Procyanidin content and variation in some commonly consumed foods
Open accessAbstract
Procyanidins are a subclass of flavonoids found in commonly consumed foods that have attracted increasing attention due to their potential health benefits. However, little is known regarding their dietary intake levels because detailed quantitative information on the procyanidin profiles present in many food products is lacking. Therefore, the procyanidin content of red wine, chocolate, cranberry juice and four varieties of apples has been determined. On average, chocolate and apples contained the largest procyanidin content per serving (164.7 and 147.1 mg, respectively) compared with red wine and cranberry juice (22.0 and 31.9 mg, respectively). However, the procyanidin content varied greatly between apple samples (12.3-252.4 mg/serving) with the highest amounts on average observed for the Red Delicious (207.7 mg/serving) and Granny Smith (183.3 mg/serving) varieties and the lowest amounts in the Golden Delicious (92.5 mg/serving) and McIntosh (105.0 mg/serving) varieties. The compositional data reported herein are important for the initial understanding of which foods contribute most to the dietary intake of procyanidins and may be used to compile a database necessary to infer epidemiological relationships to health and disease.
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In thirty-one carbohydrate-intolerant patients, phlebotomy-induced iron depletion to near-deficiency levels was associated with reductions in several cardiovascular risk factors and in fibrinogen.
“In a small study with thirty-one carbohydrate-intolerant patients, quantitative phlebotomy was used to induce Fe depletion to near-deficiency levels (715) .The induced Fe deficiency was associated with reductions in several CVD risk factors as well as in the inflammatory marker fibrinogen.”
From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [715]
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Cites
Structure-antioxidant activity relationships of flavonoids and phenolic acids
Rice-Evans, C. A., Miller, N. J., & Paganga, G. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(95)02227-9 · Cited by 9,085 · see citing works
Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study
Hertog, M. G. L., Feskens, E. J. M., Kromhout, D., Hertog, M. G. L., Hollman, P. C. H., Hertog, M. G. L., & Katan, M. (1993) · The Lancet · doi:10.1016/0140-6736(93)92876-u · Cited by 4,336 · see citing works
High Molecular Weight Plant Polyphenolics (Tannins) as Biological Antioxidants
Hagerman, A. E., Riedl, K. M., Jones, G. A., Sovik, K. N., Ritchard, N. T., Hartzfeld, P. W., & Riechel, T. L. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf970975b · Cited by 1,386 · see citing works
Hertog, M. G. L., Hollman, P. C. H., & Katan, M. (1992) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00024a011 · Cited by 1,381 · see citing works
Frankel, E. N., Waterhouse, A. L., & Teissèdre, P. (1995) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00052a008 · Cited by 873 · see citing works
Packer, L., Rimbach, G., & Virgili, F. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00090-8 · Cited by 660 · see citing works
Rimm, E. B., Katan, M. B., Ascherio, A., Stampfer, M. J., & Willett, W. C. (1996) · Annals of Internal Medicine · doi:10.7326/0003-4819-125-5-199609010-00005 · Cited by 560 · see citing works
Hammerstone, J. F., Lazarus, S. A., Mitchell, A. E., Rucker, R., & Schmitz, H. H. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf980760h · Cited by 455 · see citing works
Self-citationDietary Flavonoid Intake and Risk of Cardiovascular Disease in Postmenopausal Women
Yochum, L., Kushi, L. H., Meyer, K., & Folsom, A. R. (1999) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009738 · Cited by 436 · see citing works
Adamson, G. E., Lazarus, S. A., Mitchell, A. E., Prior, R. L., Cao, G., Jacobs, P. H., Kremers, B. G., Hammerstone, J. F., Rucker, R. B., Ritter, K. A., et al. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf990317m · Cited by 404 · see citing works
Self-citationCocoa inhibits platelet activation and function
Rein, D., Paglieroni, T. G., Wun, T., Pearson, D. A., Schmitz, H. H., Gosselin, R. C., & Keen, C. L. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.1.30 · Cited by 359 · see citing works
Self-citationPolyphenol Profiles of French Cider Apple Varieties ( Malus domestica sp.)
