Cited by 662HIV/AIDS Research and InterventionsHIV Research and TreatmentStress Responses and Cortisol

The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.

Role of Depression, Stress, and Trauma in HIV Disease Progression

Leserman, Jane·2008·Psychosomatic Medicine

Open this paper in CoChat — free account

Abstract

Despite advances in HIV treatment, there continues to be great variability in the progression of this disease. This paper reviews the evidence that depression, stressful life events, and trauma account for some of the variation in HIV disease course. Longitudinal studies both before and after the advent of highly active antiretroviral therapies (HAART) are reviewed. To ensure a complete review, PubMed was searched for all English language articles from January 1990 to July 2007. We found substantial and consistent evidence that chronic depression, stressful events, and trauma may negatively affect HIV disease progression in terms of decreases in CD4 T lymphocytes, increases in viral load, and greater risk for clinical decline and mortality. More research is warranted to investigate biological and behavioral mediators of these psychoimmune relationships, and the types of interventions that might mitigate the negative health impact of chronic depression and trauma. Given the high rates of depression and past trauma in persons living with HIV/AIDS, it is important for healthcare providers to address these problems as part of standard HIV care.

Integrity signals

Registry

Crossref · 10.1097/psy.0b013e3181777a5f

Cites

63 of 63 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Depression Is a Risk Factor for Noncompliance With Medical Treatment: Meta-analysis of the Effects of Anxiety and Depression on Patient Adherence
DiMatteo, M. R., Lepper, H. S., & Croghan, T. W. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.14.2101 · Cited by 4,177
Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection
Paterson, D. L., Swindells, S., Mohr, J. A., Brester, M., Vergis, E. N., Squier, C. L., Wagener, M. M., & Singh, N. (2000) · Annals of Internal Medicine · doi:10.7326/0003-4819-133-1-200007040-00004 · Cited by 3,289
Stress and immunity in humans: a meta-analytic review.
Herbert, T. B., & Cohen, S. (1993) · Psychosomatic Medicine · doi:10.1097/00006842-199307000-00004 · Cited by 1,100
Mortality, CD4 Cell Count Decline, and Depressive Symptoms Among HIV-Seropositive Women
Ickovics, J. R., Hamburger, M. E., Vlahov, D., Schoenbaum, E. E., Schuman, P. C., BOLAND, R. J., & Moore, J. (2001) · JAMA · doi:10.1001/jama.285.11.1466 · Cited by 885
Depression and immunity: A meta-analytic review.
Herbert, T. B., & Cohen, S. (1993) · Psychological Bulletin · doi:10.1037/0033-2909.113.3.472 · Cited by 812
Cognitive processing, discovery of meaning, CD4 decline, and AIDS-related mortality among bereaved HIV-seropositive men.
Bower, J. E., Kemeny, M. E., Taylor, S. E., & Fahey, J. L. (1998) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.66.6.979 · Cited by 465
Progression to AIDS
Leserman, J., Jackson, E. D., Petitto, J. M., Golden, R. N., Silva, S. G., Perkins, D. O., Cai, J., Folds, J. D., & Evans, D. L. (1999) · Psychosomatic Medicine · doi:10.1097/00006842-199905000-00021 · Cited by 441
Self-citation
Estrogen Replacement Therapy and Ovarian Cancer Mortality in a Large Prospective Study of US Women
Rodríguez, C. (2001) · JAMA · doi:10.1001/jama.285.11.1460 · Cited by 424
Depressive Symptoms and AIDS-Related Mortality Among a Multisite Cohort of HIV-Positive Women
Cook, J. Α., Grey, D. D., Burke-Miller, J. K., Cohen, M. H., Gurtman, A., Richardson, J. L., Wilson, T. E., Young, M., & Hessol, N. A. (2004) · American Journal of Public Health · doi:10.2105/ajph.94.7.1133 · Cited by 396

