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Cited by 350Enhanced Recovery After SurgeryClinical Nutrition and GastroenterologyHyperglycemia and glycemic control in critically ill and hospitalized patients

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Promoting Perioperative Metabolic and Nutritional Care

Gillis, Chelsia, Carli, Francesco·2015·Anesthesiology
DOI 10.1097/aln.0000000000000795
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Abstract

AbstractAbstract: Surgery represents a major stressor that disrupts homeostasis and can lead to loss of body cell mass. Integrated, multidisciplinary medical strategies, including enhanced recovery programs and perioperative nutrition support, can mitigate the surgically induced metabolic response, promoting optimal patient recovery following major surgery. Clinical therapies should identify those who are poorly nourished before surgery and aim to attenuate catabolism while preserving the processes that promote recovery and immunoprotection after surgery. This review will address the impact of surgery on intermediary metabolism and describe the clinical consequences that ensue. It will also focus on the role of perioperative nutrition, including preoperative nutrition risk, carbohydrate loading, and early initiation of oral feeding (centered on macronutrients) in modulating surgical stress, as well as highlight the contribution of the anesthesiologist to nutritional care. Emerging therapeutic concepts such as preoperative glycemic control and prehabilitation will be discussed. This article is a narrative review that focuses on the role of perioperative nutrition in modulating the surgical stress response, as well as the contribution of the anesthesiologist to nutritional care. Preoperative nutrition risk, carbohydrate loading, early initiation of oral feeding, anesthetic strategies to facilitate nutritional gains, preoperative glycemic control, and prehabilitation will be addressed.

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Cites

Research works printed but not linked: 161

  1. 2001, Risk factors for malnutrition in patients undergoing gastroenterological and hernia surgery: An analysis of 374 patients., Nutr Hosp, 16, 59
  2. 1995, Preoperative nutritional status and prognostic nutritional index in patients with benign disease undergoing abdominal operations—Part I., J Am Coll Nutr, 14, 80, 10.1080/07315724.1995.10718477 · DOI
  3. 2007, Who benefits from nutritional support: What is the evidence?, Eur J Gastroenterol Hepatol, 19, 353, 10.1097/MEG.0b013e32801055c0 · DOI
  4. 2012, Impact of preoperative nutritional support on clinical outcome in abdominal surgical patients at nutritional risk., Nutrition, 28, 1022, 10.1016/j.nut.2012.01.017 · DOI
  5. 2010, Nutritional status, nutrition practices and post-operative complications in patients with gastrointestinal cancer., J Hum Nutr Diet, 23, 393, 10.1111/j.1365-277X.2010.01058.x · DOI
  6. 2009, The correlation of nutrition risk index, nutrition risk score, and bioimpedance analysis with postoperative complications in patients undergoing gastrointestinal surgery., Surgery, 145, 519, 10.1016/j.surg.2009.02.001 · DOI
  7. 2013, Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations., World J Surg, 37, 259, 10.1007/s00268-012-1772-0 · DOI
  8. 2002, From Cuthbertson to fast-track surgery: 70 years of progress in reducing stress in surgical patients., Ann Surg, 236, 643, 10.1097/00000658-200211000-00015 · DOI
  9. 2002, Epidural anaesthesia and analgesia—Effects on surgical stress responses and implications for postoperative nutrition., Clin Nutr, 21, 199, 10.1054/clnu.2001.0514 · DOI
