A functional and structural study of emotion and face processing in children with autism
Open accessAbstract
Children with autism exhibit impairment in the processing of socioemotional information. The amygdala, a core structure centrally involved in socioemotional functioning, has been implicated in the neuropathology of autism. We collected structural and functional magnetic resonance images (MRI) in children 8 to 12 years of age with high-functioning autism (n=12) and typical development (n=15). The functional MRI experiment involved matching facial expressions and people. Volumetric analysis of the amygdala was also performed. The results showed that children with autism exhibited intact emotion matching, while showing diminished activation of the fusiform gyrus (FG) and the amygdala. Conversely, the autism group showed deficits in person matching amidst some FG and variable amygdala activation. No significant between-group differences in the volume of the left or right amygdala were found. There were associations between age, social anxiety and amygdala volume in the children with autism such that smaller volumes were generally associated with more anxiety and younger age. In summary, the data are consistent with abnormalities in circuits involved in emotion and face processing reported in studies of older subjects with autism showing reductions in amygdala activation related to emotion processing and reduced fusiform activation involved in face processing.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Numerous imaging studies show reduced activation in the fusiform face area in individuals with autism spectrum disorder.
“numerous imaging studies have shown reduced activation in the fusiform face area (FFA) in individuals with ASD (Corbett et al., 2009; Hubl et al., 2003; Pierce et al., 2001)”
From Behavioral, Perceptual, and Neural Alterations in Sensory and Multisensory Function in Autism Spectrum Disorder (2015) · cites this paper as Corbett et al., 2009
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482 · see citing works
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798 · see citing works
Lord, C., Rutter, M., & Le Couteur, A. (1994) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02172145 · Cited by 9,065 · see citing works
The fusiform face area: a module in human extrastriate cortex specialized for face perception
Kanwisher, N., McDermott, J., & Chun, M. M. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-11-04302.1997 · Cited by 7,738 · see citing works
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565 · see citing works
Wechsler Abbreviated Scale of Intelligence
Dumont, R., Willis, J. O., Veizel, K., & Zibulsky, J. (2014) · Wiley eBooks · doi:10.1002/9781118660584.ese2519 · Cited by 5,547 · see citing works
Maldjian, J., Laurienti, P., Kraft, R., & Burdette, J. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00169-1 · Cited by 5,453 · see citing works
Thresholding of statistical maps in functional neuroimaging using the false discovery rate
Genovese, C. R., Lazar, N. A., & Nichols, T. (2002) · NeuroImage · doi:10.1006/nimg.2001.1037 · Cited by 4,923 · see citing works
Wechsler Abbreviated Scale of Intelligence
Wechsler, D. (1999) · PsycTESTS Dataset · doi:10.1037/t15170-000 · Cited by 4,681 · see citing works
Minnesota studies in the philosophy of science
Feigl, H., & Scriven, M. (1956) · Cited by 4,419 · see citing works
The Emotional Brain: The Mysterious Underpinnings of Emotional Life
LeDoux, J. E. (2004) · Medical Entomology and Zoology · Cited by 4,212 · see citing works
Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress
Tsigos, C., & Chrousos, G. P. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(02)00429-4 · Cited by 2,822 · cited 2× · see citing works
“…that the amygdala, a brain structure involved in the processing of emotions (Adolphs et al., 2002), novelty (Schwartz et al., 2003), stress (Tsigos and Chrousos, 2002), anxiety (Davis, 1992), eye gaze (Spezio et al., 2007), orienting (Moses et al., 2002; Wright et al., 2003), and empathy…”
The Multidimensional Anxiety Scale for Children (MASC): factor structure, reliability, and validity
MARCH, J. S., PARKER, J. D. A., SULLIVAN, K., STALLINGS, P., & CONNERS, C. K. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199704000-00019 · Cited by 2,236 · see citing works
Klin, A., Jones, W., Schultz, R., Volkmar, F., & Cohen, D. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.9.809 · Cited by 2,120 · see citing works
Frackowiak, R. S. J. (1997) · Cited by 1,713 · see citing works
Functional neuroanatomy of face and object processing. A positron emission tomography study.
