Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration

The importance of selenium to human health

Rayman, M. P. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02490-9 · Cited by 4,163 · see citing works

Characterization of Mammalian Selenoproteomes

Kryukov, G. V., Castellano, S., Novoselov, S. V., Lobanov, A. V., Zehtab, O., Guigó, R., & Gladyshev, V. N. (2003) · Science · doi:10.1126/science.1083516 · Cited by 2,353 · see citing works

Cortical inhibitory neurons and schizophrenia

Lewis, D. A., Hashimoto, T., & Volk, D. W. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1648 · Cited by 2,297 · see citing works

Oxidative stress in neurodegeneration: Cause or consequence?

Andersen, J. K. (2004) · Nature Medicine · doi:10.1038/nrn1434 · Cited by 1,869 · see citing works

SELENIUM AS AN INTEGRAL PART OF FACTOR 3 AGAINST DIETARY NECROTIC LIVER DEGENERATION

Schwarz, K., & Foltz, C. M. (1957) · Journal of the American Chemical Society · doi:10.1021/ja01569a087 · Cited by 1,850 · see citing works

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

Seiler, A., Schneider, M., Förster, H., Roth, S., Wirth, E. K., Culmsee, C., Plesnila, N., Kremmer, E., Rådmark, O., Wurst, W., et al. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.07.005 · Cited by 1,470 · see citing works

BDNF Regulates the Maturation of Inhibition and the Critical Period of Plasticity in Mouse Visual Cortex

Huang, Z. J., Kirkwood, A., Pizzorusso, T., Porciatti, V., Morales, B., Bear, M. F., Maffei, L., & Tonegawa, S. (1999) · Cell · doi:10.1016/s0092-8674(00)81509-3 · Cited by 1,198 · see citing works

The origin and specification of cortical interneurons

Wonders, C. P., & Anderson, S. A. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1954 · Cited by 980 · see citing works

Cholinergic induction of network oscillations at 40 Hz in the hippocampus in vitro

Fisahn, A., Pike, F. G., Buhl, E. H., & Paulsen, O. (1998) · Nature · doi:10.1038/28179 · Cited by 884 · see citing works

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

Yant, L. J., Ran, Q., Rao, L., Van Remmen, H., Shibatani, T., Belter, J. G., Motta, L., Richardson, A., & Prolla, T. A. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01360-6 · Cited by 797 · see citing works

How Selenium Has Altered Our Understanding of the Genetic Code

Hatfield, D. L., & Gladyshev, V. N. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.11.3565-3576.2002 · Cited by 681 · see citing works

Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis.

Burk, R. F., & Hill, K. (2005) · Annual review of nutrition · doi:10.1146/annurev.nutr.24.012003.132120 · Cited by 591 · see citing works

Ketamine-Induced Loss of Phenotype of Fast-Spiking Interneurons Is Mediated by NADPH-Oxidase

Behrens, M. M., Ali, S. S., Dao, D. N., Lucero, J., Shekhtman, G., Quick, K. L., & Dugan, L. L. (2007) · Science · doi:10.1126/science.1148045 · Cited by 585 · see citing works

Deletion of Selenoprotein P Alters Distribution of Selenium in the Mouse*

Hill, K., Zhou, J.-D., McMahan, W. J., Motley, A., Atkins, J., Gesteland, R., & Burk, R. F. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300755200 · Cited by 469 · see citing works

Evidence for specific selenium target tissues and new biologically important selenoproteins

BEHNE, D., Hilmert, H., Scheid, S., Gessner, H., & Elger, W. A. G. (1988) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(88)90123-7 · Cited by 466 · see citing works

Sirt1 contributes critically to the redox-dependent fate of neural progenitors

Prozorovski, T., Schulze-Topphoff, U., Glumm, R., Baumgart, J., Schröter, F., Ninnemann, O., Siegert, E., Bendix, I., Brüstle, O., Nitsch, R., et al. (2008) · Nature Cell Biology · doi:10.1038/ncb1700 · Cited by 451 · see citing works

Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues

Schomburg, L., Schweizer, U., Holtmann, B., Flohé, L., Sendtner, M., & Köhrle, J. (2003) · Biochemical Journal · doi:10.1042/bj20021853 · Cited by 423 · see citing works

Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell

Smith, J., Ladi, E., Mayer-Pröschel, M., & Noble, M. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.170209797 · Cited by 399 · see citing works

Survival and growth of hippocampal neurons in defined medium at low density: advantages of a sandwich culture technique or low oxygen

Brewer, G. J., & Cotman, C. W. (1989) · Brain Research · doi:10.1016/0006-8993(89)90144-3 · Cited by 376 · see citing works

Selenium and brain function: a poorly recognized liaison

Schweizer, U., Bräuer, A. U., Köhrle, J., Nitsch, R., & Savaskan, N. E. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.03.004 · Cited by 347 · see citing works

The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes

Butt, S. J. B., Sousa, V. H., Fuccillo, M. V., Hjerling-Leffler, J., Miyoshi, G., Kimura, S., & Fishell, G. (2008) · Neuron · doi:10.1016/j.neuron.2008.07.031 · Cited by 330 · see citing works

A Specific Role for NR2A-Containing NMDA Receptors in the Maintenance of Parvalbumin and GAD67 Immunoreactivity in Cultured Interneurons

Kinney, J. W., Davis, C. N., Tabarean, I., Conti, B., Bartfai, T., & Behrens, M. M. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4722-05.2006 · Cited by 329 · see citing works

Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence

Gysin, R., Kraftsik, R., Sandell, J., Bovet, P., Chappuis, C., Conus, P., Deppen, P., Preisig, M., Ruiz, V., Steullet, P., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706778104 · Cited by 309 · see citing works

A CamKIIα iCre BAC allows brain‐specific gene inactivation

Casanova, E., Fehsenfeld, S., Mantamadiotis, T., Lemberger, T., Greiner, E. F., Stewart, A. F., & Schütz, G. (2001) · genesis · doi:10.1002/gene.1078 · Cited by 293 · see citing works

Apolipoprotein E Receptor-2 (ApoER2) Mediates Selenium Uptake from Selenoprotein P by the Mouse Testis

Olson, G. E., Winfrey, V. P., Nagdas, S. K., Hill, K. E., & Burk, R. F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611403200 · Cited by 246 · see citing works

Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supply

Schweizer, U., Streckfuß, F., Pelt, P., Carlson, B. A., Hatfield, D. L., Köhrle, J., & Schomburg, L. (2005) · Biochemical Journal · doi:10.1042/bj20041973 · Cited by 207 · see citing works

Neuronal 3′,3,5-Triiodothyronine (T 3 ) Uptake and Behavioral Phenotype of Mice Deficient in Mct8 , the Neuronal T 3 Transporter Mutated in Allan–Herndon–Dudley Syndrome

Wirth, E. K., Roth, S., Blechschmidt, C., Hölter, S. M., Becker, L., Rácz, I., Zimmer, A., Klopstock, T., Gailus‐Durner, V., Fuchs, H., et al. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.6055-08.2009 · Cited by 193 · see citing works

Neurological Dysfunction Occurs in Mice with Targeted Deletion of the Selenoprotein P Gene

Hill, K. E., McMahan, W. J., Motley, A. K., Burk, R. F., & Zhou, J. (2004) · Journal of Nutrition · doi:10.1093/jn/134.1.157 · Cited by 184 · see citing works

Deletion of Apolipoprotein E Receptor-2 in Mice Lowers Brain Selenium and Causes Severe Neurological Dysfunction and Death When a Low-Selenium Diet Is Fed

Burk, R. F., Hill, K. E., Olson, G. E., Weeber, E. J., Motley, A. K., Winfrey, V. P., & Austin, L. M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1153-07.2007 · Cited by 181 · see citing works

Comparative Analysis of Selenocysteine Machinery and Selenoproteome Gene Expression in Mouse Brain Identifies Neurons as Key Functional Sites of Selenium in Mammals

