Endometrial receptivity markers, the journey to successful embryo implantation.

Achache, Hanna; Revel, Ariel

doi:10.1093/humupd/dml004

Cited by 952Reproductive System and PregnancyReproductive Biology and FertilityEstrogen and related hormone effects

Endometrial receptivity markers, the journey to successful embryo implantation.

Achache, Hanna, Revel, Ariel·2006·Human Reproduction Update

DOI 10.1093/humupd/dml004

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Abstract

Human embryo implantation is a three-stage process (apposition, adhesion and invasion) involving synchronized crosstalk between a receptive endometrium and a functional blastocyst. This ovarian steroid-dependent phenomenon can only take place during the window of implantation, a self-limited period of endometrial receptivity spanning between days 20 and 24 of the menstrual cycle. Implantation involves a complex sequence of signalling events, consisting in the acquisition of adhesion ligands together with the loss of inhibitory components, which are crucial to the establishment of pregnancy. Histological evaluation, now considered to add little clinically significant information, should be replaced by functional assessment of endometrial receptivity. A large number of molecular mediators have been identified to date, including adhesion molecules, cytokines, growth factors, lipids and others. Thus, endometrial biopsy samples can be used to identify molecules associated with uterine receptivity to obtain a better insight into human implantation. In addition, development of functional in vitro systems to study embryo-uterine interactions will lead to better definition of the interactions existing between the molecules involved in this process. The purpose of this review was not only to describe the different players of the implantation process but also to try to portray the relationship between these factors and their timing in the process of uterine receptivity.

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Embryo implantation is a pivotal step during pregnancy, and failure of the embryo to implant into the uterine endometrium at early pregnancy stages is a major cause of infertility.
“Embryo implantation is a pivotal step during pregnancy and the failure of the embryo to implant into the uterine endometrium at early pregnancy stages is a major cause of infertility [45].”
From Estradiol and Progesterone Regulate the Migration of Mast Cells from the Periphery to the Uterus and Induce Their Maturation and Degranulation (2010) · cites this paper as [45]