  10. 2009, Stress hormones: Physiological stress and regulation of metabolism., Curr Opin Pharmacol, 9, 787, 10.1016/j.coph.2009.08.007 · DOI
  11. 1990, The metabolic response to stress: An overview and update., Anesthesiology, 73, 308, 10.1097/00000542-199008000-00020 · DOI
  12. 1989, The immune- hypothalamic-pituitary-adrenal axis., Endocr Rev, 10, 92, 10.1210/edrv-10-1-92 · DOI
  13. 2012, Neuroendocrine and immune responses to surgery., Internet J Anesthesiol, 30, 3
  14. 2000, Metabolic response to severe surgical illness: Overview., World J Surg, 24, 705, 10.1007/s002689910113 · DOI
  15. 2001, Alterations in fuel metabolism in critical illness: Hyperglycaemia., Best Pract Res Clin Endocrinol Metab, 15, 533, 10.1053/beem.2001.0168 · DOI
  16. 2009, Modulating postoperative insulin resistance by preoperative carbohydrate loading., Best Pract Res Clin Anaesthesiol, 23, 401, 10.1016/j.bpa.2009.08.004 · DOI · Paper page
  17. 1985, Assessment of alanine, urea, and glucose interrelationship in normal subjects and in patients with sepsis with stable isotope tracers., Surgery, 97, 551
  18. 2012, Jonathan E. Rhoads lecture 2011: Insulin resistance and enhanced recovery after surgery., JPEN J Parenter Enteral Nutr, 36, 389, 10.1177/0148607112445580 · DOI
  19. 1997, Site of insulin resistance after surgery: The contribution of hypocaloric nutrition and bed rest., Clin Sci (Lond), 93, 137, 10.1042/cs0930137 · DOI
  20. 1990, Insulin resistance after surgery: Normalization by insulin treatment., Clin Sci (Lond), 79, 443, 10.1042/cs0790443 · DOI
  21. 2013, Importance of perioperative glycemic control in general surgery: A report from the Surgical Care and Outcomes Assessment Program., Ann Surg, 257, 8, 10.1097/SLA.0b013e31827b6bbc · DOI · Paper page
  22. 2012, Hyperglycemia is associated with increased risk of morbidity and mortality after colectomy for cancer., J Am Coll Surg, 214, 68, 10.1016/j.jamcollsurg.2011.09.016 · DOI
  23. 2001, Intensive insulin therapy in critically ill patients., N Engl J Med, 345, 1359, 10.1056/NEJMoa011300 · DOI · Paper page
  24. 2012, Perioperative glycaemic control for diabetic patients undergoing surgery., Cochrane Database Syst Rev, 9, CD007315
  25. 2009, Peri-operative glycaemic control regimens for preventing surgical site infections in adults., Cochrane Database Syst Rev, 3, CD006806
  26. 2013, Stress hyperglycemia: An essential survival response!, Crit Care, 17, 305, 10.1186/cc12514 · DOI
  27. 2012, The evolutionary benefit of insulin resistance., Clin Nutr, 31, 1002, 10.1016/j.clnu.2012.05.011 · DOI
  28. 2005, Randomized clinical trial of the anabolic effect of hypocaloric parenteral nutrition after abdominal surgery., Br J Surg, 92, 947, 10.1002/bjs.5105 · DOI
  29. 1998, Fibrinogen synthesis is elevated in fasting cancer patients with an acute phase response., J Nutr, 128, 1355, 10.1093/jn/128.8.1355 · DOI
  30. 1980, Plasma amino acid concentrations in surgical patients., JPEN J Parenter Enteral Nutr, 4, 161, 10.1177/014860718000400218 · DOI
  31. 2004, Amino acid adequacy in pathophysiological states., J Nutr, 134, 1575
  32. 2007, Dynamics of albumin synthesis after major rectal operation., Surgery, 141, 660, 10.1016/j.surg.2006.09.018 · DOI
  33. 2013, Patient optimization for gastrointestinal cancer surgery., Br J Surg, 100, 15, 10.1002/bjs.8988 · DOI
  34. 1993, Impaired recovery of strength in older patients after major abdominal surgery., Ann Surg, 218, 380, 10.1097/00000658-199309000-00017 · DOI
  35. 1993, Metabolic basis for the management of patients undergoing major surgery., World J Surg, 17, 146, 10.1007/BF01658920 · DOI
  36. 2013, Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: A pilot study., J Cachexia Sarcopenia Muscle, 4, 71, 10.1007/s13539-012-0073-7 · DOI
