Cited by 63Obstructive Sleep Apnea ResearchNasal Surgery and Airway StudiesSleep and related disorders

Apnea–hypopnea index decreased significantly after nasal surgery for obstructive sleep apnea: A meta-analysis

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Wu, Jun, Zhao, Guoqiang, Li, Yunchuan, Zang, Hongrui, Wang, Tong, Wang, Dongbo, Han, Demin·2017·Medicine

Abstract

BACKGROUND: Nasal surgeries have been applied to obstructive sleep apnea (OSA) patients with nasal obstruction for decades. However, the efficiency of nasal surgery in improving OSA remains controversial.The aim of this study was to identify whether isolated nasal surgery can improve apnea-hypopnea index (AHI). METHODS: Computerized searches were performed in MEDLINE, Web of Science, Cochrane Library, and Scopus from January 1, 2000 to April 30, 2016. A total of 18 articles and 587 participants were included. There were 1 randomized controlled trials, 2 nonrandomized trials, 11 prospective studies, and 4 retrospective studies. Data regarding study design (prospective/retrospective clinical trial, randomized, and controlled), population size, participant characteristics (age, gender, and body mass index), surgical intervention, and outcomes (AHI, Epworth sleep scale [ESS]) was collected. RESULTS: Statistically significant improvement in AHI (subgroup 1: weighted mean difference [WMD] [95%confidence interval (CI)], -4.17 [-7.62, -0.73]; subgroup 2: WMD [95%CI], -4.19 [-7.51, -0.88]; overall: WMD [95%CI], -4.15 [-6.48, -1.82]) and ESS (subgroup 1: WMD [95%CI], -2.14 [-3.08, -1.19]; subgroup 2: WMD [95%CI], -4.70 [-5.95, -3.44]; overall: WMD [95%CI], -4.08 [-5.27, -2.88]) was revealed. CONCLUSION: Both AHI and ESS improved significantly after isolated nasal surgery, but the improvement of AHI is slightly significant. Future randomized controlled trials are needed to confirm the long-term benefits of nasal surgery on OSA.

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Authors
Wu, J., Zhao, G., Li, Y., Zang, H., Wang, T., Wang, D., & Han, D.
Affiliations
Beijing Tongren Hospital (CN)
Corresponding author
Han, Demin
Venue
Medicine
Published
2017-02
Volume
96
Issue
5
Pages
e6008
ISSN
0025-7974 (ISSN-L)
OpenAlex
W2616986898
Cited by
61
References
41
Citations by year
2026: 6 · 2025: 4 · 2024: 8 · 2023: 7 · 2022: 11 · 2021: 8 · 2020: 5 · 2019: 5 · 2018: 5 · 2017: 2
FWCI
0.57
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Medicine (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
  • Health Sciences › Medicine › Surgery › Nasal Surgery and Airway Studies
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Keywords
obstructive sleep apnea, nasal surgery, apnea-hypopnea index, nasal obstruction, Epworth Sleepiness Scale, sleep-disordered breathing, surgical outcomes
MeSH terms
Adult, Aged, Female, Humans, Male, Middle Aged, Postoperative Period, Severity of Illness Index, Treatment Outcome, Sleep Apnea, Obstructive, Young Adult, Nasal Surgical Procedures

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