Sergent, J., Ohta, S., & Macdonald, B. (1992) · Brain : a journal of neurology · doi:10.1093/brain/115.1.15 · Cited by 1,576 · see citing works
Gaze fixation and the neural circuitry of face processing in autism
Dalton, K. M., Nacewicz, B. M., Johnstone, T., Schaefer, H. S., Gernsbacher, M. A., Goldsmith, H. H., Alexander, A. L., & Davidson, R. J. (2005) · Nature Neuroscience · doi:10.1038/nn1421 · Cited by 1,543 · see citing works
The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction.
Aggleton, J. P. (1992) · Wiley-Liss eBooks · Cited by 1,536 · see citing works
The neurobiology of social cognition
Adolphs, R. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00202-6 · Cited by 1,432 · see citing works
Expertise for cars and birds recruits brain areas involved in face recognition
Gauthier, I., Skudlarski, P., Gore, J. C., & Anderson, A. W. (2000) · Nature Neuroscience · doi:10.1038/72140 · Cited by 1,418 · cited 2× · see citing works
“obtained a level of perceptual expertise (Gauthier et al., 2000; Kanwisher et al., 1997; Kanwisher et al., 1999).”
Social intelligence in the normal and autistic brain: An fMRI study
Baron‐Cohen, S., Ring, H. A., Wheelwright, S., Bullmore, E. T., Brammer, M. J., Simmons, A., & Williams, S. C. R. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00621.x · Cited by 1,320 · see citing works
The amygdala: Neurobiological aspects of emotion, memory and mental dysfunction
Scheel-Krüger, J. (1993) · Journal of Chemical Neuroanatomy · doi:10.1016/0891-0618(93)90037-5 · Cited by 1,277 · see citing works
Diagnostic and Statistical Manual of Mental Disorders
Preedy, V., & Watson, R. (2010) · Springer eBooks · doi:10.1007/978-0-387-78665-0_5485 · Cited by 1,146 · see citing works
Baron-Cohen, S., Ring, H. A., Bullmore, E. T., Wheelwright, S., Ashwin, C., & Williams, S. C. R. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00011-7 · Cited by 1,130 · see citing works
Face-specific processing in the human fusiform gyrus
McCarthy, G., Puce, A., Gore, J. C., & Allison, T. (1997) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1997.9.5.605 · Cited by 1,127 · see citing works
Distinct spatial frequency sensitivities for processing faces and emotional expressions
Vuilleumier, P., Armony, J. L., Driver, J., & Dolan, R. J. (2003) · Nature Neuroscience · doi:10.1038/nn1057 · Cited by 1,117 · see citing works
Schultz, R. T. (2005) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2004.12.012 · Cited by 1,071 · see citing works
Haxby, J., Horwitz, B., Ungerleider, L. G., Maisog, J. M., Pietrini, P., & Grady, C. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-11-06336.1994 · Cited by 1,065 · see citing works
Social Intelligence in the Normal and Autistic Brain: An fMRI Study
Baron‐Cohen, S., RING, H. A., Wheelwright, S. J., Bullmore, E. T., Brammer, M. J., Simmons, A., & Williams, S. (2002) · The MIT Press eBooks · doi:10.7551/mitpress/3077.003.0028 · Cited by 1,044 · see citing works
Vӧllm, B., Taylor, A. N. W., Richardson, P., Corcoran, R., Stirling, J., McKie, S., Deakin, J. F. W., & Elliott, R. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.07.022 · Cited by 1,010 · see citing works
Schultz, R. T., Gauthier, I., Klin, A., Fulbright, R. K., Anderson, A. W., Volkmar, F., Skudlarski, P., Lacadie, C., Cohen, D. J., & Gore, J. C. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.4.331 · Cited by 1,000 · see citing works
Histoanatomic observations of the brain in early infantile autism
Bauman, M., & Kemper, T. L. (1985) · Neurology · doi:10.1212/wnl.35.6.866 · Cited by 964 · see citing works
Brain structural abnormalities in young children with autism spectrum disorder
Sparks, B. F., Friedman, S. D., Shaw, D. W., Aylward, E. H., Echelard, D., Artru, A. A., Maravilla, K. R., Giedd, J. N., Munson, J., Dawson, G., et al. (2002) · Neurology · doi:10.1212/wnl.59.2.184 · Cited by 961 · see citing works
Wojnar, L. (1998) · Cited by 912 · see citing works