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Untitled work
Hynes (2002) · doi:10.1016/s0092-8674(02)00971-6 · Cited by 8,606 · see citing works
The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression
Cano, A., Pérez‐Moreno, M., Rodrigo, I., Locascio, A., Blanco, M. J., Barrio, M. G. D., Portillo, F., & Nieto, M. A. (2000) · Nature Cell Biology · doi:10.1038/35000025 · Cited by 3,672 · see citing works
Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis
Gumbiner, B. M. (1996) · Cell · doi:10.1016/s0092-8674(00)81279-9 · Cited by 3,471 · see citing works
Dating the Endometrial Biopsy
Rw, N., Hertig, A. T., & Rock, J. A. (1950) · Fertility and Sterility · doi:10.1016/s0015-0282(16)30062-0 · Cited by 2,854 · see citing works
CYCLOOXYGENASES 1 AND 2
Vane, J. R., Bakhle, Y. S., & Botting, R. M. (1998) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.38.1.97 · Cited by 2,737 · see citing works
The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells
Batlle, E., Sancho, E., Francı́, C., Dominguez-Sola, D., Monfar, M., Baulida, J., & de Herreros, A. G. (2000) · Nature Cell Biology · doi:10.1038/35000034 · Cited by 2,671 · see citing works
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
Chandrasekharan, N. V., Dai, H., Roos, K. L. T., Evanson, N. K., Tomsik, J., Elton, T. S., & Simmons, D. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.162468699 · Cited by 1,989 · see citing works
Impaired immune and acute-phase responses in interleukin-6-deficient mice
Kopf, M., Baumann, H., Freer, G., Freudenberg, M., Lamers, M., Kishimoto, T., Zinkernagel, R., Bluethmann, H., & Köhler, G. (1994) · Nature · doi:10.1038/368339a0 · Cited by 1,768 · cited 1× · see citing works
“Nevertheless, the development of the blastocyst is compromised (Kopf et al., 1994; Salamonsen et al., 2000).”
Background
International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.
Coleman, R. A., Smith, W. L., & Narumiya, S. (1994) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06784-5 · Cited by 1,747 · see citing works
Biology of interleukin 1
Dinarello, C. A. (1988) · The FASEB Journal · doi:10.1096/fasebj.2.2.3277884 · Cited by 1,532 · see citing works
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion.
Comijn, J., Berx, G., Vermassen, P., Verschueren, K., van Grunsven, L. V., Bruyneel, E., Mareel, M., Huylebroeck, D., & van Roy, F. (2001) · Molecules and Cells · doi:10.1016/s1097-2765(01)00260-x · Cited by 1,464 · see citing works
Interleukin-6 in Biology and Medicine
Akira, S., Taga, T., & Kishimoto, T. (1993) · Advances in immunology · doi:10.1016/s0065-2776(08)60532-5 · Cited by 1,384 · see citing works
Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor
Hannum, C. H., Wilcox, C. J., Arend, W. P., Joslin, F. G., Dripps, D. J., Heimdal, P. L., Armes, L. G., Sommer, A., Eisenberg, S. P., & Thompson, R. C. (1990) · Nature · doi:10.1038/343336a0 · Cited by 1,122 · see citing works
Time of Implantation of the Conceptus and Loss of Pregnancy
Wilcox, A. J., Baird, D. D., & Weinberg, C. R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199906103402304 · Cited by 1,075 · see citing works
Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.
Gendler, S. J., Lancaster, C. A., Taylor‐Papadimitriou, J., Duhig, T., Peat, N., Burchell, J., Pemberton, L. F., Lalani, E., & Wilson, D. B. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)77254-2 · Cited by 976 · see citing works
Mucin-Type Glycoproteins
Strous, G. J., & Dekker, J. P. (1992) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409239209082559 · Cited by 927 · see citing works
cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily
Sims, J. E., March, C. J., Cosman, D. J., Widmer, M. B., MacDonald, H. R., McMahan, C. J., Grubin, C. E., Wignall, J. M., Jackson, J. L., Call, S. M., et al. (1988) · Science · doi:10.1126/science.2969618 · Cited by 877 · see citing works
Intercellular adhesion molecule-1
van de Stolpe, A., & van der Saag, P. T. (1996) · Journal of Molecular Medicine · doi:10.1007/bf00202069 · Cited by 802 · see citing works
The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex.
Gumbiner, B., Stevenson, B., & Grimaldi, A. (1988) · The Journal of cell biology · doi:10.1083/jcb.107.4.1575 · Cited by 799 · see citing works
Ligands for L-Selectin: Homing, Inflammation, and Beyond
Rosen, S. D. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.090501.080131 · Cited by 792 · see citing works
Prostaglandin Endoperoxide H Synthases-1 and -2
Smith, W. L., & DeWitt, D. L. (1996) · Advances in immunology · doi:10.1016/s0065-2776(08)60430-7 · Cited by 711 · see citing works
A form of circulating ICAM-1 in human serum
Rothlein, R., Mainolfi, E. A., Czajkowski, M., et al. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.147.11.3788 · Cited by 690 · see citing works
Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle.
Lessey, B. A., Damjanovich, L., Coutifaris, C., Castelbaum, A. J., Albelda, S. Μ., & Buck, C. A. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115835 · Cited by 640 · see citing works
Integrin switching regulates normal trophoblast invasion
Damsky, C. H., Librach, C. L., Lim, K.-H., Fitzgerald, M. L., McMaster, M., Janatpour, M. J., Zhou, Y., Logan, S. K., & Fisher, S. J. (1994) · Development · doi:10.1242/dev.120.12.3657 · Cited by 587 · see citing works
Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways.
Barth, A. M., Näthke, I., & Nelson, W. J. (1997) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(97)80122-6 · Cited by 573 · see citing works
LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing
Ye, X., Hama, K., Contos, J. J. A., Anliker, B., Inoue, A., Skinner, M. K., Suzuki, H., Amano, T., Kennedy, G., Arai, H., et al. (2005) · Nature · doi:10.1038/nature03505 · Cited by 563 · see citing works
Aberrant integrin expression in the endometrium of women with endometriosis
Lessey, B. A., Castelbaum, A. J., Sawin, S. W., Buck, C. A., Schinnar, R., Bilker, W. B., & Strom, B. L. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.79.2.7519194 · Cited by 514 · see citing works
A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development.
Riethmacher, D., Brinkmann, V., & Birchmeier, C. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.3.855 · Cited by 505 · see citing works
Deciphering the Cross-Talk of Implantation: Advances and Challenges
Paria, B. C., Reese, J., Das, S. K., & Dey, S. K. (2002) · Science · doi:10.1126/science.1071601 · Cited by 487 · see citing works
Hormonal Control of Ovoimplantation
Psychoyos, A. (1974) · Vitamins and hormones · doi:10.1016/s0083-6729(08)60999-1 · Cited by 481 · see citing works
Current Status of the Hypothesis that Mammalian Ovulation is Comparable to an Inflammatory Reaction
Espey, L. L. (1994) · Biology of Reproduction · doi:10.1095/biolreprod50.2.233 · Cited by 480 · see citing works
Trophoblast L-Selectin-Mediated Adhesion at the Maternal-Fetal Interface
Genbacev, O. D., Prakobphol, A., Foulk, R. A., Krtolica, A. R., Ilic, D., Singer, M. S., Yang, Z.-Q., Kiessling, L. L., Rosen, S. D., & Fisher, S. J. (2003) · Science · doi:10.1126/science.1079546 · Cited by 476 · see citing works
Cell membrane-associated mucins and their adhesion-modulating property
Hilkens, J., Ligtenberg, M. J. L., Vos, H. L., & Litvinov, S. V. (1992) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(92)90315-z · Cited by 453 · see citing works
Integrins as markers of uterine receptivity in women with primary unexplained infertility
Lessey, B. A., Castelbaum, A. J., Sawin, S. W., et al. (1995) · Fertility and Sterility · doi:10.1016/s0015-0282(16)57422-6 · Cited by 402 · see citing works
Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor
Lust, J. A., Donovan, K. A., Kline, M. P., Greipp, P. R., Kyle, R. A., & Maihle, N. J. (1992) · Cytokine · doi:10.1016/1043-4666(92)90043-q · Cited by 395 · see citing works
Further characterization of endometrial integrins during the menstrual cycle and in pregnancy
Lessey, B. A., Castelbaum, A. J., Buck, C. A., Lei, Y., Yowell, C. W., & Sun, J. (1994) · Fertility and Sterility · doi:10.1016/s0015-0282(16)56937-4 · Cited by 391 · see citing works
A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.
Wesseling, J., van der Valk, S. W., & Hilkens, J. (1996) · Molecular Biology of the Cell · doi:10.1091/mbc.7.4.565 · Cited by 384 · see citing works
Cadherins and catenins in development
Huber, O., Bierkamp, C., & Kemler, R. (1996) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(96)80110-4 · Cited by 349 · see citing works
A critical analysis of the accuracy, reproducibility, and clinical utility of histologic endometrial dating in fertile women
Murray, M. J., Meyer, W. R., Zaino, R. J., Lessey, B. A., Novotny, D. B., Ireland, K. M., Zeng, D., & Fritz, M. A. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.11.030 · Cited by 346 · see citing works
Histological dating of timed endometrial biopsy tissue is not related to fertility status
Coutifaris, C., Myers, E. R., Guzick, D. S., Diamond, M. P., Carson, S. A., Legro, R. S., McGovern, P. G., Schlaff, W. D., Carr, B. R., Steinkampf, M. P., et al. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.03.069 · Cited by 343 · see citing works
LIF: lots of interesting functions
Hilton, D. J. (1992) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(92)90505-4 · Cited by 339 · see citing works
Developmental expression of the cyclo-oxygenase-1 and cyclo-oxygenase-2 genes in the peri-implantation mouse uterus and their differential regulation by the blastocyst and ovarian steroids
Chakraborty, I., Das, S. K., Wang, J., & Dey, S. K. (1996) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0160107 · Cited by 337 · see citing works