Sanoner, P., Guyot, S., Marnet, N., Mollé, D., & Drilleau, J.-F. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf990563y · Cited by 324 · see citing works
Guyot, S., Marnet, N., Laraba, D., Sanoner, P., & Drilleau, J. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf970832p · Cited by 312 · see citing works
Lazarus, S. A., Adamson, G. E., Hammerstone, J. F., & Schmitz, H. H. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9813642 · Cited by 263 · see citing works
Self-citation(‐)‐Epicatechin Content in Fermented and Unfermented Cocoa Beans
KIM, H., & Keeney, P. G. (1984) · Journal of Food Science · doi:10.1111/j.1365-2621.1984.tb10400.x · Cited by 216 · see citing works
Sanbongi, C., Suzuki, N., & Sakane, T. (1997) · Cellular Immunology · doi:10.1006/cimm.1997.1109 · Cited by 210 · see citing works
Chocolate as a source of tea flavonoids
Arts, I. C. W., Hollman, P. C. H., & Kromhout, D. (1999) · The Lancet · doi:10.1016/s0140-6736(99)02267-9 · Cited by 184 · see citing works
Protection against peroxynitrite by cocoa polyphenol oligomers
Arteel, G. E., & Sies, H. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01498-2 · Cited by 163 · see citing works
Cacao procyanidins: major flavanoids and identification of some minor metabolites
Porter, L. J., Ma, Z., & Chan, B. G. (1991) · Phytochemistry · doi:10.1016/0031-9422(91)84228-k · Cited by 158 · see citing works
Bronner, W. E., & Beecher, G. R. (1998) · Journal of Chromatography A · doi:10.1016/s0021-9673(98)00040-5 · Cited by 154 · see citing works
Ariga, T., & Hamano, M. (1990) · Agricultural and Biological Chemistry · doi:10.1080/00021369.1990.10870369 · Cited by 123 · see citing works
Levels of Flavan-3-ols in French Wines
Carando, S., Teissèdre, P., Pascual-Martinez, L., et al. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9810564 · Cited by 117 · see citing works
Wine phenolics—analysis of low molecular weight components by high performance liquid chromatography
Salagoïty‐Auguste, M., & Bertrand, A. (1984) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.2740351116 · Cited by 107 · see citing works
The Antioxidative Substances in Cacao Liquor.
Osakabe, N., Yamagishi, M., Sanbongi, C., Natsume, M., Takizawa, T., & Osawa, T. (1998) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.44.313 · Cited by 90 · see citing works
Kovač, V., Alonso, E., Bourzeix, M., et al. (1992) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00022a045 · Cited by 74 · see citing works
Chocolate contains additional flavonoids not found in tea
Lazarus, S. A., Hammerstone, J. F., & Schmitz, H. H. (1999) · The Lancet · doi:10.1016/s0140-6736(05)70599-7 · Cited by 58 · see citing works
Self-citationHigh‐pressure liquid chromatography of apple juice phenolic compounds
Wilson, E. L. (1981) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.2740320309 · Cited by 56 · see citing works
Potential Cardiovascular Health Benefits of Procyanidins Present in Chocolate and Cocoa
Bearden, M. M., Pearson, D. A., Rein, D., et al. (2000) · ACS symposium series · doi:10.1021/bk-2000-0754.ch019 · Cited by 34 · see citing works
Changes and Metabolism of Phenolic Compounds in Fruits
Macheix, J., Fleuriet, A., & Billot, J. (2018) · CRC Press eBooks · doi:10.1201/9781351072175-3 · Cited by 12 · see citing works
HPLC-MS Analysis of Flavonoids in Foods and Beverages
Hammerstone, J. F., & Lazarus, S. A. (2000) · ACS symposium series · doi:10.1021/bk-2000-0754.ch038 · Cited by 8 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 3
- Clapperton, J., Hammerstone, J.F., Romanczyk, L. J., Yow, S., Lim, D. & Lock- wood, R. (1992) Polyphenols and Cocoa Flavour. Proceedings of the 16th International Conference of Groupe Polyphenols: Lisbon, Portugal, Groupe Polyphenols, Norbonne, France, Tome II: 112-115.
