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Cited by 314Autism Spectrum Disorder ResearchChild and Adolescent Psychosocial and Emotional DevelopmentChild Nutrition and Feeding Issues

Depression and anxiety symptoms in children and adolescents with autism spectrum disorders without intellectual disability

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Strang, John F., Kenworthy, Lauren, Daniolos, Peter, Case, Laura, Wills, Meagan C., Martin, Alex, Wallace, Gregory L.·2012·Research in Autism Spectrum Disorders
DOI 10.1016/j.rasd.2011.06.015PMC PMC3355529
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Abstract

Recent studies have shown that rates of depression and anxiety symptoms are elevated among individuals with autism spectrum disorders (ASDs) of various ages and IQs and that depression/anxiety symptoms are associated with higher IQ and fewer ASD symptoms. In this study which examined correlates of depression and anxiety symptoms in the full school-age range of children and adolescents (age 6-18) with ASDs and IQs ≥ 70 (n=95), we also observed elevated rates of depression/anxiety symptoms, but we did not find higher IQ or fewer ASD symptoms among individuals with ASDs and depression or anxiety symptoms. These findings indicate an increased risk for depression/anxiety symptoms in children and adolescents with ASDs without intellectual disability, regardless of age, IQ, or ASD symptoms.

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Crossref · 10.1016/j.rasd.2011.06.015

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  • Co-occurring psychiatric and medical disorders are common among individuals with ASD.

    “Co-occurring psychiatric and medical disorders are common among individuals with ASD, with estimates suggesting that 63–78% of individuals with ASD have at least one co-occurring psychiatric condition (Simonoff et al. 2008; Strang et al. 2012), and approximately 10–77% have at least one co-occurring medical condition (Muskens et al. 2017; Betancur 2011).”

    From The Diagnosis of Autism: From Kanner to DSM-III to DSM-5 and Beyond (2021) · cites this paper as Strang et al. 2012

    The Introduction (page unavailable) says psychiatric comorbidities are prevalent and reports secondary psychopathology in as many as 72% of children with ASD. This supports the psychiatric portion attributed to Strang et al., but not the stated 63–78% range for individuals with ASD generally. The medical-condition estimate is cited to other sources, not Strang et al. (LLM, conf=0.86)

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  • Estimates suggest that 63-78% of individuals with ASD have at least one co-occurring psychiatric condition.

    “Co-occurring psychiatric and medical disorders are common among individuals with ASD, with estimates suggesting that 63–78% of individuals with ASD have at least one co-occurring psychiatric condition (Simonoff et al. 2008; Strang et al. 2012), and approximately 10–77% have at least one co-occurring medical condition (Muskens et al. 2017; Betancur 2011).”

    From The Diagnosis of Autism: From Kanner to DSM-III to DSM-5 and Beyond (2021) · cites this paper as Strang et al. 2012

    The Introduction reports that psychiatric comorbidities are prevalent, citing secondary psychopathology in as many as 72% of children with ASD. It does not give the claimed 63–78% range or establish that range for individuals with ASD of all ages; its own Results concern depression and anxiety symptoms, not the prevalence of any psychiatric condition. (LLM, conf=0.86)

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Authors
Strang, J. F., Kenworthy, L., Daniolos, P., Case, L., Wills, M. C., Martin, A., & Wallace, G. L.
Affiliations
  • Children's National (US)
  • National Institutes of Health (US)
Corresponding author
Strang, John F.
ORCID
Venue
Research in Autism Spectrum Disorders
Publisher
Elsevier BV
Published
2012-01
Volume
6
Issue
1
Pages
406-412
ISSN
  • 1878-0237 (ISSN-L)
  • 1750-9467
DOI
10.1016/j.rasd.2011.06.015
PMC
PMC3355529
OpenAlex
W1991589853
Cited by
314
References
35
Citations by year
2026: 8 · 2025: 9 · 2024: 19 · 2023: 17 · 2022: 17 · 2021: 34 · 2020: 38 · 2019: 24 · 2018: 32 · 2017: 22 · 2016: 22 · 2015: 24 · 2014: 22 · 2013: 22 · 2012: 4
FWCI
7.80
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Research in Autism (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • Singer Family Foundation
  • Isadore and Bertha Gudelsky Family Foundation
  • National Institutes of Health
  • Intellectual and Developmental Disabilities Research Center
  • National Institute of Mental Health (U54MH066417, ZIAMH002920)
  • National Center for Research Resources (M01RR013297)
  • NIH Clinical Center
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
Keywords
autism spectrum disorder, depressive symptoms, anxiety symptoms, children and adolescents, intellectual disability, IQ, ASD severity, comorbidities, risk factors

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