Cited by 28Stress Responses and CortisolHealth disparities and outcomesHealth, psychology, and well-being

Associations Between Health-Related Self-Protection, Diurnal Cortisol, and C-Reactive Protein in Lonely Older Adults

Abstract

Objectives The aim of this study was to examine whether health-related self-protection (e.g., using positive reappraisals or avoiding self-blame) prevents lonely older adults from exhibiting increases in diurnal cortisol secretion and higher levels of C-reactive protein (CRP). Methods This longitudinal study (n = 122) examined diurnal cortisol levels (area under the curve) at baseline and 2-year follow-up. Levels of CRP were measured at 6-year follow-up. The main predictors included baseline levels of loneliness and health-related self-protection. Results Among lonely participants, baseline self-protection predicted an amelioration of 2-year increases in diurnal cortisol volume (β = -.34, p = .03) and lower levels of CRP at 6-year follow-up (β = -.42, p = .006). These significant associations were not found among nonlonely participants (β Conclusions These findings suggest that lonely older adults may ameliorate biologic disturbances if they engage in self-protection to cope with their health threats.

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Crossref · 10.1097/psy.0b013e3182732dc6

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Research works printed but not linked: 38

  1. Hawkley, 2007, Aging and loneliness: downhill quickly Curr Dir Psychol S, ci, 16, 187
  2. Heckhausen, 2010, A motivational theory of life-span development., Psychol Rev, 117, 32, 10.1037/a0017668 · DOI · Paper page
  3. Wrosch, 2009, Cortisol secretion and functional disabilities in old age: importance of using adaptive control strategies., Psychosom Med, 71, 996, 10.1097/PSY.0b013e3181ba6cd1 · DOI
  4. Kiecolt-Glaser, 1984, Urinary cortisol levels, cellular immunocompetency, and loneliness in psychiatric inpatients., Psychosom Med, 46, 15, 10.1097/00006842-198401000-00004 · DOI · Paper page
  5. Russell, 1997, Loneliness and nursing home admission among rural older adults., Psychol Aging, 12, 574, 10.1037/0882-7974.12.4.574 · DOI
  6. Seeman, 2000, Health promoting effects of friends and family on health outcomes in older adults., Am J Health Promot, 14, 362, 10.4278/0890-1171-14.6.362 · DOI · Paper page
  7. Sugisawa, 1994, Social networks, social support, and mortality among older people in Japan., J Gerontol, 49, 3, 10.1093/geronj/49.1.S3 · DOI · Paper page
  8. Cacioppo, 2005, Sociality, spirituality, and meaning making: Chicago health, aging, and social relations study., Rev Gen Psychol, 9, 143, 10.1037/1089-2680.9.2.143 · DOI
  9. Cacioppo, 2000, Lonely traits and concomitant physiological processes: the MacArthur social neuroscience studies., Int J Psychophysiol, 35, 143, 10.1016/S0167-8760(99)00049-5 · DOI · Paper page
  10. Cacioppo, 2002, Do lonely days invade the nights Potential social modulation of sleep efficiency., Psychol Sci, 13, 384, 10.1111/j.0956-7976.2002.00469.x · DOI · Paper page
  11. Mahon, 2001, Mental health variables and positive health practices in early adolescents., Psychol Rep, 88, 1023, 10.2466/pr0.2001.88.3c.1023 · DOI
  12. Ridker, 2002, Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events., N Engl J Med, 347, 1557, 10.1056/NEJMoa021993 · DOI · Paper page
  13. Kuo, 2006, Linking C-reactive protein to late-life disability in the National Health and Nutrition Examination Survey (NHANES) 1999-2002., J Gerontol A Biol Sci Med Sci, 61, 380, 10.1093/gerona/61.4.380 · DOI · Paper page
  14. Jenny, 2007, Inflammation biomarkers and near-term death in older men., Am J Epidemiol, 165, 684, 10.1093/aje/kwk057 · DOI
  15. Ridker, 2008, Inflammation, C-reactive protein, and atherothrombosis., J Periodontol, 79, 1544, 10.1902/jop.2008.080249 · DOI
  16. Strandberg, 2000, C-reactive protein, cardiovascular risk factors, and mortality in a prospective study in the elderly., Arteriosclerosis, 20, 1057, 10.1161/01.ATV.20.4.1057 · DOI
  17. Wrosch, 2004, Health stresses and depressive symptomatology in the elderly., Curr Dir Psychol Sci, 13, 17, 10.1111/j.0963-7214.2004.01301005.x · DOI
  18. Lockenhoff, 2004, Socioemotional selectivity theory, aging, and health: the increasingly delicate balance between regulating emotions and making tough choices., J Pers, 72, 1393, 10.1111/j.1467-6494.2004.00301.x · DOI
  19. Wrosch, 2000, Primary and secondary control strategies for managing health and financial stress across adulthood., Psychol Aging, 15, 387, 10.1037/0882-7974.15.3.387 · DOI
  20. Wheaton, 1985, Models for the stress-buffering functions of coping resources., J Health Soc Behav, 26, 352, 10.2307/2136658 · DOI
  21. Wrosch, 2007, Physical health problems, depressive mood, and cortisol secretion in old age: buffer effects of health engagement control strategies., Health Psychol, 26, 341, 10.1037/0278-6133.26.3.341 · DOI
  22. Wrosch, 2002, Perceived control of life regrets: good for young and bad for old adults., Psychol Aging, 17, 340, 10.1037/0882-7974.17.2.340 · DOI
  23. Prince, 1997, Social support deficits, loneliness and life events as risk factors for depression in old age. The Gospel Oak Project VI., Psychol Med, 27, 323, 10.1017/S0033291796004485 · DOI
  24. Sarason, 1981, Assessing social support: the social support questionnaire., J Pers Soc Psychol, 44, 127, 10.1037/0022-3514.44.1.127 · DOI · Paper page
  25. Clements, 1998, The relationship between salivary cortisol concentrations in frozen versus mailed samples., Psychoneuroendocrinology, 23, 613, 10.1016/S0306-4530(98)00031-6 · DOI
  26. Dressendorfer, 1992, Synthesis of a cortisol-biotin conjugate and evaluation as a tracer in an immunoassay for salivary cortisol measurement., J Steroid Biochem Mol Biol, 43, 683, 10.1016/0960-0760(92)90294-S · DOI · Paper page
  27. McDade, 2004, High-sensitivity enzyme immunoassay for C-reactive protein in dried blood spots., Clin Chem, 50, 652, 10.1373/clinchem.2003.029488 · DOI
  28. Williams, 2009, The use of dried blood spot sampling in the national social life, health, and aging project., J Gerontol B Psychol Sci Soc Sci, 64, 131, 10.1093/geronb/gbn022 · DOI
  29. Adler, 2000, Relationship of subjective and objective social status with psychological and physiological functioning: preliminary data in healthy, white women., Health Psychol, 19, 586, 10.1037/0278-6133.19.6.586 · DOI · Paper page
  30. Preacher, 2008, Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models., Behav Res Methods, 40, 879, 10.3758/BRM.40.3.879 · DOI · Paper page
  31. Carstensen, 1999, Taking time seriously: a theory of socioemotional selectivity., Am Psychol, 54, 165, 10.1037/0003-066X.54.3.165 · DOI · Paper page
  32. Chrousos, 1992, The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis., JAMA, 267, 1244, 10.1001/jama.1992.03480090092034 · DOI · Paper page
  33. Raison, 2003, When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders., Am J Psychiatry, 160, 1554, 10.1176/appi.ajp.160.9.1554 · DOI · Paper page
  34. Hotamisligil, 2006, Inflammation and metabolic disorders., Nature, 444, 860, 10.1038/nature05485 · DOI · Paper page
  35. Scrivo, 2011, Inflammation as common soil of the multifactorial diseases., Autoimmun Rev, 10, 369, 10.1016/j.autrev.2010.12.006 · DOI
  36. Miller, 1997, Social relationships and immune processes in HIV seropositive gay and bisexual men., Ann Behav Med, 19, 139, 10.1007/BF02883331 · DOI · Paper page
  37. Gunthert, 1999, The role of neuroticism in daily stress and coping., J Pers Soc Psychol, 77, 1087, 10.1037/0022-3514.77.5.1087 · DOI
  38. Portella, 2005, Enhanced early morning salivary cortisol in neuroticism., Am J Psychiatry, 162, 807, 10.1176/appi.ajp.162.4.807 · DOI