Uterine leukocytes and decidualization
King, A. (2000) · Human Reproduction Update · doi:10.1093/humupd/6.1.28 · Cited by 334 · see citing works
Human Endometrial Mucin MUC1 Is Up-Regulated by Progesterone and Down-Regulated In Vitro by the Human Blastocyst1
Meseguer, M., Aplin, J., Caballero-Campo, P., et al. (2001) · Biology of Reproduction · doi:10.1095/biolreprod64.2.590 · Cited by 327 · see citing works
A morphological analysis of the early implantation stages in the rat
Enders, A. C., & Schläfke, S. (1967) · American Journal of Anatomy · doi:10.1002/aja.1001200202 · Cited by 319 · see citing works
Purification of a factor inducing differentiation of mouse myeloid leukemic M1 cells from conditioned medium of mouse fibroblast L929 cells.
Tomida, M., Yamamoto-Yamaguchi, Y., & Hozumi, M. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)90609-5 · Cited by 317 · see citing works
Embryonic implantation in mice is blocked by interleukin-1 receptor antagonist
Simón, C., Francés, A., Piquette, G. N., El-Danasouri, I., Zurawski, G., Dang, W., & Polan, M. L. (1994) · Endocrinology · doi:10.1210/endo.134.2.8299552 · Cited by 316 · see citing works
Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis
Ota, H., Igarashi, S., Sasaki, M., & Tanaka, T. (2001) · Human Reproduction · doi:10.1093/humrep/16.3.561 · Cited by 301 · see citing works
Endometrial leukocytes and menstruation
Salamonsen, L. A. (2000) · Human Reproduction Update · doi:10.1093/humupd/6.1.16 · Cited by 294 · see citing works
Leukaemia inhibitory factor mRNA concentration peaks in human endometrium at the time of implantation and the blastocyst contains mRNA for the receptor at this time
Jones, D. S., Sharkey, A., Fenwick, P., & Smith, S. K. (1994) · Reproduction · doi:10.1530/jrf.0.1010421 · Cited by 294 · see citing works
Interleukin-6 secretion in vitro is up-regulated in ectopic and eutopic endometrial stromal cells from women with endometriosis
Tseng, J. F., Ryan, I., Milam, T. D., Murai, J. T., Schriock, E. D., LANDERS, D. V., & Taylor, R. N. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.3.8772585 · Cited by 291 · see citing works
Expression and steroid hormonal control of Muc-1 in the mouse uterus.
Surveyor, G. A., Gendler, S. J., Pemberton, L. F., et al. (1995) · Endocrinology · doi:10.1210/endo.136.8.7628404 · Cited by 281 · see citing works
The human tumour-associated epithelial mucins are coded by an expressed hypervariable gene locus PUM
Swallow, D. M., Gendler, S. J., Griffiths, B. L., et al. (1987) · Nature · doi:10.1038/328082a0 · Cited by 281 · see citing works
Hydrosalpinges adversely affect markers of endometrial receptivity
Meyer, W. R., Castelbaum, A. J., Somkuti, S. G., Sagoskin, A. W., Doyle, M. B., Harris, J. E., & Lessey, B. A. (1997) · Human Reproduction · doi:10.1093/humrep/12.7.1393 · Cited by 281 · see citing works
The production of leukaemia inhibitory factor by human endometrium: presence in uterine flushings and production by cells in culture
Laird, S. M., Tuckerman, E. M., Dalton, C., Dunphy, B. C., Li, T. C., & Zhang, X. (1997) · Human Reproduction · doi:10.1093/humrep/12.3.569 · Cited by 280 · see citing works
Elevated Endometrial Androgen Receptor Expression in Women with Polycystic Ovarian Syndrome1
Apparao, K. B. C., Lovely, L. P., Gui, Y., Lininger, R. A., & Lessey, B. A. (2002) · Biology of Reproduction · doi:10.1095/biolreprod66.2.297 · Cited by 265 · see citing works
Cytokine-induced production of IFN-beta 2/IL-6 by freshly explanted human endometrial stromal cells. Modulation by estradiol-17 beta.
TABIBZADEH, S. S., Santhanam, U., Sehgal, P. B., & May, L. T. (1989) · The Journal of Immunology · doi:10.4049/jimmunol.142.9.3134 · Cited by 261 · see citing works
Cloning and Crystal Structure of Hematopoietic Prostaglandin D Synthase
Kanaoka, Y., Ago, H., Inagaki, E., Nanayama, T., Miyano, M., Kikuno, R. F., Fujii, Y., Eguchi, N., Toh, H., Urade, Y., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80374-8 · Cited by 258 · see citing works
Mucin Genes Expressed by Human Female Reproductive Tract Epithelia1
Gipson, I. K., Ho, S. B., Spurr-Michaud, S. J., Tisdale, A. S., Zhan, Q., Torlakovic, E., Pudney, J. A., Anderson, D. J., Toribara, N. W., & Hill, J. A. (1997) · Biology of Reproduction · doi:10.1095/biolreprod56.4.999 · Cited by 256 · see citing works
Cytosolic phospholipase A2α is crucial for ‘on-time’ embryo implantation that directs subsequent development
Song, H., Lim, H. J., Paria, B. C., Matsumoto, H., Swift, L. L., Morrow, J. D., Bonventre, J. V., & Dey, S. K. (2002) · Development · doi:10.1242/dev.129.12.2879 · Cited by 249 · see citing works
Modulation of leukemia inhibitory factor gene expression and protein biosynthesis in human endometrium
Arici, A. M., Engin, O., Attar, E., & Olive, D. L. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.6.7775640 · Cited by 247 · see citing works
Concentration of leukaemia inhibitory factor (LIF) in uterine flushing fluid is highly predictive of embryo implantation
Lédée, N. (2002) · Human Reproduction · doi:10.1093/humrep/17.1.213 · Cited by 242 · see citing works
Low-dose aspirin treatment improves ovarian responsiveness, uterine and ovarian blood flow velocity, implantation, and pregnancy rates in patients undergoing in vitro fertilization: a prospective, randomized, double-blind placebo-controlled assay
Rubinstein, M., Marazzi, A., & de Fried, E. P. (1999) · Fertility and Sterility · doi:10.1016/s0015-0282(99)00088-6 · Cited by 241 · see citing works
Cytological aspects of trophoblast‐uterine interaction in early implantation
Enders, A. C., & Schläfke, S. (1969) · American Journal of Anatomy · doi:10.1002/aja.1001250102 · Cited by 234 · see citing works
The role of T-helper cytokines in human reproduction
Lim, K. J. H., Odukoya, O. A., Ajjan, R., Li, T. C., Weetman, A. P., & Cooke, I. D. (2000) · Fertility and Sterility · doi:10.1016/s0015-0282(99)00457-4 · Cited by 233 · see citing works
L-selectin: mechanisms and physiological significance of ectodomain cleavage
Smalley, D. M., & Ley, K. F. (2005) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2005.tb00354.x · Cited by 232 · see citing works
Stage-Specific Expression of Cytokine and Receptor Messenger Ribonucleic Acids in Human Preimplantation Embryos1
Sharkey, A., Dellow, K., Blayney, M. L., Macnamee, M., Jones, D. S., & Smith, S. K. (1995) · Biology of Reproduction · doi:10.1095/biolreprod53.4.974 · Cited by 228 · see citing works
Localization of interleukin-1 type I receptor and interleukin-1 beta in human endometrium throughout the menstrual cycle
Simón, C., Piquette, G. N., Francés, A., & Polan, M. L. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.77.2.8345061 · Cited by 224 · see citing works
Regulated expression of cytokines in human endometrium throughout the menstrual cycle: dysregulation in habitual abortion
von Wolff, M. (2000) · Molecular Human Reproduction · doi:10.1093/molehr/6.7.627 · Cited by 223 · see citing works
Paracrine regulators of implantation
Simón, C., Martı́n, J. C., & Pellicer, A. (2000) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1053/beog.2000.0121 · Cited by 222 · see citing works
Endometrial Leukemia Inhibitory Factor (LIF) as a Possible Cause of Unexplained Infertility and Multiple Failures of Implantation
Hambartsoumian, E. (1998) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.1998.tb00345.x · Cited by 220 · see citing works
The polymorphic epithelial mucin MUC1 in human endometrium is regulated with maximal expression in the implantation phase.
Hey, N. A., Graham, R. A., Seif, M. W., et al. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.78.2.8106621 · Cited by 217 · see citing works
From rolling to arrest on blood vessels: leukocyte tap dancing on endothelial integrin ligands and chemokines at sub-second contacts
Alon, R., & Feigelson, S. W. (2002) · Seminars in Immunology · doi:10.1006/smim.2001.0346 · Cited by 212 · see citing works
Tumor Necrosis Factor-α Converting Enzyme/ADAM 17 Mediates MUC1 Shedding
Thathiah, A., Blobel, C., & Carson, D. D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m208326200 · Cited by 211 · see citing works
The effect of intercourse on pregnancy rates during assisted human reproduction
Tremellen, K. P., Valbuena, D., Landeras, J., et al. (2000) · Human Reproduction · doi:10.1093/humrep/15.12.2653 · Cited by 211 · see citing works
Spatial and Temporal Analyses of Integrin and Muc-1 Expression in Porcine Uterine Epithelium and Trophectoderm in Vitro1
Bowen, J. A., Bazer, F. W., & Burghardt, R. C. (1997) · Biology of Reproduction · doi:10.1095/biolreprod56.2.409 · Cited by 208 · see citing works
The immunocytochemical distribution of leukocytic subpopulations in human endometrium.
Kamat, B. R., & Isaacson, P. G. (1987) · PubMed · Cited by 207 · see citing works
Implantation: A cell biological paradox
Denker, H. (1993) · Journal of Experimental Zoology · doi:10.1002/jez.1402660606 · Cited by 207 · see citing works
Osteopontin and Its Receptor αvβ3Integrin Are Coexpressed in the Human Endometrium during the Menstrual Cycle But Regulated Differentially
Apparao, K. B. C., Murray, M. J., Fritz, M. A., Meyer, W. R., Chambers, A. F., Truong, P., & Lessey, B. A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.10.7906 · Cited by 198 · see citing works
Embryonic Regulation of Integrins β3,α 4, and α1 in Human Endometrial Epithelial Cells in Vitro1
Simón, C., Gimeno, M. J., Mercader, A., et al. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.8.4153 · Cited by 196 · see citing works
