CoChat
Sign Up
Cited by 132

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Nanotechnology: emerging tools for biology and medicine

Wong, Ian Y., Bhatia, Sangeeta N., Toner, Mehmet·2013·Genes & Development
DOI 10.1101/gad.226837.113PMC PMC3841729
Open this paper in CoChat — free account

Abstract

Historically, biomedical research has been based on two paradigms. First, measurements of biological behaviors have been based on bulk assays that average over large populations. Second, these behaviors have then been crudely perturbed by systemic administration of therapeutic treatments. Nanotechnology has the potential to transform these paradigms by enabling exquisite structures comparable in size with biomolecules as well as unprecedented chemical and physical functionality at small length scales. Here, we review nanotechnology-based approaches for precisely measuring and perturbing living systems. Remarkably, nanotechnology can be used to characterize single molecules or cells at extraordinarily high throughput and deliver therapeutic payloads to specific locations as well as exhibit dynamic biomimetic behavior. These advances enable multimodal interfaces that may yield unexpected insights into systems biology as well as new therapeutic strategies for personalized medicine.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1101/gad.226837.113

Cites

9 of 9 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Show all 9 references

Research works printed but not linked: 86

  1. 10.1073/pnas.0910781107 · DOI
  2. 10.1126/science.1154533 · DOI
  3. 10.1038/nbt927 · DOI
  4. 10.1021/nn4012847 · DOI
  5. 10.1074/mcp.R200007-MCP200 · DOI · Paper page
  6. 10.1038/nmeth.2027 · DOI
  7. 10.1242/jcs.079509 · DOI · Paper page
  8. 10.1146/annurev-bioeng-071812-152409 · DOI
  9. 10.1038/35093038 · DOI
  10. 10.1038/nbt.1495 · DOI
  11. 10.1038/nphoton.2012.266 · DOI
  12. 10.1146/annurev-bioeng-071811-150118 · DOI
  13. 10.1126/science.1226338 · DOI
  14. 10.1039/c2lc21204h · DOI
  15. 10.1021/nl802511z · DOI
  16. 10.1038/nature08956 · DOI
  17. 10.1038/nmat3550 · DOI
  18. 10.1146/annurev.physiol.62.1.919 · DOI
  19. 10.1073/pnas.0704958104 · DOI
  20. 10.1126/science.1174251 · DOI
  21. 10.1126/science.1214081 · DOI
  22. 10.1038/nrd2552 · DOI
  23. 10.1016/j.ceb.2005.08.015 · DOI
  24. 10.1038/nbt.1507 · DOI
  25. 10.1038/nnano.2007.70 · DOI · Paper page
  26. 10.1039/c2lc21147e · DOI
  27. 10.1038/nnano.2010.237 · DOI
  28. 10.1016/j.cocis.2011.01.005 · DOI
  29. 10.1126/scitranslmed.3003110 · DOI
  30. 2012, Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile, Sci Transl Med, 4, 128ra139
  31. 10.1039/c1lc20524b · DOI
  32. 10.1038/nnano.2010.24 · DOI
  33. 10.1126/science.1227268 · DOI
  34. 10.1083/jcb.201108062 · DOI
  35. 2013, Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease, Nat Biotechnol, 31, 63, 10.1038/nbt.2464 · DOI
  36. 10.1038/nmeth0706-541 · DOI
  37. 10.1038/nm.1711 · DOI · Paper page
  38. 10.1038/nmeth.1531 · DOI
  39. 10.1002/aic.12413 · DOI
  40. 10.1073/pnas.0910603106 · DOI · Paper page
  41. 10.1039/c2lc41104k · DOI
  42. Madou MJ . 2012. Fundamentals of microfabrication and nanotechnology. CRC Press, Boca Raton, FL.
  43. 10.1146/annurev.biophys.36.040306.132646 · DOI
  44. 10.1073/pnas.1010013108 · DOI
  45. 10.1038/nmat2344 · DOI · Paper page
  46. 10.1126/scitranslmed.3000105 · DOI
  47. 10.1038/nature06385 · DOI
  48. 10.1038/nmat2442 · DOI · Paper page
  49. 10.1146/annurev.cellbio.22.010305.104315 · DOI
  50. 2013, Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells, Sci Transl Med, 5, 179ra147
  51. 10.1073/pnas.1011365107 · DOI
  52. 10.1126/science.1136907 · DOI
  53. 10.1038/nrd1304 · DOI
  54. 10.1126/science.1134929 · DOI
  55. 10.1126/scitranslmed.3003778 · DOI
  56. 10.1038/nature04586 · DOI
  57. 10.1002/adma.201200454 · DOI
  58. 10.1021/ac400257c · DOI
  59. 10.1038/nature01406 · DOI
  60. 10.1073/pnas.0909350107 · DOI
  61. 10.1021/nl3042917 · DOI
  62. 10.1038/nm.2994 · DOI
  63. 10.1021/nl102184c · DOI
  64. 10.1016/j.sbi.2010.03.009 · DOI
  65. 10.1126/science.164.3880.717 · DOI
  66. 10.1038/nrm3044 · DOI
  67. 10.1146/annurev.fluid.36.050802.122124 · DOI
  68. 10.1073/pnas.1012539107 · DOI
  69. 10.1016/j.ccr.2009.10.013 · DOI
  70. 10.1038/nm.2182 · DOI · Paper page
  71. 10.1073/pnas.0908201106 · DOI · Paper page
  72. 10.1038/nmat3404 · DOI · Paper page
  73. 10.1146/annurev.bioeng.7.011205.135108 · DOI
  74. 10.1021/nl204051v · DOI
  75. 10.1038/nnano.2011.129 · DOI
  76. 10.1039/b917851a · DOI
  77. 10.1038/nmat3049 · DOI
  78. 10.1002/smll.201100442 · DOI
  79. 10.1002/anie.201005853 · DOI
  80. 10.1021/nl2018838 · DOI
  81. 10.1126/science.1165719 · DOI
  82. 10.1038/nbt872 · DOI
  83. 10.1146/annurev.bioeng.3.1.335 · DOI
  84. 10.1021/nn400874a · DOI
  85. 10.1038/nrd3499 · DOI
  86. 10.1083/jcb.201010021 · DOI

Cited by

Sorted by citations

Metadata

Authors
Wong, I. Y., Bhatia, S. N., & Toner, M.
Venue
Genes & Development
Publisher
Cold Spring Harbor Laboratory
Published
2013-11-15
Volume
27
Issue
22
Pages
2397-2408
ISSN
  • 0890-9369
  • 1549-5477
DOI
10.1101/gad.226837.113
PMC
PMC3841729
Cited by
132
References
9
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review