Flagged first, then by citations

Show all 63 references

Sorted by citations

A Handbook for the Study of Mental Health Second Edition
Scheid, T. L., & Brown, T. N. (2009) · Cited by 1,320
HIV Stigma Mechanisms and Well-Being Among PLWH: A Test of the HIV Stigma Framework
Earnshaw, V. A., Smith, L. R., Chaudoir, S. R., Amico, K. R., & Copenhaver, M. M. (2013) · AIDS and Behavior · doi:10.1007/s10461-013-0437-9 · Cited by 805
Depression and HIV/AIDS Treatment Nonadherence: A Review and Meta-analysis
Gonzalez, J. S., Batchelder, A., Psaros, C., & Safren, S. A. (2011) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31822d490a · Cited by 820
Mental health and HIV/AIDS: the need for an integrated response
Remien, R. H., Stirratt, M. J., Nguyen, N., Robbins, R. N., Pala, A. N., & Mellins, C. A. (2019) · AIDS · doi:10.1097/qad.0000000000002227 · Cited by 727
Ten Surprising Facts About Stressful Life Events and Disease Risk
Cohen, S., Murphy, M. L. M., & Prather, A. A. (2019) · Annual Review of Psychology · doi:10.1146/annurev-psych-010418-102857 · Cited by 531
Gender and Mental Health
Rosenfield, S., & Mouzon, D. M. (2012) · Handbooks of sociology and social research · doi:10.1007/978-94-007-4276-5_14 · Cited by 592
Framing Mechanisms Linking HIV-Related Stigma, Adherence to Treatment, and Health Outcomes
Turan, B., Hatcher, A. M., Weiser, S. D., Johnson, M. O., Rice, W. S., & Turan, J. M. (2017) · American Journal of Public Health · doi:10.2105/ajph.2017.303744 · Cited by 522
Depression in HIV Infected Patients: a Review
Nanni, M. G., Caruso, R., Mitchell, A. J., Meggiolaro, E., & Grassi, L. (2015) · Current Psychiatry Reports · doi:10.1007/s11920-014-0530-4 · Cited by 511
Trauma, Mental Health, Distrust, and Stigma Among HIV-Positive Persons: Implications for Effective Care
Whetten, K., Reif, S., Whetten, R., & Murphy-McMillan, L. K. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31817749dc · Cited by 352
HIV and depression: 2008 review and update
Rabkin, J. G. (2008) · Current HIV/AIDS Reports · doi:10.1007/s11904-008-0025-1 · Cited by 345
Depression and immunity: A role for T cells?
Miller, A. H. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2009.09.009 · Cited by 345
A review of psychological correlates of adjustment in patients with multiple sclerosis
Dennison, L., Moss-Morris, R., & Chalder, T. (2009) · Clinical Psychology Review · doi:10.1016/j.cpr.2008.12.001 · Cited by 330
Quality of life: The ultimate outcome measure of interventions in major depressive disorder
IsHak, W. W., Greenberg, J. M., Balayan, K., Kapitanski, N., Jeffrey, J., Fathy, H., Fakhry, H., & Rapaport, M. H. (2011) · Harvard Review of Psychiatry · doi:10.3109/10673229.2011.614099 · Cited by 313
Life Stress and Health: A Review of Conceptual Issues and Recent Findings
Slavich, G. M. (2016) · Teaching of Psychology · doi:10.1177/0098628316662768 · Cited by 300
Labeling and Stigma
Link, B. G., & Phelan, J. C. (2012) · Handbooks of sociology and social research · doi:10.1007/978-94-007-4276-5_25 · Cited by 314
Alcohol Use and Human Immunodeficiency Virus (HIV) Infection: Current Knowledge, Implications, and Future Directions
Williams, E. C., Hahn, J. A., Saitz, R., Bryant, K., Lira, M. C., & Samet, J. H. (2016) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.13204 · Cited by 294
Assessing Lifetime Stress Exposure Using the Stress and Adversity Inventory for Adults (Adult STRAIN): An Overview and Initial Validation
Slavich, G. M., & Shields, G. S. (2018) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000534 · Cited by 268
Excess Burden of Depression among HIV-Infected Persons Receiving Medical Care in the United States: Data from the Medical Monitoring Project and the Behavioral Risk Factor Surveillance System
Do, A. N., Rosenberg, E. S., Sullivan, P. S., Beer, L., Strine, T. W., Schulden, J. D., Fagan, J. L., Freedman, M. S., & Skarbinski, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092842 · Cited by 274
Mental health in hypertension: assessing symptoms of anxiety, depression and stress on anti-hypertensive medication adherence
Kretchy, I. A., Owusu-Daaku, F. T., & Danquah, S. A. (2014) · International Journal of Mental Health Systems · doi:10.1186/1752-4458-8-25 · Cited by 264
The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D)
