Deformable medical image registration: a survey
Open accessAbstract
Deformable image registration is a fundamental task in medical image processing. Among its most important applications, one may cite: 1) multi-modality fusion, where information acquired by different imaging devices or protocols is fused to facilitate diagnosis and treatment planning; 2) longitudinal studies, where temporal structural or anatomical changes are investigated; and 3) population modeling and statistical atlases used to study normal anatomical variability. In this paper, we attempt to give an overview of deformable registration methods, putting emphasis on the most recent advances in the domain. Additional emphasis has been given to techniques applied to medical images. In order to study image registration methods in depth, their main components are identified and studied independently. The most recent techniques are presented in a systematic fashion. The contribution of this paper is to provide an extensive account of registration techniques in a systematic manner.
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Deformable image registration is a core component of all multi-atlas segmentation (MAS) methods, and the quality of individual registrations has a very high impact on the accuracy of the final segmentation.
“deformable image registration (Sotiras et al., 2013) is a core component of all MAS methods, and the quality of individual registrations has a very high impact on the accuracy of the final segmentation.”
From MUSE: MUlti-atlas region Segmentation utilizing Ensembles of registration algorithms and parameters, and locally optimal atlas selection (2016) · cites this paper as Sotiras et al., 2013
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“x). Here, ddenotes the spatial dimension and xis the spatial coordinate of the xed target image T.Due to the importance of image registration, a large number of dierent approaches have been proposed [1,37,38,39]. Typically, these approaches are formulated as optimization problems, where one seeks to minimize an energy…”
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- Authors
- Sotiras, A., Davatzikos, C., & Paragios, N.
- Affiliations
- University of Pennsylvania (US)
- Venue
- IEEE Transactions on Medical Imaging
- Published
- 2013-07
- Volume
- 32
- Issue
- 7
- Pages
- 1153-1190
- ISSN
- 0278-0062 (ISSN-L)
- 1558-254X
- PMC
- PMC3745275
- OpenAlex
- W2115167851
- Cited by
- 1,587
- References
- 539
- Citations by year
- 2026: 81 · 2025: 121 · 2024: 115 · 2023: 96 · 2022: 115 · 2021: 142 · 2020: 136 · 2019: 126 · 2018: 152 · 2017: 153 · 2016: 130 · 2015: 123 · 2014: 86 · 2013: 9 · 2012: 1
- FWCI
- 18.05
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- IEEE Transactions on Medical Imaging (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- HAL (submittedVersion, other-oa)
- Funders
- National Institute on Aging (R01AG014971)
- National Institute of Mental Health (R01MH070365)
- Topics
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
- Physical Sciences › Physics and Astronomy › Radiation › Advanced Radiotherapy Techniques
- Physical Sciences › Engineering › Biomedical Engineering › Medical Imaging and Analysis
- Keywords
- deformable image registration, medical image registration, multimodal image fusion, statistical atlas, population models, anatomical variation
- MeSH terms
- Algorithms, Diagnostic Imaging, Humans, Image Processing, Computer-Assisted
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