Spatial and Temporal Analyses of Integrin and Muc-1 Expression in Porcine Uterine Epithelium and Trophectoderm in Vivo1
Bowen, J. A., Bazer, F. W., & Burghardt, R. C. (1996) · Biology of Reproduction · doi:10.1095/biolreprod55.5.1098 · Cited by 193 · see citing works
THE CONTROL OF IMPLANTATION
Finn, C. A., & Martin, L. J. (1974) · Reproduction · doi:10.1530/jrf.0.0390195 · Cited by 192 · see citing works
MOLECULAR MECHANISMS OF PROSTAGLANDIN TRANSPORT
Schuster, V. L. (1998) · Annual Review of Physiology · doi:10.1146/annurev.physiol.60.1.221 · Cited by 188 · see citing works
Pinocytotic activity of the uterus of the rat
Enders, A. C., & Nelson, D. M. (1973) · American Journal of Anatomy · doi:10.1002/aja.1001380302 · Cited by 183 · see citing works
IMPLANTATION: A CELL BIOLOGICAL PARADOX
Dender, H. W. (1993) · Cited by 182 · see citing works
Prostaglandin transport
Schuster, V. L. (2002) · Prostaglandins & Other Lipid Mediators · doi:10.1016/s0090-6980(02)00061-8 · Cited by 182 · see citing works
Integrin-mediated signal transduction
Longhurst, C. M., & Jennings, L. K. (1998) · Cellular and Molecular Life Sciences (CMLS) · doi:10.1007/s000180050180 · Cited by 181 · see citing works
Progressive rise in the expression of interleukin-6 in human endometrium during menstrual cycle is initiated during the implantation window
TABIBZADEH, S. S., Kong, Q. F., Babaknia, A., & May, L. T. (1995) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a135793 · Cited by 173 · see citing works
A randomized, double-blind, placebo-controlled trial of heparin and aspirin for women with in vitro fertilization implantation failure and antiphospholipid or antinuclear antibodies
Stern, C. J., Chamley, L., Norris, H., et al. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(03)00610-1 · Cited by 172 · see citing works
Cytokines and embryo implantation
Simón, C., Moreno, C., Remohi, J., Sr., & Pellicer, A. (1998) · Journal of Reproductive Immunology · doi:10.1016/s0165-0378(98)00017-5 · Cited by 171 · see citing works
MT1-MMP mediates MUC1 shedding independent of TACE/ADAM17
Thathiah, A., & Carson, D. D. (2004) · Biochemical Journal · doi:10.1042/bj20040513 · Cited by 169 · see citing works
Direct Regulation of β3-Integrin Subunit Gene Expression by HOXA10 in Endometrial Cells
Daftary, G. S., Troy, P. J., Bagot, C. N., Young, S. L., & Taylor, H. S. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.3.0792 · Cited by 169 · see citing works
Endometrial dating and determination of the window of implantation in healthy fertile women
Acosta, A. A., Elberger, L., Borghi, M., et al. (2000) · Fertility and Sterility · doi:10.1016/s0015-0282(99)00605-6 · Cited by 164 · see citing works
Tumor Necrosis Factor-α Messenger Ribonucleic Acid and Protein in Human Endometrium1
Hunt, J. S., Chen, H.-L., Hu, X.-L., & TABIBZADEH, S. S. (1992) · Biology of Reproduction · doi:10.1095/biolreprod47.1.141 · Cited by 160 · see citing works
Leukocyte Migration Is Regulated by L-Selectin Endoproteolytic Release
Venturi, G. M., Tu, L., Kadono, T., Khan, A. I., Fujimoto, Y., Oshel, P. E., Bock, C. B., Miller, A. S., Albrecht, R. M., Kubes, P., et al. (2003) · Immunity · doi:10.1016/s1074-7613(03)00295-4 · Cited by 155 · see citing works
Uterine Receptivity for Blastocyst Implantation
Yoshinaga, K. (1988) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1988.tb22279.x · Cited by 143 · see citing works
Two pathways of progesterone action in the human endometrium: implications for implantation and contraception
Lessey, B. A. (2003) · Steroids · doi:10.1016/j.steroids.2003.09.004 · Cited by 141 · see citing works
Localization of laminin, fibronectin, E-cadherin, and integrins in endometrium and endometriosis
Béliard, A., Donnez, J., Nisolle, M., & Foidart, J. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)81909-7 · Cited by 141 · see citing works
Use of integrins to date the endometrium
Lessey, B. A., Castelbaum, A. J., Wolf, L., Greene, W., Paulson, M., Meyer, W. R., & Fritz, M. A. (2000) · Fertility and Sterility · doi:10.1016/s0015-0282(99)00604-4 · Cited by 138 · see citing works
Purification of a murine leukemia inhibitory factor from Krebs ascites cells
Hilton, D. J., Nicola, N. A., & Metcalf, D. (1988) · Analytical Biochemistry · doi:10.1016/0003-2697(88)90200-x · Cited by 137 · see citing works
Coexpression of pinopodes and leukemia inhibitory factor, as well as its receptor, in human endometrium
Aghajanova, L., Stavreus-Evers, A. C., Nikas, Y., et al. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(02)04830-6 · Cited by 136 · see citing works
Formation of pinopodes in human endometrium is associated with the concentrations of progesterone and progesterone receptors
Stavreus-Evers, A. C., Nikas, G., Sahlin, L., et al. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(01)01993-8 · Cited by 133 · see citing works
The Leukemia Inhibitory Factor and Its Receptor
Gearing, D. P. (1993) · Advances in immunology · doi:10.1016/s0065-2776(08)60497-6 · Cited by 132 · see citing works
Pinopodes as markers of endometrial receptivity in clinical practice
Nikas, G. (1999) · Human Reproduction · doi:10.1093/humrep/14.suppl_2.99 · Cited by 132 · see citing works
cDNA cloning, expression and characterization of human prostaglandin F synthase1
Suzuki-Yamamoto, T., Nishizawa, M., Fukui, M., Okuda‐Ashitaka, E., Nakajima, T., Ito, S., & Watanabe, K. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01551-3 · Cited by 131 · see citing works
Modulation of Muc-1 mucin expression in the mouse uterus during the estrus cycle, early pregnancy and placentation
Braga, V. M. M., & Gendler, S. J. (1993) · Journal of Cell Science · doi:10.1242/jcs.105.2.397 · Cited by 129 · see citing works
Human chorionic gonadotropin and growth factors at the embryonic-endometrial interface control leukemia inhibitory factor (LIF) and interleukin 6 (IL-6) secretion by human endometrial epithelium.
d'Hauterive, S. P., Charlet-Renard, C., Berndt, S., Dubois, M., Munaut, C., Goffin, F., Hagelstein, M., Nöel, A., Hazout, A., Foidart, J., et al. (2004) · Human Reproduction · doi:10.1093/humrep/deh450 · Cited by 129 · see citing works
Resolution and purification of three distinct factors produced by Krebs ascites cells which have differentiation-inducing activity on murine myeloid leukemic cell lines.
Hilton, D. J., Nicola, N. A., Gough, N. M., et al. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76530-2 · Cited by 128 · see citing works
Distinct Regulation of Cyclooxygenase-2 by Interleukin-1β in Normal and Endometriotic Stromal Cells
Wu, M., Wang, C.-A., Lin, C.-C., Chen, L.-C., Chang, W., & Tsai, S. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1612 · Cited by 128 · see citing works
Expression of cyclo-oxygenase in human endometrium during the implantation period
Marions, L. (1999) · Molecular Human Reproduction · doi:10.1093/molehr/5.10.961 · Cited by 127 · see citing works
MUC1 in secretory phase endometrium: expression in precisely dated biopsies and flushings from normal and recurrent miscarriage patients
Hey, N. A., Li, T. C., Devine, P. L., et al. (1995) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a135762 · Cited by 127 · see citing works
Maternal Hoxa10 is required for pinopod formation in the development of mouse uterine receptivity to embryo implantation
Bagot, C. N., Kliman, H. J., & Taylor, H. S. (2001) · Developmental Dynamics · doi:10.1002/dvdy.1209 · Cited by 126 · see citing works
Isolation and culture of human endometrial cells in a three-dimensional culture system
Bentin-Ley, U., Pedersen, B. K., Lindenberg, S., et al. (1994) · Reproduction · doi:10.1530/jrf.0.1010327 · Cited by 125 · see citing works
Cytokines in Implantation
Salamonsen, L. A., Dimitriadis, E., & Robb, L. (2000) · Seminars in Reproductive Medicine · doi:10.1055/s-2000-12567 · Cited by 125 · see citing works
Presence of uterine pinopodes at the embryo endometrial interface during human implantation in vitro
Bentin-Ley, U., Sjogren, A., Nilsson, O., et al. (1999) · Human Reproduction · doi:10.1093/humrep/14.2.515 · Cited by 124 · see citing works
Human glutathione dependent prostaglandin E synthase: gene structure and regulation
Forsberg, L., Leeb, L., Thorén, S., et al. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01367-3 · Cited by 123 · see citing works
Leukaemia inhibitory factor and the regulation of pre‐implantation development of the mammalian embryo
Stewart, C. L. (1994) · Molecular Reproduction and Development · doi:10.1002/mrd.1080390217 · Cited by 122 · see citing works
Progesterone Inhibits Activation of Latent Matrix Metalloproteinase (MMP)-2 by Membrane-Type 1 MMP: Enzymes Coordinately Expressed in Human Endometrium1
Zhang, J., Hampton, A. L., Nie, G., & Salamonsen, L. A. (2000) · Biology of Reproduction · doi:10.1095/biolreprod62.1.85 · Cited by 119 · see citing works
Ultrastructure of mouse uterine surface epithelium under different estrogenic influences
Nilsson, O. R. (1958) · Journal of Ultrastructure Research · doi:10.1016/s0022-5320(58)90009-1 · Cited by 118 · see citing works
Leukaemia inhibitory factor in human endometrium throughout the menstrual cycle
Vogiagis, D., Marsh, M. M., Fry, R. C., et al. (1996) · Journal of Endocrinology · doi:10.1677/joe.0.1480095 · Cited by 116 · see citing works
Progesterone stimulates calcitonin gene expression in the uterus during implantation.
Ding, Y. Q., Zhu, L., Bagchi, M. K., et al. (1994) · Endocrinology · doi:10.1210/endo.135.5.7956949 · Cited by 116 · see citing works
The cell biological basis of human implantation
Aplin, J. (2000) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1053/beog.2000.0116 · Cited by 114 · see citing works
