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Photobiology of vitamins

Lucock, Mark, Jones, Patrice, Martin, Charlotte, Yates, Zoe, Veysey, Martin, Furst, John, Beckett, Emma·2018·Nutrition Reviews
DOI 10.1093/nutrit/nuy013
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Abstract

This review explores contemporary ideas about the relationship between light exposure and vitamin biology. Nutritional biochemistry has long recognized the relationship between vitamins A and D and light exposure, but in recent years other vitamins have also been implicated in photoresponsive biological mechanisms that influence health, well-being, and even evolutionary processes. Interactions between light and vitamins can modify genotype-phenotype relationships across the life cycle, providing a basis for interesting new explanations relevant to wide aspects of human biology. This review examines both well-established and emerging ideas about vitamin photobiology in the context of the following: (1) light responsiveness of vitamin D (photosynthesized in skin), vitamin A (linked to vision), and vitamin B3 (needed to repair genomic damage); (2) vulnerability of folate and vitamins B1, B2, B12, and D to ultraviolet (UV) light (all potentially degraded); (3) protective/filtering actions of carotenoids and vitamins C and E, which act as antioxidants and/or natural sunscreens, against UV light; (4) role of folate, carotenoids, and vitamins A, B3, C, D, and E in UV-related genomic regulation, maintenance, and repair; (5) role of folate and vitamins A, B2, B12, and D in a range of light-signaling and light-transduction pathways; and (6) links between folate and vitamin D and the evolution of UV light-adaptive phenotypes.

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Metadata

Authors
Lucock, M., Jones, P., Martin, C., Yates, Z., Veysey, M., Furst, J., & Beckett, E.
Affiliations
  • School of Environmental & Life Sciences, University of Newcastle, New South Wales, Australia
  • School of Biomedical Sciences & Pharmacy, University of Newcastle, New South Wales, Australia
  • Hull-York Medical School, University of York, Heslington, York, United Kingdom
  • School of Mathematical & Physical Sciences, University of Newcastle, Ourimbah, New South Wales, Australia
Venue
Nutrition Reviews
Publisher
Oxford University Press (OUP)
Published
2018-04-28
Volume
76
Issue
7
Pages
512-525
ISSN
  • 0029-6643
  • 1753-4887
DOI
10.1093/nutrit/nuy013
Cited by
17
References
12
Language
en
Licence
academic.oup.com/journals/pages/about_us/legal/notices (vor)

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