Raison, C. L., & Miller, A. H. (2013) · Molecular Psychiatry · doi:10.1038/mp.2012.2 · Cited by 253
Maternal depressive symptoms and early childhood cognitive development: a meta-analysis
Liu, Y., Kaaya, S., Chai, J., McCoy, D. C., Surkan, P. J., Black, M. M., Sutter‐Dallay, A., Verdoux, H., & Smith-Fawzi, M. C. (2016) · Psychological Medicine · doi:10.1017/s003329171600283x · Cited by 245
HIV infection and depression
Arseniou, S., Arvaniti, A., & Samakouri, M. A. (2013) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12097 · Cited by 231
HIV Stigma and Physical Health Symptoms: Do Social Support, Adaptive Coping, and/or Identity Centrality Act as Resilience Resources?
Earnshaw, V. A., Lang, S. M., Lippitt, M., Jin, H., & Chaudoir, S. R. (2014) · AIDS and Behavior · doi:10.1007/s10461-014-0758-3 · Cited by 254
Cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected injection drug users: A randomized controlled trial.
Safren, S. A., O’Cleirigh, C. M., Bullis, J. R., Otto, M. W., Stein, M. D., & Pollack, M. H. (2012) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0028208 · Cited by 221
The validity of the Patient Health Questionnaire for screening depression in chronic care patients in primary health care in South Africa
Bhana, A., Rathod, S. D., Selohilwe, O., Kathree, T., & Petersen, I. (2015) · BMC Psychiatry · doi:10.1186/s12888-015-0503-0 · Cited by 197
Do Positive Psychosocial Factors Predict Disease Progression in HIV-1? A Review of the Evidence
Ironson, G. H., & Hayward, H. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318177216c · Cited by 192
Behavior Matters
Fisher, E. B., Fitzgibbon, M., Glasgow, R. E., Haire-Joshu, D. L., Hayman, L. L., Kaplan, R. M., Nanney, M. S., & Ockene, J. K. (2011) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2010.12.031 · Cited by 197
Alcohol and HIV Disease Progression: Weighing the Evidence
Hahn, J. A., & Samet, J. H. (2010) · Current HIV/AIDS Reports · doi:10.1007/s11904-010-0060-6 · Cited by 181
A randomized controlled trial of mindfulness-based stress reduction to manage affective symptoms and improve quality of life in gay men living with HIV
Gayner, B., Esplen, M. J., DeRoche, P., Wong, J., Bishop, S., Kavanagh, L., & Butler, K. (2012) · Journal of Behavioral Medicine · doi:10.1007/s10865-011-9350-8 · Cited by 171
Mental Health in Women Living With HIV: The Unique and Unmet Needs
Waldron, E. M., Burnett‐Zeigler, I., Wee, V., Ng, Y. K. W., Koenig, L. J., Pederson, A. B., Tomaszewski, E. P., & Miller, E. S. (2021) · Journal of the International Association of Providers of AIDS Care (JIAPAC) · doi:10.1177/2325958220985665 · Cited by 174
The impact of mental health and traumatic life experiences on antiretroviral treatment outcomes for people living with HIV/AIDS
Pence, B. W. (2009) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkp006 · Cited by 158
Validation of brief screening tools for depressive and alcohol use disorders among TB and HIV patients in primary care in Zambia
Chishinga, N., Kinyanda, E., Weiss, H. A., Patel, V., Ayles, H., & Seedat, S. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-75 · Cited by 146
View of God as benevolent and forgiving or punishing and judgmental predicts HIV disease progression
Ironson, G. H., Stuetzle, R., Ironson, D., Balbin, E., Kremer, H., George, A., Schneiderman, N., & FLETCHER, M. A. (2011) · Journal of Behavioral Medicine · doi:10.1007/s10865-011-9314-z · Cited by 149
Mental Health: A Focus on Stress, Coping, and Mental Illness as it Relates to Treatment Retention, Adherence, and Other Health Outcomes
Blashill, A. J., Perry, N., & Safren, S. A. (2011) · Current HIV/AIDS Reports · doi:10.1007/s11904-011-0089-1 · Cited by 147
Effects of Psychological Interventions on Neuroendocrine Hormone Regulation and Immune Status in HIV-Positive Persons: A Review of Randomized Controlled Trials
Carrico, A. W., & Antoni, M. H. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31817a5d30 · Cited by 140
Psychiatric Risk Factors for HIV Disease Progression: The Role of Inconsistent Patterns of Antiretroviral Therapy Utilization
Carrico, A. W., Riley, E. D., Johnson, M. O., Charlebois, E. D., Neilands, T. B., Remien, R. H., Lightfoot, M. A., Steward, W. T., Weinhardt, L. S., Kelly, J. A., et al. (2010) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e318201df63 · Cited by 137
