Associations Between Health-Related Self-Protection, Diurnal Cortisol, and C-Reactive Protein in Lonely Older Adults
Abstract
Objectives The aim of this study was to examine whether health-related self-protection (e.g., using positive reappraisals or avoiding self-blame) prevents lonely older adults from exhibiting increases in diurnal cortisol secretion and higher levels of C-reactive protein (CRP). Methods This longitudinal study (n = 122) examined diurnal cortisol levels (area under the curve) at baseline and 2-year follow-up. Levels of CRP were measured at 6-year follow-up. The main predictors included baseline levels of loneliness and health-related self-protection. Results Among lonely participants, baseline self-protection predicted an amelioration of 2-year increases in diurnal cortisol volume (β = -.34, p = .03) and lower levels of CRP at 6-year follow-up (β = -.42, p = .006). These significant associations were not found among nonlonely participants (β Conclusions These findings suggest that lonely older adults may ameliorate biologic disturbances if they engage in self-protection to cope with their health threats.
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Negative cognitive appraisals and neural sensitivity to social threat have been associated with inflammation and depression.
“neurocognitive mechanisms like negative cognitive appraisals and neural sensitivity to social threat, which have been associated with inflammation and depression”
From From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. (2014) · cites this paper as Rueggeberg, Wrosch, Miller, & McDade, 2012
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Slavich, G. M., & Irwin, M. R. (2014) · Psychological Bulletin · doi:10.1037/a0035302 · Cited by 2,206 · see citing works
- Authors
- Rueggeberg, R., Wrosch, C., Miller, G. E., & McDade, T. W.
- Affiliations
- Concordia University (CA)
- Northwestern University (US)
- Corresponding author
- Wrosch, Carsten
- Venue
- Psychosomatic Medicine
- Published
- 2012-11
- Volume
- 74
- Issue
- 9
- Pages
- 937-944
- ISSN
- 0033-3174 (ISSN-L)
- OpenAlex
- W1987853702
- Cited by
- 28
- References
- 15
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 4 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 1 · 2016: 3 · 2015: 2 · 2014: 5 · 2013: 3
- FWCI
- 1.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychosomatic Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research (89736)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Social Sciences › Health › Health disparities and outcomes
- Health Sciences › Health Professions › General Health Professions › Health, psychology, and well-being
- Keywords
- loneliness, older adults, diurnal cortisol, C-reactive protein, positive reappraisal, self-blame, stress buffering, mediation, physiological stress response, inflammation
- MeSH terms
- Adaptation, Psychological, Aged, Aged, 80 and over, Aging, Attitude to Health, C-Reactive Protein, Chronic Disease, Circadian Rhythm, Culture, Female, Humans, Hydrocortisone, Loneliness, Longitudinal Studies, Male, Middle Aged, Motivation, Problem Solving, Quality of Life, Surveys and Questionnaires, Self Care, Self Concept, Social Support, Health Behavior
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