Noninvasively measuring blood glucose using saliva
Abstract
Self-measurement of blood glucose level is a very important aspect in monitoring the health quality of diabetic patients who require insulin therapy. Typically, a blood sample for analysis is obtained via a finger stick or other such invasive procedure. Often, this blood collecting causes physical and mental stress to the patient. For this reason, it is desirable to establish a noninvasive bloodless procedure to monitor the blood glucose level (BGL). Here, the authors discuss the correlation between BGL and saliva glucose level and then present an approach that uses an enzyme-sensor system to noninvasively measure blood glucose using saliva.
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Salivary glucose can offer an alternative painless screening route for diabetic patients.
“Salivary glucose can thus offer an alternative painless screening route for diabetic patients149-154.”
From Wearable biosensors for healthcare monitoring (2019) · cites this paper as [149]
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Sharma, V., Kapil, D., & Singh, B. (2024) · Process Biochemistry · doi:10.1016/j.procbio.2024.11.023 · Cited by 5 · see citing works
A Saliva-Based Noninvasive Point-of-Care Glucometer
Panwar, S., Aasarey, R., Anand, R., Priya, A., Prakash, S., & Jha, S. K. (2025) · IEEE Sensors Journal · doi:10.1109/jsen.2025.3536293 · Cited by 5 · see citing works
Kapadia, J. (2017) · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · doi:10.7860/jcdr/2017/25580.10250 · Cited by 4 · see citing works
Zheng, R., Pang, L., Peng, Z., Qu, D., Bao, Y., Sun, H., Sun, Z., Guo, S., & Niu, L. (2025) · Angewandte Chemie · doi:10.1002/ange.202511103 · Cited by 2 · see citing works
- Authors
- Yamaguchi, M., Mitsumori, M., & Kano, Y.
- Affiliations
- Tokyo University of Agriculture and Technology (JP)
- ORCID
- Yamaguchi, M.
- Venue
- IEEE Engineering in Medicine and Biology Magazine
- Published
- 1998
- Volume
- 17
- Issue
- 3
- Pages
- 59-63
- ISSN
- 0739-5175 (ISSN-L)
- OpenAlex
- W2052875889
- Cited by
- 129
- References
- 13
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 12 · 2023: 6 · 2022: 4 · 2021: 9 · 2020: 4 · 2019: 7 · 2018: 3 · 2017: 10 · 2016: 14 · 2015: 13 · 2014: 7 · 2013: 1 · 2012: 5
- FWCI
- 1.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- IEEE Engineering in Medicine and Biology Magazine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Sumitomo Foundation
- Saneyoshi Scholarship Foundation
- Topics
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Physical Sciences › Engineering › Biomedical Engineering › Biosensors and Analytical Detection
- Keywords
- non-invasive blood glucose measurement, saliva glucose, blood glucose monitoring, diabetes mellitus, insulin therapy, enzyme biosensor, self-monitoring
- MeSH terms
- Adult, Blood Glucose, Glucose, Humans, Reference Values, Saliva, Time Factors, Reproducibility of Results
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