The Depression Treatment Cascade in Primary Care: A Public Health Perspective
Pence, B. W., O’Donnell, J. K., & Gaynes, B. N. (2012) · Current Psychiatry Reports · doi:10.1007/s11920-012-0274-y · Cited by 133
Pain, Mood, and Substance Abuse in HIV
Merlin, J. S., Westfall, A. O., Raper, J. L., Zinski, A., Norton, W. E., Willig, J. H., Gross, R., Ritchie, C. S., Saag, M. S., & Mugavero, M. J. (2012) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3182662215 · Cited by 132
Stress and Poverty Predictors of Treatment Adherence Among People With Low-Literacy Living With HIV/AIDS
Kalichman, S. C., & Grebler, T. (2010) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181f01be3 · Cited by 129
The shifting landscape of health care: toward a model of health care empowerment.
Johnson, M. O. (2011) · American Journal of Public Health · doi:10.2105/ajph.2009.189829 · Cited by 134
Overload: Impact of Incident Stressful Events on Antiretroviral Medication Adherence and Virologic Failure in a Longitudinal, Multisite Human Immunodeficiency Virus Cohort Study
Mugavero, M. J., Raper, J. L., Reif, S., Whetten, K., Leserman, J., Thielman, N. M., & Pence, B. W. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181bfe8d2 · Cited by 122
Self-citation
Common mental disorders in TB/HIV co-infected patients in Ethiopia
Deribew, A., Tesfaye, M., Hailmichael, Y., Apers, L., Abebe, G., Duchateau, L., & Colebunders, R. (2010) · BMC Infectious Diseases · doi:10.1186/1471-2334-10-201 · Cited by 121
A Review of Recent Literature on Trauma Among Individuals Living with HIV
LeGrand, S., Reif, S., Sullivan, K., Murray, K., Barlow, M. L., & Whetten, K. (2015) · Current HIV/AIDS Reports · doi:10.1007/s11904-015-0288-2 · Cited by 121
Adverse psychosocial factors predict poorer prognosis in HIV disease: A meta-analytic review of prospective investigations
Chida, Y., & Vedhara, K. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2009.01.013 · Cited by 124
Is intimate partner violence associated with HIV infection among women in the United States?
Sareen, J., Pagura, J., & Grant, B. F. (2009) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2009.02.004 · Cited by 115
Feasibility and Acceptability of a Task-Shifted Intervention to Enhance Adherence to HIV Medication and Improve Depression in People Living with HIV in Zimbabwe, a Low Income Country in Sub-Saharan Africa
Abas, M., Nyamayaro, P. C., Bere, T. C., Saruchera, E., Mothobi, N. Z., Simms, V. M., Mangezi, W. O., Macpherson, K., Croome, N., Magidson, J. F., et al. (2017) · AIDS and Behavior · doi:10.1007/s10461-016-1659-4 · Cited by 116
Prevalence of depression or depressive symptoms among people living with HIV/AIDS in China: a systematic review and meta-analysis
Wang, T., Fu, H., Kaminga, A. C., Li, Z., Guo, G., Chen, L., & Li, Q. (2018) · BMC Psychiatry · doi:10.1186/s12888-018-1741-8 · Cited by 110
Relationship Between Spiritual Coping and Survival in Patients with HIV
Ironson, G. H., Kremer, H., & Lucette, A. (2016) · Journal of General Internal Medicine · doi:10.1007/s11606-016-3668-4 · Cited by 114
Predictors of Late Presentation for HIV Diagnosis: A Literature Review and Suggested Way Forward
Mukolo, A., Villegas, R., Aliyu, M. H., & Wallston, K. A. (2012) · AIDS and Behavior · doi:10.1007/s10461-011-0097-6 · Cited by 115
The Influence of Depression on the Progression of HIV
Schuster, R. M., Bornovalova, M. A., & Hunt, E. D. (2011) · Behavior Modification · doi:10.1177/0145445511425231 · Cited by 108
Validity of an interviewer-administered patient health questionnaire-9 to screen for depression in HIV-infected patients in Cameroon
Pence, B. W., Gaynes, B. N., Atashili, J., O’Donnell, J. K., Tayong, G., Kats, D., Whetten, R., Whetten, K., NJAMNSHI, A. K., & Ndumbe, P. M. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.05.056 · Cited by 105
Food Insecurity is Longitudinally Associated with Depressive Symptoms Among Homeless and Marginally-Housed Individuals Living with HIV
Palar, K., Kushel, M., Frongillo, E. A., Riley, E. D., Grede, N., Bangsberg, D. R., & Weiser, S. D. (2014) · AIDS and Behavior · doi:10.1007/s10461-014-0922-9 · Cited by 102
HIV-related stigma and symptoms of post-traumatic stress disorder and depression in HIV-infected individuals: does social support play a mediating or moderating role?