  37. 2014, What does it really mean to “recover” from an operation?, Surgery, 155, 211, 10.1016/j.surg.2013.10.002 · DOI
  38. 2014, Measuring postoperative recovery: What are clinically meaningful differences?, Surgery, 156, 319, 10.1016/j.surg.2014.03.005 · DOI
  39. 2004, Functional independence after major abdominal surgery in the elderly., J Am Coll Surg, 199, 762, 10.1016/j.jamcollsurg.2004.05.280 · DOI
  40. 2013, Impact of a trimodal prehabilitation program on functional recovery after colorectal cancer surgery: A pilot study., Surg Endosc, 27, 1072, 10.1007/s00464-012-2560-5 · DOI
  41. 2000, The role of albumin in critical illness., Br J Anaesth, 85, 599, 10.1093/bja/85.4.599 · DOI
  42. 2003, Colitis increases albumin synthesis at the expense of muscle protein synthesis in macronutrient-restricted piglets., J Nutr, 133, 1875, 10.1093/jn/133.6.1875 · DOI
  43. 2008, Altered protein metabolism following coronary artery bypass graft (CABG) surgery., Clin Sci (Lond), 114, 339, 10.1042/CS20070278 · DOI
  44. 1992, Acute suppression of albumin synthesis in systemic inflammatory disease: An individually graded response of rat hepatocytes., J Histochem Cytochem, 40, 201, 10.1177/40.2.1552164 · DOI
  45. 1987, Study of the molecular mechanism of decreased liver synthesis of albumin in inflammation., J Clin Invest, 79, 1635, 10.1172/JCI113000 · DOI
  46. 2002, Albumin synthesis in humans increases immediately following the administration of endotoxin., Clin Sci (Lond), 103, 525, 10.1042/cs1030525 · DOI
  47. 1991, The independent metabolic effects of enflurane anaesthesia and surgery., Acta Anaesthesiol Scand, 35, 329, 10.1111/j.1399-6576.1991.tb03299.x · DOI
  48. 2004, The synthesis rate of albumin decreases during laparoscopic surgery., Clin Physiol Funct Imaging, 24, 91, 10.1111/j.1475-097X.2004.00535.x · DOI
  49. 2006, Serum proteins as markers of nutrition: What are we treating?, Pract Gastroenterol, 46
  50. 1980, [Behavior of non-esterified fatty acids (NEFA) after surgical operations]., Minerva Chir, 35, 929
  51. 2014, Enhanced recovery program in colorectal surgery: A meta-analysis of randomized controlled trials., World J Surg, 38, 1531, 10.1007/s00268-013-2416-8 · DOI
  52. 2013, Enhanced recovery after surgery programs versus traditional care for colorectal surgery: A meta-analysis of randomized controlled trials., Dis Colon Rectum, 56, 667, 10.1097/DCR.0b013e3182812842 · DOI
  53. 2009, An enhanced-recovery protocol improves outcome after colorectal resection already during the first year: A single-center experience in 168 consecutive patients., Dis Colon Rectum, 52, 978, 10.1007/DCR.0b013e31819f1416 · DOI
  54. 2012, Which fast track elements predict early recovery after colon cancer surgery?, Colorectal Dis, 14, 1001, 10.1111/j.1463-1318.2011.02854.x · DOI
  55. 2004, Randomized clinical trial of the effects of immediate enteral nutrition on metabolic responses to major colorectal surgery in an enhanced recovery protocol., Br J Surg, 91, 1138, 10.1002/bjs.4642 · DOI
  56. 2006, ESPEN Guidelines on Enteral Nutrition: Surgery including organ transplantation., Clin Nutr, 25, 224, 10.1016/j.clnu.2006.01.015 · DOI
  57. 2009, ESPEN guidelines on parenteral nutrition: Surgery., Clin Nutr, 28, 378, 10.1016/j.clnu.2009.04.002 · DOI
  58. 2013, Patients requiring perioperative nutritional support., Med Clin North Am, 97, 1181, 10.1016/j.mcna.2013.07.003 · DOI
  59. 2002, The immune system: A target for functional foods?, Br J Nutr, 88, S165
  60. 2003, Changes in the immune system are conditioned by nutrition., Eur J Clin Nutr, 57, S66
  61. 2007, A review of reviews: A new look at the evidence for oral nutritional supplements in clinical practice., Clin Nutr Suppl, 2, 5, 10.1016/j.clnu.2007.04.004 · DOI