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Sorted by citations

Authors
Rueggeberg, R., Wrosch, C., Miller, G. E., & McDade, T. W.
Affiliations
  • Concordia University (CA)
  • Northwestern University (US)
Corresponding author
Wrosch, Carsten
Venue
Psychosomatic Medicine
Published
2012-11
Volume
74
Issue
9
Pages
937-944
ISSN
0033-3174 (ISSN-L)
OpenAlex
W1987853702
Cited by
28
References
15
Citations by year
2026: 1 · 2024: 2 · 2023: 4 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 1 · 2016: 3 · 2015: 2 · 2014: 5 · 2013: 3
FWCI
1.33
Type
journal article
Language
en
Open access
closed
Locations
  • Psychosomatic Medicine (publishedVersion)
  • PubMed (publishedVersion)
Funders
Canadian Institutes of Health Research (89736)
Topics
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
  • Social Sciences › Health › Health disparities and outcomes
  • Health Sciences › Health Professions › General Health Professions › Health, psychology, and well-being
Keywords
loneliness, older adults, diurnal cortisol, C-reactive protein, positive reappraisal, self-blame, stress buffering, mediation, physiological stress response, inflammation
MeSH terms
Adaptation, Psychological, Aged, Aged, 80 and over, Aging, Attitude to Health, C-Reactive Protein, Chronic Disease, Circadian Rhythm, Culture, Female, Humans, Hydrocortisone, Loneliness, Longitudinal Studies, Male, Middle Aged, Motivation, Problem Solving, Quality of Life, Surveys and Questionnaires, Self Care, Self Concept, Social Support, Health Behavior

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