Breet, E., Kagee, A., & Seedat, S. (2014) · AIDS Care · doi:10.1080/09540121.2014.901486 · Cited by 101
Social support and the psychological wellbeing of people living with HIV/AIDS in Ghana
Asante, K. O. (2012) · African Journal of Psychiatry · doi:10.4314/ajpsy.v15i5.42 · Cited by 101
Randomized controlled trial evaluating the effect of an interactive group counseling intervention for HIV-positive women on prenatal depression and disclosure of HIV status
Kaaya, S., Blander, J., Antelman, G., Cyprian, F., Emmons, K. M., Matsumoto, K., Chopyak, E., Levine, M., & Fawzi, M. C. S. (2013) · AIDS Care · doi:10.1080/09540121.2013.763891 · Cited by 101
An evaluation of quality of life and its determinants among people living with HIV/AIDS from Southern Brazil
Passos, S. M. K., & Souza, L. D. D. M. (2015) · Cadernos de Saúde Pública · doi:10.1590/0102-311x00000514 · Cited by 98
Global Systematic Review of Common Mental Health Disorders in Adults Living with HIV
Hoare, J., Sevenoaks, T., Mtukushe, B., Williams, T., Heany, S. J., & Phillips, N. J. (2021) · Current HIV/AIDS Reports · doi:10.1007/s11904-021-00583-w · Cited by 99
Altered populations of natural killer cells, cytotoxic T lymphocytes, and regulatory T cells in major depressive disorder: Association with sleep disturbance
Suzuki, H., Savitz, J. B., Teague, T. K., Gandhapudi, S. K., Tan, C., Misaki, M., McKinney, B. A., Irwin, M. R., Drevets, W. C., & Bodurka, J. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.06.011 · Cited by 96
Mental Health Services in South Africa: Taking stock
Lund, C., Petersen, I., Kleintjes, S., & Bhana, A. (2012) · African Journal of Psychiatry · doi:10.4314/ajpsy.v15i6.48 · Cited by 94
The Adverse Effects of Psychological Stress on Immunoregulatory Balance: Applications to Human Inflammatory Diseases
Marshall, G. D. (2010) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2010.09.013 · Cited by 93
Serum kynurenic acid is reduced in affective psychosis
Wurfel, B. E., Drevets, W. C., Bliss, S. A., McMillin, J. R., Suzuki, H., Ford, B. N., Morris, H. M., Teague, T. K., Dantzer, R., & Savitz, J. B. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.88 · Cited by 91
Psychosocial Influences on HIV-1 Disease Progression: Neural, Endocrine, and Virologic Mechanisms
Cole, S. W. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181773bbd · Cited by 92
Physical, Emotional, and Psychosocial Challenges Associated with Daily Dosing of HIV Medications and Their Impact on Indicators of Quality of Life: Findings from the Positive Perspectives Study
Rios, P. D. L., Okoli, C., Castellanos, E., Allan, B., Young, B., Brough, G., Muchenje, M., Eremin, A., Corbelli, G. M., McBritton, M., et al. (2020) · AIDS and Behavior · doi:10.1007/s10461-020-03055-1 · Cited by 91
Depressive symptoms, self-esteem, HIV symptom management self-efficacy and self-compassion in people living with HIV
Eller, L. S., Rivero‐Méndez, M., Voss, J. G., Chen, W.-T., Chaiphibalsarisdi, P., Iipinge, S. N., Johnson, M. O., Portillo, C. J., Corless, I. B., Sullivan, K. M., et al. (2013) · AIDS Care · doi:10.1080/09540121.2013.841842 · Cited by 99
Overview of HIV
Klimas, N. G., Koneru, A. O., & FLETCHER, M. A. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31817ae69f · Cited by 91
How disclosure and antiretroviral therapy help HIV-infected adolescents in sub-Saharan Africa cope with stigma
Midtbø, V., Shirima, V., Skovdal, M., & Daniel, M. (2012) · African Journal of AIDS Research · doi:10.2989/16085906.2012.734987 · Cited by 90
Effects of behavioral stress reduction Transcendental Meditation intervention in persons with HIV
Chhatre, S., Metzger, D. S., Frank, I., Boyer, J., Thompson, E., Nidich, S. I., Montaner, L. J., & Jayadevappa, R. (2013) · AIDS Care · doi:10.1080/09540121.2013.764396 · Cited by 91
Behavioral Mediation of the Relationship Between Psychosocial Factors and HIV Disease Progression
Gore-Felton, C. E., & Koopman, C. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318177353e · Cited by 86
Depression as an evolutionary strategy for defense against infection
Anders, S. L., Tanaka, M., & Kinney, D. K. (2012) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2012.12.002 · Cited by 87