  62. 2000, Impact of declines in nutritional status on outcomes in adult patients hospitalized for more than 7 days., J Am Diet Assoc, 100, 1316, 10.1016/S0002-8223(00)00373-4 · DOI
  63. 2005, Elucidating effective ways to identify and treat malnutrition., Proc Nutr Soc, 64, 305, 10.1079/PNS2005436 · DOI
  64. 2015, Nutrition adequacy in enhanced recovery after surgery: A single academic center experience., Nutr Clin Pract, 30, 414, 10.1177/0884533614562840 · DOI
  65. 2012, Risk factors for 30-day hospital readmission among general surgery patients., J Am Coll Surg, 215, 322, 10.1016/j.jamcollsurg.2012.05.024 · DOI · Paper page
  66. 2013, The anabolic effect of perioperative nutrition depends on the patient’s catabolic state before surgery., Ann Surg, 257, 155, 10.1097/SLA.0b013e31825ffc1f · DOI
  67. 2009, Influence of delays to nonemergent colon cancer surgery on operative mortality, disease-specific survival and overall survival., Can J Surg, 52, E79
  68. 2013, An evidence-based approach to perioperative nutrition support in the elective surgery patient., JPEN J Parenter Enteral Nutr, 37, 39S
  69. 2013, Summary points and consensus recommendations from the North American Surgical Nutrition Summit., JPEN J Parenter Enteral Nutr, 37, 99S
  70. 2007, Randomized clinical trial of the effect of preoperative oral carbohydrate treatment on postoperative whole-body protein and glucose kinetics., Br J Surg, 94, 1342, 10.1002/bjs.5919 · DOI
  71. 2009, The physiologic response and associated clinical benefits from provision of early enteral nutrition., Nutr Clin Pract, 24, 305, 10.1177/0884533609335176 · DOI · Paper page
  72. 2008, Anticatabolic effects of avoiding preoperative fasting by intravenous hypocaloric nutrition: A randomized clinical trial., Ann Surg, 248, 1051, 10.1097/SLA.0b013e31818842d8 · DOI
  73. 2005, Canadian Association of General Surgeons and American College of Surgeons evidence based reviews in surgery. 14. Preoperative fasting for adults to prevent perioperative complications., Can J Surg, 48, 409
  74. 2001, Preoperative nutrition—Elective surgery in the fed or the overnight fasted state., Clin Nutr, 20, 167, 10.1054/clnu.2001.0462 · DOI
  75. 2015, Preoperative oral carbohydrate therapy., Curr Opin Anaesthesiol, 28, 364, 10.1097/ACO.0000000000000192 · DOI
  76. 2014, Preoperative carbohydrate treatment for enhancing recovery after elective surgery., Cochrane Database Syst Rev, 8, CD009161
  77. 2013, Perioperative nutrition: What is the current landscape?, JPEN J Parenter Enteral Nutr, 37, 5S
  78. 2015, Single-dose carbohydrate treatment in the immediate preoperative phase diminishes development of postoperative peripheral insulin resistance., Clin Nutr, 34, 156, 10.1016/j.clnu.2014.02.010 · DOI
  79. 2011, Practice guidelines for preoperative fasting and the use of pharmacologic agents to reduce the risk of pulmonary aspiration: Application to healthy patients undergoing elective procedures: An updated report by the American Society of Anesthesiologists Committee on Standards and Practice Parameters., Anesthesiology, 114, 495, 10.1097/ALN.0b013e3181fcbfd9 · DOI
  80. 1990, Metabolic effects of reducing rate of glucose ingestion by single bolus versus continuous sipping., Diabetes, 39, 775, 10.2337/diab.39.7.775 · DOI · Paper page
  81. 1995, Preoperative gastric emptying. Effects of anxiety and oral carbohydrate administration., Ann Surg, 222, 728, 10.1097/00000658-199512000-00006 · DOI
  82. 1994, Gastric emptying of water and isocaloric carbohydrate solutions consumed at rest., Med Sci Sports Exerc, 26, 725, 10.1249/00005768-199406000-00012 · DOI