Zhang, Y., Zhou, Y., Schweizer, U., Savaskan, N. E., Hua, D., Kipnis, J., Hatfield, D. L., & Gladyshev, V. N. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m707951200 · Cited by 178 · see citing works

Selenium Deficiency Triggering Intractable Seizures

Ramaekers, V. T., Calomme, M. R., Berghe, D. V., et al. (1994) · Neuropediatrics · doi:10.1055/s-2008-1073025 · Cited by 146 · see citing works

Thyroid Hormone Insufficiency during Brain Development Reduces Parvalbumin Immunoreactivity and Inhibitory Function in the Hippocampus

Gilbert, M. E., Sui, L., Walker, M. J., Anderson, W. L., Thomas, S., Smoller, S. N., Schon, J. P., Phani, S., & Goodman, J. H. (2006) · Endocrinology · doi:10.1210/en.2006-0164 · Cited by 144 · see citing works

Glutathione peroxidase deficiency and childhood seizures

Weber, G. F., Maertens, P. M., Xu, M., & Pippenger, C. E. (1991) · The Lancet · doi:10.1016/0140-6736(91)93130-2 · Cited by 126 · see citing works

The Role of Thioredoxin Reductases in Brain Development

Soerensen, J., Jakupoglu, C., Beck, H., Förster, H., Schmidt, J., Schmahl, W., Schweizer, U., Conrad, M., & Brielmeier, M. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001813 · Cited by 114 · see citing works

Serum Factor Supporting Long-Rerm Survival of Rat Central Neurons in Culture

Kaufman, L. M., & Barrett, J. N. (1983) · Science · doi:10.1126/science.6857258 · Cited by 113 · see citing works

Locomotor Deficiencies and Aberrant Development of Subtype-Specific GABAergic Interneurons Caused by an Unliganded Thyroid Hormone Receptor α1

Wallis, K., Sjögren, M., van Hogerlinden, M., Silberberg, G., Fisahn, A., Nordström, K., Larsson, L., Westerblad, H., de Escobar, G. M., Shupliakov, O., et al. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5163-07.2008 · Cited by 113 · see citing works

α 1E -Containing Ca 2+ channels are involved in synaptic plasticity

Breustedt, J., Vogt, K. E., Miller, R. J., Nicoll, R. A., & Schmitz, D. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2035117100 · Cited by 113 · see citing works

Purification from Bovine Serum of a Survival-Promoting Factor for Cultured Central Neurons and Its Identification as Selenoprotein-P

Yan, J., & Barrett, J. N. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-21-08682.1998 · Cited by 107 · see citing works

Efficient selenium transfer from mother to offspring in selenoprotein-P-deficient mice enables dose-dependent rescue of phenotypes associated with selenium deficiency

Schweizer, U., Michaelis, M., Köhrle, J., et al. (2004) · Biochemical Journal · doi:10.1042/bj20031795 · Cited by 106 · see citing works

Selective Removal of the Selenocysteine tRNA[Ser]Sec Gene (Trsp) in Mouse Mammary Epithelium

Kumaraswamy, E., Carlson, B. A., Morgan, F., Miyoshi, K., Robinson, G. W., Su, D., Wang, S., Southon, E. A., Tessarollo, L., Lee, B. J., et al. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.5.1477-1488.2003 · Cited by 106 · see citing works

The Neurobiology of Selenium: Lessons from Transgenic Mice

Schweizer, U., Schomburg, L., & Savaskan, N. E. (2004) · Journal of Nutrition · doi:10.1093/jn/134.4.707 · Cited by 100 · see citing works

Neuronal and ependymal expression of selenoprotein P in the human brain

Scharpf, M. O., Schweizer, U., Arzberger, T., Roggendorf, W., Schomburg, L., & Köhrle, J. (2007) · Journal of Neural Transmission · doi:10.1007/s00702-006-0617-0 · Cited by 91 · see citing works

Neurodegeneration in Mice Resulting From Loss of Functional Selenoprotein P or Its Receptor Apolipoprotein E Receptor 2

Valentine, W. M., Abel, T. W., Hill, K. E., Austin, L. M., & Burk, R. F. (2008) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e318160f347 · Cited by 91 · see citing works

