Cell-Extracellular Matrix Interactions in Normal and Diseased Skin

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Stem cells find their niche

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Capturing and profiling adult hair follicle stem cells

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Tumors as Organs: Complex Tissues that Interface with the Entire Organism

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Asymmetric cell divisions promote stratification and differentiation of mammalian skin

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TUMOR STROMA AND REGULATION OF CANCER DEVELOPMENT

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Stem cell patterning and fate in human epidermis

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Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells

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Role of integrins in regulating epidermal adhesion, growth and differentiation

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Collagen-based cell migration models in vitro and in vivo

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NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasia

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Stem cells: the generation and maintenance of cellular diversity

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Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

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Skin stem cells: rising to the surface

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c-Jun and JunB Antagonistically Control Cytokine-Regulated Mesenchymal–Epidermal Interaction in Skin

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Cell shape controls terminal differentiation of human epidermal keratinocytes.

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Adhesion, migration and communication in melanocytes and melanoma

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Conditional Ablation of β1 Integrin in Skin

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SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells

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Contribution of stem cells and differentiated cells to epidermal tumours

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Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation

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Molecular Mechanisms of Skin Aging

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A crucial role of β1 integrins for keratinocyte migration in vitro and during cutaneous wound repair

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Loss of TGFβ Signaling Destabilizes Homeostasis and Promotes Squamous Cell Carcinomas in Stratified Epithelia

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Increased PDGFRα Activation Disrupts Connective Tissue Development and Drives Systemic Fibrosis

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Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

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Stem Cell Depletion Through Epidermal Deletion of Rac1

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Signaling via β1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro

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Plasticity of hair follicle dermal cells in wound healing and induction

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Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progressionPreprint

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A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy

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Loss of Kindlin-1 Causes Skin Atrophy and Lethal Neonatal Intestinal Epithelial Dysfunction

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Extracellular Matrix Biomaterials for Soft Tissue Repair

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Epidermal stem cells are retained in vivo throughout skin aging

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The therapeutic potential of stem cells

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Postnatal induction of transforming growth factor β signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma

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Functional and physiological characteristics of the aging skin

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Epidermal stem cell diversity and quiescence

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More than just proliferation: Myc function in stem cells

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New roles for integrins in squamous-cell carcinoma

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Increased Expression of Integrin αvβ5 Induces the Myofibroblastic Differentiation of Dermal Fibroblasts

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Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?

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A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis

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Basement membranes in skin: unique matrix structures with diverse functions?

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MYC in mammalian epidermis: how can an oncogene stimulate differentiation?

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The hair follicle—a stem cell zoo

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Laminin‐10 is crucial for hair morphogenesis

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β1 Integrins Regulate Keratinocyte Adhesion and Differentiation by Distinct Mechanisms

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Transcriptome-based systematic identification of extracellular matrix proteins

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Type VII Collagen Is Required for Ras-Driven Human Epidermal Tumorigenesis

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Epithelial Cells Promote Fibroblast Activation via IL-1α in Systemic Sclerosis

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Down-regulation of LFA-1 Adhesion Receptors by C- myc Oncogene in Human B Lymphoblastoid Cells

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Multiple Functions of the Integrin α6β4 in Epidermal Homeostasis and Tumorigenesis

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Laminin‐332 and ‐511 in skin

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MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma

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Human Skin Aging Is Associated with Reduced Expression of the Stem Cell Markers β1 Integrin and MCSP

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Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesisPreprint

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α3β1 integrin regulates MMP-9 mRNA stability in immortalized keratinocytes: a novel mechanism of integrin-mediated MMP gene expression

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Integrin-linked kinase is required for epidermal and hair follicle morphogenesis

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Exploiting the superior protein resistance of polymer brushes to control single cell adhesion and polarisation at the micron scale

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Switch from αvβ5 to αvβ6 integrin expression protects squamous cell carcinomas from anoikis

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Long-Term Type VII Collagen Restoration to Human Epidermolysis Bullosa Skin Tissue

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Genetic Analyses of Integrin SignalingPreprint

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Involvement of αvβ5 Integrin in the Establishment of Autocrine TGF-β Signaling in Dermal Fibroblasts Derived from Localized Scleroderma

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α3β1 integrin in epidermis promotes wound angiogenesis and keratinocyte-to-endothelial-cell crosstalk through the induction of MRP3

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Expression of Activated MEK1 in Differentiating Epidermal Cells Is Sufficient to Generate Hyperproliferative and Inflammatory Skin Lesions

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Slug Regulates Integrin Expression and Cell Proliferation in Human Epidermal Keratinocytes

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α3β1 integrin–controlled Smad7 regulates reepithelialization during wound healing in mice

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Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signalling

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Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression

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Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate

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A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control

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TNFα shedding and epidermal inflammation are controlled by Jun proteinsPreprint

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A Role for αβ1 Integrins in Focal Adhesion Function and Polarized Cytoskeletal Dynamics

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Hair cycle and wound healing in mice with a keratinocyte-restricted deletion of FAK

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A Laminin-Collagen Complex Drives Human Epidermal Carcinogenesis through Phosphoinositol-3-Kinase Activation

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Decreased expression of keratinocyte beta1 integrins in chronically sun-exposed skin in vivo

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