  83. 2000, Plasma insulin responses after ingestion of different amino acid or protein mixtures with carbohydrate., Am J Clin Nutr, 72, 96, 10.1093/ajcn/72.1.96 · DOI · Paper page
  84. 2011, Effects of preoperative feeding with a whey protein plus carbohydrate drink on the acute phase response and insulin resistance. A randomized trial., Nutr J, 10, 66, 10.1186/1475-2891-10-66 · DOI
  85. 2007, Parenteral nutrition and protein sparing after surgery: Do we need glucose?, Metabolism, 56, 1044, 10.1016/j.metabol.2007.03.013 · DOI
  86. 2004, Garci-Armui: Perioperative nutrition prevents the early protein losses in patients submitted to gastrointestinal surgery., Clin Nutr, 23, 1001, 10.1016/j.clnu.2003.12.006 · DOI
  87. 2006, Early enteral nutrition within 24h of colorectal surgery versus later commencement of feeding for postoperative complications., Cochrane Database Syst Rev, 18, 2
  88. 1996, Influence of postoperative enteral nutrition on postsurgical infections., Gut, 39, 833, 10.1136/gut.39.6.833 · DOI
  89. 2011, Early versus traditional postoperative feeding in patients undergoing resectional gastrointestinal surgery: A meta-analysis., JPEN J Parenter Enteral Nutr, 35, 473, 10.1177/0148607110385698 · DOI · Paper page
  90. 2001, Early enteral feeding versus “nil by mouth” after gastrointestinal surgery: Systematic review and meta-analysis of controlled trials., BMJ, 323, 773, 10.1136/bmj.323.7316.773 · DOI · Paper page
  91. 2005, Enteral feeding., Curr Opin Gastroenterol, 21, 187, 10.1097/01.mog.0000153345.57239.2c · DOI
  92. 2011, Nutrition and gut immunity., Surg Clin North Am, 91, 755, 10.1016/j.suc.2011.04.007 · DOI
  93. 2006, Effects of total enteral nutrition supplemented with a multi-fibre mix on faecal short-chain fatty acids and microbiota., Clin Nutr, 25, 82, 10.1016/j.clnu.2005.09.006 · DOI
  94. 1989, Enteral versus parenteral glucose as the sole nutritional support after colorectal resection. A prospective, randomized comparison., Scand J Gastroenterol, 24, 539, 10.3109/00365528909093086 · DOI
  95. 1992, Early enteral feeding, compared with parenteral, reduces postoperative septic complications. The results of a meta-analysis., Ann Surg, 216, 172, 10.1097/00000658-199208000-00008 · DOI
  96. 2006, Physiological response of the human pancreas to enteral and parenteral feeding., Curr Opin Clin Nutr Metab Care, 9, 622, 10.1097/01.mco.0000241675.63041.ca · DOI
  97. 2010, Combining enteral with parenteral nutrition to improve postoperative glucose control., Br J Nutr, 103, 1635, 10.1017/S0007114509993631 · DOI
  98. 2004, Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans., Am J Physiol Endocrinol Metab, 287, E199, 10.1152/ajpendo.00545.2003 · DOI · Paper page
  99. 1996, Influences of dietary energy and protein on leucine kinetics during feeding in healthy adults., Am J Physiol, 270, E282
  100. 2010, Protein balance in nondiabetic versus diabetic patients undergoing colon surgery: Effect of epidural analgesia and amino acids., Reg Anesth Pain Med, 35, 355, 10.1097/AAP.0b013e3181e66e4f · DOI
  101. 2003, Amino acid ingestion strongly enhances insulin secretion in patients with long-term type 2 diabetes., Diabetes Care, 26, 625, 10.2337/diacare.26.3.625 · DOI
  102. 2011, An oral nutrition regimen based on a pressurized whey protein promotes a positive protein balance in colorectal surgical patients by reducing whole body protein breakdown without affecting glucose kinetics., Appl Physiol Metab, 36, 441
  103. 2005, Effect of laparoscopic colon resection on postoperative glucose utilization and protein sparing: An integrated analysis of glucose and protein metabolism during the fasted and fed states using stable isotopes., Arch Surg, 140, 593, 10.1001/archsurg.140.6.593 · DOI
