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Cited by 855

The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.

A novel class of small RNAs in mouse spermatogenic cells

Open access
Grivna, Shane T., Beyret, Ergin, Wang, Zhong, Lin, Haifan·2006·Genes & Development

Abstract

Small noncoding RNAs, including small interfering RNAs (siRNAs) and micro RNAs (miRNAs) of ∼21 nucleotides (nt) in length, have emerged as potent regulators of gene expression at both transcriptional and post-transcriptional levels in diverse organisms. Here we report the identification of a novel class of small RNAs in the mouse male germline termed piwi-interacting RNAs (piRNAs). piRNAs are ∼30 nt in length. They are expressed during spermatogenesis, mostly in spermatids. piRNAs are associated with MIWI, a spermatogenesis-specific PIWI subfamily member of the Argonaute protein family, and depend on MIWI for their biogenesis and/or stability. Furthermore, a subpopulation of piRNAs are associated with polysomes, suggesting their potential role in translational regulation.

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Metadata

Authors
Grivna, S. T., Beyret, E., Wang, Z., & Lin, H.
Venue
Genes & Development
Published
2006-06-09
Volume
20
Issue
13
Pages
1709-1714
ISSN
  • 0890-9369 (ISSN-L)
  • 1549-5477
OpenAlex
W2103012554
Cited by
855
References
24
Type
posted content
Language
en
Open access
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CoChat. (2026). Citation check: A novel class of small RNAs in mouse spermatogenic cells. https://app.cochat.ai/papers/10.1101/gad.1434406
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Grivna, S. T., Beyret, E., Wang, Z., & Lin, H. (2006). A novel class of small RNAs in mouse spermatogenic cells. Genes & Development. https://doi.org/10.1101/gad.1434406

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