Conformation of the Bax C-terminus regulates subcellular location and cell death

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

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BAX activation is initiated at a novel interaction site

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Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

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Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module

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Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

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JNK promotes Bax translocation to mitochondria through phosphorylation of 14‐3‐3 proteins

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JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells

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Molecular biology of Bax and Bak activation and action

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Cathepsin D Triggers Bax Activation, Resulting in Selective Apoptosis-inducing Factor (AIF) Relocation in T Lymphocytes Entering the Early Commitment Phase to Apoptosis

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Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

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Bax assembles into large ring‐like structures remodeling the mitochondrial outer membrane in apoptosis

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Bax Exists in a Dynamic Equilibrium between the Cytosol and Mitochondria to Control Apoptotic Priming

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Structural Model of Active Bax at the Membrane

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Differential retrotranslocation of mitochondrial Bax and Bak

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Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function

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Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides

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Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax

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Crossing paths: interactions between the cell death machinery and growth factor survival signals

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Assembly of the Bak Apoptotic Pore

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Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin

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BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death

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Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization

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The Incomplete Puzzle of the BCL2 Proteins

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Regulation of Bax activation and apoptotic response to UV irradiation by p53 transcription-dependent and -independent pathways

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