A Syndemic of Psychosocial Problems Places the MSM (Men Who Have Sex with Men) Population at Greater Risk of HIV Infection
Wu, J., Ci-yong, L., Xueqing, D., Wang, H., & Lingyao, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032312 · Cited by 83
Prevalence of depression and anxiety disorders in HIV-positive outpatients in rural Tanzania
Marwick, K. F. M., & Kaaya, S. (2010) · AIDS Care · doi:10.1080/09540120903253981 · Cited by 85
Depression in patients with HIV is under‐diagnosed: a cross‐sectional study in Denmark
Rodkjær, L. Ø., Laursen, T. L., Balle, N., & Sodemann, M. (2009) · HIV Medicine · doi:10.1111/j.1468-1293.2009.00741.x · Cited by 84
Social support, stress coping strategies, resilience and posttraumatic growth in a Polish sample of HIV-infected individuals: results of a 1 year longitudinal study
Rzeszutek, M., Oniszczenko, W., & Firląg‐Burkacka, E. (2017) · Journal of Behavioral Medicine · doi:10.1007/s10865-017-9861-z · Cited by 94
Emotional support and gender in people living with HIV: effects on psychological well-being
The Eurosupport Study Group, Gordillo, V. C., Fekete, E. M., Platteau, T., Antoni, M. H., Schneiderman, N., & Nöstlinger, C. (2009) · Journal of Behavioral Medicine · doi:10.1007/s10865-009-9222-7 · Cited by 78
HIV stigma and viral load among African-American women receiving treatment for HIV
Kemp, C. G., Lipira, L. E., Huh, D., Nevin, P. E., Turan, J. M., Simoni, J. M., Cohn, S. E., Bahk, M., Berzins, B., Andrasik, M. P., et al. (2019) · AIDS · doi:10.1097/qad.0000000000002212 · Cited by 81
Transgender women and HIV-related health disparities: falling off the HIV treatment cascade
Kalichman, S. C., Hernandez, D. B., Finneran, S. D., Price, D. M., & Driver, R. (2017) · Sexual Health · doi:10.1071/sh17015 · Cited by 81
High Levels of Syndemics and Their Association with Adherence, Viral Non-suppression, and Biobehavioral Transmission Risk in Miami, a U.S. City with an HIV/AIDS Epidemic
Glynn, T. R., Safren, S. A., Carrico, A. W., Mendez, N. A., Duthely, L. M., Dale, S. K., Jones, D. L., Feaster, D. J., & Rodriguez, A. E. (2019) · AIDS and Behavior · doi:10.1007/s10461-019-02619-0 · Cited by 79
Coping with HIV Stigma: Do Proactive Coping and Spiritual Peace Buffer the Effect of Stigma on Depression?
Chaudoir, S. R., Norton, W. E., Earnshaw, V. A., Moneyham, L. L., Mugavero, M. J., & Hiers, K. M. (2011) · AIDS and Behavior · doi:10.1007/s10461-011-0039-3 · Cited by 77
Mental Illness and the Criminal Justice System
Hiday, V. A., & Burns, P. J. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511984945.029 · Cited by 79
Effectiveness of Mindfulness-Based Cognitive Therapy on the Quality of Life, Emotional Status, and CD4 Cell Count of Patients Aging with HIV Infection
González-García, M., Ferrer, M. J., Borràs, X., Muñoz-Moreno, J. A., Miranda, C., Puig, J., Pérez‐Álvarez, N., Soler, J., Feliu‐Soler, A., Clotet, B., et al. (2013) · AIDS and Behavior · doi:10.1007/s10461-013-0612-z · Cited by 84
Effects of exercise on depression and anxiety in persons living with HIV: A meta-analysis
Heißel, A., Zech, P. A., Rapp, M. A., Schuch, F. B., Lawrence, J. B., Kangas, M., & Heinzel, S. (2019) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.109823 · Cited by 76
Psychosocial Functioning and Depressive Symptoms Among HIV-Positive Persons Receiving Care and Treatment in Kenya, Namibia, and Tanzania
Seth, P., Kidder, D. P., Pals, S. L., Parent, J., Mbatia, R., Chesang, K., Mbilinyi, D., Koech, E., Nkingwa, M., Katuta, F., et al. (2013) · Prevention Science · doi:10.1007/s11121-013-0420-8 · Cited by 76
Randomized Controlled Trial of Mindfulness-Based Stress Reduction Delivered to Human Immunodeficiency Virus–Positive Patients in Iran: Effects on CD4+ T Lymphocyte Count and Medical and Psychological Symptoms
SeyedAlinaghi, S., Jam, S., Foroughi, M., Imani, A., Mohraz, M., Djavid, G. E., & Black, D. S. (2012) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31825abfaa · Cited by 76
Psychological Approaches to Mental Illness
Peterson, C. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511984945.008 · Cited by 77
Social Support in a Virtual Community: Analysis of a Clinic-Affiliated Online Support Group for Persons Living with HIV/AIDS