  104. 1976, Protein-sparing therapy in postoperative patients. Effects of added hypocaloric glucose or lipid., N Engl J Med, 294, 1411, 10.1056/NEJM197606242942601 · DOI
  105. 2007, Inadequate protein intake affects skeletal muscle transcript profiles in older humans., Am J Clin Nutr, 85, 1344, 10.1093/ajcn/85.5.1344 · DOI
  106. 2010, Protein intake and incident frailty in the Women’s Health Initiative observational study., J Am Geriatr Soc, 58, 1063, 10.1111/j.1532-5415.2010.02866.x · DOI · Paper page
  107. 2002, Influence of the protein digestion rate on protein turnover in young and elderly subjects., J Nutr, 132, 3228S, 10.1093/jn/131.10.3228S · DOI · Paper page
  108. 1998, Variation in the apparent sensitivity of the insulin-mediated inhibition of proteolysis to amino acid supply determines the efficiency of protein utilization., Clin Sci (Lond), 95, 725, 10.1042/cs0950725 · DOI
  109. 2009, Moderating the portion size of a protein-rich meal improves anabolic efficiency in young and elderly., J Am Diet Assoc, 109, 1582
  110. 1970, Contribution of protein to caloric expenditure following injury., Surgery, 68, 168
  111. 2009, Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)., JPEN J Parenter Enteral Nutr, 33, 277, 10.1177/0148607109335234 · DOI · Paper page
  112. 2000, Effect of epidural blockade on protein, glucose, and lipid metabolism in the fasted state and during dextrose infusion in volunteers., Anesthesiology, 92, 62, 10.1097/00000542-200001000-00015 · DOI
  113. 2000, Epidural blockade improves substrate utilization after surgery., Am J Physiol Endocrinol Metab, 279, E646, 10.1152/ajpendo.2000.279.3.E646 · DOI
  114. 1996, Modulation of protein metabolism in the surgical patient. Effect of 48-hour continuous epidural block with local anesthetics on leucine kinetics., Reg Anesth, 21, 430
  115. 2003, Perioperative glucose infusion and the catabolic response to surgery: The effect of epidural block., Anesth Analg, 96, 555, 10.1213/00000539-200302000-00047 · DOI
  116. 2002, The anabolic effect of epidural blockade requires energy and substrate supply., Anesthesiology, 97, 943, 10.1097/00000542-200210000-00029 · DOI
  117. 2012, Parenteral amino acids v. dextrose infusion: An anabolic strategy to minimise the catabolic response to surgery while maintaining normoglycaemia in diabetes mellitus type 2 patients., Br J Nutr, 107, 573, 10.1017/S0007114511003126 · DOI
  118. 2007, Epidural anesthesia and analgesia decrease the postoperative incidence of insulin resistance in preoperative insulin-resistant subjects only., Anesth Analg, 104, 1587, 10.1213/01.ane.0000261506.48816.5c · DOI
  119. 2006, Postoperative infusion of amino acids induces a positive protein balance independently of the type of analgesia used., Anesthesiology, 105, 253, 10.1097/00000542-200608000-00007 · DOI
  120. 2005, Enhanced recovery after surgery: A consensus review of clinical care for patients undergoing colonic resection., Clin Nutr, 24, 466, 10.1016/j.clnu.2005.02.002 · DOI
  121. 2002, Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: A randomised controlled trial., Lancet, 359, 1812, 10.1016/S0140-6736(02)08711-1 · DOI
  122. 2012, Perioperative fluid management: Consensus statement from the enhanced recovery partnership., Perioper Med (Lond), 1, 2, 10.1186/2047-0525-1-2 · DOI
  123. 2015, Fluid management and goal-directed therapy as an adjunct to Enhanced Recovery After Surgery (ERAS)., Can J Anaesth, 62, 158, 10.1007/s12630-014-0266-y · DOI
  124. 2012, Which goal for fluid therapy during colorectal surgery is followed by the best outcome: Near-maximal stroke volume or zero fluid balance?, Br J Anaesth, 109, 191, 10.1093/bja/aes163 · DOI
  125. 2010, A meta-analysis of randomised controlled trials of intravenous fluid therapy in major elective open abdominal surgery: Getting the balance right., Proc Nutr Soc, 69, 488, 10.1017/S0029665110001734 · DOI
  126. 2000, Postoperative ileus: A preventable event., Br J Surg, 87, 1480, 10.1046/j.1365-2168.2000.01595.x · DOI
  127. 2014, Update on the management of postoperative nausea and vomiting., Curr Opin Anaesthesiol, 27, 605, 10.1097/ACO.0000000000000128 · DOI
  128. 2004, Postoperative complications in the first 24 hours: A general surgery audit., J Adv Nurs, 46, 633, 10.1111/j.1365-2648.2004.03054.x · DOI
  129. 2008, Functional impact of 10 days of bed rest in healthy older adults., J Gerontol A Biol Sci Med Sci, 63, 1076, 10.1093/gerona/63.10.1076 · DOI · Paper page
  130. 2007, Calorie restriction accelerates the catabolism of lean body mass during 2 wk of bed rest., Am J Clin Nutr, 86, 366, 10.1093/ajcn/86.2.366 · DOI
  131. 2008, Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion., J Physiol, 586, 6049
  132. 2013, Disuse impairs the muscle protein synthetic response to protein ingestion in healthy men., J Clin Endocrinol Metab, 98, 4872, 10.1210/jc.2013-2098 · DOI
  133. 2004, Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass., FASEB J, 18, 1025, 10.1096/fj.03-1228fje · DOI
  134. 1999, Wasting in cancer., J Nutr, 129, 243
  135. 2002, Accelerated postoperative recovery programme after colonic resection improves physical performance, pulmonary function and body composition., Br J Surg, 89, 446, 10.1046/j.0007-1323.2001.02044.x · DOI
  136. 2002, Early oral nutrition after elective colorectal surgery: Influence of balanced analgesia and enforced mobilization., Nutrition, 18, 263, 10.1016/S0899-9007(01)00749-3 · DOI
  137. 2004, Epidural anesthesia, hypotension, and changes in intravascular volume., Anesthesiology, 100, 281, 10.1097/00000542-200402000-00016 · DOI
  138. 2013, HbA1c: A prognostic biomarker in the surgical and critically ill patient population., J Cardiothorac Vasc Anesth, 27, 760, 10.1053/j.jvca.2012.06.030 · DOI
  139. 2010, The relationship between glycosylated hemoglobin and perioperative glucose control in patients with diabetes., Can J Anaesth, 57, 322, 10.1007/s12630-010-9266-8 · DOI
  140. 2012, Preoperative hemoglobin A1c and postoperative glucose control in outcomes after gastric bypass for obesity., Surg Obes Relat Dis, 8, 685, 10.1016/j.soard.2011.08.002 · DOI
  141. 2009, Haemoglobin A1c as a predictor of postoperative hyperglycaemia and complications after major colorectal surgery., Br J Surg, 96, 1358, 10.1002/bjs.6724 · DOI
  142. 2005, Admission glucose and mortality in elderly patients hospitalized with acute myocardial infarction: Implications for patients with and without recognized diabetes., Circulation, 111, 3078, 10.1161/CIRCULATIONAHA.104.517839 · DOI · Paper page
  143. 2008, Glucometrics in patients hospitalized with acute myocardial infarction: Defining the optimal outcomes-based measure of risk., Circulation, 117, 1018, 10.1161/CIRCULATIONAHA.107.740498 · DOI · Paper page
  144. 2010, The prevalence of undiagnosed diabetes in non-cardiac surgery patients, an observational study., Can J Anaesth, 57, 1058, 10.1007/s12630-010-9391-4 · DOI
  145. 2009, Development of an American College of Surgeons National Surgery Quality Improvement Program: Morbidity and mortality risk calculator for colorectal surgery., J Am Coll Surg, 208, 1009, 10.1016/j.jamcollsurg.2009.01.043 · DOI
  146. 2010, Submaximal cardiopulmonary exercise testing predicts complications and hospital length of stay in patients undergoing major elective surgery., Ann Surg, 251, 535, 10.1097/SLA.0b013e3181cf811d · DOI
  147. 2010, Impaired functional capacity is associated with all-cause mortality after major elective intra-abdominal surgery., Br J Anaesth, 105, 297, 10.1093/bja/aeq128 · DOI