Ablation of TrkA function in the immune system causes B cell abnormalities

Coppola, V., Barrick, C. A., Southon, E. A., Celeste, A., Wang, K., Chen, B., Haddad, E., Yin, J. L., Nussenzweig, A., Subramaniam, A., et al. (2004) · Development · doi:10.1242/dev.01383 · Cited by 66 · see citing works

The selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice

Carlson, B. A., Schweizer, U., Perella, C. M., Shrimali, R. K., Feigenbaum, L., Shen, L., Speransky, S. R., Floß, T., Jeong, S.-J., Watts, J. C., et al. (2008) · Biochemical Journal · doi:10.1042/bj20081304 · Cited by 38 · see citing works

Podocyte specific knock out of selenoproteins does not enhance nephropathy in streptozotocin diabetic C57BL/6 mice

Blauwkamp, M., Yu, J., Schin, M., et al. (2008) · BMC Nephrology · doi:10.1186/1471-2369-9-7 · Cited by 20 · see citing works

Role of GPX4 in ferroptosis and its pharmacological implication

Seibt, T. M., Proneth, B., & Conrad, M. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.09.014 · Cited by 1,520 · see citing works

Ferroptosis: Role of lipid peroxidation, iron and ferritinophagy

Latunde-Dada, G. O. (2017) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2017.05.019 · Cited by 892 · see citing works

Ferroptosis Inhibition: Mechanisms and Opportunities

Angeli, J. P. F., Shah, R., Pratt, D. A., & Conrad, M. (2017) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2017.02.005 · Cited by 563 · see citing works

Regulation of lipid peroxidation and ferroptosis in diverse species

Conrad, M., Kagan, V. E., Bayir, H., Pagnussat, G. C., Head, B., Traber, M. G., & Stockwell, B. R. (2018) · Genes & Development · doi:10.1101/gad.314674.118 · Cited by 544 · see citing works

Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration

Carlson, B. A., Tobe, R., Yefremova, E., Tsuji, P. A., Hoffmann, V. J., Schweizer, U., Gladyshev, V. N., Hatfield, D. L., & Conrad, M. (2016) · Redox Biology · doi:10.1016/j.redox.2016.05.003 · Cited by 316 · see citing works

Linking early-life NMDAR hypofunction and oxidative stress in schizophrenia pathogenesis

Hardingham, G. E., & Do, K. Q. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2015.19 · Cited by 304 · see citing works

Deletion of selenoprotein P results in impaired function of parvalbumin interneurons and alterations in fear learning and sensorimotor gating

Pitts, M. W., Raman, A. V., Hashimoto, A. C., Todorovic, C., Nichols, R. A., & Berry, M. J. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.02.017 · Cited by 67 · see citing works

How Nox2-Containing NADPH Oxidase Affects Cortical Circuits in the NMDA Receptor Antagonist Model of Schizophrenia

Wang, X., Pinto-Duarte, A., Sejnowski, T. J., & Behrens, M. M. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4907 · Cited by 46 · see citing works

Development and specification of GABAergic cortical interneurons

Kelsom, C., & Lu, W. (2013) · Cell & Bioscience · doi:10.1186/2045-3701-3-19 · Cited by 171 · see citing works

Inhibitory circuits of the mammalian main olfactory bulb

Burton, S. D. (2017) · Journal of Neurophysiology · doi:10.1152/jn.00109.2017 · Cited by 124 · see citing works

Cortical control of chandelier cells in neural codes

Jung, K., Choi, Y., & Kwon, H. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.992409 · Cited by 11 · see citing works

A role for GABAergic interneuron diversity in circuit development and plasticity of the neonatal cerebral cortex

Butt, S. J. B., Stacey, J. A., Teramoto, Y., & Vagnoni, C. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.03.011 · Cited by 61 · see citing works

The Origins and Specification of Cortical Interneurons

Maroof, A. M., & Anderson, S. A. (2009) · Springer eBooks · doi:10.1007/978-1-4419-1243-5_2 · Cited by 2 · see citing works