Flickinger, T., DeBolt, C. L., Waldman, A. L., Reynolds, G., Cohn, W. F., Beach, M. C., Ingersoll, K. S., & Dillingham, R. (2016) · AIDS and Behavior · doi:10.1007/s10461-016-1587-3 · Cited by 76
Mental Health, Psychosocial Challenges and Resilience in Older Adults Living with HIV
Halkitis, P. N., Krause, K. D., & Vieira, D. L. (2016) · Interdisciplinary topics in gerontology and geriatrics · doi:10.1159/000448564 · Cited by 74
Cognitive behavioral therapy for body image and self-care (CBT-BISC) in sexual minority men living with HIV: A randomized controlled trial.
Blashill, A. J., Safren, S. A., Wilhelm, S., Jampel, J. D., Taylor, S. W., O’Cleirigh, C. M., & Mayer, K. H. (2017) · Health Psychology · doi:10.1037/hea0000505 · Cited by 75
The role of religion in HIV-positive women's disclosure experiences and coping strategies in Kinshasa, Democratic Republic of Congo
Maman, S., Cathcart, R., Burkhardt, G., Omba, S., & Behets, F. (2009) · Social Science & Medicine · doi:10.1016/j.socscimed.2008.12.028 · Cited by 72
Self-reported sleep disturbance is associated with lower CD4 count and 24-h urinary dopamine levels in ethnic minority women living with HIV
Seay, J. S., McIntosh, R., Fekete, E. M., Fletcher, M. A., Kumar, M., Schneiderman, N., & Antoni, M. H. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.06.022 · Cited by 70
Discrimination, Medical Distrust, Stigma, Depressive Symptoms, Antiretroviral Medication Adherence, Engagement in Care, and Quality of Life Among Women Living With HIV in North Carolina: A Mediated Structural Equation Model
Relf, M. V., Pan, W., Edmonds, A., Ramirez, C. B., Amarasekara, S., & Adimora, A. A. (2019) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000002033 · Cited by 76
Gender and Age Differences in Quality of Life and the Impact of Psychopathological Symptoms Among HIV-Infected Patients
Pereira, M., & Canavarro, M. C. (2011) · AIDS and Behavior · doi:10.1007/s10461-011-9928-8 · Cited by 70
Childhood Trauma and Health Outcomes in HIV-Infected Patients
Pence, B. W., Mugavero, M. J., Carter, T., Leserman, J., Thielman, N. M., Raper, J. L., Proeschold‐Bell, R. J., Reif, S., & Whetten, K. (2011) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31824150bb · Cited by 71
Self-citation
Marital Status and Mental Health
Williams, K., Frech, A., & Carlson, D. L. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511984945.020 · Cited by 70
A Conceptual Framework for Understanding Chronic Pain in Patients with HIV
Merlin, J. S., Zinski, A., Norton, W. E., Ritchie, C. S., Saag, M. S., Mugavero, M. J., Treisman, G. J., & Hooten, W. M. (2013) · Pain Practice · doi:10.1111/papr.12052 · Cited by 71
Pathogen–Host Defense in the Evolution of Depression: Insights into Epidemiology, Genetics, Bioregional Differences and Female Preponderance
Raison, C. L., & Miller, A. H. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.194 · Cited by 71
Mindfulness-Based Interventions for Adults Living with HIV/AIDS: A Systematic Review and Meta-analysis
Scott-Sheldon, L. A. J., Balletto, B. L., Donahue, M. L., Feulner, M. M., Cruess, D. G., Salmoirago-Blotcher, E., Wing, R. R., & Carey, M. P. (2019) · AIDS and Behavior · doi:10.1007/s10461-018-2236-9 · Cited by 68
Neuropsychiatric complications of aging with HIV
Watkins, C. C., & Treisman, G. J. (2012) · Journal of NeuroVirology · doi:10.1007/s13365-012-0108-z · Cited by 64
‘I was thinking too much’: experiences of HIV ‐positive adults with common mental disorders and poor adherence to antiretroviral therapy in Zimbabwe
Kidia, K. K., Machando, D., Bere, T. C., Macpherson, K., Nyamayaro, P. C., Potter, L., Makadzange, T., Munjoma, R., Marufu, M., Araya, R., et al. (2015) · Tropical Medicine & International Health · doi:10.1111/tmi.12502 · Cited by 74
Social Support as a Key Protective Factor against Depression in HIV-Infected Patients: Report from large HIV clinics in Hanoi, Vietnam
Matsumoto, S., Yamaoka, K., Takahashi, K., Tanuma, J., Mizushima, D., Duy, C., Nguyen, D. T., Nguyen, H. D. T., Nguyen, K. V., & Oka, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-15768-w · Cited by 68
Prevalence of Depressive Symptoms and Associated Factors among HIV-Positive Youth Attending ART Follow-Up in Addis Ababa, Ethiopia
Kurbi, H. A., Shumet, S., Nassir, Z., Agidew, M., & Angaw, D. A. (2019) · AIDS Research and Treatment · doi:10.1155/2019/4610458 · Cited by 66

