Early visual cortex organization in autism: an fMRI study
Abstract
Autism is a neurodevelopmental disorder characterized by preserved visual abilities as well as a special profile for visual cognition. We examined the visual cortex of high-ability individuals with autism in order to assess whether the presence of abnormalities at the primary sensory level in autism could be the basis of their unusual pattern of visual cognitive abilities. We found that the early sensory visual areas are normally organized in individuals with autism, with a normal ratio between central versus peripheral visual field representation. We conclude that the differences observed in the visual capacities of individuals with autism are likely to arise from higher-level cognitive areas and functions, and are the result of top-down processes.
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Individuals with autism spectrum disorder appear very similar to typically developing individuals in the basic organization of visual space in visual cortex.
“In terms of basic organization of visual space (ratio of central vs. peripheral representation) in the visual cortex, individuals with ASD appear very similar to individuals with TD (Hadjikhani et al., 2004).”
From Behavioral, Perceptual, and Neural Alterations in Sensory and Multisensory Function in Autism Spectrum Disorder (2015) · cites this paper as Hadjikhani et al., 2004
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- Authors
- Hadjikhani, N., Chabris, C. F., Joseph, R. M., Clark, J., McGrath, L., Aharon, I., Feczko, E., Tager-Flusberg, H., & Harris, G. J.
- Affiliations
- Harvard University (US)
- Boston University (US)
- ORCID
- Venue
- Neuroreport
- Published
- 2004-02
- Volume
- 15
- Issue
- 2
- Pages
- 267-270
- ISSN
- 0959-4965 (ISSN-L)
- OpenAlex
- W1971046263
- Cited by
- 57
- References
- 28
- Citations by year
- 2024: 1 · 2022: 1 · 2021: 2 · 2020: 5 · 2019: 3 · 2018: 1 · 2017: 2 · 2016: 1 · 2015: 3 · 2014: 3 · 2013: 3 · 2012: 4
- FWCI
- 2.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroreport (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Deafness and Other Communication Disorders (DC03610)
- National Institute of Neurological Disorders and Stroke (R01 NS 44824-01, R01NS044824)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
- Keywords
- autism spectrum disorder, visual cortex, primary visual cortex, visual field representation, visual cognition, top-down processing, high-functioning autism, neurodevelopmental disorders
- MeSH terms
- Adolescent, Adult, Attention, Autistic Disorder, Brain Mapping, Cerebral Cortex, Cognition, Humans, Functional Laterality, Magnetic Resonance Imaging, Middle Aged, Neural Pathways, Photic Stimulation, Reference Values, Visual Cortex, Visual Fields, Visual Perception
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