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Cited by 142Autism Spectrum Disorder ResearchChild Nutrition and Feeding IssuesAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

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An update on anxiety in youth with autism spectrum disorders

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Vasa, Roma A., Mazurek, Micah O.·2015·Current Opinion in Psychiatry
DOI 10.1097/yco.0000000000000133PMC PMC5764108
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Abstract

PURPOSE OF REVIEW: Anxiety is one of the most common co-occurring psychiatric conditions in youth with autism spectrum disorders (ASDs). This article reviews recent evidence as well as earlier relevant studies regarding the characteristics, assessment, and treatment of anxiety in youth with ASD. RECENT FINDINGS: It is well established that the prevalence of anxiety in youth with an ASD is significantly greater than the prevalence of anxiety in the general population. Recent studies have highlighted the importance of informant, method, and instrument when measuring anxiety in this population. Despite the high prevalence, findings to date have been unable to identify any consistent risk factors for anxiety. New psychological treatments, including modified cognitive behavioral therapy for youth with high functioning ASD and co-occurring anxiety, are emerging. Pharmacological data, however, are scant. Existing studies show that youth with ASD are at increased risk for behavioral activation when taking SSRIs. SUMMARY: Clinicians working with youth with ASD are encouraged to routinely screen for anxiety. Until further data are available, clinical judgment is needed when prescribing treatments, particularly selective serotonin reuptake inhibitors, which require close monitoring of side-effects. Research on risk factors, pathophysiology, and treatment of this condition is needed.

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Metadata

Authors
Vasa, R. A., & Mazurek, M. O.
Affiliations
  • Kennedy Krieger Institute (US)
  • University of Missouri (US)
Corresponding author
Vasa, Roma A.
ORCID
Venue
Current Opinion in Psychiatry
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2015-03
Volume
28
Issue
2
Pages
83-90
ISSN
0951-7367 (ISSN-L)
DOI
10.1097/yco.0000000000000133
PMC
PMC5764108
OpenAlex
W2021041873
Cited by
142
References
23
Citations by year
2026: 16 · 2025: 20 · 2024: 12 · 2023: 12 · 2022: 13 · 2021: 27 · 2020: 10 · 2019: 10 · 2018: 5 · 2017: 9 · 2016: 5 · 2015: 2
FWCI
0.69
Type
journal article
Language
en
Open access
Locations
  • Current Opinion in Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institute of Mental Health (R34MH104337, R21MH100268)
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (R03HD081070)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
autism spectrum disorder, anxiety, youth, psychiatric comorbidity, anxiety prevalence, anxiety assessment, informant effects, risk factors, cognitive behavioral therapy, selective serotonin reuptake inhibitors, behavioral activation, pharmacotherapy, screening
MeSH terms
Adolescent, Anxiety, Child, Child Development Disorders, Pervasive, Humans

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