Molecular Cloning and Expression of Human Prostacyclin Synthase
Miyata, A., Hara, S., Yokoyama, C., et al. (1994) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1994.1652 · Cited by 112 · see citing works
Human endometrial MUC1 carries keratan sulfate: characteristic glycoforms in the luminal epithelium at receptivity
Aplin, J. (1998) · Glycobiology · doi:10.1093/glycob/8.3.269 · Cited by 112 · see citing works
Mucin (Muc-1) Expression is Differentially Regulated in Uterine Luminal and Glandular Epithelia of the Baboon (Papio Anubis)1
Hild-Petito, S. A., Fazleabas, A. T., Julian, J. A., et al. (1996) · Biology of Reproduction · doi:10.1095/biolreprod54.5.939 · Cited by 111 · see citing works
Progesterone Induces Calcitonin Gene Expression in Human Endometrium within the Putative Window of Implantation
Kumar, S., Zhu, L.-J., Polihronis, M., Cameron, S. T., Baird, D. T., Schatz, F., Dua, A., Ying, Y.-K., Bagchi, M. K., & Bagchi, I. C. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.12.5328 · Cited by 109 · see citing works
Embryonic implantation and leukocyte transendothelial migration: different processes with similar players?
Domı́nguez, F., Yáñez‐Mó, M., Sánchez‐Madrid, F., et al. (2005) · The FASEB Journal · doi:10.1096/fj.05-3781hyp · Cited by 106 · see citing works
Scanning electron microscopy of postovulatory human endometrium in spontaneous cycles and cycles stimulated by hormone treatment
Martel, D., Frydman, R., Glissant, M., et al. (1987) · Journal of Endocrinology · doi:10.1677/joe.0.1140319 · Cited by 105 · see citing works
Expression, Localization, and Signaling of PGE2and EP2/EP4 Receptors in Human Nonpregnant Endometrium across the Menstrual Cycle
Milne, S. A., Perchick, G. B., Boddy, S. C., et al. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.9.7856 · Cited by 103 · see citing works
Integrin-Mediated Adhesion and Signaling during Blastocyst Implantation
Wang, J., & Armant, D. R. (2002) · Cells Tissues Organs · doi:10.1159/000066970 · Cited by 102 · see citing works
Soluble gp130 is Up-Regulated in the Implantation Window and Shows Altered Secretion in Patients with Primary Unexplained Infertility
Sherwin, J. R. A., Smith, S. K., Wilson, A., et al. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.8.8766 · Cited by 102 · see citing works
Calcitonin Is a Progesterone-Regulated Marker That Forecasts the Receptive State of Endometrium during Implantation
Zhu, L.-J., Cullinan-Bove, K., Polihronis, M., Bagchi, M. K., & Bagchi, I. C. (1998) · Endocrinology · doi:10.1210/endo.139.9.6178 · Cited by 101 · see citing works
Human endometrial stromal cells as a source of soluble intercellular adhesion molecule (ICAM)-l molecules
Somigliana, E., Vigand, P., Gaffuri, B., Guarneri, D., Busacca, M., & Vignali, M. (1996) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a019353 · Cited by 100 · see citing works
Leukaemia inhibitory factor (LIF) gene mutations in women with unexplained infertility and recurrent failure of implantation after IVF and embryo transfer
Steck, T., Giess, R., Suetterlin, M. W., et al. (2003) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/s0301-2115(03)00315-4 · Cited by 99 · see citing works
Treatment of repeated unexplained in vitro fertilization failure with intravenous immunoglobulin: a randomized, placebo-controlled Canadian trial
Stephenson, M. D., & Fluker, M. R. (2000) · Fertility and Sterility · doi:10.1016/s0015-0282(00)01622-8 · Cited by 98 · see citing works
Expression of cadherins and integrins in human endometrium throughout the menstrual cycle
van der Linden, P. J. Q., de Goeij, A. F. P. M., Dunselman, G. A. J., Erkens, H. W. H., & Evers, J. L. H. (1995) · Fertility and Sterility · doi:10.1016/s0015-0282(16)57599-2 · Cited by 97 · see citing works
Luteal Phase Support in in vitro Fertilization: Meta-Analysis of Randomized Trials
Nosarka, S., Kruger, T. F., Siebert, I., & Grove, D. (2005) · Gynecologic and Obstetric Investigation · doi:10.1159/000084546 · Cited by 97 · see citing works
Expression of cadherins and CD44 isoforms in human endometrium and peritoneal endometriosis
Poncelet, C., Leblanc, M., Walker, F., Soriano, D., Feldmann, G., Madélénat, P., Scoazec, J., & Daraï, É. (2002) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1034/j.1600-0412.2002.810302.x · Cited by 97 · see citing works
The Role of Leukocyte Traffic and Activation in Parturition
Yellon, S. M., Mackler, A. M., & Kirby, M. A. (2003) · Journal of the Society for Gynecologic Investigation · doi:10.1016/s1071-5576(03)00116-3 · Cited by 95 · see citing works
Correlation of Endometrial Maturation with Four Methods of Estimating Day of Ovulation
Shoupe, D., Mishell, D. R., Lacarra, M., et al. (1989) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-198910000-00018 · Cited by 94 · see citing works
Cyclooxygenase-2 expression in deep endometriosis and matched eutopic endometrium
Matsuzaki, S., Canis, M. J., Pouly, J. L., Wattiez, A., Okamura, K., & Mage, G. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.03.059 · Cited by 94 · see citing works
The Role of Integrins in Reproduction
Bowen, J. A., & Hunt, J. S. (2000) · Proceedings of The Society for Experimental Biology and Medicine · doi:10.1046/j.1525-1373.2000.22348.x · Cited by 93 · see citing works
Scanning Electron Microscopic study of the Human Endometrium
Johannisson, E., & Nilsson, L. (1972) · Fertility and Sterility · doi:10.1016/s0015-0282(16)39188-9 · Cited by 93 · see citing works
Infertility: Beta-1 integrin cell adhesion molecules in the endometrium of fertile and infertile women
Klentzeris, L. D., Bulmer, J. N., Trejdosiewicz, L. K., et al. (1993) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a138231 · Cited by 92 · see citing works
The signal transducer gp130 is shared by interleukin-6 family of haematopoietic and neurotrophic cytokines.
Taga, T. (1997) · Annals medicus · doi:10.3109/07853899708998744 · Cited by 89 · see citing works
Reduction of Mucin-1 Expression during the Receptive Phase in the Rat Uterus1
DeSouza, M. M., Mani, S. K., Julian, J. A., et al. (1998) · Biology of Reproduction · doi:10.1095/biolreprod58.6.1503 · Cited by 88 · see citing works
Prostaglandin (PG) F2αReceptor Expression and Signaling in Human Endometrium: Role of PGF2αin Epithelial Cell Proliferation
Milne, S. A., & Jabbour, H. N. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021368 · Cited by 86 · see citing works
Epidermal Growth Factor and Sex Steroids Dynamically Regulate a Marker of Endometrial Receptivity in Ishikawa Cells1
Somkuti, S. G., Yuan, L., Fritz, M. A., et al. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.7.4102 · Cited by 85 · see citing works
Enhancement of interleukin 6 cytostatic effect on human breast carcinoma cells by soluble IL-6 receptor from urine and reversion by monoclonal antibody
Novick, D. (1992) · Cytokine · doi:10.1016/1043-4666(92)90029-q · Cited by 85 · see citing works
Molecular mechanisms for focal adhesion assembly through regulation of protein–protein interactions
Gilmore, A. P., & Burridge, K. (1996) · Structure · doi:10.1016/s0969-2126(96)00069-x · Cited by 84 · see citing works
The effect of various doses of mifepristone on endometrial leukaemia inhibitory factor expression in the midluteal phase--an immunohistochemical study
Danielsson, K. G., Swahn, M. L., & Bygdeman, M. (1997) · Human Reproduction · doi:10.1093/humrep/12.6.1293 · Cited by 83 · see citing works
MUC1 as a Cell Surface and Secretory Component of Endometrial Epithelium: Reduced Levels in Recurrent Miscarriage
Aplin, J., Hey, N. A., & Li, T. C. (1996) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.1996.tb00042.x · Cited by 79 · see citing works
Integrin expression in normal and out-of-phase endometria
Creus, M., Balasch, J. C., Ordï, J., et al. (1998) · Human Reproduction · doi:10.1093/humrep/13.12.3460 · Cited by 79 · see citing works
Mechanisms of endometrial control of trophoblast invasion.
Bischof, P., Meisser, A., & Campana, A. (2000) · PubMed · Cited by 79 · see citing works
Ultrastructure of mouse uterine surface epithelium under different estrogenic influences
Nilsson, O. R. (1958) · Journal of Ultrastructure Research · doi:10.1016/s0022-5320(58)90017-0 · Cited by 78 · see citing works
Temporal and morphologic characteristics of pinopod expression across the secretory phase of the endometrial cycle in normally cycling women with proven fertility
Usadi, R., Murray, M. J., Bagnell, R. C., et al. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(02)04929-4 · Cited by 78 · see citing works
Calcitonin Down-regulates E-cadherin Expression in Rodent Uterine Epithelium during Implantation
Li, Q., Wang, J., Armant, D. R., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203555200 · Cited by 76 · see citing works
Hyaluronic acid can successfully replace albumin as the sole macromolecule in a human embryo transfer medium
Simon, A., Safran, A., Revel, A., et al. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(03)00349-2 · Cited by 74 · see citing works
Self-citation
Intercellular adhesion molecule-1 (ICAM-1) gene polymorphisms in endometriosis
Viganò, P. (2003) · Molecular Human Reproduction · doi:10.1093/molehr/gag002 · Cited by 74 · see citing works
Regional specialization of the cell membrane-associated, polymorphic mucin (MUC1) in human uterine epithelia
DeLoia, J. A., Krasnow, J. S., Brekosky, J., et al. (1998) · Human Reproduction · doi:10.1093/humrep/13.10.2902 · Cited by 72 · see citing works
Endometriosis-associated infertility
Buyalos, R. P., & Agarwal, S. K. (2000) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/00001703-200010000-00006 · Cited by 70 · see citing works