Authors: Leserman, J.
Affiliations: University of North Carolina at Chapel Hill (US)
Corresponding author: Leserman, Jane
Venue: Psychosomatic Medicine
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2008-06
Volume: 70
Issue: 5
Pages: 539-545
ISSN: 0033-3174 (ISSN-L)
DOI: 10.1097/psy.0b013e3181777a5f
OpenAlex: W2018119542
Cited by: 662
References: 63
Citations by year: 2026: 6 · 2025: 9 · 2024: 22 · 2023: 18 · 2022: 35 · 2021: 37 · 2020: 35 · 2019: 45 · 2018: 43 · 2017: 86 · 2016: 47 · 2015: 35 · 2014: 38 · 2013: 44 · 2012: 50
FWCI: 4.28
Type: journal article
Language: en
Open access: closed
Locations: Psychosomatic Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: National Center for Complementary and Integrative Health (R01AT002035)
Topics: Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Keywords: HIV disease progression, depression, stress, trauma, life events, CD4 count, viral load, clinical deterioration, mortality, psychoneuroimmunology, highly active antiretroviral therapy, psychosocial interventions
MeSH terms: Depressive Disorder, Health Services Needs and Demand, Humans, Life Change Events, Longitudinal Studies, Patient Care Team, Patient Compliance, Psychoneuroimmunology, Risk Factors, Stress, Psychological, HIV Infections, Comorbidity, Disease Progression, CD4 Lymphocyte Count, Viral Load, Antiretroviral Therapy, Highly Active

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Role of Depression, Stress, and Trauma in HIV Disease Progression

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks