Providing a sense of touch to prosthetic hands
Abstract
Each year, approximately 185,000 Americans suffer the devastating loss of a limb. The effects of upper limb amputations are profound because a person's hands are tools for everyday functioning, expressive communication, and other uniquely human attributes. Despite the advancements in prosthetic technology, current upper limb prostheses are still limited in terms of complex motor control and sensory feedback. Sensory feedback is critical to restoring full functionality to amputated patients because it would relieve the cognitive burden of relying solely on visual input to monitor motor commands and provide tremendous psychological benefits. This article reviews the latest innovations in sensory feedback and argues in favor of peripheral nerve interfaces. First, the authors examine the structure of the peripheral nerve and its importance in the development of a sensory interface. Second, the authors discuss advancements in targeted muscle reinnervation and direct neural stimulation by means of intraneural electrodes. The authors then explore the future of prosthetic sensory feedback using innovative technologies for neural signaling, specifically, the sensory regenerative peripheral nerve interface and optogenetics. These breakthroughs pave the way for the development of a prosthetic limb with the ability to feel.
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Nghiem et al. (2015) proposed a method using an insulated electrode on muscle surface to stimulate muscle, which then depolarizes afferent nerve within the muscle to provide sensory feedback.
“Another methodology to attain feedback has been proposed by Nghiem et al. (2015), which can be used for transferring sensory signals from a prosthetic sensor to the residual nerve. In this method, an insulated electrode placed on the surface of a muscle was used to stimulate the muscle, which then depolarized the afferent nerve within the muscle to provide sensory feedback.”
From Selectivity and Longevity of Peripheral-Nerve and Machine Interfaces: A Review. (2017) · cites this paper as Nghiem et al. (2015)
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“Another methodology to attain feedback has been proposed by Nghiem et al. (2015), which can be used for transferring sensory signals from a prosthetic sensor to the residual nerve.”
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- Authors
- Nghiem, B. T., Sando, I. C., Gillespie, R. B., McLaughlin, B. L., Gerling, G. J., Langhals, N. B., Urbanchek, M. G., & Cederna, P. S.
- Affiliations
- Draper Laboratory (US)
- Michigan Medicine (US)
- University of Virginia (US)
- ORCID
- Venue
- Plastic and Reconstructive Surgery
- Published
- 2015-06
- Volume
- 135
- Issue
- 6
- Pages
- 1652-1663
- ISSN
- 0032-1052 (ISSN-L)
- OpenAlex
- W432310612
- Cited by
- 104
- References
- 10
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 9 · 2023: 10 · 2022: 11 · 2021: 14 · 2020: 11 · 2019: 9 · 2018: 8 · 2017: 9 · 2016: 8
- FWCI
- 3.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Plastic & Reconstructive Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Engineering › Biomedical Engineering › Muscle activation and electromyography studies
- Physical Sciences › Engineering › Biomedical Engineering › Prosthetics and Rehabilitation Robotics
- Keywords
- prosthetic hand, sensory feedback, upper limb amputation, peripheral nerve interfaces, targeted muscle reinnervation, optogenetics, neuronal signaling, prosthesis development
- MeSH terms
- Amputation, Traumatic, Artificial Limbs, Female, Forecasting, Hand, Humans, Male, Prosthesis Design, Psychomotor Performance, Sensory Thresholds, Touch, Treatment Outcome, Prosthesis Fitting, Touch Perception, Feedback, Sensory, Brain-Computer Interfaces
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