Face processing occurs outside the fusiform ‘face area’ in autism: evidence from functional MRI
Pierce, K. (2001) · Brain · doi:10.1093/brain/124.10.2059 · Cited by 898 · see citing works
LeDoux, J. E. (1994) · Scientific American · doi:10.1038/scientificamerican0694-50 · Cited by 892 · see citing works
Social Communication Questionnaire
Snow, A. V. (2013) · Springer eBooks · doi:10.1007/978-1-4419-1698-3_1651 · Cited by 880 · see citing works
Schumann, C. M., Hamstra, J., Goodlin-Jones, B. L., Lotspeich, L. J., Kwon, H., Buonocore, M. H., Lammers, C. R., Reiss, A. L., & Amaral, D. G. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1297-04.2004 · Cited by 840 · see citing works
The functional neuroanatomy of social behaviour
Critchley, H. D., Daly, E. M., Bullmore, E. T., Williams, S. C. R., Van Amelsvoort, T., Robertson, D. M., Rowe, A., Phillips, M., McAlonan, G., Howlin, P., et al. (2000) · Brain · doi:10.1093/brain/123.11.2203 · Cited by 816 · see citing works
Involvement of the amygdala in memory storage: Interaction with other brain systems
McGaugh, J. L., Cahill, L. F., & Roozendaal, B. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.13508 · Cited by 747 · see citing works
Abnormal Processing of Social Information from Faces in Autism
Adolphs, R., Sears, L. L., & Piven, J. (2001) · Journal of Cognitive Neuroscience · doi:10.1162/089892901564289 · Cited by 590 · see citing works
Neuropathology of Infantile Autism
Kemper, T. L., & Bauman, M. (1998) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199807000-00001 · Cited by 585 · see citing works
Face recognition in human extrastriate cortex.
Allison, T., Ginter, H., McCarthy, G., Nobre, A. C., Puce, A., Luby, M., & Spencer, D. D. (1994) · Journal of Neurophysiology · doi:10.1152/jn.1994.71.2.821 · Cited by 567 · see citing works
Inhibited and uninhibited infants “grown up”: adult amygdalar response to novelty
Schwartz, C. E., Wright, C. I., Shin, L. M., Kagan, J., & Rauch, S. L. (2003) · Science · doi:10.1126/science.1083703 · Cited by 528 · see citing works
MRI volumes of amygdala and hippocampus in non–mentally retarded autistic adolescents and adults
Aylward, E., Minshew, N. J., Goldstein, G., Honeycutt, N. A., Augustine, A. M., Yates, K. O., Barta, P. E., & Pearlson, G. D. (1999) · Neurology · doi:10.1212/wnl.53.9.2145 · Cited by 513 · see citing works
Impaired Recognition of Social Emotions following Amygdala Damage
Adolphs, R., Baron-Cohen, S., & Tranel, D. (2002) · Journal of Cognitive Neuroscience · doi:10.1162/089892902760807258 · Cited by 510 · see citing works
The neuroanatomy of autism: a voxel-based whole brain analysis of structural scans
Abell, F., Krams, M., Ashburner, J., Passingham, R., Friston, K., Frackowiak, R., Happé, F., Frith, C., & Frith, U. (1999) · NeuroReport · doi:10.1097/00001756-199906030-00005 · Cited by 480 · see citing works
Convergent neuroanatomical and behavioural evidence of an amygdala hypothesis of autism
Howard, M. A., Cowell, P. E., Boucher, J., Broks, P., Mayes, A. R., Farrant, A., & Roberts, N. P. (2000) · Neuroreport · doi:10.1097/00001756-200009110-00020 · Cited by 479 · see citing works
Effective Connectivity within the Distributed Cortical Network for Face Perception
Fairhall, S. L., & Ishai, A. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhl148 · Cited by 471 · see citing works
The brain response to personally familiar faces in autism: Findings of fusiform activity and beyond
Pierce, K. (2004) · Brain · doi:10.1093/brain/awh289 · Cited by 432 · see citing works
The role of the amygdala in fear-potentiated startle: implications for animal models of anxiety
Davis, M. (1992) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(92)90014-w · Cited by 427 · see citing works
The Understanding of the Emotional Meaning of Facial Expressions in People with Autism
Celani, G., Battacchi, M. W., & Arcidiacono, L. (1999) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1025970600181 · Cited by 426 · see citing works
Stereological Analysis of Amygdala Neuron Number in Autism
Schumann, C. M., & Amaral, D. G. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1285-06.2006 · Cited by 413 · see citing works
The orbitofrontal-amygdala circuit and self-regulation of social-emotional behavior in autism
Bachevalier, J., & Loveland, K. A. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.07.002 · Cited by 402 · see citing works
Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism
Courchesne, E. (1997) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(97)80016-5 · Cited by 401 · see citing works
Learning and Cognition in Autism
Schopler, E., & Mesibov, G. B. (1995) · Springer eBooks · doi:10.1007/978-1-4899-1286-2 · Cited by 400 · see citing works
Ashwin, C., Baron‐Cohen, S., Wheelwright, S. J., O’Riordan, M., & Bullmore, E. T. (2006) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.04.014 · Cited by 382 · see citing works
Comorbid anxiety symptoms in children with pervasive developmental disorders
Muris, P., Steerneman, P., Merckelbach, H., Holdrinet, I., & Meesters, C. (1998) · Journal of Anxiety Disorders · doi:10.1016/s0887-6185(98)00022-x · Cited by 368 · see citing works
Wang, A. T., Dapretto, M., Hariri, A. R., Sigman, M., & Bookheimer, S. Y. (2004) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200404000-00015 · Cited by 364 · see citing works
Activation of the fusiform gyrus when individuals with autism spectrum disorder view faces
Hadjikhani, N. K., Joseph, R. M., Snyder, J., Chabris, C. F., Clark, J., Steele, S. D., McGrath, L. M., Vangel, M. G., Aharon, I., Feczko, E., et al. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.03.025 · Cited by 350 · see citing works
Face Perception in Children with Autism and Asperger's Syndrome
Davies, S., Bishop, D., Manstead, A. S. R., & Tantam, D. (1994) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1994.tb01808.x · Cited by 325 · see citing works
Facial Expressions of Affect in Autistic, Mentally Retarded and Normal Children
Yirmiya, N., Kasari, C. L., Sigman, M., & Mundy, P. (1989) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1989.tb00785.x · Cited by 323 · see citing works
A pilot study of amygdala volumes in pediatric generalized anxiety disorder
De Bellis, M. D., Casey, B. J., Dahl, R. E., Birmaher, B., Williamson, D. E., Thomas, K. M., Axelson, D. A., Frustaci, K., Boring, A. M., Hall, J., et al. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00835-0 · Cited by 322 · cited 2× · see citing works
“…seem counterintuitive, however, since larger amygdala volumes in children and adolescents with generalized anxiety disorder have been reported (De Bellis et al., 2000); recently, smaller amygdala volumes have been shown in childrenwith pediatric anxiety using voxel-based morphometry (Milham et…”
Understanding emotions from standardized facial expressions in autism and normal development
Castelli, F. (2005) · Autism · doi:10.1177/1362361305056082 · Cited by 317 · see citing works
Robb, R. A., Hanson, D. P., Karwoski, R. A., Larson, A. G., Workman, E. L., & Stacy, M. C. (1989) · Computerized Medical Imaging and Graphics · doi:10.1016/0895-6111(89)90285-1 · Cited by 315 · see citing works
Yoon, J. H., Minzenberg, M., Ursu, S., Walters, R., Wendelken, C., Ragland, J. D., & Carter, C. S. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.07060945 · Cited by 315 · see citing works
Self-citationTHE AUTISTIC CHILD'S APPRAISAL OF EXPRESSIONS OF EMOTION: A FURTHER STUDY
Hobson, R. P. (1986) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1986.tb00191.x · Cited by 313 · see citing works
Amygdala Volume and Nonverbal Social Impairment in Adolescent and Adult Males With Autism
Nacewicz, B. M., Dalton, K. M., Johnstone, T., Long, M. T., McAuliff, E. M., Oakes, T. R., Alexander, A. L., & Davidson, R. J. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.12.1417 · Cited by 287 · see citing works
Emotion recognition in autism: coordinating faces and voices
Hobson, R. P., Ouston, J., & Lee, A. (1988) · Psychological Medicine · doi:10.1017/s0033291700009843 · Cited by 283 · see citing works
The fusiform face area is selective for faces not animals
Kanwisher, N., Stanley, D. A., & Harris, A. M. (1999) · Neuroreport · doi:10.1097/00001756-199901180-00035 · Cited by 269 · see citing works
Amygdala Automaticity in Emotional Processing
DOLAN, R. J., & VUILLEUMIER, P. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb07093.x · Cited by 263 · see citing works
Cortisol circadian rhythms and response to stress in children with autism
Corbett, B. A., Mendoza, S., Abdullah, M., Wegelin, J. A., & Levine, S. (2006) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2005.05.011 · Cited by 258 · see citing works
Self-citationRecognition and Expression of Emotional Cues by Autistic and Normal Adults
Macdonald, H., Rutter, M. L., Howlin, P., Rios, P., Conteur, A. L., Evered, C., & Folstein, S. E. (1989) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1989.tb00288.x · Cited by 253 · see citing works
Dalton, K. M., Nacewicz, B. M., Alexander, A. L., & Davidson, R. J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.019 · Cited by 245 · see citing works
Avidan, G., Hasson, U., Malach, R., & Behrmann, M. (2005) · Journal of Cognitive Neuroscience · doi:10.1162/0898929054475145 · Cited by 232 · see citing works
Nuisance variables and the ex post facto design
Meehl, P. E. (1970) · University of Minnesota Digital Conservancy (University of Minnesota) · Cited by 220 · see citing works
Amygdala damage impairs eye contact during conversations with real people
Spezio, M. L., Huang, P.-Y. S., Castelli, F., & Adolphs, R. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3789-06.2007 · Cited by 213 · see citing works
Piggot, J., Kwon, H., Mobbs, D., Blasey, C., Lotspeich, L., Menon, V., Bookheimer, S., & Reiss, A. L. (2004) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200404000-00014 · Cited by 201 · see citing works
Amygdalar Volume and Behavioral Development in Autism
MUNSON, J. A., Dawson, G., Abbott, R., Faja, S., Webb, S. J., Friedman, S. D., Shaw, D., Artru, A. A., & Dager, S. R. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.6.686 · Cited by 191 · see citing works
Milham, M. P., Nugent, A. C., Drevets, W. C., Dickstein, D. S., Leibenluft, E., Ernst, M., Charney, D., & Pine, D. S. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.01.038 · Cited by 186 · see citing works
Intact recognition of emotional prosody following amygdala damage
Adolphs, R. (1999) · Neuropsychologia · doi:10.1016/s0028-3932(99)00023-8 · Cited by 162 · see citing works
Autism and family home movies: Preliminary findings
Adrien, J. L., Faure, M., Perrot, A., HAMEURY, L., Garreau, B., Barthélémy, C., & SAUVAGE, D. (1991) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02206996 · Cited by 158 · see citing works
Memory for Faces in Children with Autism
Hauck, M., FEIN, D. A., Maltby, N., Waterhouse, L. H., & Feinstein, C. (1998) · Child Neuropsychology · doi:10.1076/chin.4.3.187.3174 · Cited by 152 · see citing works
Variable cortisol circadian rhythms in children with autism and anticipatory stress
Corbett, B. A., Mendoza, S. P., Wegelin, J. A., Carmean, V., & Levine, S. D. (2008) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0823 · Cited by 149 · see citing works
Self-citationJuranek, J., Filipek, P. A., Berenji, G. R., Modahl, C., Osann, K., & Spence, M. A. (2006) · Journal of Child Neurology · doi:10.1177/7010.2006.00237 · Cited by 147 · see citing works
Wright, C. I., Martis, B., Schwartz, C., Shin, L. M., Fischer, H., McMullin, K. G., & Rauch, S. L. (2003) · NeuroImage · doi:10.1016/s1053-8119(02)00037-x · Cited by 139 · see citing works
Investigating individual differences in brain abnormalities in autism
Salmond, C. H., de Haan, M. D. H., Friston, K. J., Gadian, D. G., & Vargha‐Khadem, F. (2003) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2002.1210 · Cited by 115 · see citing works
Emotional neurophysiology of the amygdala within the context of human cognition.