  148. 2004, Physiological complexity, aging, and the path to frailty., Sci Aging Knowledge Environ, 2004, pe16
  149. 2004, Preoperative optimization of the high-risk surgical patient., Br J Anaesth, 93, 121, 10.1093/bja/aeh164 · DOI
  150. 1993, Preoperative evaluation of cardiac failure and ischemia in elderly patients by cardiopulmonary exercise testing., Chest, 104, 701, 10.1378/chest.104.3.701 · DOI
  151. 2013, The association of the distance walked in 6 min with pre-operative peak oxygen consumption and complications 1 month after colorectal resection., Anaesthesia, 68, 811, 10.1111/anae.12329 · DOI
  152. 2014, Patient frailty: The elephant in the operating room., Anaesthesia, 69, 26
  153. 2011, Accumulated frailty characteristics predict postoperative discharge institutionalization in the geriatric patient., J Am Coll Surg, 213, 37, 10.1016/j.jamcollsurg.2011.01.056 · DOI
  154. 2013, Accumulating deficits model of frailty and postoperative mortality and morbidity: Its application to a national database., J Surg Res, 183, 104, 10.1016/j.jss.2013.01.021 · DOI
  155. 2005, Optimizing functional exercise capacity in the elderly surgical population., Curr Opin Clin Nutr Metab Care, 8, 23, 10.1097/00075197-200501000-00005 · DOI
  156. 2005, Increased length of hospital stay in underweight and overweight patients at hospital admission: A controlled population study., Clin Nutr, 24, 273
  157. 2012, Postoperative loss of skeletal muscle mass, complications and quality of life in patients undergoing cardiac surgery., Nutrition, 28, 40, 10.1016/j.nut.2011.02.007 · DOI
  158. 2011, Impact of preoperative change in physical function on postoperative recovery: Argument supporting prehabilitation for colorectal surgery., Surgery, 150, 505, 10.1016/j.surg.2011.07.045 · DOI
  159. 1988, Functional ambulation velocity and distance requirements in rural and urban communities. A clinical report., Phys Ther, 68, 1371, 10.1093/ptj/68.9.1371 · DOI
  160. 2001, Reference values for a multiple repetition 6-minute walk test in healthy adults older than 20 years., J Cardiopulm Rehabil, 21, 87, 10.1097/00008483-200103000-00005 · DOI
  161. 2008, Validating the six-minute walk test as a measure of recovery after elective colon resection surgery., Arch Phys Med Rehabil, 89, 1083, 10.1016/j.apmr.2007.11.031 · DOI

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Metadata

Authors
Gillis, C., & Carli, F.
Affiliations
McGill University Health Centre (CA)
Corresponding author
Carli, Francesco
ORCID
Venue
Anesthesiology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2015-12
Volume
123
Issue
6
Pages
1455-1472
ISSN
0003-3022 (ISSN-L)
DOI
10.1097/aln.0000000000000795
OpenAlex
W1905230518
Cited by
350
References
0
Citations by year
2026: 44 · 2025: 38 · 2024: 56 · 2023: 51 · 2022: 44 · 2021: 31 · 2020: 34 · 2019: 18 · 2018: 15 · 2017: 11 · 2016: 7
FWCI
2.11
Type
journal article
Language
en
Open access
closed
Locations
  • Anesthesiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
McGill University Health Centre
Topics
  • Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hyperglycemia and glycemic control in critically ill and hospitalized patients
Keywords
perioperative nutrition, enhanced recovery after surgery, surgical stress response, intermediary metabolism, catabolism, carbohydrate loading, early oral feeding, prehabilitation, preoperative glycemic control, immunoprotection, malnutrition
MeSH terms
Humans, Nutritional Status, Postoperative Complications, Preoperative Care, Surgical Procedures, Operative, Nutritional Support, Perioperative Care

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