Endometrial integrin expression in women undergoing in vitro fertilization and the association with subsequent treatment outcome
Thomas, K., Thomson, A. J. M., Wood, S., et al. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(03)00792-1 · Cited by 68 · see citing works
An Immunohistochemical Study of Lymphoid Tissue in Human Endometrium
Marshall, R. J., & Jones, D. B. (1988) · International Journal of Gynecological Pathology · doi:10.1097/00004347-198809000-00003 · Cited by 68 · see citing works
Endometrial differentiation in the peri-implantation phase of women with recurrent miscarriage: a morphological and immunohistochemical study
Serle, E., Aplin, J., Li, T. C., et al. (1994) · Fertility and Sterility · doi:10.1016/s0015-0282(16)57063-0 · Cited by 68 · see citing works
Purification of soluble cytokine receptors from normal human urine by ligand-affinity and immunoaffinity chromatography
Novick, D., Engelmann, H., Wallach, D., Leitner, O., Revel, M., & Rubinstein, M. (1990) · Journal of Chromatography A · doi:10.1016/s0021-9673(01)93767-7 · Cited by 67 · see citing works
Leptin Upregulates β3-Integrin Expression and Interleukin-1β Upregulates Leptin and Leptin Receptor Expression in Human Endometrial Epithelial Cell Cultures
González, R. R., & Leavis, P. C. (2001) · Endocrine · doi:10.1385/endo:16:1:21 · Cited by 67 · see citing works
The expression of soluble intercellular adhesion molecule-1 in endometriosis
Wu, M., Yang, B., Hsu, C., Lee, Y.-C., & Huang, K. (1998) · Fertility and Sterility · doi:10.1016/s0015-0282(98)00384-7 · Cited by 67 · see citing works
The production of placental protein 14 and interleukin 6 by human endometrial cells in culture
Laird, S. M., Li, T. C., & Bolton, A. E. (1993) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a138144 · Cited by 67 · see citing works
Concentrations of interleukin (IL)-1α, IL-1 soluble receptor type II (IL-1 sRII) and IL-1 receptor antagonist (IL-1 Ra) in the peritoneal fluid and serum of infertile women with endometriosis
Kondera‐Anasz, Z., Sikora, J., Mielczarek‐Palacz, A., & Jońca, M. (2005) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2005.04.019 · Cited by 65 · see citing works
Reduced Expression of αvβ3 Integrin in the Endometrium of Unexplained Infertility Patients with Recurrent IVF-ET Failures: Improvement by Danazol Treatment
Tei, C., Maruyama, T., Kuji, N., et al. (2003) · Journal of Assisted Reproduction and Genetics · doi:10.1023/a:1021254620888 · Cited by 64 · see citing works
Implantation Rates after Two, Three, or Five Days of Embryo Culture
Santos, M. J. D. L., Mercader, A., Galán, A., et al. (2003) · Placenta · doi:10.1016/s0143-4004(03)00172-3 · Cited by 64 · see citing works
Differential expression of L-selectin ligand in the endometrium during the menstrual cycle
Lai, T., Shih, I., Vlahos, N., et al. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.11.040 · Cited by 63 · see citing works
Alteration of E-cadherin, α-and β-catenin mRNA expression in human uterine endometrium during the menstrual cycle
Fujimoto, J., Ichigo, S., Hori, M., et al. (1996) · Gynecological Endocrinology · doi:10.3109/09513599609027987 · Cited by 62 · see citing works
Endometrial and Myometrial Prostaglandin Release during the Menstrual Cycle in Relation to Menstrual Blood Loss*
RESS, M. C. P., Anderson, A. B. M., Demers, L. M., & TURNBULL, A. C. (1984) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-58-5-813 · Cited by 61 · see citing works
Low-dose aspirin does not improve ovarian responsiveness or pregnancy rate in IVF and ICSI patients: a randomized, placebo-controlled double-blind study
Päkkilä, M., Rasanen, J. P., Heinonen, S. T., et al. (2005) · Human Reproduction · doi:10.1093/humrep/dei020 · Cited by 61 · see citing works
Expression of Human Prostaglandin Transporter in the Human Endometrium across the Menstrual Cycle
Kang, J., Chapdelaine, P., Parent, J., Madore, É., Laberge, P. Y., & Fortier, M. A. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1482 · Cited by 59 · see citing works
Tumor Necrosis Factor α Stimulates MUC1 Synthesis and Ectodomain Release in a Human Uterine Epithelial Cell Line
Thathiah, A., Brayman, M. J., Dharmaraj, N., et al. (2004) · Endocrinology · doi:10.1210/en.2004-0399 · Cited by 59 · see citing works
What Makes an Embryo Stick?
Fazleabas, A. T., & Kim, J. (2003) · Science · doi:10.1126/science.1081277 · Cited by 58 · see citing works
The interleukin-1 receptor in Raji human B-lymphoma cells. Molecular characterization and evidence for receptor-mediated activation of gene expression
Horuk, R., & McCubrey, J. A. (1989) · Biochemical Journal · doi:10.1042/bj2600657 · Cited by 57 · see citing works
Expression of intercellular adhesion molecules ICAM-1 and ICAM-2 in human endometrium: regulation by interferon-gamma
Thomson, A. J. (1999) · Molecular Human Reproduction · doi:10.1093/molehr/5.1.64 · Cited by 57 · see citing works
Coordination of interleukin-6 biology by membrane bound and soluble receptors
Rose‐John, S. (2001) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-0685-0_19 · Cited by 55 · see citing works
Regulation of functional steroid receptors and ligand-induced responses in telomerase-immortalized human endometrial epithelial cells
Hombach‐Klonisch, S., Kehlen, A., Fowler, P., Huppertz, B., Jugert, J. F., Bischoff, G., Schluter, E. W., Buchmann, J., & Klonisch, T. C. (2004) · Journal of Molecular Endocrinology · doi:10.1677/jme.1.01550 · Cited by 55 · see citing works
Human endometrial interleukin-6 (IL-6): in vivo messenger ribonucleic acid expression, in vitro protein production, and stimulation thereof by IL-1β
Vandermolen, D. T., & Gu, Y. (1996) · Fertility and Sterility · doi:10.1016/s0015-0282(16)58628-2 · Cited by 55 · see citing works
Association of monocytes and neutrophils with early events of blastocyst implantation in mice
McMaster, M., Dey, S. K., & Andrews, G. K. (1993) · Reproduction · doi:10.1530/jrf.0.0990561 · Cited by 54 · see citing works
The assessment of LIF in uterine flushing--a possible new diagnostic tool in states of impaired fertility.
Mikołajczyk, M., Skrzypczak, J., Szymanowski, K., et al. (2003) · PubMed · Cited by 53 · see citing works
MUC 1: a genetic susceptibility to infertility?
Horne, A. W., WHITE, J. O., Margara, R. A., et al. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04502-5 · Cited by 52 · see citing works
Modulation of integrin expression in endometrial stromal cells in vitro.
Grosskinsky, C. M., Yowell, C. W., Sun, J., et al. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.6.8964827 · Cited by 50 · see citing works
Immunohistochemical localisation of cyclooxygenase in the human uterus
REES, M. C. P., Parry, D. M., Anderson, A. B. M., et al. (1982) · Prostaglandins · doi:10.1016/0090-6980(82)90047-8 · Cited by 50 · see citing works
Human uterodomes (pinopods) do not display pinocytotic function
Adams, S. (2002) · Human Reproduction · doi:10.1093/humrep/17.8.1980 · Cited by 48 · see citing works
Host defense against infections and inflammations: Role of the multifunctional IL-6/IFN-β2 cytokine
Revel, M. (1989) · Cellular and Molecular Life Sciences · doi:10.1007/bf01990505 · Cited by 47 · see citing works
The Differential Expression of Intercellular Adhesion Molecule‐1 (ICAM‐1) and Regulation by Interferon‐Gamma during the Pathogenesis of Endometriosis
Wu, M., Yang, B., Lee, Y., Wu, P., & Hsu, C. (2004) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2004.00171.x · Cited by 45 · see citing works
Human Endometrial Leukemia Inhibitory Factor and Interleukin-6: Control of Secretion by Transforming Growth Factor-β-Related Members
d'Hauterive, S. P., Charlet-Renard, C., Dubois, M., Berndt, S., Goffin, F., Foidart, J., & Geenen, V. (2005) · Neuroimmunomodulation · doi:10.1159/000084848 · Cited by 45 · see citing works
Endometrial expression and secretion of interleukin-6 throughout the menstrual cycle
von Wolff, M., Thaler, C., Zepf, C., et al. (2002) · Gynecological Endocrinology · doi:10.1080/gye.16.2.121.129 · Cited by 44 · see citing works
8 Endometriosis-associated infertility
Haney, A. F. (1993) · Baillière s Clinical Obstetrics and Gynaecology · doi:10.1016/s0950-3552(05)80464-x · Cited by 43 · see citing works
Tumor necrosis factor is present in maternal sera and embryo culture fluids during in vitro fertilization
Witkin, S. S., Liu, H.-C., Davis, O., et al. (1991) · Journal of Reproductive Immunology · doi:10.1016/0165-0378(91)90008-e · Cited by 39 · see citing works
Heparanase improves mouse embryo implantation
Revel, A., Helman, A., Koler, M., et al. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.11.008 · Cited by 37 · see citing works
Self-citation
Cycle-Dependent Expression of Interleukin-1 Receptor Type II in the Human Endometrium1
Boucher, A., Aris, A., Al-Akoum, M., Bossù, P., & Akoum, A. (2001) · Biology of Reproduction · doi:10.1095/biolreprod65.3.890 · Cited by 37 · see citing works
Increased pregnancy rates after IVF/ET with intravenous immunoglobulin treatment in women with elevated circulating C56+ cells.
Cb, C., & Goodman, C. (2000) · PubMed · Cited by 37 · see citing works
Endometrial interleukin-6 in vitro is not regulated directly by female steroid hormones, but by pro-inflammatory cytokines and hypoxia
von Wolff, M. (2002) · Molecular Human Reproduction · doi:10.1093/molehr/8.12.1096 · Cited by 34 · see citing works
Detection of endometrial pinopodes by light microscopy
Develioğlu, O. H., Nikas, G., Hsiu, J.-G., et al. (2000) · Fertility and Sterility · doi:10.1016/s0015-0282(00)00717-2 · Cited by 33 · see citing works