- Haslam, E. (1998) Polyphenols: structure and biosynthesis. In: Practical Poly- phenolics From Structure to Molecular Recognition and Physiological Action (Haslam, E., ed.), pp. 10 -83, Cambridge University Press, Cambridge, U.K.
- Waterhouse, A. L. & Walzem, R. L. (1998) Nutrition of grape phenolics. In: Flavonoids in Health and Disease (Rice-Evans, C. A. & Packer, L., eds.), pp. 359 -385, Marcel Dekker, New York, NY.
Cited by
Sorted by citations
Dietary Intake and Bioavailability of Polyphenols
Scalbert, A., & Williamson, G. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.8.2073s · Cited by 3,658 · see citing works
Dietary factors and low-grade inflammation in relation to overweight and obesity
Calder, P. C., Ahluwalia, N., Brouns, F., Buetler, T., Clement, K., Cunningham, K., Esposito, K., Jönsson, L. S., Kolb, H., Lansink, M., et al. (2011) · British Journal of Nutrition · doi:10.1017/s0007114511005460 · Cited by 1,098 · see citing works
Sorghum phytochemicals and their potential impact on human health
Awika, J. M., & Rooney, L. W. (2004) · Phytochemistry · doi:10.1016/j.phytochem.2004.04.001 · Cited by 966 · see citing works
Tannins: Current knowledge of food sources, intake, bioavailability and biological effects
Serrano, J., Puupponen‐Pimiä, R., Dauer, A., Aura, A., & Saura‐Calixto, F. (2009) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200900039 · Cited by 810 · see citing works
Anderson, R. A., Broadhurst, C. L., Polansky, M. M., Schmidt, W. F., Khan, A., Flanagan, V. P., Schoene, N. W., & Graves, D. J. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf034916b · Cited by 561 · see citing works
Grassi, D., Necozione, S., Lippi, C., Croce, G., Valeri, L., Pasqualetti, P., Desideri, G., Blumberg, J. B., & Ferri, C. (2005) · Hypertension · doi:10.1161/01.hyp.0000174990.46027.70 · Cited by 546 · see citing works
Heinrich, U., Neukam, K., Tronnier, H., Sies, H., & Stahl, W. (2006) · The Journal of Nutrition · doi:10.1093/jn/136.6.1565 · Cited by 191 · see citing works
Bayard, V., Chamorro, F., Motta, J., & Hollenberg, N. K. (2007) · International Journal of Medical Sciences · doi:10.7150/ijms.4.53 · Cited by 147 · see citing works
Flavonoids: A Myth or a Reality for Cancer Therapy?
Forni, C., Rossi, M., Borromeo, I., Feriotto, G., Platamone, G., Tabolacci, C., Mischiati, C., & Beninati, S. (2021) · Molecules · doi:10.3390/molecules26123583 · Cited by 79 · see citing works
- Authors
- Hammerstone, J. F., Lazarus, S. A., & Schmitz, H. H.
- Corresponding author
- Lazarus, Sheryl A.
- ORCID
- Schmitz, Harold H.
- Venue
- The Journal of Nutrition
- Publisher
- Elsevier BV
- Published
- 2000-08
- Volume
- 130
- Issue
- 8
- Pages
- 2086S-2092S
- ISSN
- 0022-3166 (ISSN-L)
- OpenAlex
- W2165037895
- Cited by
- 356
- References
- 30
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 6 · 2023: 9 · 2022: 5 · 2021: 10 · 2020: 8 · 2019: 13 · 2018: 14 · 2017: 11 · 2016: 12 · 2015: 15 · 2014: 18 · 2013: 20 · 2012: 20
- FWCI
- 10.45
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food and Agricultural Sciences
- Keywords
- procyanidins, flavonoids, dietary intake, apple cultivars, red wine, chocolate, cranberry juice, Red Delicious, Granny Smith, Golden Delicious, McIntosh, food composition
- MeSH terms
- Cacao, Catechin, Chromatography, High Pressure Liquid, Diet, Food Analysis, Fruit, Wine, Proanthocyanidins, Biflavonoids
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