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Cited by 105Cardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic ControlLong-Term Effects of COVID-19

The Postural Tachycardia Syndrome

Medow, Marvin S., Stewart, Julian M.·2007·Cardiology in Review
DOI 10.1097/01.crd.0000233768.68421.40
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Abstract

Postural tachycardia syndrome (POTS) is a disorder of unknown etiology, and patients with this condition exhibit orthostatic intolerance (OI) and excessive tachycardia. Excessive tachycardia with POTS has been defined as a rapid (within 10 minutes) increase in heart rate by more than 30 beats per minute or a heart rate that exceeds 120 beats per minute. Patients with POTS can experience difficulty with daily routines such as housework, shopping, eating, and attending work or school. The possibility exists that all forms of OI, including POTS, result from central hypovolemia even without tachycardia. The clinical findings of POTS are observed in an increasing number of patients who are usually female and aged 15 to 50 years. Adults with POTS do not have hypotension, whereas children may exhibit hypotension. Many patients with POTS are intolerant of exercise. "Idiopathic" POTS must be distinguished from other conditions that can reduce venous return to the heart and produce similar signs and symptoms such as dehydration, anemia, or hyperthyroidism. Therapies for POTS are directed at relieving the central hypovolemia or at compensating for the circulatory dysfunctions that may cause this disorder. Treatments have resulted in varying degrees of success and are often used in combination with each other.

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Crossref · 10.1097/01.crd.0000233768.68421.40

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  • Excessive tachycardia in POTS occurs during exercise as well as standing, and patients experience significant exercise intolerance.

    “Excessive tachycardia in POTS occurs during exercise as well as during standing [60;61], and patients experience significant exercise intolerance [9;19].”

    From Postural tachycardia syndrome: beyond orthostatic intolerance (2015) · cites this paper as [9]

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Authors
Medow, M. S., & Stewart, J. M.
Affiliations
New York Medical College (US)
Corresponding author
Medow, Marvin S.
ORCID
Venue
Cardiology in Review
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2007-03
Volume
15
Issue
2
Pages
67-75
ISSN
1061-5377 (ISSN-L)
DOI
10.1097/01.crd.0000233768.68421.40
OpenAlex
W2034959806
Cited by
105
References
80
Citations by year
2026: 3 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 4 · 2021: 2 · 2020: 3 · 2019: 9 · 2018: 6 · 2017: 3 · 2016: 12 · 2015: 3 · 2014: 13 · 2013: 8 · 2012: 8
FWCI
0.99
Type
journal article
Language
en
Open access
closed
Locations
  • Cardiology in Review (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
Keywords
postural orthostatic tachycardia syndrome, orthostatic intolerance, central hypovolemia, tachycardia, venous return, exercise intolerance, differential diagnosis, autonomic dysfunction
MeSH terms
Adolescent, Adult, Cardiovascular Agents, Exercise Therapy, Female, Humans, Hypotension, Orthostatic, Infusions, Intravenous, Male, Middle Aged, Regional Blood Flow, Sodium Chloride, Syndrome, Tachycardia, Age Distribution, Sex Distribution

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