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The role of infection in miscarriage
Giakoumelou, S., Wheelhouse, N., Cuschieri, K., Entrican, G., Howie, S. E. M., & Horne, A. W. (2016) · Human Reproduction Update · doi:10.1093/humupd/dmv041 · Cited by 464 · see citing works
Estradiol and Progesterone Regulate the Migration of Mast Cells from the Periphery to the Uterus and Induce Their Maturation and Degranulation
Jensen, F., Woudwyk, M., Teles, A., Woidacki, K., Taran, F., Costa, S., Malfertheiner, S. F., & Zenclussen, A. C. (2010) · PLoS ONE · doi:10.1371/journal.pone.0014409 · Cited by 145 · see citing works
“histamine, tryptases, MMPs, VEGF, [2,30,45,47].”
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MicroRNA signature and regulatory functions in the endometrium during normal and disease states
Pan, Q., & Chegini, N. (2008) · Seminars in Reproductive Medicine · doi:10.1055/s-0028-1096128 · Cited by 134 · see citing works
Eutopic endometrium in women with endometriosis: ground zero for the study of implantation defects
Lessey, B., Lebovic, D., & Taylor, R. (2013) · Seminars in Reproductive Medicine · doi:10.1055/s-0032-1333476 · Cited by 113 · see citing works
The roles of leptin and adiponectin at the fetal-maternal interface in humans
Dos Santos, E., Duval, F., Vialard, F., & Dieudonné, M.-N. (2015) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2015-0031 · Cited by 52 · see citing works
Endometrial gene expression in early pregnancy: Lessons from human ectopic pregnancy
Savaris, R. F., Hamilton, A. E., Lessey, B. A., & Giudice, L. C. (2008) · Reproductive Sciences · doi:10.1177/1933719108317585 · Cited by 37 · see citing works