Halgren, E. (1992) · Cited by 108 · see citing works
Finding a face in the crowd: Testing the anger superiority effect in Asperger Syndrome
Ashwin, C., Wheelwright, S. J., & Baron‐Cohen, S. (2006) · Brain and Cognition · doi:10.1016/j.bandc.2005.12.008 · Cited by 104 · see citing works
The Amygdala, Autism and Anxiety
Amaral, D. G., & Corbett, B. A. (2003) · Novartis Foundation symposium · doi:10.1002/0470869380.ch11 · Cited by 73 · see citing works
Self-citationDifferential involvement of amygdala and hippocampus in responding to novel objects and contexts.
Moses, S. N., Sutherland, R., & McDonald, R. (2002) · Brain Research Bulletin · doi:10.1016/s0361-9230(02)00820-1 · Cited by 53 · see citing works
Kamio, Y., Wolf, J. M., & FEIN, D. A. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-005-0056-z · Cited by 42 · see citing works
A RELATIONSHIP BETWEEN SMELL IDENTIFICATION AND EMPATHY
Spinella, M. (2002) · International Journal of Neuroscience · doi:10.1080/00207450290025680 · Cited by 42 · see citing works
Exploring the Neurofunctional Organization of Face Processing in Autism
Pierce, K., & Courchesne, E. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.4.344 · Cited by 27 · see citing works
Aggleton, J. P., Kentridge, R. W., & Sembi, S. (1992) · Behavioural Brain Research · doi:10.1016/s0166-4328(05)80146-9 · Cited by 24 · see citing works
Worsley (1996) · doi:10.1002/(sici)1097-0193(1996)4:1
Flagged first, then by citations
Research works printed but not linked: 1
- Aggleton JP The Amygdala 2000 Oxford University Press Oxford Second ed.
Cited by
Sorted by citations
Harms, M. B., Martin, A., & Wallace, G. L. (2010) · Neuropsychology Review · doi:10.1007/s11065-010-9138-6 · Cited by 1,028 · see citing works
Preference for geometric patterns early in life as a risk factor for autism
Pierce, K., Conant, D., Hazin, R., Stoner, R., & Desmond, J. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.113 · Cited by 486 · see citing works
Decreased interhemispheric functional connectivity in autism
Anderson, J. S., Druzgal, T. J., Froehlich, A., DuBray, M. B., Lange, N., Alexander, A. L., Abildskov, T., Nielsen, J. A., Cariello, A. N., Cooperrider, J. R., et al. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq190 · Cited by 438 · see citing works
Functional connectivity magnetic resonance imaging classification of autism
Anderson, J. S., Nielsen, J. A., Froehlich, A. L., DuBray, M. B., Druzgal, T. J., Cariello, A. N., Cooperrider, J. R., Zielinski, B. A., Ravichandran, C., Fletcher, P. T., et al. (2011) · Brain · doi:10.1093/brain/awr263 · Cited by 405 · see citing works
Baum, S. H., Stevenson, R. A., & Wallace, M. T. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.09.007 · Cited by 370 · see citing works
Review of neuroimaging in autism spectrum disorders: what have we learned and where we go from here
Anagnostou, E., & Taylor, M. J. (2011) · Molecular Autism · doi:10.1186/2040-2392-2-4 · Cited by 321 · see citing works
Reward circuitry function in autism spectrum disorders
Dichter, G. S., Felder, J. N., Green, S. R., Rittenberg, A. M., Sasson, N. J., & Bodfish, J. W. (2012) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsq095 · Cited by 296 · see citing works
The nature of brain dysfunction in autism: Functional brain imaging studies
Minshew, N. J., & Keller, T. A. (2010) · Current Opinion in Neurology · doi:10.1097/wco.0b013e32833782d4 · Cited by 291 · see citing works
Functional magnetic resonance imaging of autism spectrum disorders
Dichter, G. S. (2012) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2012.14.3/gdichter · Cited by 215 · see citing works
Structural and functional magnetic resonance imaging of autism spectrum disorders
Stigler, K. A., McDonald, B. C., Anand, A., Saykin, A. J., & McDougle, C. J. (2011) · Brain Research · doi:10.1016/j.brainres.2010.11.076 · Cited by 197 · see citing works
The role of the amygdala in atypical gaze on emotional faces in autism spectrum disorders
