Cited by 71Electrochemical sensors and biosensorsAnalytical Chemistry and SensorsAdvanced Sensor and Energy Harvesting Materials

Cavitas Sensors: Contact Lens Type Sensors & Mouthguard Sensors

Mitsubayashi, Kohji, Arakawa, Takahiro·2016·Electroanalysis

Abstract

“Cavitas sensors” attached to body cavities such as the contact lens and mouthguard (“no implantable”, “no wearable”) are attracted attention as self‐detachable devices for daily medicine. Many types of contact lens (CL) sensors using electrical and optical methods have been developed for monitoring not only chemicals (glucose, lactate) and electrical conductivity in tear fluid, but also transcutaneous gases at eyelid mucosa. A CL intraocular pressure telemetric sensor has been also commercialized and applied to patients for monitoring the intraocular pressure. Some mouthguard sensors have been investigated for a real‐time measurement of salivary chemicals. A graphene based sensor on tooth enamel was reported to be capable of salivary bacterium detection. Here we review the challenges regarding the integration of biosensors into monitoring for biological information of body cavities. The self‐detachable cavitas sensors are expected to improve the quality of life in the near future.

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Crossref · 10.1002/elan.201600083

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153 of 153 references verified0 citation errors · 0 not checkable

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  • Biomarker molecules in tears diffuse directly from the blood and exhibit close tear-blood concentration correlations.

    “Not only do biomarker molecules in tears diffuse directly from the blood and exhibit close tear–blood concentration correlations, but also tear analysis presents opportunities for the diagnosis of ocular disease.”

    From Wearable biosensors for healthcare monitoring (2019) · cites this paper as [97]

  • Tear analysis presents opportunities for the diagnosis of ocular disease.

    “Not only do biomarker molecules in tears diffuse directly from the blood and exhibit close tear–blood concentration correlations, but also tear analysis presents opportunities for the diagnosis of ocular disease.”

    From Wearable biosensors for healthcare monitoring (2019) · cites this paper as [97]

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Authors
Mitsubayashi, K., & Arakawa, T.
Affiliations
Tokyo Medical and Dental University (JP)
Corresponding author
Mitsubayashi, Kohji
Venue
Electroanalysis
Publisher
Wiley
Published
2016-05-12
Volume
28
Issue
6
Pages
1170-1187
ISSN
  • 1040-0397 (ISSN-L)
  • 1521-4109
OpenAlex
W2393650061
Cited by
71
References
153
Citations by year
2026: 2 · 2025: 5 · 2024: 8 · 2023: 5 · 2022: 7 · 2021: 9 · 2020: 13 · 2019: 10 · 2018: 6 · 2017: 4 · 2016: 2
FWCI
3.38
Type
journal article
Language
en
Open access
closed
Locations
Electroanalysis (publishedVersion)
Funders
Japan Science and Technology Agency (AS2614026M)
Topics
  • Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
  • Physical Sciences › Chemical Engineering › Bioengineering › Analytical Chemistry and Sensors
  • Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
Keywords
contact lens sensor, glucose monitoring, lactate monitoring, intraocular pressure monitoring, salivary biomarkers, graphene sensors, dental enamel, non-invasive monitoring

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