Preliminary Radiogrammetric Analysis of the Bone Recovery Phase in Adolescents with Down??s Syndrome
Garn, S. M., Gall, J. C., & Nagy, J. M. (1972) · Investigative Radiology · doi:10.1097/00004424-197203000-00005 · Cited by 7 · see citing works
Experiences and Perceptions of Receptivity among Latinos and non-Latinos in the US Southeast: Lessons from Community Dialogues in an Evolving Immigrant Gateway City
Schuch, J. C., Smith, H. A., & Harden, S. B. (2021) · Southeastern geographer · doi:10.1353/sgo.2021.0011 · Cited by 1 · see citing works
Sexual Receptivity in Insects
Ringo, J. M. (1996) · Annual Review of Entomology · doi:10.1146/annurev.ento.41.1.473 · Cited by 101 · see citing works
Sexual Receptivity in Insects
Ringo, J. M. (1996) · Annual Review of Entomology · doi:10.1146/annurev.en.41.010196.002353 · Cited by 133 · see citing works
Inheritance Pattern of Female Receptivity inDrosophila prolongata
Hitoshi, Y., Ishikawa, Y., & Matsuo, T. (2016) · ZOOLOGICAL SCIENCE · doi:10.2108/zs160047 · Cited by 9 · see citing works

Authors: Achache, H., & Revel, A.
Affiliations: Hadassah Medical Center (IL)
Corresponding author: Achache, Hanna
ORCID: Revel, Ariel
Venue: Human Reproduction Update
Publisher: Oxford University Press (OUP)
Published: 2006-09-18
Volume: 12
Issue: 6
Pages: 731-746
ISSN: 1355-4786 (ISSN-L)
1460-2369
DOI: 10.1093/humupd/dml004
OpenAlex: W2130463115
Cited by: 952
References: 209
Citations by year: 2026: 55 · 2025: 73 · 2024: 50 · 2023: 72 · 2022: 80 · 2021: 73 · 2020: 85 · 2019: 61 · 2018: 40 · 2017: 47 · 2016: 45 · 2015: 39 · 2014: 37 · 2013: 36 · 2012: 36
FWCI: 1.58
Type: journal article
Language: en
Open access: closed
Locations: Human Reproduction Update (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
Keywords: endometrial receptivity, embryo implantation, blastocyst adhesion, embryo-uterus interaction, implantation window, endometrial biopsy, adhesion molecules, cytokines, growth factors, lipids, implantation failure
MeSH terms: Animals, Endometrium, Female, Humans, Infertility, Female, Embryo Implantation, Pregnancy, Prostaglandins, Biomarkers, Cell Adhesion Molecules, Cytokines

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Endometrial receptivity markers, the journey to successful embryo implantation.

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