Kliemann, D., Dziobek, I., Hatri, A., Baudewig, J., & Heekeren, H. R. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5294-11.2012 · Cited by 183 · see citing works
Stratified medicine for mental disorders
Schumann, G., Binder, E. B., Holte, A., de Kloet, E. R., Oedegaard, K. J., Robbins, T. W., Walker-Tilley, T. R., Bitter, I., Brown, V. J., Buitelaar, J., et al. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.09.010 · Cited by 186 · see citing works
Association between the oxytocin receptor gene and amygdalar volume in healthy adults
Inoue, H., Yamasue, H., Tochigi, M., Abe, O., Liu, X., Kawamura, Y., Takei, K., Suga, M., Yamada, H., Rogers, M. A., et al. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.07.019 · Cited by 164 · see citing works
Domes, G., Kumbier, E., Heinrichs, M., & Herpertz, S. C. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2013.254 · Cited by 160 · see citing works
Elevated amygdala response to faces and gaze aversion in autism spectrum disorder
Tottenham, N., Hertzig, M. E., Gillespie-Lynch, K., Gilhooly, T., Millner, A. J., & Casey, B. J. (2014) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nst050 · Cited by 144 · see citing works
Psychosocial deprivation, executive functions and the emergence of socio-emotional behavior problems
McDermott, J. M., Troller-Renfree, S., Vanderwert, R., Nelson, C. A., Zeanah, C. H., & Fox, N. A. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00167 · Cited by 113 · see citing works
Diagnosing autism in neurobiological research studies
Jones, R. M., & Lord, C. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.10.037 · Cited by 56 · see citing works
“It does not yield meaningful continuous scores but the SCQ has been used as a means to ensure the absence or presence of autistic symptoms in neurotypical participants [66].”
MethodCharbonneau, G., Bertone, A., Lepore, F., Nassim, M., Lassonde, M., Mottron, L., & Collignon, O. (2013) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2013.02.009 · Cited by 54 · see citing works
Scherf, K. S., Elbich, D., Minshew, N., & Behrmann, M. (2015) · NeuroImage Clinical · doi:10.1016/j.nicl.2014.11.003 · Cited by 53 · see citing works
Malisza, K. L., Clancy, C., Shiloff, D., Holden, J., Jones, C., Paulson, K., Yu, D. C. T., Summers, R., & Chudley, A. E. (2011) · ijamh · doi:10.1515/ijamh.2011.055 · Cited by 32 · see citing works
Meaux (2011) · doi:10.1016/j.encep.2010.10.005 · Cited by 15 · see citing works
- Authors
- Corbett, B. A., Carmean, V., Ravizza, S., Wendelken, C., Henry, M. L., Carter, C., & Rivera, S. M.
- Affiliations
- University of California, Davis (US)
- Michigan State University (US)
- University of California, Berkeley (US)
- Stanford University (US)
- Corresponding author
- Corbett, Blythe A.
- Venue
- Psychiatry Research Neuroimaging
- Publisher
- Elsevier BV
- Published
- 2009-09
- Volume
- 173
- Issue
- 3
- Pages
- 196-205
- ISSN
- 0925-4927 (ISSN-L)
- PMC
- PMC2748131
- OpenAlex
- W2112896554
- Cited by
- 227
- References
- 97
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 8 · 2023: 7 · 2022: 10 · 2021: 11 · 2020: 11 · 2019: 11 · 2018: 14 · 2017: 14 · 2016: 11 · 2015: 19 · 2014: 28 · 2013: 22 · 2012: 16
- FWCI
- 7.10
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychiatry Research Neuroimaging (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- U.S. Public Health Service (5 K08NMH072958)
- National Institute of Mental Health (K08MH072958)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- autism spectrum disorder, high-functioning autism, face processing, emotional processing, amygdala, fusiform gyrus, amygdala volume, social anxiety, person matching, children
- MeSH terms
- Autistic Disorder, Brain, Brain Mapping, Child, Emotions, Facial Expression, Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Oxygen, Pattern Recognition, Visual, Photic Stimulation, Surveys and Questionnaires, Reaction Time, Linear Models
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
