 49 · see citing works
Cortical neurogenesis from pluripotent stem cells: complexity emerging from simplicity
Anderson, S., & Vanderhaeghen, P. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.03.012 · Cited by 40 · see citing works
Area Patterning of the Mammalian Cortex
O'Leary, D. D. M., Stocker, A. M., & Zembrzycki, A. (2013) · Patterning and Cell Type Specification in the Developing CNS and PNS · doi:10.1016/b978-0-12-397265-1.00021-6 · Cited by 14 · see citing works
- Authors
- Lukaszewicz, A., Savatier, P., Cortay, V., Giroud, P., Huissoud, C., Berland, M., Kennedy, H., & Dehay, C.
- Affiliations
- Lyon 1 Université (FR)
- Corresponding author
- Dehay, Colette
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2005-08
- Volume
- 47
- Issue
- 3
- Pages
- 353-364
- ISSN
- 0896-6273 (ISSN-L)
- PMC
- PMC1890568
- OpenAlex
- W2124843892
- Cited by
- 315
- References
- 73
- Citations by year
- 2026: 5 · 2025: 9 · 2024: 5 · 2023: 13 · 2022: 13 · 2021: 17 · 2020: 17 · 2019: 18 · 2018: 12 · 2017: 11 · 2016: 22 · 2015: 19 · 2014: 23 · 2013: 16 · 2012: 14
- FWCI
- 4.31
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- HAL (submittedVersion, other-oa)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Health Sciences › Medicine › Oncology › Cancer-related Molecular Pathways
- Keywords
- cell cycle re-entry, primate visual cortex, area 17, area 18, cyclin E, p27, neuronal precursors, neuron number, cell cycle kinetics, cortical development
- MeSH terms
- Animals, Cell Cycle, Cerebral Cortex, Fetus, Kinetics, Macaca fascicularis, Models, Neurological, Neurons, Time Factors, Down-Regulation, Up-Regulation, G1 Phase, Cell Cycle Proteins, Cyclin E, Tumor Suppressor Proteins, Fetal Development, Cyclin-Dependent Kinase Inhibitor p27, In Vitro Techniques
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